1.
Org Lett
; 25(43): 7858-7862, 2023 Nov 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37862138
RESUMO
A cobalt(II)-catalyzed coupling-cyclization cascade reaction between tryptamine-derived isocyanides and iodonium ylides is investigated, which allowed for the synthesis of different types of spiroindoline compounds by variation of substituents at the N1- and C2-positions in the indole skeleton. More interesting is that the spiroindoline products could undergo despirocyclization in the presence of amines, enabling efficient construction of enamine compounds.