[The effect of prokinetic treatment and eradication of Helicobacter pylori on gastric emptying and symptoms of functional dyspepsia]. / Wplyw leczenia prokinetycznego i eradykacji Helicobacter pylori na opróznianie zoladka i objawy dyspepsji czynnosciowej.

UNLABELLED: The aim of the study was to estimate clinical symptoms and gastric emptying in functional dyspepsia (f.d.) before and after treatment. METHODS: 40 patients were examined. Control group consisted of 10 healthy volunteers. The severity of symptoms was estimated in 0-3 score. Gastric emptying was measured with radionuclide method. Examinations were performed prior and after treatment with famotidine (group I), cisaprid + famotidine (group II), cisaprid (group III), eradication of H.p. (group IV). RESULTS: Significantly delayed gastric emptying was observed in patients with f.d. Severity of symptoms score was significantly reduced after treatment, and was: group. I 13.8-11.2, group II. 14.8-8.8, group III 13.7-6.9, group IV 13.3-9.0. Gastric emptying was improved after treatment in groups: II 64.3-45.5 and III 65.1-46.7 respectively. In groups I and IV there was a minor nonsignificant change in gastric emptying. CONCLUSIONS: 1. Gastric emptying is significantly delayed in patients with f.d. 2. Prokinetic therapy with cisapride results in the improvement of gastric emptying together with alleviation of clinical symptoms of f.d. 3. Antisecretory treatment with famotidine and eradication of Helicobacter pylori do not effect gastric emptying, but exerts positive clinical response.

[The applicability of phleboscintigraphy in diagnosis and treatment result evaluation of patients with disorders of leg venous circulation]. / Przydatnosc fleboscyntygrafii w diagnostyce i ocenie wyników leczenia chorób ukladu zylnego konczyn dolnych.

The aim of the paper was the applicability of phleboscintigraphy in the diagnosis and monitoring of the treatment in patients with various disorders of venous circulation in lower extremities. The study comprised eighty-eight patients with the suspicion of deep veins impatience. The examination was performed using DTPA 99mTc by means of a gamma camera connected with a computer. The radioisotope was injected into the foot dorsal veins. The dose was 185 MBq. Its activity was monitoring continuously for 1 min. The estimation of the results was performed by scintigraphy imaging and curves of activity changes of chosen regions over deep veins. Phleboscintigraphy was found out to be of a great value in the diagnostics and assessment of treatment results in thrombotic-embolic disease, extra-thrombotic syndromes and in qualification of patients with lower legs varices for surgical procedures. Because of easy performance, possibility of repeating, small invasiveness and rather low cost, the method can be recommended as an introductory examination in patients with above mentioned diseases.

Relation between mean ventricular phases in chronic cor pulmonale measured by radionuclide ventriculography.

ECG-gated equilibrium radionuclide ventriculography was performed in 17 patients with pulmonary heart disease (Cp) and in 11 healthy subjects (Nm). Fourier analysis was applied to the time activity curve in each pixel, and the phase and amplitude of the basic frequency were computed. From the pixel-by-pixel values, the mean phase of each ventricle was calculated. It was found that the difference between mean phase of right and left ventricle (psi(R-L)] was significantly greater in Cp (+13.8 degrees +/- 7.8 degrees) than in Nm (-0.3 degrees +/- 3.9 degrees). This difference was almost twice as great in Cp with RV failure (+15.9 degrees +/- 7.8 degrees) than in those without it (+8.8 degrees +/- 5.1 degrees). Abnormally increased psi(R-L) values were detected in about 70% of patients with Cp. Interventricular phase difference had a weak positive correlation with the amplitude of S wave in lead I of the ECG (r = 0.533). It is concluded that in most patients with Cp the phase of the RV contraction is delayed and that this delay may be connected with deterioration of RV performance.