[The postnatal condition evaluation of preterm infants]. / Ocena stanu noworodków urodzonych przedwczesnie.

OBJECTIVE: The aim of the study was to compare general postnatal condition of preterm infants delivered by caesarean section or born vaginally. MATERIAL AND METHODS: The study group consisted of 605 premature newborns delivered in Obstetrics and Gynaecology Clinic of Medical University of Warsaw in 1995-2000. The newborns were divided into two groups. There were 280 prematures delivered by caesarean section in the first group and 325 ones were born vaginally in the second group. RESULTS: The first day mortality rate in infants born vaginally was 6.8% comparing with 2.8% in ones delivered by caesarean section. CONCLUSIONS: In the study group the percentage of neonatal severe condition was similar in both groups but mortality rate in the first day of life was slightly higher in infants born vaginally.

[Pregnancy delivery and newborn in female kidney recipients]. / Ocena przebiegu ciazy i porodu oraz stanu noworodków u pacjentek po transplantacji nerki.

OBJECTIVE: During the past few years a great development of clinical transplantology has taken place. Organ transplantation permits the best and quickest biological, clinical and social rehabilitation of patients. The subsidence of hormonal disturbances, which are responsible for irregular ovarian cycles and ovulation, has been observed among women with stable graft function. Such patients often become capable of conceiving and possessing offspring. With an increasing frequency of such occurrences, the pregnancy and delivery in the female transplant recipients is now becoming one of the major problem of contemporary perinatology. The aim of this study was to summarize our experience with the pregnancy, delivery and the state of newborn in female kidney transplant recipients. MATERIALS AND METHODS: 25 female kidney-transplant recipients who became pregnant were observed during pregnancy. The age of the patient was between 23 and 38 years. 32 pregnancies were followed up. The duration and complications of pregnancy, mode of delivery and newborns condition were analyzed. RESULTS: Miscarriages were observed in 47% of cases. Among patients who got birth, premature delivery was observed in 53%. Two stillbirths took place. 91% neonates were born in good condition. Preterm delivery occurred in 53%. Average birth weight was lower then observed at healthy pregnant women. No congenital defects were observed. CONCLUSIONS: In kidney transplant recipients who became pregnant the increased incidence of spontaneous abortion and preterm delivery was observed. Newborns delivered by those patients had decreased birth weight. No congenital defects were noted among those babies.

[Menstrual abnormalities in women with biliary cirrhosis treated with liver transplantation]. / Leczenie nieprawidlowych krwawien z dróg rodnych u kobiet po transplantacji watroby- opis dwóch przypadków.

A study presents two cases of menstrual abnormalities in women with primary biliary cirrhosis and chronic active hepatitis treated with liver transplantation. The gonadotropin, sex hormones levels and biochemical parameters were presented. The menstrual disorders we observed may be a consequence of high concentration of oestrogens in our patients.

[Menstrual cycle in women with Wilson disease before and after liver transplantation]. / Ocena cyklu miesiaczkowego u pacjentek z choroba Wilsona leczonych przeszczepieniem watroby.

Four cases of young women with Wilson's disease who underwent liver transplantation are presented. The menstrual disturbances associated with Wilson's disease are presented and discussed.

[The effectiveness of prenatal steroid and ambroxol therapy for the prevention of respiratory distress syndrome in newborns of diabetic mothers]. / Profilaktyka zaburzen oddychania noworodków u ciezarnych z przedciazowa cukrzyca insulinozalezna.

The aim of the study was to determine the effectiveness of antenatal steroids and ambroxol in reduction of respiratory distress syndrome (RDS) in newborns of diabetic mothers. A retrospective chart review was done on 101 diabetic gravidas who were hospitalised at 1st Department of Obstetrics and Gynaecology Medical University in Warsaw between January 1989 and December 1999. We studied the neonatal outcomes for women with diabetes mellitus who delivered before 37 gestational weeks depend on exposition to antenatal steroids or ambroxol. Both groups were compared with unexposed neonates for respiratory distress syndrome. Frequency of occurrence and severity of RDS were similar in all study subgroups. We did not found reduction of respiratory distress syndrome in newborns of diabetic mothers exposed to antenatal steroids or ambroxol.

[The influence of prenatal glucocorticoids on glycemic control among pregnant women with type I diabetes]. / Wplyw sterydoterapii stosowanej w profilaktyce zaburzen oddychania na gospodarke weglowodanowa ciezarnych z cukrzyca przedciazowa insulinozalezna.

The purpose of this study was to determine the impact of glucocorticoids treatment, administered for a severe risk of premature delivery. The study material consisted of 30 diabetic mothers treated with intensive insulin therapy. The effects of steroid treatment on glucose level two days prior, one day prior, during 1-, or 2-, or 3-days therapy and the first 2 days following treatment were determined. No case of ketoacidosis was reported.

[Cytodiagnosis of cervical cancer: efficacy of the passive preventive care]. / Cytodiagnostyka raka szyjki macicy--skutecznosc profilaktyki biernej.

339 women were given a questionnaire and asked for the frequency of Pap smear for the last 10 years. The occurrence of cytological exam depends on the age, education, time of employment and number of children and is independent of the place of residence.

[Hemoglobin level analysis in the pregnancy complicated by rhesus isoimmunization]. / Ocena parametrów morfologii krwi plodów u pacjentek z immunizacja w ukladzie rh.

In 19 red blood cell isoimmunized pregnancies with the Coombs' titer lower than 1:32, the haemoglobin level was measured. The values were compared to reference ranges of mean for gestational age. In four cases the intravascular transfusion was performed. Six fetuses were Rh negative.

[Feto-maternal immunization and fetal hemolytic disease: invasive diagnostics and therapy in the Warsaw center of serological collision in years 1992-1999]. / Immunizacja matczyno-plodowa i choroba hemolityczna plodu--inwazyjna diagnostyka i terapia w stolecznym osrodku konfliktu serologicznego w latach 1992-1999.

OBJECTIVE: The objective of this study was the assessment of intrauterine procedures, which are performed during the diagnostic phase and therapy of fetal hemolytic disease in the Warsaw Center of Serological Collision. MATERIALS AND METHODS: The study covered 146 women, who were patients of the Center from 1992 to 1999. Analyzed were the time of commencement of diagnostic and treatment, type of operations, duration of therapy, time and manner of delivery after the past intrauterine procedures, the medical condition of infants born as a result of these deliveries and the necessity for blood treatment in the early neonatal stage. RESULTS: 451 intrauterine procedures were carried out, of which 159 were diagnostic punctures of the umbilical vessel and 292 were fetal transfusions. The diagnostics and treatment was performed between the 19 and 38 week of pregnancy. The number of punctures for each patient ranged from 1 to 4, and 1 to 10 for intrauterine transfusions. The therapy, which on average lasted 42 days, significantly improved the fetal blood morphology results. During the therapy 5 intrauterine demises were noted--3 as a result of advanced fetal hemolytic disease and 2 related to operation complications. The average pregnancy duration in the analyzed group was 36.4 for treated women and 37.4 weeks for diagnosed women. 52.7% of deliveries were vaginal, 47.3% were performed by cesarean section. The general condition of 87% of infants was good. However, 77% of infants required blood treatment during the early neonatal period. CONCLUSIONS: Invasive methods of fetal hemolytic disease diagnostics and intrauterine therapy assure high efficiency in the guiding of serological collision and fetal hemolytic disease conflicted pregnancies. At the same time, these methods are safe and carry a low risk of complications.