Interfacial Polarization Locked Flexible ß-Phase Glycine/Nb2 CTx Piezoelectric Nanofibers.

Biomolecular piezoelectric materials show great potential in the field of wearable and implantable biomedical devices. Here, a self-assemble approach is developed to fabricating flexible ß-glycine piezoelectric nanofibers with interfacial polarization locked aligned crystal domains induced by Nb2 CTx nanosheets. Acted as an effective nucleating agent, Nb2 CTx nanosheets can induce glycine to crystallize from edges toward flat surfaces on its 2D crystal plane and form a distinctive eutectic structure within the nanoconfined space. The interfacial polarization locking formed between O atom on glycine and Nb atom on Nb2 CTx is essential to align the ß-glycine crystal domains with (001) crystal plane intensity extremely improved. This ß-phase glycine/Nb2 CTx nanofibers (Gly-Nb2 C-NFs) exhibit fabulous mechanical flexibility with Young's modulus of 10 MPa, and an enhanced piezoelectric coefficient of 5.0 pC N-1 or piezoelectric voltage coefficient of 129 × 10-3 Vm N-1 . The interface polarization locking greatly improves the thermostability of ß-glycine before melting (≈210°C). A piezoelectric sensor based on this Gly-Nb2 C-NFs is used for micro-vibration sensing in vivo in mice and exhibits excellent sensing ability. This strategy provides an effective approach for the regular crystallization modulation for glycine crystals, opening a new avenue toward the design of piezoelectric biomolecular materials induced by 2D materials.

Soft ferroelectret ultrasound receiver for targeted peripheral neuromodulation.

Bioelectronic medicine is a rapidly growing field where targeted electrical signals can act as an adjunct or alternative to drugs to treat neurological disorders and diseases via stimulating the peripheral nervous system on demand. However, current existing strategies are limited by external battery requirements, and the injury and inflammation caused by the mechanical mismatch between rigid electrodes and soft nerves. Here we report a wireless, leadless, and battery-free ferroelectret implant, termed NeuroRing, that wraps around the target peripheral nerve and demonstrates high mechanical conformability to dynamic motion nerve tissue. As-fabricated NeuroRing can act as an ultrasound receiver that converts ultrasound vibrations into electrostimulation pulses, thus stimulating the targeted peripheral nerve on demand. This capability is demonstrated by the precise modulation of the sacral splanchnic nerve to treat colitis, providing a framework for future bioelectronic medicines that offer an alternative to non-specific pharmacological approaches.

Comprehensive control of PM 2.5 capture and ozone emission in two-stage electrostatic precipitators.

Indoor air purification is extremely urgent to eliminate the health threat of PM 2.5, VOCs and microbial aerosol for exposing people, for which ESPs enjoy exceptional advantage for its special high-voltage characteristic. However, the secondary air pollutant of ozone is produced to possibly cause potential risk. In this work, six kinds of two-stage ESPs containing various charger and collector units, whose structure and size design are determined according to the indoor application, are developed to investigate the comprehensive control of PM 2.5 capture and ozone emission. Responsive surface methodology is employed to explore the relationship among ozone concentration, wire number, charger current and airflow velocity, and obtain regression model for predicting ozone emission. The comprehensive evaluation standard considering efficiency-ozone double factors is proposed to optimize structure design and working conditions of two-stage ESPs. Experimental results show that two-stage ESPs with a unit ratio of >3/4 can keep relatively good stable state, whose current reduction is in around 10 µA, for preventing particle charging function of charger from basically affecting. For the two-stage ESP with Ra = 2/5, it finds the optimization of working conditions of collector can bring rapid improvement of collection efficiency for 0.25 µm particles, which reaches up to be >60 %, while the optimization of that of the charger can only result in an enhancement of <30 %. RSM analysis exhibits a strong connection between the interactive effect of charger current and airflow velocity for presenting a steep response surface. Based on comprehensive control of PM 2.5 and ozone pollutants, it suggests the two-stage ESP with Ra = 2/5 is selected at the first priority and then that with Ra = 1/6, while two-stage ESP with Ra = 4/3 is not recommended for unsatisfied consequence of both of PM 2.5 capture and ozone emission.

Advances in applications of piezoelectronic electrons in cell regulation and tissue regeneration.

