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Phytochemistry ; 215: 113826, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37598993

RESUMO

The fern plant Woodsia ilvensis (L.) R. Br. belongs to the Woodsiaceae family and its leaves are used to treat diarrhea, soft-tissue injuries, and external injuries. Investigations of the compounds obtained from the plasmin-inhibitory-active extracts of W. ilvensis led to the isolation of two undescribed maleimide N-glycosides, an undescribed stilbenoid glycoside, and five undescribed acetylated flavonol bisdesmosides, together with 19 known compounds. The chemical structures of the isolated compounds were determined using spectroscopy. The absolute configurations of the sugar moieties were determined via HPLC after acid hydrolysis. Among the isolated compounds, some flavonoids and stilbenoid glycosides exhibited plasmin-inhibitory activity.


Assuntos
Gleiquênias , Fibrinolisina , Compostos Fitoquímicos , Extratos Vegetais , Fibrinolisina/análise , Flavonoides/química , Glicosídeos/química , Estrutura Molecular , Componentes Aéreos da Planta/química , Extratos Vegetais/química , Gleiquênias/química , Compostos Fitoquímicos/química , Compostos Fitoquímicos/isolamento & purificação , Compostos Fitoquímicos/farmacologia
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