RESUMO
OBJECTIVE: The aim of the article is to establish the interrelation of human biological rhythms and circadian hormones producement as well as to determine their impact on the medicine usage. PATIENTS AND METHODS: Materials and methods: The review and latest data analysis of scientific and medical literature were performed. CONCLUSION: Conclusions: Proceeding from the literature sources there is a firm interrelation between human biological rhythms and circadian hormones producement. Following chronotherapy principles will allow to increase effectiveness of diseases treatment, including dental ones. It will also allow to reduce dosage of prescribed medicines as well as their side effects. Prospects for a further research are to identify a clear relationship between circadian biorhythms in patients with chronic generalized periodontitis in order to increase the effectiveness of therapeutic measures.