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OBJECTIVE: To investigate the comprehensive effects of daily chronic asprosin administration on various pubertal and reproductive parameters in female rats. This study aims to elucidate the role of asprosin in regulating the onset of puberty and its influence on hormonal profiles and ovarian histology. METHODS: Asprosin was administered intraperitoneally (i.p.) at a dose of 500 ng/kg daily for eight weeks. Hormonal assays and histological analyses were performed to evaluate the effects of asprosin on the onset of puberty and reproductive function. RESULTS: Daily chronic administration of asprosin accelerated the onset of the first oestrus. Hormonal assays revealed significant elevations in serum levels of Follicle-Stimulating Hormone (FSH) and Oestradiol (E2), while Inhibin B levels decreased. Histological evaluations demonstrated an increased number of primary and secondary follicles in ovarian tissue, without affecting primordial follicle counts or reproductive organ weights. CONCLUSIONS: Role of adipokines in regulating puberty and reproductive function has increasingly gained recognition. This study aimed to provide the first comprehensive examination of the effects of daily chronic asprosin administration on pubertal and reproductive parameters in female rats. Utilising hormonal assays and histological analyses, asprosin was administered intraperitoneally (i.p.) at a dose of 500 ng/kg, daily, for eight weeks. Our findings revealed that daily chronic administration of asprosin accelerated the onset of the first oestrus. Hormonal assays showed significant elevations in serum levels of Follicle-Stimulating Hormone (FSH) and Oestradiol (E2), while Inhibin B levels decreased. Histological evaluations demonstrated an increased number of primary and secondary follicles in ovarian tissue, without affecting primordial follicle counts or reproductive organ weights. These results provide new insights into asprosin's role in advancing the age of first oestrus and modulating hormonal profiles, thereby offering potential benefits to the female reproductive system.
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Municipal solid waste management is a major concern in developing economies, requiring collective international efforts to achieve carbon neutrality by diverting waste from disposal facilities. This study aims to highlight the importance of the waste sector as it has the potential to significantly contribute to climate change and its toxicity impact on the local ecosystem. Out of the total municipal solid waste generated, only 78 % is collected, either open dumped or thrown in sanitary landfills. The waste sector's ecological impact value is calculated for the Earth's regions, and it is very high at >50 % in Africa, Asia, Latin America and the Caribbean. This sectoral impact value is mainly responsible for greenhouse gas emissions and degradation of the local ecosystem health. Current businessâasâusual practices attribute 3.42 % of global emissions to the waste sector. Various scenarios are developed based on waste diversion and related emissions modelling, and it is found that scenarios 3 and 4 will support the policymakers of the regions in attaining zero carbon footprints in the waste sector. Our findings conclude that cost-effective nature-based solutions will help lowâincome countries reduce emissions from disposal sites and significantly improve the local ecosystem's health. Developed economies have established robust wasteâhandling policies and implementation frameworks, and there is a need for collaboration and knowledge sharing with developing economies at the regional level to sustain the sector globally.
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The solid waste management (SWM) system is in a transitional phase in developing economies, and local municipalities and waste management companies are stepping toward integrating a waste treatment approach in the scheme of waste handling. However, there is an urgent need to explore cost-effective techniques, models, and potential revenue streams to sustain the state-run waste sector self-sufficiently. The proposed SWM model aims to support the local waste sector in Islamabad, the capital city of Pakistan, with 100% service area coverage to attain environmental and economic sustainability by defining dedicated waste collection streams to ensure quality material recovery under a cost-effective approach and modality. The innovative approach is applied to allocate the tonnage to various streams as per the city's current land use plan. The estimated/cost of the cleanliness services will be USD13.1 million per annum with an estimated per ton cost of USD 23. The establishment of the proposed material recovery facility (MRF) will process about 500 t/d of waste to produce 45 t/d compost and recover 130 t/d of recyclables. The environmentally friendly model saves 2.4 million tons of CO2âeq/month from composting and recycling. The average economic potential from MRF and debris-crushing plants, including environmental benefit value, is calculated as USD 3.97 million annually. Recovery of services fee (70%) for various collection streams based on city land use and socio-economic conditions will generate revenue of USD 7.33 million annually. The total revenue will be USD 11.31 million (86% of total annual expenditures) to track the sector's self-sufficiency. To successfully reach the Sustainable Development Goals (SDGs) and Nationally Determined Contributions (NDCs), engaging the private sector from environmentally advanced economies to collaborate in the waste sector to enhance local technical capabilities is recommended.
