"I tried to appreciate it in a different way": Older lesbian, bisexual, and queer women's body image and embodiment across the life course.

We examined the life histories of older lesbian, bisexual, and queer women, focusing on the stories they told about their bodies and sexuality from early to later life. Guided by a narrative constructionist approach, a series of two life history interviews were conducted with 17 lesbian, bisexual, and queer women aged 65-86. Two themes were constructed through a narrative thematic analysis: Queering the Corset: Negotiating Gender Expression and (Aspirational) Aging Body Acceptance. Participants experienced body-related freedom through 'tomboy' expressions of physicality as children. This body autonomy was constrained in adolescence and adulthood due to heterosexist messages surrounding idealized femininity relayed by family and (heterosexual) men, which disrupted self-care yet catalyzed attuned, queer desire and positive embodiment. Women worked to accept their bodies as they aged; they experienced some body dissatisfaction in relation to age-related body changes, yet gratitude and pride in their older queer identities. The findings highlight concurrent positive and negative body image, and breadth of body-related experiences ranging from attunement and agency to discomfort and disruption throughout the life course. This work contributes to body image and embodiment research by moving beyond dominant (youthful) heteronormative perspectives by illuminating how ageism and heterosexism can shape body-related experiences.

Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration.

Traumatic brain injury (TBI) affects at least 3 M people annually. In humans, repetitive mild TBI (rmTBI) can lead to increased impulsivity and may be associated with chronic traumatic encephalopathy. To better understand the relationship between repetitive TBI (rTBI), impulsivity and neuropathology, we used CHIMERA (Closed-Head Injury Model of Engineered Rotational Acceleration) to deliver five TBIs to rats, which were continuously assessed for trait impulsivity using the delay discounting task and for neuropathology at endpoint. Compared to sham controls, rats with rTBI displayed progressive impairment in impulsive choice. Histological analyses revealed reduced dopaminergic innervation from the ventral tegmental area to the olfactory tubercle, consistent with altered impulsivity neurocircuitry. Consistent with diffuse axonal injury generated by CHIMERA, white matter inflammation, tau immunoreactivity and degeneration were observed in the optic tract and corpus callosum. Finally, pronounced grey matter microgliosis was observed in the olfactory tubercle. Our results provide insight into the mechanisms by which rTBI leads to post-traumatic psychiatric-like symptoms in a novel rat TBI platform.