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1.
J Homosex ; : 1-22, 2024 Jan 09.
Artigo em Inglês | MEDLINE | ID: mdl-38193863

RESUMO

This qualitative research uses a case study to observe non-binary representation in TV fiction. The Dan character from the Spanish series HIT (RTVE, 2020-present), who is the first openly non-binary character in Spanish TV fiction, is analyzed through the lens of Queer Media Studies. The research applies a combination of content and discourse analysis. Qualitative content categories include a character's visibility, identity, relevance, embodiment, and social interaction. Discourse analysis categories include character's construction, lexicalization, propositional framing, and focus. Results show that Dan's non-binary depiction revolves around three significant axes: dualism, confusion, and exceptional talent. These axes frame social attitudes toward non-binary people and are composed by a set of features identified in Dan's case which also informs society's mind-sets. These traits are proposed as an analytical-theoretical tool for further analyses of non-binary representation in different cultural contexts. The outcomes of this research may inform audiovisual industries, regulations and academia, and are useful to consolidate non-binary media studies.

2.
Microbiol Spectr ; 11(3): e0534622, 2023 06 15.
Artigo em Inglês | MEDLINE | ID: mdl-37191534

RESUMO

The first 18 months of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in Colombia were characterized by three epidemic waves. During the third wave, from March through August 2021, intervariant competition resulted in Mu replacing Alpha and Gamma. We employed Bayesian phylodynamic inference and epidemiological modeling to characterize the variants in the country during this period of competition. Phylogeographic analysis indicated that Mu did not emerge in Colombia but acquired increased fitness there through local transmission and diversification, contributing to its export to North America and Europe. Despite not having the highest transmissibility, Mu's genetic composition and ability to evade preexisting immunity facilitated its domination of the Colombian epidemic landscape. Our results support previous modeling studies demonstrating that both intrinsic factors (transmissibility and genetic diversity) and extrinsic factors (time of introduction and acquired immunity) influence the outcome of intervariant competition. This analysis will help set practical expectations about the inevitable emergences of new variants and their trajectories. IMPORTANCE Before the appearance of the Omicron variant in late 2021, numerous SARS-CoV-2 variants emerged, were established, and declined, often with different outcomes in different geographic areas. In this study, we considered the trajectory of the Mu variant, which only successfully dominated the epidemic landscape of a single country: Colombia. We demonstrate that Mu competed successfully there due to its early and opportune introduction time in late 2020, combined with its ability to evade immunity granted by prior infection or the first generation of vaccines. Mu likely did not effectively spread outside of Colombia because other immune-evading variants, such as Delta, had arrived in those locales and established themselves first. On the other hand, Mu's early spread within Colombia may have prevented the successful establishment of Delta there. Our analysis highlights the geographic heterogeneity of early SARS-CoV-2 variant spread and helps to reframe the expectations for the competition behaviors of future variants.


Assuntos
COVID-19 , Humanos , Teorema de Bayes , COVID-19/epidemiologia , Colômbia/epidemiologia , SARS-CoV-2/genética
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