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Eliminação de Resíduos , Gerenciamento de Resíduos , Resíduos Sólidos , Eliminação de Resíduos/métodos , Análise Custo-Benefício , Gerenciamento de Resíduos/métodos , Reciclagem , CidadesRESUMO
This study was designed to assess the distribution of organochlorines (OCs) in fish species, their spatio-temporal variations, bioaccumulation potential, and associated human health risks via dietary intake. The levels of twenty-three organochlorine pesticides (OCPs) and thirty-five polychlorinated biphenyls (PCBs) were analyzed in six fish species collected from the riverine ecosystem of Punjab Province, Pakistan. The results indicated that the mean levels of Σ23OCPs were 74.1 ng/g ww and 184 ng/g ww, and for Σ35PCBs the levels were 38.8 ng/g ww and 74.8 ng/g ww in herbivorous and carnivorous fish species, respectively. The most abundant contaminants in all fish species were DDTs (65%) and HCHs (14%) among OCPs and heavier PCB congeners (62%) among PCBs. As for dioxin-like PCBs, the WHO toxic equivalency values (ng TEQ/g ww) were in the range of 0.21 (Cyprinus Carpio) to 2.38 (Rita Rita), exceeding the maximum allowable limit of 0.004 ng TEQ/g, ww by the European Commission. Spatio-temporal analysis indicated relatively higher OC levels in winter season with elevated concentrations in fish samples from industrial zone. The bioconcentration factor (L/kg) values ranged from 723 to 2773 for PCBs and 315 to 923 for OCPs in all fish species, with higher levels were reported in carnivorous species. The human health risk assessment at both 50th and 95th percentiles revealed the absence of any significant non-carcinogenic risk as calculated HR was less than 1. However, the critical carcinogenic risk was found to be associated for most of the contaminants, signifying the dietary exposure to OCPs and PCBs might pose the public health concern.
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Carpas , Hidrocarbonetos Clorados , Praguicidas , Bifenilos Policlorados , Animais , Humanos , Bioacumulação , Paquistão , Ecossistema , Carcinógenos , Carcinogênese , Medição de RiscoRESUMO
INTRODUCTION: Asprosin is an adipokine released from white adipose tissue during fasting and acts through the olfactory receptor. It is known that adipokines play roles in reproductive physiology in mammals. However, there are very few studies conducted on role of asprosin in reproductive functions. There are no studies on its relationship with sexual motivation. It was shown in the literature that administration of asprosin to male mice improves olfaction. It is also known that there is a strong correlation between smell and sexual desire. In view of this, it was hypothesized that chronic administration of asprosin would improve olfactory performance and increase sexual incentive motivation in female rats for male partners. METHODS: This hypothesis was tested by applying the hidden cookie test, sexual incentive test, active research test, and sexual behavior test. The changes in serum hormone levels in female rats that chronically received asprosin were also measured and compared. RESULTS: Chronic asprosin exposure increased olfactory performance, male preference ratio, male investigation preference ratio, activity index, and anogenital investigation behavior. Also, serum oxytocin and estradiol levels increased following chronic administration of asprosin in female rats. CONCLUSION: These data suggest that chronic administration of asprosin can result in increased sexual incentive motivation for opposite sex in female rats over increased olfactory performance and changes in reproductive hormones.
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Comportamento Sexual Animal , Olfato , Ratos , Masculino , Camundongos , Feminino , Animais , Olfato/fisiologia , Comportamento Sexual Animal/fisiologia , Ocitocina , Motivação , Jejum , MamíferosRESUMO
The aim of the present study was to determine the occurrence, spatio-temporal variations, source apportioning, and ecological risk assessment of selected PCBs and OCPs in surface water and sediments collected riverine environment of Punjab province, Pakistan. The concentration of ΣOCPs (water: 64-455 ng/L; sediments: 117-616 ng/g) and ΣPCBs (water: 2-132 ng/L; sediments: 3.27-200 ng/g) was found comparatively higher than the levels reported from other parts of the world. The higher concentrations of DDTs and HCHs were detected in both studied matrices, whereas among PCBs, CB-28, 49 and CB-37, 82 were dominant in water and sediments, respectively. The isomeric ratios including α-HCH/γ-HCH, (DDE + DDD) / DDTs, and α /ß-endosulfan reflected the recent use of lindane, technical DDT, and endosulfan in the study area. The WHO-TEQ values of DL-PCBs ranged from 3.6 × 10-6 to 0.115 ng/L and 8.7 × 10-6 to 0.157 ng/g in surface water and sediments in both seasons, respectively. The spatial variation analysis revealed that the sites in the industrial and agricultural zones were highly contaminated. The OCPs and PCBs fluxes to downstream areas were estimated to be 12.4 tons/year and 1.9 tons/year, respectively. The significant ecological risks were estimated to be posed by OCPs and PCBs, as their levels in 67% and 62% of surface water and sediment samples were exceeding the threshold limits, highlighting effects to ecological integrities.
