RESUMO
This retrospective study was aimed to compare the perioperative complications for internal carotid artery stenosis (ICS) in a Japanese single institute between the use of carotid artery stenting (CAS) alone or the use of an appropriate individualized treatment method allowing either carotid endarterectomy (CEA) or CAS based on patient risk factors. Based on the policy at our hospital, only CAS was performed on patients (n = 33) between January 2005 and November 2009. From December 2009 to December 2012, either CEA or CAS (tailored treatment) was selected for patients (n = 61) based on individual patient risk factors. CEA was considered the first-line treatment in all cases. In high-risk CEA cases, CAS was performed instead (n = 11), whereas in low-risk CEA cases, CEA was performed (n = 19). Further, in moderate-risk CEA cases based on own criteria, CAS was considered first, whereas for high-risk CAS cases, CEA was performed (n = 17). For low-risk CAS cases, CAS was performed (n = 9). Perioperative clinical complications (any stroke, myocardial infarction, or death within 30 days) were compared between both periods. Significantly reduced perioperative complications were observed during the tailored period (4/61 sites, 6.6%) as compared with the CAS period (8/33 sites, 24.2%) [Fisher's exact test p = 0.022; odds ratio, 4.56 (CAS/tailored); 95% confidence interval, 1.26-16.5]. Selecting an appropriate individualized treatment method according to patient risk factors, as opposed to adhering to a single treatment approach such as CAS, may contribute to improved overall outcomes in patients with ICS.
Assuntos
Estenose das Carótidas/cirurgia , Endarterectomia das Carótidas , Complicações Pós-Operatórias/prevenção & controle , Stents , Idoso , Estenose das Carótidas/diagnóstico , Estenose das Carótidas/mortalidade , Causas de Morte , Hemorragia Cerebral/mortalidade , Hemorragia Cerebral/prevenção & controle , Infarto Cerebral/mortalidade , Infarto Cerebral/prevenção & controle , Terapia Combinada , Feminino , Humanos , Ataque Isquêmico Transitório/mortalidade , Ataque Isquêmico Transitório/prevenção & controle , Japão , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/diagnóstico , Infarto do Miocárdio/mortalidade , Infarto do Miocárdio/prevenção & controle , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/mortalidade , Medicina de Precisão , Estudos Retrospectivos , Medição de Risco , Acidente Vascular Cerebral/diagnóstico , Acidente Vascular Cerebral/mortalidade , Acidente Vascular Cerebral/prevenção & controleRESUMO
BACKGROUND: Moyamoya disease more commonly occurs in young people and women, so patients with this disease may experience pregnancy and delivery. Cesarean section (CS) is often chosen as the mode of delivery for these patients in Japan. No appropriate mode of delivery has yet been established for pregnant women with moyamoya disease in terms of stroke prevention. We have used vaginal delivery under epidural analgesia (EA) in such patients unless CS has been indicated for the maternal or fetal reasons. This study retrospectively analyzed our patients with moyamoya disease who gave birth to confirm the safety of vaginal delivery under EA. METHODS: Twelve consecutive patients diagnosed with moyamoya disease had 14 deliveries at our hospital between September 2004 and January 2013. The incidences of intrapartum stroke were compared between cases of vaginal delivery under EA and CS cases. RESULTS: Ten vaginal deliveries under EA and 4 elective CSs were performed. No intrapartum stroke was observed during either vaginal delivery under EA or CS. Among the patients who underwent vaginal delivery under EA, 1 parturient who experienced 2 deliveries suffered transient ischemic attack during both postpartum periods. All 14 infants were healthy without sequelae. CONCLUSIONS: Vaginal delivery under EA is an option for patients with moyamoya disease, provided that close cooperation with neurosurgeons, obstetricians, and anesthesiologists is assured.
