CT anatomy and normal radiography of the skull of the Rhesus monkey (Macaca mulatta).

BACKGROUND: Considering the relationship between human morphology and physiology with the Rhesus monkey, this animal is the most prominent species of laboratory primate for human and animal health research. Moreover, sending Macaca mulatta monkey into space and simulating a living environment for humans shows the similarity of this animal's physiology with humans. OBJECTIVE: So far, no comprehensive study has been done on computed tomography (CT) scan and radiography of skulls in Rhesus monkeys. Therefore, providing accurate documents from the CT anatomy of the skull in these animals can help us to better understand normal conditions and diseases, and we can use a functional atlas of diagnostic imaging from the skull of this animal. METHODS: Ten mature monkeys weighing 6.5 kg were used for this project (five males and five females). A radiographic examination with standard views was performed during general anaesthesia. Then the monkeys were placed in a spherical CT scan during general anaesthesia with standard sternal recumbency. RESULTS: The frontal bone was seen as two parallel radiopaque lines coming forward and downward. The frontal sinus in the Rhesus monkey was not visible in both lateral and dorsoventral radiographs, which could indicate the degeneration of this sinus in this species. The number of teeth in an adult monkey was 32. Molar teeth had a bilophodont arrangement. CONCLUSIONS: The comparison between the size of the eye ball in human and Rhesus monkey, unlike other measured parameters, did not differ much, and this indicates that the volume ratio of the eye ball to the whole skull in Rhesus monkey is higher than that of humans.

CT anatomy of cervical vertebrae of Asian elephant (Elephas maximus).

BACKGROUND: Elephants are currently the largest mammals on earth. A comprehensive examination of the anatomy of this animal to diagnose various disorders is required. In addition, due to the heavy head of these animals, adaptations have been made in the anatomical structure of the neck that is worth studying. OBJECTIVE: This study aimed to investigate a standard morphologic and morphometric description of the elephant cervical spine. Another aim of this study was to compare the changes in the cervical skeleton of elephants with horses and cattle. METHODS: For this study, the cervical vertebrae of the Asian elephant, cattle and horse were examined. CT Images were obtained using Somatom Spirit II CT Machine. Statistical analysis was done by SPSS 24 software. RESULTS: Two dorsal tubercles and a groove between them were observed on the dorsal arch of the atlas vertebra of the Asian elephant. In elephant samples, the variation of vertebral body height, spinous process height, transverse process width, vertebral body length and vertebral foramen volume indices were statistically significant. The volume of the vertebral foramen in the elephant decreases in the second vertebra compared to the first vertebra, decreases in the third vertebra, decreases in the fourth, increases in the fifth, decreases in the sixth and increases in the seventh. CONCLUSIONS: In this study, the structure of the cervical vertebrae of the Asian elephant was examined, and certain features were observed. One of the main features was the reduction of the length of the vertebrae, which leads to the decrease of the ratio of neck length to the size of the body. This condition can be due to the high weight of the head in the elephant. To maintain this weight, it is necessary to reduce the length of the neck and confer less mobility.

Nanoporous platinum needle for cancer tumor destruction by EChT and impedance-based intra-therapeutic monitoring.

Herein, we present a new design on the Single Needle Electrochemical Therapy (SNEChT) method by introducing some major improvements, including a nanoporous platinum electrode, tunable in situ anode size that depends on the width and location of the tumor, and the capability of measuring the efficacy of therapy based in intra-therapeutic impedance recording by the same EChT needle. It could have significant implications in optimizing EChT operative conditions. The nanoporous Pt electrode increased the interactive surface with a tumor, and produced a higher amount of current with lower stimulating DC voltage. The tunable anode size prevents the over-acidification of treated or non-desired lesions. Hence, this feature reduced the over distribution of tissue. Monitoring the impedance during the therapy clearly informs us about the local destruction of the tumor in each location. Thus, we can be informed about the threshold of tissue acidosis with the lowest electrical stimulation. The insertion of one needle with a tunable anode length for both precise therapy and impedance-based intra-therapeutic monitoring will shed new light on the applications of EChT.

Clinical dental finding in Iranian horses.

BACKGROUND: A horse's well-being is directly related to the management of its dental health. A good knowledge of the epidemiology and aetiology of dental disorders could help the owners and clinicians to prevent not only dental problems but also severe gastrointestinal diseases. OBJECTIVES: In this study we report the prevalence of dental disorders in horses in Iran. METHODS: We examined 317 horses randomly in eight provinces in Iran and 21 diseases were characterized in the examined horses. The observed diseases were compared among different breeds, genders and ages of the examined horses. RESULTS: The factor of age among the other three factors was more important in the incidence of diseases because most of the diseases found were significantly different among age groups. Between different breeds examined, only cheek teeth cemental caries in Kurdish and Arabian horses was significantly different (p = .022). Enamel point with an occurrence of 34.4% was the most common disease. Broken cheek teeth were more prevalent in male horses in comparison with female horses (p = .035). CONCLUSION: Our study showed a moderate prevalence of dental disorders in Iranian horse clubs, which could be reduced with better management.