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1.
Behav Sci (Basel) ; 14(2)2024 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-38392457

RESUMO

This study focused on the nuanced phenomenon of gendered parenting by exploring how maternal son preference is associated with depressive symptoms among Chinese early adolescents. Focusing on 1093 junior high school students from a relatively affluent city in Western China, this study examined the mediating roles of mother-child attachment and father-child attachment as well as the moderating role of school connectedness in the relationship between maternal son preference and depressive symptoms. The results revealed a noteworthy positive correlation between maternal son preference and depressive symptoms among female adolescents, with no significant association observed in males. In addition, mother-child attachment and father-child attachment mediated the relationship between maternal son preference and girls' depressive symptoms, supporting the "spillover effect" and "crossover effect". Moreover, a moderation effect analysis indicated that a higher level of school connectedness can buffer the effect of maternal son preference on girls' depressive symptoms, while a lower level of school connectedness can enhance the effect of maternal son preference on girls' depressive symptoms. In addition, maternal son preference was negatively correlated with boys' depressive symptoms in relation to high school connectedness. These insights help enhance people's understanding of gendered parenting, emphasizing the enduring necessity of addressing son preference within the broader context of promoting gender equality.

2.
BMC Cancer ; 24(1): 193, 2024 Feb 12.
Artigo em Inglês | MEDLINE | ID: mdl-38347528

RESUMO

BACKGROUND: Prognosis prediction for pancreatic cancer has always been difficult in clinical practice because of its high heterogeneity and mortality. The aim of the study was to assess the value of prognostic immune-inflammatory-nutritional (PIIN) score on overall survival (OS) in postoperative patients with pancreatic cancer and to develop a nomogram incorporating PIIN score. METHODS: This study retrospectively analyzed the clinic pathological data of 155 patients with pancreatic cancer who underwent radical surgery. PIIN score was calculated by measuring the fibrinogen (FIB), neutrophil to lymphocyte ratio (NLR), systemic immune-inflammation index (SII), albumin-bilirubin (ALBI) score, and prognostic nutritional index (PNI). Patients were divided into two groups by PIIN score levels over a threshold of 37.2. Univariate and multivariate analysis were performed using the Cox regression analysis model. The time-dependent receiver operating characteristic (ROC) curve was plotted to compare the prognostic values of the scoring systems. Finally, a nomogram based on PIIN score was constructed and validated. RESULTS: Multivariate regression analysis showed that PIIN score (hazard ratio (HR) = 2.171, 95% confidence interval (CI) = 1.207-3.906, P = 0.010), lymphovascular invasion (HR = 1.663, 95% CI = 1.081-2.557, P = 0.021), poor tumor grade (HR = 2.577, 95% CI = 1.668-3.982, P < 0.001), bad TNM stage (I vs. II: HR = 1.791, 95% CI = 1.103-2.906, P = 0.018; I vs. III: HR = 4.313, 95% CI = 2.365-7.865, P < 0.001) and without adjuvant chemotherapy (HR = 0.552, 95% CI = 0.368-0.829, P = 0.004) were independent risk factors for OS. The time-dependent ROC curves revealed that PIIN score was better than the other scoring systems in predicting survival prognosis. And last, the nomogram established from independent factors such as PIIN score had good predictive power for OS. The ROC curve results showed that the AUC values for 1, 3 and 5 years were 0.826, 0.798 and 0.846, respectively. The calibration plots showed the superior clinical applicability of the nomogram. CONCLUSION: The nomogram model based on PIIN score can be utilized as one of the prognosis stratifications as well as postoperative follow-up for the development of individual treatment for pancreatic cancer.


Assuntos
Nomogramas , Neoplasias Pancreáticas , Humanos , Estudos Retrospectivos , Prognóstico , Fatores de Risco , Neoplasias Pancreáticas/cirurgia
3.
World J Surg Oncol ; 21(1): 303, 2023 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-37743468

