Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros








Base de dados
Intervalo de ano de publicação
1.
Org Biomol Chem ; 4(23): 4336-44, 2006 Dec 07.
Artigo em Inglês | MEDLINE | ID: mdl-17102879

RESUMO

Endoergic electron transport across vesicle bilayers from ascorbate (Asc-) in the inner waterpool to methylviologen (MV2+) in the outer aqueous solution was driven by the irradiation of pyrene derivatives embedded in the vesicle bilayers. The initial rate of MV2+ reduction is dependent on the substituent group of the pyrenyl ring; a hydrophilic functional group linked with the pyrenyl ring by a short methylene chain acts as a sensitizer for the electron transport. Mechanistic studies using (1-pyrenyl)alkanoic acids (1a-c) as sensitizers suggest that the electron transport is mainly initiated by the reductive quenching of the singlet excited state of the pyrene by Asc- and proceeds by a mechanism involving electron exchange between the pyrenes located at the inner and outer interface across the vesicle bilayer. We designed and synthesized novel unsymmetrically substituted pyrenes having both a hydrophilic group linked by a short methylene chain and a hydrophobic long alkyl group (5a-c), which acted as excellent sensitizers for the electron transport across vesicle bilayers.


Assuntos
Transporte de Elétrons , Bicamadas Lipídicas/química , Pirenos/química , Ácido Ascórbico/química , Fluorescência , Cinética , Luz , Bicamadas Lipídicas/efeitos da radiação , Ressonância Magnética Nuclear Biomolecular , Paraquat/química , Fotoquímica , Fármacos Fotossensibilizantes , Espalhamento de Radiação
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA