Composite Containing Calcium Phosphate Particles Functionalized with 10-MDP.

The phosphate ester monomer 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) is capable of bonding to hydroxyapatite and, for this reason, is a key component of several self-etch adhesives. In this study, dicalcium phosphate dihydrate particles (DCPD; CaHPO4.2H2O) were functionalized with 10-MDP and used to formulate an experimental composite with 50 vol% inorganic content (3:1 DCPD:silanated barium glass ratio) dispersed in a BisGMA/TEGDMA matrix. The tested hypothesis was that DCPD functionalization would improve the composite's mechanical performance without compromising Ca2+ release. Composites containing nonfunctionalized DCPD or only reinforcing glass (in both cases, with or without 10-MDP mixed in the resin phase) were used as controls. Materials were tested for degree of conversion (DC; by Fourier transform infrared spectroscopy), water sorption (WS) and solubility (SL; according to ISO 4049), biaxial flexural strength (BFS)/modulus (FM) after 24 h and 5 mo in water, and 28-d Ca2+ release in water (by plasma-coupled optical emission spectroscopy). Data were analyzed using analysis of variance/Tukey test (alpha: 5%). DCPD functionalization did not interfere with DC. The composite containing functionalized DCPD showed significantly lower WS and SL in comparison with the material formulated with nonfunctionalized particles. The presence of 10-MDP (as a functionalizing agent or dispersed in the resin phase) reduced the composite's initial BFS and FM. After 5 mo in water, the composite with functionalized DCPD and both glass-only composites were able to maintain their mechanical properties at levels statistically similar to what was observed after 24 h. Ca2+ release was significantly reduced in both formulations containing 10-MDP. In conclusion, DCPD functionalization with 10-MDP increased the composite's resistance to hydrolytic degradation, improving its mechanical stability after prolonged water storage. However, the impaired water transit at the particle-matrix interface led to a reduction in Ca2+ release.

[Malignant angiotropic lymphoma. With primary lung involvement]. / Linfoma angiotrópico maligno. Com envolvimento primário do pulmão.

Angiotropic malignant lymphoma (AMLy) is a rare neoplasm characterized by the intravascular proliferation of large lymphoid cells. Most of the cases reported in the literature describe a predominant involvement of the central nervous system and skin. Although any organ may be afflicted, primary involvement of the lung is unusual. We report a case of AMLy in which the pulmonary symptoms dominate the clinical picture. The tumour cells inside the small vessels of the lung were positively identified as B-phenotype lymphoid cells by immunoperoxidase stains for CD-20, which is typical of this aggressive type of lymphoma.

Fosfato e sulfato de cálcio na recuperaçäo de pastagem / Phosphate and calcium sulphate in pasture

Estudou-se o efeito da fertilizaçäo com sulfato de cálcio (gesso agrícola) e com fosfato (termofosfato) em pastagem de capim-braquiária (Brachiaria decumbens Stapf) estabelecida em latossolo vermelho sobre a capacidade de suporte e sobre o rendimento de peso vivo por hectare e por ano da pastagem. As forragens que receberam sulfato de cálcio e fosfato apresentaram níveis mais elevados de proteína bruta, cálcio e fósforo. Verificou-se também maior taxa de lotaçäo e maior rendimento em peso vivo por hectare nas pastagens que receberam fertilizaçäo

Sistemas de indicadores de saúde e ambiente em instituições de saúde

Revisão teórica sobre aspectos conceituais e metodológicos da construção de um sistema de indicadores, visando a gestão integrada em saúde e ambiente nas instituições de pesquisa, ensino e prestação de serviços em saúde, que articule também a Biossegurança. Partiu-se do estudo de modelos internacionais de indicadores, destacando-se o modelo da Organização Mundial de Saúde, mais apropriado para este trabalho, a partir do qual foi feito o processo de coleta, organização e síntese de informações. Visa-se criar um instrumental de monitoramento e avaliação destas ações, a fim de apoiar a tomada de decisões.