Assuntos
Analgesia Epidural , Parto Obstétrico/métodos , Doença de Moyamoya/cirurgia , Acidente Vascular Cerebral/etiologia , Adulto , Analgesia Epidural/efeitos adversos , Cesárea , Parto Obstétrico/efeitos adversos , Feminino , Humanos , Doença de Moyamoya/complicações , Gravidez , Estudos RetrospectivosRESUMO
This study examined the impact of platelet transfusion (PLT) on the survival of intracerebral hemorrhage (ICH) patients who had been administered anti-platelet agents (APA). This retrospective cohort analysis investigated 432 patients (259 men, 60%) who were newly diagnosed with ICH between January 2006 and June 2011 at the tertiary emergency center of Kitasato University Hospital. Median age on arrival was 67.0 years (range, 40-95 years). ICH was subcortical in 72 patients (16.7%), supratentorial in 233 (53.9%), and infratentorial in 133 (30.8%). PLT was performed in 16 patients (3.7%). Within 90 days after admission to the center, 178 patients (41.2%) had died due to ICH. Before the onset of ICH, 66 patients had been prescribed APA because of atherosclerotic diseases. Multivariate regression analysis indicated APA administration was an independent risk factor for death within 7 days (odds ratio, 5.12; Pâ=â0.006) and within 90 days (hazard ratio, 1.87; Pâ=â0.006) after arrival. Regarding the effect of a PLT in ICH patients with APA, no patient with PLT died. PLT had a survival benefit on patients with ICH, according to our analysis. Further prospective analysis is necessary to confirm the effects of PLT on survival in ICH with APA.
Assuntos
Hemorragia Cerebral/terapia , Inibidores da Agregação Plaquetária/farmacologia , Transfusão de Plaquetas/métodos , Idoso , Idoso de 80 Anos ou mais , Hemorragia Cerebral/tratamento farmacológico , Estudos de Coortes , Serviços Médicos de Emergência , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Razão de Chances , Inibidores da Agregação Plaquetária/administração & dosagem , Análise de Regressão , Estudos Retrospectivos , Análise de Sobrevida , Centros de Atenção TerciáriaRESUMO
PURPOSE: Although distraction osteogenesis has been widely accepted to treat craniosynostosis, it occasionally results in wound complications. Positing that they are attributable to the tense pericranium under the scalp, we developed a simple technique to relax the pericranial flap. METHODS: In 12- to 15-month-old infants (mean 13 months), we placed a coronal skin incision and dissected the scalp at the subgaleal layer. Then, we peeled the intact pericranium away from the skull along the planned osteotomy to obtain flaps with pedicles on the caudal part. After osteotomy and setting of the distraction device, the pericranial flaps freed from the scalp flap were repositioned to fit the osteotomy line, dura, and distraction device. The galea and skin were approximated layer by layer. RESULTS: The shape of the skull was successfully corrected, and the bone defect created by expansion was filled by osteogenesis in all patients. During a mean follow-up period of 42.2 months, we encountered no wound complications. CONCLUSIONS: The replaced relaxed pericranium closely adhered to the osteotomy, and the distraction device facilitated vascular growth and bone restoration. Bone resorption was prevented and skin expansion promoted. In patients with iatrogenic dural injury, the pericranium over the injured dura serves as a barrier to prevent cerebrospinal fluid leakage.
Assuntos
Craniossinostoses/cirurgia , Osteogênese por Distração/métodos , Retalhos Cirúrgicos , Humanos , LactenteRESUMO
We investigated whether extremely low frequency (ELF) magnetic field exposure has modification effects on cell survival after ultraviolet B (UV-B) irradiation and on repair process of DNA damage induced by UV-B irradiation in WI38VA13 subcloned 2RA and XP2OS(SV) cells. The ELF magnetic field exposure was conducted using a Helmholtz coil-based system that was designed to generate a sinusoidal magnetic field at 5 mT and 60 Hz. Cell survival was assessed by WST assay after UV-B irradiation at 20-80 J/m(2) , ELF magnetic field exposure for 24 h, followed by incubation for 48 h. DNA damage was assessed by quantification of cyclobutane pyrimidine dimer formation and 6-4 photoproduct formation using ELISA after UV-B irradiation at 20-80 J/m(2) followed by ELF magnetic field exposure for 24 h. No significant changes were observed in cell survival between ELF magnetic field and sham exposures. Similarly, DNA damage induced by UV-B irradiation did not change significantly following ELF magnetic field exposure. Our results suggest that ELF magnetic field exposure at 5 mT does not have modification effect on cell survival after UV-B irradiation and on repair process of DNA damage induced by UV-B irradiation.