RESUMO

PURPOSE: The Naples prognostic score (NPS) is a comprehensive prognostic model that includes inflammatory and nutrition-related indicators and is increasingly used as a prognostic score for various malignant tumors. Given its predictive effect on prognosis in patients with gallbladder cancer, it is currently unclear. This study aimed to investigate the role of preoperative NPS in predicting prognosis in gallbladder cancer surgery patients. PATIENTS AND METHODS: A retrospective analysis was performed for 135 patients who underwent radical surgery for gallbladder cancer without preoperative treatment between March 2011 and January 2020. NPS was calculated by measuring the preoperative total cholesterol value, serum albumin value, neutrophil-lymphocyte ratio (NLR), and lymphocyte-monocyte ratio (LMR). They were then divided into 3 groups (groups 0, 1, and 2) based on NPS scores. Survival analysis was performed using the Kaplan-Meier method and log-rank test. Univariate and multivariate Cox proportional hazards models were used to identify independent prognostic factors. Plot time-dependent receiver operating characteristic (ROC) curves to compare the prognostic value of scoring systems. Finally, a nomogram model was developed with independent prognostic factors. RESULTS: Multivariate analysis showed that NPS was an independent risk factor affecting OS (HR = 3.417, p < 0.05). The time-dependent ROC curve results showed that NPS had a better predictive value on survival prognosis than other indicators. The nomogram constructed according to independent factors such as NPS has a good predictive ability for OS. CONCLUSION: As a simple and reliable tool, the NPS has important predictive value in the survival prognosis of gallbladder cancer patients. The nomogram model constructed by NPS will help determine prognosis and make individualized treatment decisions.


Assuntos
Carcinoma in Situ , Neoplasias da Vesícula Biliar , Humanos , Prognóstico , Neoplasias da Vesícula Biliar/diagnóstico , Neoplasias da Vesícula Biliar/cirurgia , Estudos Retrospectivos , Nomogramas
4.
BMC Surg ; 23(1): 260, 2023 Aug 30.
Artigo em Inglês | MEDLINE | ID: mdl-37649027

RESUMO

BACKGROUND: This study aimed to investigate the risk factors for 30-day mortality in patients with malignant biliary obstruction (MBO) after endoscopic retrograde cholangiopancreatography (ERCP) with endobiliary metal stent placement. Furthermore, we aimed to construct and visualize a prediction model based on LASSO-logistic regression. METHODS: Data were collected from 245 patients who underwent their first ERCP with endobiliary metal stent placement for unresectable MBO between June 1, 2013, and August 31, 2021. Univariable and multivariable logistic regression analyses were conducted to identify the risk factors for 30-day mortality. We subsequently developed a logistic regression model that incorporated multiple parameters identified by LASSO regression. The model was visualized and the nomogram was plotted. Risk stratification was performed based on nomogram-derived scores. RESULTS: The 30-day mortality rate was 10.7% (23/245 patients). Distant metastasis, total bilirubin, post-ERCP complications, and successful drainage were independent risk factors of 30-day mortality. The variables screened by LASSO regression, including distant metastasis, total bilirubin, post-ERCP complications, and successful drainage, were incorporated into the logistic model. The results were visualized through a nomogram based on the model. To assess the model's performance, discrimination was evaluated using the area-under-the-curve values obtained from receiver operating characteristic analyses with 10-fold cross-validation in the training group and validated in the testing group. The calibration curve showed the good predictive ability of the model. Decision curve analysis is used to evaluate the clinical application of nomogram. Finally, we performed risk stratification based on the risk calculated using the nomogram. Patients were assigned to the low-, moderate-, and high-risk groups based on their probability scores. The Kaplan-Meier survival curves for the different nomogram-based groups were significantly different (p < 0.001). CONCLUSIONS: We developed a nomogram using the LASSO-logistic regression model to forecast the 30-day mortality rate in patients who had undergone ERCP with endobiliary metal stent placement due to MBO. This nomogram can assist in identifying individuals at high-risk of 30-day mortality following ERCP.


Assuntos
Colangiopancreatografia Retrógrada Endoscópica , Colestase , Humanos , Nomogramas , Estudos Retrospectivos , Bilirrubina , Aprendizado de Máquina , Colestase/etiologia , Colestase/cirurgia
5.
J Youth Adolesc ; 52(11): 2300-2313, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37460878

