Função sexual, sintomatologia depressiva e qualidade de vida de pessoas submetidas à terapia hemodialítica / Función sexual, síntomas depresivos y calidad de vida de las personas en tratamiento de hemodiálisis / Sexual function, depressive symptoms and quality of life of people undergoing hemodialysis therapy

RESUMO Objetivo analisar a correlação entre função sexual, sintomatologia depressiva e qualidade de vida de pessoas em tratamento hemodialítico. Método estudo transversal desenvolvido com 54 participantes. A coleta de dados ocorreu entre os meses de março a maio de 2020. Os dados foram analisados com os testes de Mann-Whitney e Correlação de Spearman, com intervalo de confiança de 95%. Resultados a correlação entre a função sexual e a sintomatologia depressiva somente foi clinicamente relevante para as mulheres (ρ= -0,724). Já em relação à qualidade de vida, observou-se que a função sexual geral dos homens está negativamente correlacionada com a dimensão dor (ρ= -0,349) e com a função social (ρ= -0,347). Já para as mulheres, a função sexual geral está positivamente correlacionada com a função física (ρ= 0,501), saúde geral (ρ= 0,737), componente mental (ρ= 0,497), sono (ρ= 0,753), qualidade da interação social (ρ= 0,621) e com a satisfação do paciente (ρ= 0,457). Conclusão e implicações para a prática o aumento da função sexual esteve fortemente correlacionado com a redução de sintomatologia depressiva e com o aumento da qualidade de vida, implicando a necessidade de fortalecer as abordagens sexuais por meio de protocolos que ofereçam fluxos de encaminhamento às equipes transdisciplinares especializadas.

RESUMEN Objetivo analizar la correlación entre función sexual, síntomas depresivos y calidad de vida de personas en hemodiálisis. Método estudio transversal desarrollado con 54 participantes. La recolección de datos ocurrió entre marzo y mayo de 2020. Los datos fueron analizados mediante las pruebas de Mann-Whitney y Correlación de Spearman, con un intervalo de confianza del 95%. Resultados la correlación entre la función sexual y los síntomas depresivos solo fue clínicamente relevante para las mujeres (ρ= -0,724). En cuanto a la calidad de vida, se observó que la función sexual general de los hombres se correlaciona negativamente con la dimensión dolor (ρ= -0,349) y con la función social (ρ= -0,347). Para las mujeres, la función sexual general se correlaciona positivamente con la función física (ρ= 0,501), salud general (ρ= 0,737), componente mental (ρ= 0,497), sueño (ρ= 0,753), calidad de la interacción social (ρ= 0,621) y con la satisfacción del paciente (ρ= 0,457). Conclusión e implicaciones para la práctica el aumento de la función sexual se correlacionó fuertemente con la reducción de los síntomas depresivos y con el aumento de la calidad de vida, lo que implica la necesidad de fortalecer los abordajes sexuales a través de protocolos que ofrezcan flujos de derivación para equipos transdisciplinarios especializados.

Objective to analyze the correlation between sexual function, depressive symptomatology and quality of life of people on hemodialysis treatment. Method a cross-sectional study developed with 54 participants. Data collection occurred between the months of March and May 2020. The data were analyzed with the Mann-Whitney and Spearman Correlation tests, with a 95% confidence interval. Results the correlation between sexual function and depressive symptomatology was only clinically relevant for women (ρ= -0.724). Regarding quality of life, it was observed that the overall sexual function of men is negatively correlated with the pain dimension (ρ= -0.349) and with the social function (ρ= -0.347). For women, overall sexual function is positively correlated with physical function (ρ= 0.501), general health (ρ= 0.737), mental component (ρ= 0.497), sleep (ρ= 0.753), quality of social interaction (ρ= 0.621), and patient satisfaction (ρ= 0.457). Conclusion and implications for the practice increased sexual function was strongly correlated with reduced depressive symptoms and increased quality of life, implying the need to strengthen sexual approaches through protocols that provide referral flows to specialized trans-disciplinary teams.

The relationship between cannabidiol and psychosis: A review.

BACKGROUND: Cannabis sativa is the most widely used illicit drug in the world. There is concern about its harmful effects, especially because of increasing potency, which has been reported globally. These effects seem to result from the relationship among its components, notably delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), which have opposite effects. THC is considered responsible for the main psychotropic effects of the drug, while CBD seems to antagonize these effects, particularly those that induce psychosis. METHODS: We performed a PubMed literature review of research discussing the association of cannabidiol and psychosis published from 2006 to July 2014. RESULTS: The effects of Cannabis seem to depend on several variables related to the type of plant, its strength, usage patterns, and intersubjective variations. CBD could be used to treat several conditions, including psychosis, when the current treatment is associated with significant side effects. CONCLUSIONS: Because of the complexity of the subject, including limitations and contradictions in studies available to date, further research involving the possible antipsychotic effect and other potential positive effects of Cannabis are needed. There also are noteworthy differences between the research design parameters and recreational use of Cannabis.