Assuntos
Dano ao DNA , Campos Magnéticos , Raios Ultravioleta/efeitos adversos , Linhagem Celular , Sobrevivência Celular/efeitos da radiação , Células Clonais/citologia , Células Clonais/metabolismo , Reparo do DNA/efeitos da radiação , Humanos , Dímeros de Pirimidina/metabolismoRESUMO
A 58-year-old woman with multiple right internal carotid artery (ICA) aneurysms detected incidentally was referred to us. Three-dimensional computed tomography (CT) angiography revealed a broad-necked paraclinoid aneurysm and an aneurysm on the C(1) segment. Aneurysm clipping with preservation of the anterior choroidal artery and posterior communicating artery was not possible because these vessels could not be adequately identified. Intraoperative digital subtraction angiography during obliteration of the cervical portion of the ICA confirmed retrograde flow from the extracranial-intracranial (EC-IC) bypass to the right ophthalmic artery and stagnation of flow in the aneurysms. The cervical portion of the ICA was ligated. Postoperative three-dimensional CT angiography confirmed complete occlusion of both aneurysms and absence of ischemic lesions involving branches of the ICA. Reversal of the blood flow in the ICA via the EC-IC bypass primarily into the ophthalmic artery as the flow outlet by obliterating the cervical portion of the ICA was successful. To prevent ischemia in the territory fed by the perforating arteries of the ICA, tailored flow alteration treatment may be superior to simple parent artery occlusion of the ICA with/without bypass. The pattern of flow alteration should be deliberately based on individual anatomic variations, especially the preservation of flow outlets.
Assuntos
Dissecação da Artéria Carótida Interna/cirurgia , Artéria Carótida Interna/cirurgia , Revascularização Cerebral/métodos , Aneurisma Intracraniano/cirurgia , Procedimentos Cirúrgicos Vasculares/métodos , Artéria Carótida Interna/diagnóstico por imagem , Artéria Carótida Interna/patologia , Dissecação da Artéria Carótida Interna/diagnóstico por imagem , Dissecação da Artéria Carótida Interna/patologia , Revascularização Cerebral/instrumentação , Revascularização Cerebral/normas , Feminino , Humanos , Aneurisma Intracraniano/diagnóstico por imagem , Aneurisma Intracraniano/patologia , Ligadura/métodos , Pessoa de Meia-Idade , Radiografia , Procedimentos Cirúrgicos Vasculares/instrumentação , Procedimentos Cirúrgicos Vasculares/normasRESUMO
OBJECT: The transvenous approach via the inferior petrosal sinus (IPS) is commonly used as the most appropriate for carotid-cavernous fistula (CCF) or cavernous sinus sampling. However, sometimes the IPS is not accessible because of anatomical problems and/or complications, therefore an alternative route is needed. In this paper, the authors present and discuss the utility of a transvenous approach to the cavernous sinus via the inferior petrooccipital vein. METHODS: Four patients, 3 with dural CCFs and the other with Cushing disease, in whom endovascular surgical attempts failed using a conventional venous approach via the IPS, underwent a transvenous approach to the cavernous sinus via the inferior petrooccipital vein (IPOV). One dural CCF case had only cortical venous drainage, the second CCF also mainly drained into the cortical vein with slight inflow into the superior ophthalmic vein and inferior ophthalmic vein, and the third demonstrated drainage into the superior and inferior ophthalmic veins and IPOV. RESULTS: In all cases, the cavernous sinus could be accessed successfully via this route and without complications. CONCLUSIONS: The transvenous approach to the cavernous sinus via the IPOV should be considered as an alternative in cases when use of the IPS is precluded by an anatomical problem and there are no other suitable venous approach routes.