Bioelectricity plays a significant role in major biological processes and electrical stimulation is an effective and non-invasive way to promote cellular growth, differentiation and tissue regeneration. In tissue engineering, piezoelectric materials not only act as modulators to regulate behaviors and functions of cells and tissues, but are also used as scaffolds to regulate and guide cell growth and matrix synthesis, thus promoting the formation of new tissue. Piezoelectronic electrons are produced from piezoelectric materials upon mechanical stimuli and have similar effects on cells as an external electrical field. Devices based on piezoelectronics have been widely applied in bioelectronics and biomedical fields. In this review, the effects of piezoelectronic electrons on cells and their possible mechanisms are briefly introduced. Then, we overview the applications of piezoelectronic electrons in cell regulation and tissue regeneration according to the type of cells and tissues. Finally, future perspectives and challenges are also provided.

Biofeedback electrostimulation for bionic and long-lasting neural modulation.

Invasive electrical stimulation (iES) is prone to cause neural stimulus-inertia owing to its excessive accumulation of exogenous charges, thereby resulting in many side effects and even failure of nerve regeneration and functional recovery. Here, a wearable neural iES system is well designed and built for bionic and long-lasting neural modulation. It can automatically yield biomimetic pulsed electrical signals under the driven of respiratory motion. These electrical signals are full of unique physiological synchronization can give biofeedback to respiratory behaviors, self-adjusting with different physiological states of the living body, and thus realizing a dynamic and biological self-matched modulation of voltage-gated calcium channels on the cell membrane. Abundant cellular and animal experimental evidence confirm an effective elimination of neural stimulus-inertia by these bioelectrical signals. An unprecedented nerve regeneration and motor functional reconstruction are achieved in long-segmental peripheral nerve defects, which is equal to the gold standard of nerve repair -- autograft. The wearable neural iES system provides an advanced platform to overcome the common neural stimulus-inertia and gives a broad avenue for personalized iES therapy of nerve injury and neurodegenerative diseases.

Removal of hexanal in cooking fume by combination of storage and plasma-catalytic oxidation on alkali-modified Co-Mn solid solution.

Cooking oil fumes as an important source of volatile organic compounds in metropolitan areas are poisonous to the environment and human health. In this study, the removal of hexanal (a representative of cooking fume) using "storage-plasma catalytic oxidation" at ambient conditions has been investigated. Alkali-modified Co-Mn catalysts were synthesized by coprecipitation method and further characterized by XRD, SEM, N2 adsorption-desorption, H2-TPR, O2-TPD and XPS techniques. It was clearly shown that the Na modification afforded a remarkable enhancement in the hexanal storage capacity, which is ascribed to the formation of surface hydroxyls that resulted in the chemical adsorption. Moreover, the plasma-catalytic oxidation results showed 99.4% hexanal removal and 85.7% CO2 selectivity at a GHSV of 47700 h-1. XPS results revealed that Na modification promoted the formation of more abundant Co3+, Mn3+ cations and surface adsorbed oxygen species, thus facilitated the oxidation process. In-situ FTIR results revealed that Na modification could trigger disproportionation reaction, resulting in the transformation of adsorbed hexanal into alcohol and carboxylic acid thus further speeds up the oxidation rate. This work provides a low-cost, highly efficient and energy-consuming approach for the removal of gaseous cooking fume by storage and plasma catalytic oxidation cycle at room temperature.

Enhanced visible light photocatalytic activity of BiOBr by in situ reactable ionic liquid modification for pollutant degradation.

In this study, hierarchical BiOBr microspheres were synthesized via a one-pot solvothermal method in the presence of imidazole ionic liquids. The resultant samples were characterized by XRD, SEM, HRTEM, PL, EPR, EIS and UV-vis absorption spectroscopy. The photoactivity of BiOBr was evaluated by the photocatalytic degradation of methyl orange (MO) and tetracycline hydrochloride. Oxygen vacancies were detected in the system and proven to be correlated with the activity of the catalyst. It was also revealed that BiOBr microspheres prepared by 1-butyl-3-methylimidazolium bromide at 433 K for 8 hours displayed a superior performance compared to the other samples in the degradation of model organic contaminants. After 4.5 hours of reaction, the highest degradation efficiency of 94.0% was achieved by BiOBr-C4-Br. Stronger photoluminescence spectral intensities could be obtained as the cationic chain lengths of the ionic liquids reduced gradually. According to our experiments, the better performance of BiOBr-C4-Br in the degradation of model pollutants can be attributed to the effect of oxygen vacancies. The findings of our work may have important implications for the design of BiOBr.