Estimation with Ultimate Quantum Precision of the Transverse Displacement between Two Photons via Two-Photon Interference Sampling Measurements.

We present a quantum sensing scheme achieving the ultimate quantum sensitivity in the estimation of the transverse displacement between two photons interfering at a balanced beam splitter, based on transverse-momentum sampling measurements at the output. This scheme can possibly lead to enhanced high-precision nanoscopic techniques, such as superresolved single-molecule localization microscopy with quantum dots, by circumventing the requirements in standard direct imaging of camera resolution at the diffraction limit, and of highly magnifying objectives. Interestingly, we show that our interferometric technique achieves the ultimate spatial precision in nature irrespectively of the overlap of the two displaced photonic wave packets, while its precision is only reduced of a constant factor for photons differing in any nonspatial degrees of freedom. This opens a new research paradigm based on the interface between spatially resolved quantum interference and quantum-enhanced spatial sensitivity.

Fluorescence lifetime Hong-Ou-Mandel sensing.

Fluorescence Lifetime Imaging Microscopy in the time domain is typically performed by recording the arrival time of photons either by using electronic time tagging or a gated detector. As such the temporal resolution is limited by the performance of the electronics to 100's of picoseconds. Here, we demonstrate a fluorescence lifetime measurement technique based on photon-bunching statistics with a resolution that is only dependent on the duration of the reference photon or laser pulse, which can readily reach the 1-0.1 picosecond timescale. A range of fluorescent dyes having lifetimes spanning from 1.6 to 7 picoseconds have been here measured with only ~1 s measurement duration. We corroborate the effectiveness of the technique by measuring the Newtonian viscosity of glycerol/water mixtures by means of a molecular rotor having over an order of magnitude variability in lifetime, thus introducing a new method for contact-free nanorheology. Accessing fluorescence lifetime information at such high temporal resolution opens a doorway for a wide range of fluorescent markers to be adopted for studying yet unexplored fast biological processes, as well as fundamental interactions such as lifetime shortening in resonant plasmonic devices.

Estimation with Heisenberg-Scaling Sensitivity of a Single Parameter Distributed in an Arbitrary Linear Optical Network.

Quantum sensing and quantum metrology propose schemes for the estimation of physical properties, such as lengths, time intervals, and temperatures, achieving enhanced levels of precision beyond the possibilities of classical strategies. However, such an enhanced sensitivity usually comes at a price: the use of probes in highly fragile states, the need to adaptively optimise the estimation schemes to the value of the unknown property we want to estimate, and the limited working range, are some examples of challenges which prevent quantum sensing protocols to be practical for applications. This work reviews two feasible estimation schemes which address these challenges, employing easily realisable resources, i.e., squeezed light, and achieve the desired quantum enhancement of the precision, namely the Heisenberg-scaling sensitivity. In more detail, it is here shown how to overcome, in the estimation of any parameter affecting in a distributed manner multiple components of an arbitrary M-channel linear optical network, the need to iteratively optimise the network. In particular, we show that this is possible with a single-step adaptation of the network based only on a prior knowledge of the parameter achievable through a "classical" shot-noise limited estimation strategy. Furthermore, homodyne measurements with only one detector allow us to achieve Heisenberg-limited estimation of the parameter. We further demonstrate that one can avoid the use of any auxiliary network at the price of simultaneously employing multiple detectors.