Assuntos
Neurônios Motores/efeitos dos fármacos , Contração Muscular/efeitos dos fármacos , Músculo Esquelético/inervação , Tolperisona/farmacologia , Administração Oral , Relação Dose-Resposta a Droga , Eletromiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neurônios Motores/fisiologia , Relaxantes Musculares Centrais/farmacologia , Músculo Esquelético/efeitos dos fármacos , Valores de ReferênciaRESUMO
A clinical experiment on a group of 22 patients, aged 45,4+/-6,2 years, with compression radiculopathies L(5)-S(1) has proved the possibility of optimized therapeutic electrostimulation of peripheral nerves under the control of F-waves on ENMG. Parameters of electrostimulation were specified as follows: rectangular impulses of positive polarity and duration of 500-1000 ms, frequency 1-10 Hz and submaximal intensity of current. The positive effect of electrostimulation on the conductivity of nerve fibers and excitability of spinal motor neurons was found.
Assuntos
Deslocamento do Disco Intervertebral/complicações , Vértebras Lombares , Radiculopatia/terapia , Estimulação Elétrica Nervosa Transcutânea/métodos , Eletromiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neurônios Motores/fisiologia , Condução Nervosa/fisiologia , Radiculopatia/etiologia , Radiculopatia/fisiopatologia , Resultado do TratamentoRESUMO
Efficacy and safety of movalis (meloxicam) injected into trigger points of 94 patients with vertebrogenic lumbago-ischialgia syndrome have been assessed. Patients have been stratified into 3 randomized groups: the first group received 3 injections of movalis into trigger points with the following administration of tablets (15 mg per day); 2nd group received - 3 intramuscular injection movalis with the following administration of tablets (15 mg per day); 3nd - was control. Treatment efficacy has been assessed with the Visual-Analogous scale, a five-point scale for assessment of vertebroneurological symptoms, the Oswestry Disability Index, the McGill Pain Questionnaire, stimulating ENMG. Patients treated with movalis injections into trigger points and intramuscular had no local side-effects. The analgesic effect was more pronounced after three injections into trigger points compared to the intramuscular injection. The efficacy of treatment was the highest in the first group (75,6%) comparing to the 2nd (64,3%) and the 3rd (33,3%) ones.
Assuntos
Anti-Inflamatórios não Esteroides/uso terapêutico , Dor Lombar/tratamento farmacológico , Tiazinas/uso terapêutico , Tiazóis/uso terapêutico , Anti-Inflamatórios não Esteroides/administração & dosagem , Anti-Inflamatórios não Esteroides/efeitos adversos , Humanos , Injeções Intramusculares , Meloxicam , Tiazinas/administração & dosagem , Tiazinas/efeitos adversos , Tiazóis/administração & dosagem , Tiazóis/efeitos adversos , Resultado do TratamentoRESUMO
A randomized double-blind study of the efficacy of midocalm combined with tractional therapy has been carried out in 24 patients (indexed group) comparing to the tractional therapy without midocalm (the drug has been substituted with placebo) in 25 patients (comparison group). The effective number of injections was 3-6 in the indexed group and 7 in the comparison group. A quantitative assessment revealed that in the indexed group treatment efficacy was 1,56 times higher and the effect achieved sooner than in the comparison group.