Assuntos
Doenças das Artérias Carótidas/cirurgia , Fístula Carótido-Cavernosa/cirurgia , Seio Cavernoso/cirurgia , Procedimentos Endovasculares/métodos , Procedimentos Neurocirúrgicos/métodos , Osso Occipital/irrigação sanguínea , Osso Petroso/irrigação sanguínea , Idoso , Fístula Carótido-Cavernosa/diagnóstico por imagem , Feminino , Humanos , Masculino , RadiografiaRESUMO
OBJECTIVE: Before treatment for large and giant aneurysms, we need some of the predictors to prognose a good result. In this retrospective study, we attempted to determine criteria such as angiographic signs to identify good candidates for effective endovascular surgery. METHODS: This study involved 45 patients with large or giant aneurysms treated by endovascular embolization. For angiographic study, we delivered a bolus injection of contrast medium. All aneurysms were confirmed angiographically and the morphology was defined in detail before endovascular embolization. We divided the patients into two groups based on angiographic findings. Group A (n=16) manifested stasis of the contrast medium in the aneurysm on venous phase. Group B (n=29) exhibited other findings. We retrospectively evaluated the relationship between stasis of the contrast medium in the aneurysm and results of endovascular embolization. RESULTS AND DISCUSSION: There was no significant difference between the two groups with respect to the size of the aneurysm. However, the neck/dome ratio (P=0·04) and size of the neck (P=0·003) were significantly different between groups A and B. The morphological outcome was better in group A than group B (P=0·03). We demonstrate that contrast stasis is a good predictor of outcome in patients with large or giant aneurysms to consider the endovascular embolization. Hemodynamic studies on large patient populations may reveal other factors predictive of a good treatment outcome.
Assuntos
Artéria Carótida Interna/diagnóstico por imagem , Meios de Contraste/metabolismo , Embolização Terapêutica/métodos , Aneurisma Intracraniano/diagnóstico por imagem , Aneurisma Intracraniano/terapia , Seleção de Pacientes , Adulto , Idoso , Idoso de 80 Anos ou mais , Angiografia Cerebral/métodos , Feminino , Humanos , Aneurisma Intracraniano/metabolismo , Masculino , Pessoa de Meia-Idade , Estudos RetrospectivosRESUMO
It is generally accepted that hemifacial spasm (HFS) is caused by vascular compression at the root exit zone (REZ) of the facial nerve. We saw an HFS patient caused by vascular compression of the distal portion of the facial nerve associated with configuration variation of the facial-vestibulocochlear nerve complex. A 50-year-old female with left HFS was admitted to our hospital. Preoperative magnetic resonance image demonstrated no offending artery around the facial nerve at the nerve's REZ. Microvascular decompression of the left seventh cranial nerve was performed via a lateral suboccipital infrafloccular approach. The facial nerve arose more than 5 mm away from the vestibulocochlear nerve in the brain stem and both traveled apart toward the internal acoustic meatus in the cerebello-pontine cistern. No offending vessel was observed near the REZ of the facial nerve. The abnormal muscle responses of the mentalis muscle disappeared when the AICA was separated from the distal portion of the facial nerve. The patient was completely free of the HFS following surgery. The facial nerve arising away from the vestibulocochlear nerve in the brain stem is rare. It might influence the cause of HFS with compression of the distal portions of the seventh cranial nerve.
Assuntos
Doenças do Nervo Facial/etiologia , Nervo Facial/anormalidades , Espasmo Hemifacial/etiologia , Síndromes de Compressão Nervosa/etiologia , Nervo Vestibulococlear/anormalidades , Animais , Descompressão Cirúrgica , Doenças do Nervo Facial/patologia , Doenças do Nervo Facial/cirurgia , Feminino , Espasmo Hemifacial/patologia , Espasmo Hemifacial/cirurgia , Humanos , Imageamento por Ressonância Magnética , Microcirculação , Pessoa de Meia-Idade , Síndromes de Compressão Nervosa/patologia , Síndromes de Compressão Nervosa/cirurgiaRESUMO
INTRODUCTION: A 2,796-gram male baby was born at 40 weeks gestation by vaginal delivery. Soon after, he was admitted at our department for treatment of a dorsal appendage. RESULTS AND DISCUSSION: Magnetic resonance (MR) imaging showed a low-position spinal cord, skin-covered myelomeningocele, syringomyelia, and a tethered cord. Resection of the caudal appendage and tethering tissue was performed 22 days after birth under electrophysiological monitoring. Histopathological examination of the caudal appendage that was covered with skin revealed the presence of spinal cord tissue and peripheral nerve tissue. The string-like tethering tissue that extended from the spinal cord to the caudalis was a nerve root, and there was fiberization of the caudalis. The syringomyelia was improved at postoperative MR imaging. To our knowledge, there is no report of a similar case in the literature. We report rare combination of myelomeningocele and spinal cord tethering by aberrant nerve root with thoracic syringomyelia.