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Hidrocarbonetos Clorados , Praguicidas , Bifenilos Policlorados , Poluentes Químicos da Água , Estações do Ano , Bifenilos Policlorados/análise , Praguicidas/análise , DDT/análise , Paquistão , Ecossistema , Poluentes Químicos da Água/análise , Monitoramento Ambiental , Hidrocarbonetos Clorados/análise , Endossulfano/análise , Medição de Risco , Água/análise , Sedimentos GeológicosRESUMO
This study aims to evaluate municipal landfill sites' operational and financial viability, waste amount and characterization, primary and secondary collection systems, revenue generation from MSW, vehicle routing, and age of landfill sites located in Akhtarabad, Sahiwal Division. Three operational and financial models were developed to calculate cost/ton value based on obtained data. The obtained results indicate that the cost/ton values for models are the following: 20.01 USD for Model-1, 8.96 USD Model-2, and Model-3 is about 10.23 USD. The waste characterization represented waste consisting of compostable (57%), recyclable (10%), Refuse Derived Fuel (RDF) (12%), earth fill (20%), and disposable material (1%). Revenue/ton of municipal solid waste was about 19.47 USD, and according to cost-benefit analysis, the cost of Model-1 was higher than the benefit. In contrast, the costs of Model-2 and Model-3 were found to be lower than the revenue/ton. However, the waste collection efficiency of Model-1 was greater than both remaining models. The study concluded that utilizing all generated waste, only 21% of waste is dumped at the landfill site. It will reduce the area required for landfill sites from 431437 to 90602 m2 for the next 10 years and increase the age of landfill sites by over 20 years. It is recommended that the reuse of municipal solid waste and implementation of the no waste to landfill model would surely save money, land, and fuel, and it will also increase the age of landfill sites.
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Eliminação de Resíduos , Gerenciamento de Resíduos , Eliminação de Resíduos/métodos , Resíduos Sólidos/análise , Cidades , Paquistão , Instalações de Eliminação de Resíduos , Gerenciamento de Resíduos/métodosRESUMO
The purpose of this study was to investigate the effects of treadmill exercise training on obesity-induced behavioral changes in high-fat diet (HFD)-induced male rats. In this study, 40 male Sprague-Dawley rats were divided into 4 groups after they were weaned: Control (C), Exercise (E), Obese (O) and Obese + Exercise (O + E). For the obesity model % 60 high-fat diet were applied. After obesity was induced, rats were either moderate aerobic exercise (treadmill running) trained or left untrained. Different tasks to assess spatial learning and memory (Morris water maze test (MWMT)), depressive-like behavior (forced swimming test(FST), tail suspension test (TST) and anxiety-like behavior (light-dark test (LDT) and open field test (OFT)) were conducted. Exercise caused a significant reduction in duration of immobility in the O group in FST and the decrease in immobility in the O + E rats in TST. The O + E rats demonstrated a significant increase in the time spent in the light box as compared to the O group in the LDT. The O + E rats did not show any behavioral alterations as compared to all the other groups in the OFT. In the O + E group, there was a significant increase in the time spent in the target quadrant compared to the O group in the MWMT. Our results support that treadmill exercise could improve cognitive, depressive-like, anxiety-like behavioral changes in the HFD-induced obese rats.