RESUMO

As a severe public health concern directly endangering life safety, adolescent suicide has been extensively investigated in variable-centered studies. However, gaps remain in the knowledge of heterogeneous suicide risk patterns and their developmental nature. Additionally, little is known about protective factors associated with suicide risk patterns and changes. This study applied person-centered approaches to explore suicide risk profiles and transitions over time in early Chinese adolescents, along with their protective factors. A total of 1518 junior high school students (49.6% girls, Mage = 13.57, SD = 0.75) participated in two surveys within a 12-month interval. Latent Profile Analysis and Latent Transition Analysis were used to model the profiles and transitions of suicide risk. Three risk profiles were identified at both time points: low risk profile (73.9, 78.3%), medium risk-high threat profile (16.2, 10.2%), and high risk profile (9.9, 10.2%). Low risk profile was stable, while medium risk-high threat and high risk profiles showed great transitions over 12 months. Sense of control, meaning in life, and regulatory emotional self-efficacy served as protective factors against suicide risk profiles and transitions. Findings underscore the importance of comprehensively illustrating suicide risk states from multiple aspects, as well as understanding the fluid nature of transitions between different risk states. Prevention and intervention strategies aimed at enhancing resilience, such as increasing sense of control, perceived meaningfulness, and belief in emotional regulation, may contribute to reducing the risk of suicide among adolescents.


Assuntos
População do Leste Asiático , Fatores de Proteção , Suicídio , Adolescente , Feminino , Humanos , Masculino , Fatores de Risco , Suicídio/psicologia , Resiliência Psicológica
6.
Child Abuse Negl ; 135: 105947, 2023 01.
Artigo em Inglês | MEDLINE | ID: mdl-36399815

RESUMO

BACKGROUND: Psychological maltreatment has been regarded as a risk factor for adolescent internet harassment. However, previous studies failed to take family, peer, and individual factors into account comprehensively when comes to adolescent internet harassment perpetration. OBJECTIVE: Based on the Social-Ecological Diathesis-Stress Model, the present study established a moderated mediation model to investigate the mediating role of deviant peer affiliation in the association between psychological maltreatment and adolescent internet harassment perpetration, as well as the moderating role of self-compassion. PARTICIPANTS AND SETTING: A total of 1,592 Chinese adolescents (51.07 % girls, Mage = 13.23 years) participated in the current study. METHOD: The participants completed questionnaires regarding demographics, psychological maltreatment, internet harassment perpetration, deviant peer affiliation, and self-compassion. RESULTS: Psychological maltreatment was positively related to adolescent internet harassment perpetration. Mediation analyses revealed that deviant peer affiliation partially mediated this relationship (indirect effect = 0.14, 95 % CI = [0.09, 0.20]). Moderated mediation analyses further indicated that self-compassion not only moderated the link between psychological maltreatment and adolescent internet harassment perpetration, with the effect being significant only for adolescents with low levels of self-compassion, but also moderated the indirect association between psychological maltreatment and internet harassment perpetration via deviant peer affiliation, with the association being much more potent for adolescents with low levels of self-compassion. CONCLUSIONS: This study highlights the importance of considering multiple circumstantial and individual factors to understand the development of adolescents' externalizing problems.


Assuntos
Comportamento do Adolescente , Transtornos Mentais , Feminino , Humanos , Adolescente , Masculino , Autocompaixão , Grupo Associado , Fatores de Risco , Comportamento do Adolescente/psicologia
7.
Biomed Res Int ; 2022: 2652916, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36119922

RESUMO

Craniocerebral injury accounts for 9%-21% of the injuries in all parts of the body, and the incidence rate ranks first in all types of trauma or only lower than limb fractures. This study mainly discusses the nursing methods of patients with severe traumatic brain injury and fractures in ambulances. This study is based on risk factors with moderate-to-higher association strength from retrospective studies. According to the regression coefficients of the logistic regression model, the risk factors were assigned, and the early warning score table of craniocerebral injury complicated with hyponatremia was established. The energy efficiency of the early warning score table was evaluated by case diagnostic test and ROC analysis. At the same time, risk grading is carried out, and the chi-square test is used to test the reliability of the grading standard, so as to identify the risk of hyponatremia in patients with craniocerebral injury early and screen out high-risk patients as the key observation objects of nurses. Based on the early warning score table of craniocerebral injury complicated with hyponatremia, different systematic nursing intervention measures were taken for low-risk patients and high-risk patients, and their application effects were evaluated. The clinical application effect of the systematic nursing intervention program was evaluated by the historical control research method, which provided a reference for the nursing in the ambulance to prevent other complications of patients with craniocerebral injury. The positive rate of prehospital operation can reach 64.44%, and the specific rate can reach 84.44%. 60% of the sample sought better metastatic care in terms of the purpose of using an ambulance. The systematic nursing intervention program has a certain effect on reducing the incidence of hyponatremia in patients with craniocerebral injury and shortening the hospitalization time of patients with craniocerebral injury. The early warning score of craniocerebral injury complicated with hyponatremia developed in this study is concise and practical and can provide a basis for clinical assessment of the risk of hyponatremia in patients with craniocerebral injury.