Assuntos
Meningomielocele/patologia , Radiculopatia/patologia , Medula Espinal/anormalidades , Raízes Nervosas Espinhais/anormalidades , Humanos , Recém-Nascido , Imageamento por Ressonância Magnética , Masculino , Meningomielocele/cirurgia , Fotomicrografia , Radiculopatia/cirurgia , Região Sacrococcígea/anormalidades , Pele/patologia , Medula Espinal/patologia , Medula Espinal/cirurgia , Siringomielia/patologia , Siringomielia/cirurgiaRESUMO
OBJECT: The authors present the difference of shortening the ventricular shunt catheter associated with growth of the cranium between the frontal and parieto-occipital access, a key for long patency of the shunt implanted in children. MATERIALS AND METHOD: Our retrospective study included 28 children. In group A (n=9), the catheter was inserted through a frontal burr hole and in group B (n=19), through a parieto-occipital burr hole. To compare changes that occurred in the interval between the time of insertion and follow-up in the length of the ventricular catheter in the cranium and to assess displacement of the burr used for catheter entry. RESULTS: The results show that ventricular catheter shortening and burr-hole displacement were more pronounced in group A. CONCLUSIONS: This study documents that insertion of the ventricular catheter via the frontal route in children resulted in a higher incidence of shortening due to greater displacement of the burr hole adjacent to the coronal suture. Therefore, we recommend that the parieto-occipital route be used to maintain long-term shunt function.
Assuntos
Cateterismo/métodos , Derivações do Líquido Cefalorraquidiano/métodos , Hidrocefalia/cirurgia , Cateterismo/efeitos adversos , Derivações do Líquido Cefalorraquidiano/efeitos adversos , Derivações do Líquido Cefalorraquidiano/instrumentação , Osso Frontal/diagnóstico por imagem , Osso Frontal/cirurgia , Humanos , Lactente , Recém-Nascido , Osso Occipital/diagnóstico por imagem , Osso Occipital/cirurgia , Osso Parietal/diagnóstico por imagem , Osso Parietal/cirurgia , Próteses e Implantes , Estudos Retrospectivos , Crânio/cirurgia , Técnicas Estereotáxicas , Fatores de Tempo , Tomografia Computadorizada por Raios X , Derivação Ventriculoperitoneal/efeitos adversos , Derivação Ventriculoperitoneal/métodosRESUMO
OBJECTIVE: Intraoperative auditory brainstem response (ABR)-monitoring is useful for hearing preservation in patients undergoing cerebellopontine angle surgery. Prolongation of the latency of wave V, for example, is observed under surgical stress such as cerebellar retraction. We analyzed intraoperative ABR findings to study the neurophysiological mechanism(s) underlying latency prolongation. METHODS: The ABR recorded during microvascular decompression surgery was studied in 18 patients with hemifacial spasm. We measured each trace of the ABR records, both the latency of each wave and some interpeak latencies. We also analyzed their waveforms especially in the early component, to assess changes during surgery. RESULTS: The latency of wave V varied with cerebellar retraction. The delayed latency of wave V was correlated with the prolonged interpeak latency of waves I-III. An additional wave (designated wave I') between waves I and II was appeared; it was accompanied by a prolongation in the latency of wave V. Wave I' contributed to prolongation of the interpeak latency of waves I-III, resulting in a delay in the latency of wave V. Chronological analysis revealed that the minimum latency of wave I' was the same as wave IN, suggesting that wave I' arose near the porus acusticus internus (PAI). CONCLUSION: Our study showed that cerebellar retraction may result in conduction impairment of the auditory nerve near the PAI, suggesting that the Obersteiner-Redlich zone is an electrophysiologically vulnerable site and wave I' is derived from the change in the vector of wave IN. SIGNIFICANCE: Our findings may provide neurophysiological evidence to support the theoretical model of ABR generators by Scherg and von Cramon.