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Ansiedade , Dieta Hiperlipídica , Ratos , Animais , Masculino , Dieta Hiperlipídica/efeitos adversos , Ratos Sprague-Dawley , Ansiedade/etiologia , Ansiedade/terapia , Ansiedade/psicologia , Obesidade/terapia , Obesidade/psicologia , Exercício FísicoRESUMO
The electronic waste generation rate is increasing drastically at a rate of 3 to 5% per year in developing countries. The aim of this study is to analyze the environmental sustainability and economic benefits of such e-waste management in the developing economies like Pakistan. The life cycle assessment (LCA) method has been employed for streamlined impact analysis of the end-of-life processing of e-waste focusing mainly on laptop computers and liquid crystal display (LCD) desktop computers in Pakistan. The method of cumulative exergy extraction from the natural environment (CEENE) has also been deployed for the relative assessment of resources' consumption of e-waste recycling versus landfilling scenario. The determined impact scores are 1.79E + 03 kg CO2 eq., 7.19E-07 kg CFC-11 eq., 1.02E + 03 kg 1,4-DCB, 7.13E + 01 kg 1,4-DCB, and 3.41E-03 kg Cu eq. in climate change potential, stratospheric ozone depletion, ecotoxicity potential, human noncarcinogenic potential, and mineral resource depletion impact categories, respectively. The results of CEENE analysis reveal that approximately 80% of the impact on natural resources is reduced by the efficient recycling of e-waste. The comparative assessment of respective scores for current and target material weight recovery (MWR) indicators represented that by increasing the MWR indicator by 33.8% for laptop computers and by 27.2% for LCD computers, the country will achieve an annual economic benefit of US $191.56 million. This is greatly significant for a transitional shift towards e-waste revalorization while realizing the objectives of sustainable resource consumption. Innovative improvement measures ensuring economically feasible, energy-efficient, and environment friendly waste collection, treatment, and recycling practices present an invaluable opportunity for developing countries.
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Resíduo Eletrônico , Eliminação de Resíduos , Gerenciamento de Resíduos , Países em Desenvolvimento , Humanos , Paquistão , Reciclagem/métodos , Gerenciamento de Resíduos/métodosRESUMO
This study aims to investigate the decolourization efficiency of reactive black 5 (RB-5) dye by using CuMn2O4/gC3N4 coated zeolites (zeolite 4A) for the first time in a hybrid electro-flocculation-catalytic ozonation process. A comparison between various treatment options such as electro-flocculation, electro-flocculation in the presence of a catalyst, and catalytic ozonation in combination with electro-flocculation was explored. Moreover, the effect of different factors such as pH, time, catalyst dose, ozone dose, radical scavenger, and voltage has been studied in each treatment option mentioned earlier. The results indicated that the best treatment option was found to be catalytic ozonation in combination with electro-flocculation with removal efficiency (RE) of 90.31% at pH 10 after 30 min of the treatment process. The hydroxyl radical scavenger effect indicated that the synergistic catalytic process follows a radical mechanism. It is therefore concluded that CuMn2O4/gC3N4-zeolite catalysts in synergic electro-flocculation-catalytic ozonation process may be effectively used for the treatment of textile wastewaters.
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Ozônio , Poluentes Químicos da Água , Purificação da Água , Zeolitas , Catálise , Floculação , Naftalenossulfonatos , Poluentes Químicos da Água/análiseRESUMO
A multi-elemental analysis, including heavy metals and trace elements in ambient air samples, was conducted for computers, wires, lead batteries, and iron extraction facilities in Lahore by proton-induced X-ray emission (PIXE) spectroscopy. The data obtained from PIXE analysis revealed the presence of Mg, Al, Zn, S, Pb, K, Ti, Fe, Si, K, and Cr elements at e-waste recycling facilities. The computer dismantling site revealed a higher concentration of Fe (634.7 µg/m3), Al (176.8 µg/m3), Pb (135.4 µg/m3) and Zn (122.5 µg/m3) in the air samples. The decreasing order of heavy metals and trace elements contribution at the computer dismantling site was as Si > Fe > Al > Pb > Zn > Mg > Ca > Cr > K > S > Ti. Similarly, at wires/cables burning site, a higher concentration of Fe, Al, and Pb (829.8 µg/m3, 184.5 µg/m3 and 115.6 µg/m3, respectively) were observed, and the elements revealed a descending trend as Si > Fe > Al > Zn > Pb > Mg > Ca > Cr > Ti > K > S. The lead batteries dismantling site showed the highest Pb concentration (141.2 µg/m3) due to the disassembling of lead acid batteries. Al, Zn, Fe, and Cr also revealed higher concentration in air samples and exhibited a declining trend as Si > Fe > Al > Pb > Zn > Cr > Ca > Mg > Ti > K > S. However, the highest concentration of Fe (865.7 µg/m3) was detected in air samples of iron extraction sites besides Al and Zn. The descending order of trace elements contribution was Si > Fe > Al > Zn > Mg > K > Ca > Ti > S. Furthermore, the correlation between workers' awareness and their possible health impacts were also examined in the study. Most of the workers were less aware of the hazardous impacts. Majority of workers and residents were suffering from a respiratory illness (27.5% and 32.5%), kidney failure (15% and 22.5%), and neurological disorders (15% and 7.5%), respectively, due to exposure of airborne particulate matter which could be correlated with the higher concentration of heavy metals such as Pb, Cr, Zn, and Fe in the ambient air at the e-waste recycling sites.