Assuntos
Lesões Encefálicas Traumáticas , Traumatismos Craniocerebrais , Fraturas Ósseas , Hiponatremia , Ambulâncias , Lesões Encefálicas Traumáticas/complicações , Traumatismos Craniocerebrais/cirurgia , Humanos , Reprodutibilidade dos Testes , Estudos Retrospectivos
8.
Artigo em Inglês | MEDLINE | ID: mdl-36011980

RESUMO

This study aimed to determine the association between coparenting behavior and children's externalizing and internalizing problems and possible factors that may moderate their associations. A meta-analysis of 93 studies involving 41,207 participants found that coparenting behavior was slightly and significantly related to externalizing problems, r = -0.17, 95% CI [-0.194, -0.15], and internalizing problems, r = -0.16, 95% CI [-0.18, -0.14]. In addition, coparenting integrity, cooperation, conflict, competitiveness, and triangulation were significantly related to externalizing and internalizing problems. Moderation analyses revealed the following findings: (a) data reporter moderated the association between coparenting and internalizing problems, with children-report coparenting showing a significantly stronger relation with internalizing symptom than father-report coparenting; (b) developmental stage was found to moderate the association between coparenting behavior and externalizing problems, with stronger association found in childhood than in toddlerhood; (c) female percentage, individualism-collectivism culture, research methods, and publication year were not found to moderate the association between coparenting behavior and externalizing or internalizing problems. These findings help summarize the previous studies and provide an empirical basis for the relation between coparenting and child externalizing/internalizing problems, and benefits targeted interventions towards coparenting behaviors.


Assuntos
Transtornos do Comportamento Infantil , Comportamento Problema , Adolescente , Criança , Comportamento Infantil , Família , Feminino , Humanos , Ajustamento Social
9.
BMC Pediatr ; 22(1): 331, 2022 06 08.
Artigo em Inglês | MEDLINE | ID: mdl-35672682

RESUMO

OBJECTIVES: This study aimed to investigate the prevalence of congenital heart disease (CHD) among school children in Qinghai province, a high-altitude region in China. METHODS: A cross-sectional study was conducted among school-aged children in 2019. All subjects completed a survey with a structure questionnaire and underwent CHD screening. CHD was screened by standard physical examination and further confirmed by echocardiography. Multivariate logistic regression were used to estimate the association of CHD prevalence with gender, nationality, and altitude. RESULTS: A total of 43,562 children aged 3-19 years participated in the study. The mean (SD) age was 11.2 (3.3) years. 49.7% were boys, and 80.0% were of Tibetan. CHD was identified in 293 children, with an overall prevalence of 6.73 ‰. Among them, 239 were unrecognized CHD, yielding a prevalence of 5.49 ‰. Atrial septal defect accounted for 51.9% of the CHD, followed by patent ductus arteriosus (31.1%), ventricular septal defect (9.9%). The CHD prevalence was significantly higher in female (8 ‰), Han race (18 ‰), children lived in Qumalai county (13 ‰), and children lived in a higher altitude (13 ‰). Female had greater prevalence of total CHD, atrial septal defect, and patent ductus arteriosus, but insignificant difference was observed in ventricular septal defect prvalence than male. In multivariable logistic regression analyses, female (OR, 1.48; 95% CI, 1.17-1.87, P = 0.001), Han population (OR, 3.28; 95% CI, 1.67-6.42, P = 0.001), and higher altitudes (OR, 2.28; 95% CI, 1.74-3.00, P < 0.001) were shown to be independently association with CHD prevalence. CONCLUSIONS: The prevalence of CHD in Qinghai province was 6.73 ‰. Altitude elevation, female, and Han population were independently association with CHD prevalence.