Assuntos
Ângulo Cerebelopontino/cirurgia , Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia , Espasmo Hemifacial/fisiopatologia , Espasmo Hemifacial/cirurgia , Monitorização Intraoperatória , Estimulação Acústica/métodos , Adulto , Idoso , Descompressão Cirúrgica , Eletroencefalografia/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Biológicos , Tempo de Reação/fisiologia , Estudos Retrospectivos , Adulto JovemRESUMO
We studied the acute brain protection provided by an antiplatelet agent, cilostazol, in rat experimental focal ischemia model. We administered 30 mg/kg of cilostazol or vehicle orally 2 hours before transient middle cerebral artery (MCA) occlusion (MCAO) by the intraluminal thread method. We measured the absolute cerebral blood flow (CBF) 2 hours after cilostazol administration, the regional CBF (rCBF) of MCA territory during MCAO, and neurologic deficits and the infarct volume at 22 hours after reperfusion. We found that cilostazol did not increase absolute CBF just before MCAO. rCBF in the MCA territory was reduced to the same degree in both groups up to 60 minutes post-MCAO. A significant increase of rCBF was observed in cilostazol-treated rats at 90 minutes and maintained until reperfusion compared with the controls (P = .031 and P = .047). The average neurologic score and the infarct volume, determined by 2,3,5-triphenyltetrazolium chloride monohydrate staining, were significantly lower in cilostazol-treated rats (P = .010). The single oral administration of cilostazol before transient ischemia in healthy adult rats induced a delayed penumbral CBF increase and resulted in a significant reduction of stroke damage.
Assuntos
Isquemia Encefálica/patologia , Circulação Cerebrovascular/efeitos dos fármacos , Infarto da Artéria Cerebral Média/prevenção & controle , Fármacos Neuroprotetores/farmacologia , Tetrazóis/farmacologia , Administração Oral , Animais , Isquemia Encefálica/complicações , Cilostazol , Infarto da Artéria Cerebral Média/etiologia , Infarto da Artéria Cerebral Média/patologia , Masculino , Fármacos Neuroprotetores/administração & dosagem , Inibidores de Fosfodiesterase/farmacologia , Ratos , Ratos Sprague-Dawley , Fluxo Sanguíneo Regional/efeitos dos fármacos , Tetrazóis/administração & dosagemRESUMO
An alternative technique for cutting the bone flap in supratentorial craniotomy uses a threadwire saw (T-saw), originally developed for spinal surgery. After placing a burr hole at each corner of the intended craniotomy, osteotomy is performed between adjacent burr holes using a craniotome, leaving a bony bridge of approximately 1/3 of the length of the osteotomy. The T-saw is introduced between adjacent burr holes through the epidural space and the bridge is cut with reciprocating strokes. The narrow beveled cut reduces the bone gap for fitted bone flap fixation. On closure, the bridge firmly supports the flap and only sutures are needed for fixation. A minimal amount of filler is required to fill the bone gap. Successful bone flap fixation was obtained in more than 100 cases. No technique-related complications such as dural laceration or flap displacement occurred. Osteotomy using a T-saw was somewhat time-consuming, but cutting efficiency was improved with a Diamond T-saw, featuring a section of cable covered with diamond particles. This method is ideal for bone cuts in cosmetic cranioplasty; is easy and safe to perform, is inexpensive, and avoids the need for flap fixation with metal devices.