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Poluentes Atmosféricos , Metais Pesados , Oligoelementos , Poluentes Atmosféricos/análise , Cromo , Monitoramento Ambiental , Humanos , Metais Pesados/análise , Material Particulado/análise , Reciclagem , Oligoelementos/análiseRESUMO
The study was carried out to identify the potential of phytoremediation within a flowing drain through Eichhornia crassipes in combination with two bacillus species to treat the inorganic and polycyclic aromatic hydrocarbons (PAHs) from industrial effluent at Kala Shah Kaku (KSK), Lahore, Pakistan. Results showed that the highest metals removal efficiency was found in Cr, Pb, Ni, and Cu as 72.4, 83.3, 82.35, and 63.63%, respectively. However, biochemical oxygen demand (BOD) and chemical oxygen demand (COD) removal efficiencies were also considerably higher (66.66 and 66.67%). The BOD, COD, sulfates, phosphate, and total dissolved solids (TDS) showed a higher reduction rate as 1442.7, 1967.3, 1148.2, 7225.4, and 911.5 g m-2 d-1, respectively. Chlorophyll a + b and carotenoid contents were decreased from 7.92 to 5.78 mg kg-1, 3.03 to 3.01 mg kg-1, respectively and total nitrogen was increased from 22 to 27 mg kg-1 in E. crassipes. Bio-concentration factor was higher for all metals and the maximum was found in Cr (<1). The reduction efficiency of Æ©PAHs was found up to 60% with different rings structure. The use of Bacillus safensis strain showed the higher percentage reduction for BOD, nitrates, sulfates, and phosphates. The Study provide practical reference for bacterial assisted phytoremediation of urban drain.
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Eichhornia , Poluentes Ambientais , Poluentes Químicos da Água , Bacillus , Bactérias , Biodegradação Ambiental , Clorofila A , Paquistão , Esgotos , Águas Residuárias/análise , Poluentes Químicos da Água/análiseRESUMO
Toxic elemental exposure through consumption of contaminated crops is becoming a serious concern for human health. Present study is based on the environment and health risk assessment of wastewater irrigated soil and crops in a semi-arid region Faisalabad, Pakistan. The concentrations of potentially toxic elements (Cu, Cr, Mn, Fe, Pb, Zn, Ni) were analysed by atomic absorption spectrometer in five different crops (Corn, rice, wheat, sugarcane and millet), while, their topsoil's and multi targeted risks analysis were assessed. Results showed, the mean values of Pb and Zn were higher in crop than Food and Agriculture Organization guidelines for food additives and contaminants. A strong positive correlation was found among wastewater and crop's toxic metals (r2 values in Cu, Zn, Pb, Ni and Cr were 0.913, 0.804, 0.752, 0.694, 0.587 respectively). Whereas, a strong correlation was also found among soil and wastewater lead (r2 = 0.639). The calculations of Nemerow Integrated Pollution Index (NIPI) showed the soil samples maximum pollution limit (NIPI > 3) and Potential Ecological Risk Index (PERI) was found to be higher than maximum limit (PERI > 600) for all samples. While, for non-carcinogenic risk, Hazard Index (HI) values in adult were near threshold (HI > 1) for all crop samples. In children, the HI values for Corn, Rice and Wheat were above threshold limit and for Sugarcane and Millet, these were near to threshold. Cancer risk values for Cr found higher than safe limit (1 × 10-6) in adult and children for crop samples. Crop irrigation by wastewater irrigation is a prominent alternative option for water scarce countries, however prior testing and treatment of such wastewater streams must be employed to minimize the adverse impacts on human health and environment.