Assuntos
Permeabilidade do Canal Arterial , Cardiopatias Congênitas , Comunicação Interatrial , Comunicação Interventricular , Criança , Estudos Transversais , Feminino , Cardiopatias Congênitas/epidemiologia , Humanos , Masculino , Prevalência
10.
J Interpers Violence ; 37(1-2): NP830-NP850, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-32401127

RESUMO

Adolescent depression is a significant concern around the world. There is a pressing need to explore risk factors for this disorder to develop better interventions. Based on an integration of attachment theory, Bronfenbrenner's ecological systems theory, and relational theory, the current study aimed to examine (a) whether childhood emotional abuse (CEA) would be significantly and positively related to adolescents' depression, (b) whether deviant peer affiliation would mediate the relation between CEA and depression, and (c) whether gender would moderate the direct and indirect relations between CEA and adolescent's depression via deviant peer affiliation. Participants were 961 Chinese adolescents (Mage = 15.21 years, SD = 1.57). They completed questionnaires regarding demographics, CEA, other types of childhood maltreatment (i.e., physical abuse, sexual abuse, physical neglect, and emotional neglect), deviant peer affiliation, and depression. Results showed that CEA was positively related to adolescent depression even after controlling for other types of childhood maltreatment, and this relation was mediated by deviant peer affiliation. Furthermore, moderated mediation analyses indicated that gender moderated the relation between CEA and deviant peer affiliation, with the relation being stronger for girls than for boys. However, gender did not moderate the relation between deviant peer affiliation and depression, as well as the direct relation between CEA and depression. Results highlight that interventions aimed at reducing CEA may protect adolescents, especially girls from the risks of deviant peer affiliation and depression.


Assuntos
Comportamento do Adolescente , Maus-Tratos Infantis , Adolescente , Criança , Depressão/epidemiologia , Abuso Emocional , Feminino , Humanos , Masculino , Grupo Associado , Inquéritos e Questionários
11.
J Interpers Violence ; 37(1-2): NP1105-NP1124, 2022 01.
Artigo em Inglês | MEDLINE | ID: mdl-32418471

RESUMO

Recent research has ascertained some risk factors for cyberbullying. However, few studies have investigated the potential influence of difficulties in emotion regulation (DER) on cyberbullying, and there is little knowledge about the mediating mechanisms underlying this association. This study investigated whether DER would be significantly related to adolescent cyberbullying and whether loneliness and depression would sequentially mediate the link between DER and adolescent cyberbullying. A sample of 719 Chinese middle school students completed measures regarding demographics, DER, loneliness, depression, and cyberbullying. After controlling for the demographic covariates, the results showed that (a) DER was positively associated with adolescent cyberbullying; (b) loneliness and depression sequentially mediated the relation between DER and adolescent cyberbullying. This study emphasizes the underlying mediating mechanisms between DER and adolescent cyberbullying, which is of great significance for the prevention and intervention of adolescent cyberbullying in the digital age.


Assuntos
Vítimas de Crime , Cyberbullying , Regulação Emocional , Adolescente , China/epidemiologia , Depressão/epidemiologia , Humanos , Solidão
13.
Artigo em Inglês | MEDLINE | ID: mdl-34769803

RESUMO

Previous studies have primarily focused on the separate mediating role of interpersonal context or personal characteristics in the relationship between childhood psychological maltreatment and depression, neglecting the combined effects, which have limited ecological validity. Therefore, this study investigated the multiple mediating roles of perceived ostracism and core self-evaluation in the relationship between childhood psychological maltreatment and depression. A total of 1592 Chinese adolescents (51.1% boys), ranging in age from 11 to 15 years (M = 13.23, SD = 0.96), completed a self-report questionnaire regarding demographics, psychological maltreatment, perceived ostracism, core self-evaluation and depression. A multiple mediation model was tested using Model 6 of the PROCESS macro. After controlling for the variables of gender and age, the results indicated that perceived ostracism and core self-evaluation parallelly and sequentially mediated the link between psychological maltreatment and depression. The multiple mediation model could account for 55% of the total effect. In conclusion, the current study helps us better understand the mechanisms of depression caused by psychological maltreatment, and contributes to preventing and intervening in depression among Chinese adolescents.