Assuntos
Craniotomia/instrumentação , Osteotomia/instrumentação , Adulto , Idoso , Criança , Estudos de Coortes , Craniotomia/métodos , Desenho de Equipamento , Humanos , Masculino , Osteotomia/métodos , Estudos Retrospectivos , Retalhos CirúrgicosRESUMO
This 61-year-old man presented with weakness and sensory disturbance in the legs. There was a spinal dural arteriovenous fistula (SDAVF) fed by the left sixth intercostal artery with dorsal perimedullary drainage. Surgical division of the perimedullary drainage led to rapid neurological improvement. However, on the second postoperative day he experienced transient deterioration of second neuron function in the left upper lumbar segment resulting in motor weakness of the proximal leg muscles, absence of the patellar deep tendon reflex and thigh pain. No radiological findings explaining this deterioration were obtained. He was treated conservatively and all segmental symptoms and signs subsided by the fifth postoperative day. Although the precise mechanisms underlying the dramatic but often reversible deterioration after radical SDAVF treatment remain to be determined, we postulate that this was attributable to postoperative segmental venous hemodynamic changes based on the neurological changes.
Assuntos
Fístula Arteriovenosa/patologia , Fístula Arteriovenosa/cirurgia , Dura-Máter/patologia , Dura-Máter/cirurgia , Complicações Pós-Operatórias/patologia , Coluna Vertebral/patologia , Coluna Vertebral/cirurgia , Hemodinâmica/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Debilidade Muscular/etiologia , Procedimentos NeurocirúrgicosRESUMO
A 32-years-old man with a past history of hemorrhoids presenting with hemiparesis was diagnosed as having sagittal sinus thrombosis with hemorrtagic infarction. Laboratory data revealed macrocytic anemia (Hb 11.2 g/d/) with hypoproteinernia (5.5 g/d). After discharge the patient developed abdominal pain, diarrhea, edema in the leg and sustained anemia. Final diagnosis through colon fiberscope findings was Crohn's disease Macrocytic anemia seemed to be induced by Vit. B12 deficiency due to malabsorption. The mechanism and causal relationship between Crohn's disease and sinus thrombosis is discussed.
Assuntos
Anemia Macrocítica/complicações , Doença de Crohn/complicações , Trombose do Seio Sagital/etiologia , Adulto , Anemia Macrocítica/diagnóstico , Doença de Crohn/diagnóstico , Humanos , Síndromes de Malabsorção/complicações , Masculino , Trombose do Seio Sagital/diagnóstico , Deficiência de Vitamina B 12/complicaçõesRESUMO
BACKGROUND: Endovascular surgery is being increasingly used as an alternative to craniotomy clipping surgery, especially for aged patients and complicated cases. However, tortuous atherosclerotic arteries sometimes interfere with advancement of catheters so that direct puncture may be necessary. Short guiding catheters for use with this approach have been newly developed, as discussed in this article. METHODS: One hundred twenty three anterior circulation aneurysms in 121 patients were consecutively treated by endovascular coil embolization, of which 42 (34%) were older than 70 years. RESULTS: With 21 aneurysms, coil embolization via the transfemoral approach failed, but all could be successfully treated with the direct puncture approach with minor complications such as 1 transient ischemic attack and 1 nonsymptomatic minor leakage. In the aged patients, the direct puncture approach with short guiding catheter resulted in complete obliteration of aneurysms in 20 (71%) of 28 with follow-up angiography. CONCLUSION: Direct puncture using newly developed short guiding catheters is an alternative to femoral approaches for patients with anterior circulation aneurysm with tortuous arteries and obvious atherosclerotic change at bifurcations of the common carotid artery.
Assuntos
Aneurisma Roto/terapia , Angioplastia/instrumentação , Artéria Carótida Primitiva , Embolização Terapêutica/instrumentação , Aneurisma Intracraniano/terapia , Punções/instrumentação , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Desenho de Equipamento , Feminino , Humanos , Pessoa de Meia-Idade , Estudos Retrospectivos , Resultado do TratamentoRESUMO
A 62-year-old man presented with shunt failure manifesting as consciousness disturbance 4 years after placement of a ventriculoperitoneal shunt for subarachnoid hemorrhage. Physical examination found subcutaneous pneumocele around the peritoneal catheter extending from the abdomen to the neck. He had undergone pelvic radiation therapy for bladder cancer 2 years before. The peritoneal catheter was removed from the cervical region, and external ventricular drainage and a descending colon stoma for ileus release were positioned. The cerebrospinal fluid was clear and yielded no cultures. No inflammatory changes were seen. He developed carcinomatous peritonitis and died 4 months later. Retrograde colon gas reflux due to catheter perforation into the colon occluded by metastatic sigmoid cancer was probably the cause. Fragility of the wall of colon associated with the prior abdominal radiation therapy might have been a contributing factor. Subcutaneous pneumocele around the peritoneal catheter, i.e. pneumocele within the fibrous sheath surrounding the catheter, is a differential diagnosis to cerebrospinal fluid collection in patients with subcutaneous swelling around the catheter.