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Till date no medication or vaccine is available to cope with the COVID-19 infection and infection rate is increasing drastically across the globe. Only preventive measures and healthy life style with efficient immune system have been suggested by WHO to fight and stay safe from COVID-19. WHO recommended alcohol based hand sanitizers for frequent hand hygiene, which are mainly made up from ethanol, isopropyl alcohols, hydrogen peroxides in different combinations. These preparations may become toxic to human health and environment when misused. These chemicals have known toxic and hazardous impact on environment when released by evaporation. In early five months of 2020, American Association of Poison Control Center reported 9504 alcoholic hand sanitizer exposure cases in children under the age of 12 years and recognized that even a small amount of alcohol can cause alcohol poisoning in children that is responsible for confusion, vomiting and drowsiness, and in severe cases, respiratory arrest and death. Furthermore, frequent usage of said hand sanitizers has reported increased chance of antimicrobial resistance and chance of other viral diseases. Current review is designed with main objective to highlight the toxic and serious health risks to human health and environment by frequent using hand hygiene products with alcohols based formulations.
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Infecções por Coronavirus , Higienizadores de Mão , Pandemias , Pneumonia Viral , Betacoronavirus , COVID-19 , Criança , Desinfecção das Mãos , Humanos , SARS-CoV-2 , Estados UnidosRESUMO
In this study, the multi-attribute utility theory model, one of the most widely utilized multi-criteria decision-making methods, is employed to analyze the relative sustainability and cleaner development mechanism (CDM) potential of a novel bioenergy project in Pakistan and four registered CDM bioenergy installations in China, India, Sri Lanka, and Thailand. Four major sustainability evaluation criteria selected for the study are technology, economy, environment, and social aspects, whereas "simple multi-attribute rating technique" (SMART) and "additive synthesis method" were utilized for the calculation of weighting factors. The most significant indicator was emission reduction, and least significant indicator was job creation with 24% and 15% respective weightages, in the sustainability scoring. Moreover, for three considered evaluation scenarios, (I) base case, (II) per kilowatt, and (III) per kilowatt hour, the bioenergy project in Pakistan has the highest comparative sustainability values of 0.735, 0.592, and 0.492 respectively. This analysis will provide an insight assistance to developing countries for establishing sustainable energy installations under CDM.
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Conservação dos Recursos Naturais , China , Índia , Paquistão , Sri Lanka , TailândiaRESUMO
Phytoremediation is a cost-effective and eco-friendly process to remove heavy metals from water. A small-scale experiment was conducted to determine the phytoremediation efficiency of two macrophytes, i.e. Pistia stratiotes and Eichhornia crassipes for the removal of chromium and copper from the prepared metal solutions of different concentrations (2, 4, 6, 8â mg/L) for a period of one month. Both aquatic macrophytes showed different efficiency for the removal and accumulation of Chromium (Cr) and Copper (Cu). The dry biomass of both macrophytes increased over the period of time. The average accumulation of chromium in roots and leaves of P. stratiotes was 85â mg, 56â mg and copper was 96â mg and 70â mg, respectively whereas the average accumulation of chromium in roots and leaves of E. crassipes was 90â mg, 53â mg and copper was 86â mg, 50â mg, respectively. Higher absorbance of metals was observed in roots as compared to the leaves of both macrophytes. The concentration of metals in the solution significantly decreased from day 1 to day 30. The results of one-way ANOVA showed that removal of Cr was significantly (p < .05) greater in E. crassipes and removal of Cu was significantly (p < .05) greater in P. stratiotes.
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Araceae , Eichhornia , Poluentes Químicos da Água , Biodegradação Ambiental , Cromo , CobreRESUMO
In this study, the heat vulnerability index has been developed for a megacity Lahore. Although Pakistan stands at 12th rank among highly exposed countries to climate change, very little research has been dedicated in exploring the heat-related vulnerability of exposed populations. We have applied the principal component analysis with varimax rotation on well-established indicators of exposure, sensitivity, and adaptive capacity to determine the heat vulnerability. This study has resulted in two principal components sharing 70.4% variance. Principal component 1 comprises pre-existing illness, population density, housing density, education, and normalized difference vegetation index with following significant (> 0.4) loading values 0.91, 0.91, 0.91, 0.57, and - 0.773, respectively, and principal component 2 combines the nature of housing material (0.964) followed by the water availability (0.962) and minority status (0.539). The hot spot analysis and overlay analysis have also been applied on the extracted component, and the resultant co-occurrence of high variable class, high vulnerability, and hot spots of vulnerability helped to grip those areas which imperatively require the applications of heat-related health interventions. The heat vulnerability index developed in our study clarifies that the most vulnerable populations are confined in the central vicinities of Lahore and less vulnerable are those which inhibit towards the outskirts of the city.