Assuntos
Maus-Tratos Infantis , Autoavaliação Diagnóstica , Adolescente , Criança , China/epidemiologia , Depressão/epidemiologia , Feminino , Humanos , Masculino , Autoavaliação (Psicologia) , Isolamento Social
14.
Med Sci Monit ; 27: e930545, 2021 Aug 16.
Artigo em Inglês | MEDLINE | ID: mdl-34393219

RESUMO

BACKGROUND The incidence, pathogenesis, and prognostic effect of microvascular invasion on pancreatic ductal adenocarcinoma (PDAC) remain controversial. This study aimed to summarize the incidence, pathogenesis, role in clinical management, recurrence, and prognostic significance of microvascular invasion in PDAC. MATERIAL AND METHODS A literature review and meta-analysis were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Systematic literature searches were conducted using PubMed and Google Scholar up to February 2021. RESULTS Seventeen studies were included in the meta-analysis. The incidence of microvascular invasion was 49.0% (95% confidence interval [CI], 43.8-54.5%) among PDAC patients who underwent surgery. The weighted multivariate Cox proportional hazards model hazard ratio for disease-free survival of 8 studies was 1.78 (95% CI 1.53-2.08, P<0.001), and there was no statistically significant difference between the subgroups (P=0.477). The hazard ratio for overall survival of 14 studies was 1.49 (95% CI 1.27-1.74, P<0.001), and there was no statistically significant difference between the subgroups (P=0.676). CONCLUSIONS Microvascular invasion occurred in nearly half of PDAC patients after surgery and was closely related to disease-free and overall survival. Understanding the role of microvascular invasion in PDAC will help provide more personalized and effective preoperative or postoperative strategies to achieve better survival outcomes.


Assuntos
Carcinoma Ductal Pancreático/irrigação sanguínea , Carcinoma Ductal Pancreático/patologia , Invasividade Neoplásica/patologia , Adenocarcinoma/patologia , Carcinoma Ductal Pancreático/metabolismo , Intervalo Livre de Doença , Humanos , Incidência , Microvasos/fisiologia , Neoplasias Pancreáticas/patologia , Prognóstico , Modelos de Riscos Proporcionais , Neoplasias Pancreáticas
15.
J Interpers Violence ; 36(17-18): NP9601-NP9622, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-31286820

RESUMO

Based on an integration of the positive youth development model and the social cognitive theory, friends' moral identity was examined as a moderator of the direct and indirect relations between school climate and adolescent's cyberbullying perpetration via moral disengagement. Participants were 404 Chinese adolescents (Mage = 13.53 years, SD = 0.92). They completed the Perceived School Climate Scale and the Moral Identity Scale and nominated up to three friends whom they considered to be their "best friend" in their classroom at Time 1. After 6 months, they completed the Moral Disengagement Scale and the Cyberbullying Scale at Time 2. Results showed that adolescents who experienced positive school climate were less likely to cyberbully others, which was mediated by their moral disengagement. Friends' moral identity moderated the direct and indirect relations between school climate and cyberbullying perpetration. Specifically, the indirect relationship between school climate and cyberbullying perpetration through moral disengagement became nonsignificant for adolescents interacting with high moral identity friends. The direct association between school climate and cyberbullying perpetration was moderated by friends' moral identity.


Assuntos
Bullying , Cyberbullying , Adolescente , Amigos , Humanos , Princípios Morais , Instituições Acadêmicas
16.
J Affect Disord ; 279: 75-82, 2021 01 15.
Artigo em Inglês | MEDLINE | ID: mdl-33039777

RESUMO

News media workers are in stressful and competitive professions susceptible to negative emotions. Although the relationship between negative emotions and job burnout has been evidenced in some professional fields, it has not yet been examined in the population of news media workers. Far few studies have revealed the mediating and moderating mechanism between negative emotions and job burnout. Based on Resource Allocation Theory and Theory of Compassion Fatigue, this study examined (a) the mediating role of rumination in the relationship between negative emotions and job burnout, (b) the moderating role of empathy in the direct and indirect effect of negative emotions on job burnout, and (c) the moderating role of gender in the direct effect of negative emotions on rumination. Two hundred and eleven Chinese news media workers filled out questionnaires regarding negative emotions, job burnout, rumination, and empathy. The results indicated that negative emotions were positively correlated with job burnout. Mediation analysis revealed that rumination partially mediated the association between negative emotions and job burnout. Moderated mediation analysis further indicated that empathy moderated the effect of negative emotions on rumination, with a high level of empathy strengthening the association between negative emotions and rumination; gender moderated the effect of negative emotions on rumination, with the association between negative emotions and rumination was stronger among males than females. These findings encourage to design psychological interventions to reduce rumination and express proper empathy in the face of stress or negative affective status to avoid job burnout among news media workers.


