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Eur Heart J Acute Cardiovasc Care ; 9(3): 204-208, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32352314

RESUMO

COVID-19 has developed into a pandemic, hitting hard on our communities. As the pandemic continues to bring health and economic hardship, keeping mortality as low as possible will be the highest priority for individuals; hence governments must put in place measures to ameliorate the inevitable economic downturn. The course of an epidemic may be defined by a series of key factors. In the early stages of a new infectious disease outbreak, it is crucial to understand the transmission dynamics of the infection. The basic reproduction number (R0), which defines the mean number of secondary cases generated by one primary case when the population is largely susceptible to infection ('totally naïve'), determines the overall number of people who are likely to be infected, or, more precisely, the area under the epidemic curve. Estimation of changes in transmission over time can provide insights into the epidemiological situation and identify whether outbreak control measures are having a measurable effect. For R0 > 1, the number infected tends to increase, and for R0 < 1, transmission dies out. Non-pharmaceutical strategies to handle the epidemic are sketched and based on current knowledge, the current situation is sketched and scenarios for the near future discussed.


Assuntos
Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/mortalidade , Surtos de Doenças/prevenção & controle , Controle de Infecções/tendências , Pneumonia Viral/epidemiologia , Pneumonia Viral/mortalidade , Insuficiência Respiratória/terapia , Doença Aguda , Número Básico de Reprodução , Betacoronavirus , COVID-19 , Controle de Doenças Transmissíveis , Infecções por Coronavirus/transmissão , Transmissão de Doença Infecciosa/classificação , Transmissão de Doença Infecciosa/prevenção & controle , Humanos , Hipóxia/etiologia , Pandemias , Pneumonia Viral/transmissão , Respiração Artificial/métodos , Insuficiência Respiratória/etiologia , SARS-CoV-2 , Latência Viral/fisiologia
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