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Mudança Climática , Temperatura Alta , Cidades , Humanos , Paquistão , Populações VulneráveisRESUMO
A novel medium-large industrial-scale, anaerobic digestion (AD) waste-to-energy pilot plant has been investigated in terms of cost-benefit, environmental impact, and economic sustainability. This pilot plant exclusively features a multi-digester AD system induced by motorized stirring, methane purification, compression, storage and digestate-fertilizer processing systems, and subsequent electricity generation. The operational productivity and success of the pilot plant has been proven on a variety of waste feedstock substrates in the form of cow-buffalo manure and potato waste. The plant has an average energy productivity of 384 kWh/day and an annual rate of return was estimated to be 15.4%. The life cycle environmental impact analysis deliberated the significant impact potentials in terms of climate change (kg CO2 equivalent), and fossil depletion (kg of oil equivalent) for three selected substrates: 100% cow-buffalo manure (CBM), 100% potato waste (PW), and a mixture of 75% CBM and 25% PW. The results show the climate change potential of 70 kg, 71 kg, and 149 kg and fossil depletion potential of - 2.43 kg, - 16.45 kg, and 18 kg per 2000 kg of substrate slurry, respectively. As such, the substrate of 100% CBM posed the least climate change impacts whereas 100% PW has been established most effective under the fossil depletion category.
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Fertilizantes , Gerenciamento de Resíduos/economia , Gerenciamento de Resíduos/métodos , Anaerobiose , Animais , Biocombustíveis , Dióxido de Carbono/análise , Dióxido de Carbono/metabolismo , Bovinos , Análise Custo-Benefício , Meio Ambiente , Eutrofização , Esterco , Metano/metabolismo , Paquistão , Energia Renovável , Solanum tuberosumRESUMO
Urban areas under the influence of multi-industrial activities with arid and semi-arid environments witness the significant increase in environmental pollution especially in the water sector. The present study evaluated the water quality and associated health risk assessment through heavy metal pollution. Drinking (n = 48) and surface (n = 37) water samples were collected from semi-arid multi-industrial metropolis, Faisalabad, Pakistan. Physio-chemical and biological parameters and different metals (Al, As, Ba, Cd, Cr, Cu, Fe, Pb, Ni and Zn) were investigated using standard procedures and multivariate water quality assessments. Many physio-chemical and biological parameters and metals especially arsenic were exceeding the permissible limit of Punjab environmental quality standards and the World Health Organization. The results from water quality index showed that < 56% samples have poor, < 8% have very poor and < 6% have unsuitable water quality for drinking purposes. Water quality for the Gugera Branch Canal was found suitable with medium sodium (alkalinity) and salinity hazards, while it was found poor with magnesium absorption ratio. Hazard quotient (HQ) values for arsenic were found at the threshold level (HQ > 1) and carcinogenicity was found in case of arsenic and chromium (1 × 10-4) in adults and children. Semi-arid weather combined with different anthropogenic activities and unusual water features provoked metal contamination. Results of the present study can deliver basic information for effective management of water in the most populous and industrial areas.
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Medição de Risco/métodos , Poluentes Químicos da Água/análise , Qualidade da Água , Adulto , Arsênio/análise , Arsênio/toxicidade , Carcinógenos/análise , Carcinógenos/toxicidade , Criança , Cidades , Exposição Dietética/efeitos adversos , Água Potável , Água Doce/análise , Humanos , Indústrias , Metais Pesados/análise , Metais Pesados/toxicidade , Paquistão , Poluentes Químicos da Água/toxicidadeRESUMO
The correct image of Figure 4 is shown in this paper. The original article has been corrected. Fig. 4: Scree plot of heavy metals in sediments. The graph shown in upper right corner shows the concentration of principle components variables in a loading plot.