Assuntos
Carcinoma/radioterapia , Colo Descendente/lesões , Colo Descendente/patologia , Neoplasias do Colo Sigmoide/radioterapia , Enfisema Subcutâneo/etiologia , Enfisema Subcutâneo/fisiopatologia , Derivação Ventriculoperitoneal/efeitos adversos , Carcinoma/secundário , Líquido Cefalorraquidiano/microbiologia , Líquido Cefalorraquidiano/fisiologia , Colo Descendente/efeitos da radiação , Transtornos da Consciência/etiologia , Transtornos da Consciência/fisiopatologia , Diagnóstico Diferencial , Evolução Fatal , Humanos , Hidrocefalia/etiologia , Hidrocefalia/fisiopatologia , Hidrocefalia/cirurgia , Obstrução Intestinal/complicações , Obstrução Intestinal/etiologia , Obstrução Intestinal/fisiopatologia , Masculino , Pessoa de Meia-Idade , Monitorização Fisiológica , Peritonite/etiologia , Peritonite/fisiopatologia , Complicações Pós-Operatórias/etiologia , Complicações Pós-Operatórias/fisiopatologia , Complicações Pós-Operatórias/prevenção & controle , Radioterapia/efeitos adversos , Recidiva , Neoplasias do Colo Sigmoide/secundário , Enfisema Subcutâneo/diagnóstico , Tomografia Computadorizada por Raios X , Neoplasias da Bexiga Urinária/patologia , Neoplasias da Bexiga Urinária/radioterapiaRESUMO
This 50-year-old woman presented with headache and visual disturbance. Neuroimaging results demonstrated a well-demarcated tumor attached to the falx cerebri near the transverse sinus, and the lesion was subtotally removed. Based on histological and immunohistochemical evaluation, a solitary fibrous tumor (SFT) was diagnosed. During the next 32 months, the size of the residual tumor increased slightly at the transverse sinus. Stereotactic radiosurgery (SRS) was performed as an adjuvant treatment. Over the course of the next 4 years the tumor decreased in size. The authors suggest that SRS constitutes good adjuvant treatment for regrowing residual SFTs not amenable to reoperation.
Assuntos
Neoplasias Encefálicas/cirurgia , Neoplasias de Tecido Fibroso/cirurgia , Lobo Occipital , Radiocirurgia , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasia ResidualRESUMO
Application of endovascular surgery for very small aneurysms is controversial because of technical difficulties and high complication rates. The aim in the present study was to assess treatment results in a series of such lesions at one institution. Since 1997, endovascular surgery has been advocated for very small ruptured aneurysms (< 3 mm in maximum diameter) that fulfill the criterion of a fundus/neck ratio greater than 1.5. Twenty-one patients were treated, for whom the World Federation of Neurosurgical Societies classification before treatment was Grade I in 10, Grade II in two, Grade III in two, Grade IV in five, and Grade V in two. The aneurysm location was the internal carotid artery in four, the anterior communicating artery in 11, the middle cerebral artery in one, and the vertebrobasilar system in five. In all patients, endovascular surgery was performed using Guglielmi detachable coils after induction of general anesthesia. Initially, the presumed volume of the lesions was calculated for each aneurysm. Thereafter, the appropriate coil length was decided according to the volume embolization ratio, as 30 to 40%. In all attempts to obliterate aneurysms a single coil was used. All aneurysms were completely obliterated as confirmed by postembolization angiography, without procedure-related complications. During the follow-up period only one patient needed additional coil embolization for a growing aneurysm. Final outcomes were good recovery in 15 patients, moderate disability in five, and severe disability in one. Appropriate selection of patients and coils, and use of sophisticated techniques allow a good outcome for patients with very small aneurysms.