Assuntos
Esgotamento Profissional , Fadiga de Compaixão , Emoções , Empatia , Feminino , Humanos , Satisfação no Emprego , Masculino , Inquéritos e Questionários
17.
Cancer Manag Res ; 12: 5997-6006, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32765099

RESUMO

PURPOSE: Pancreatic cancer (PC) has poor prognosis despite systemic treatment. Dehydrogenase/reductase member 9 (DHRS9) has been reported to be involved in many events of tumorigenesis, but its prognostic impact in PC remains undetermined. Thus, this study aimed to explore the association between DHRS9 expression and the prognosis of PC and investigate the possible mechanism by which DHRS9 is involved in PC progression. PATIENTS AND METHODS: The study used data: from Gene Expression Omnibus (GEO) and our institution to compare the DHRS9 expression between PC and adjacent normal tissues; from The Cancer Genome Atlas (TCGA) and our institution to assess the clinicopathological characteristics and prognosis of PC patients in high and low DHRS9 expression groups; and from TCGA to predict the potential mechanism of DHRS9 in PC. Western blot assay was used to identify DHRS9 expression in specimens collected from five patients who underwent surgery in our institute. Furthermore, immunohistochemistry (IHC) was then used to identify DHRS9 expression in the specimens of 109 patients who underwent surgery at our institute. Kaplan-Meier and Cox regression analyses were used to assess the prognostic significance of DHRS9 expression among PC patients. RESULTS: All the IHC, Western blot, and GEO datasets indicated that compared to normal tissues, DHRS9 was significantly overexpressed in PC tissues. IHC results demonstrated that the strong intensity of DHRS9 expression was significantly correlated with vascular infiltration (P < 0.05). Further, high DHRS9 expression was identified as a prognostic risk factor for overall survival. Functional analysis of DHRS9 co-expressed genes indicated that DHRS9 was involved in mitogen-activated protein kinases/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway. CONCLUSION: DHRS9 is upregulated in PC tissue, and high DHRS9 expression is correlated with poor prognosis in PC. DHRS9 may affect the oncological process of PC through MAPK/ERK pathway.

18.
Int J Clin Health Psychol ; 20(2): 118-125, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32550851

RESUMO

BACKGROUND/OBJECTIVE: Depression, anxiety and stress are known as negative emotions. Previous studies have shown that negative emotions were associated with quality of life. There are a lot of researches on quality of life. However, previous studies mainly focused on health-related quality of life among patients. This study aims to examine the relationship between negative emotions and quality of life as well as the underlying psychological mechanism among community-based samples. METHOD: We surveyed 6,401 adolescents (age: 9-15 years old). Participants were assessed using the Depression Anxiety Stress Scale, Resilience Scale for Chinese Adolescent, Perceived Social Support Scale and the Pediatric Quality of Life Inventory 4.0 Generic Scale for Negative Emotions, Resilience, Social Support and Quality of Life. RESULTS: Results revealed that negative emotions were negatively associated with quality of life, and resilience mediated the relationship between negative emotions and quality of life. Social support moderated all the paths among negative emotions, resilience and quality of life. CONCLUSIONS: Adolescents' quality of life was indirectly affected by negative emotions via resilience, and less affected by negative emotions and more affected by resilience with the improvement of social support. The theoretical and practical implications of these results are discussed.


ANTECECENTES/OBJETIVO: Estrés, ansiedad y depresión son emociones negativas. Estudios previos mostraron que las emociones negativas se asocian con la calidad de vida. Existen numerosas investigaciones centradas en la calidad de vida, sin embargo, los estudios se centran en la calidad de vida de pacientes en relación con su salud. En este estudio se examina la relación entre emociones negativas y calidad de vida, y los mecanismos psicológicos subyacentes. MÉTODO: Encuestamos a 6.401 adolescentes (9-15 años). Los participantes fueron evaluados con la Depression Anxiety Stress Scale, la Resilience Scale for Chinese Adolescent, la Perceived Social Support Scale y el Pediatric Quality of Life Inventory 4.0 Generic Scale for Negative Emotions, Resilience, Social Support and Quality of Life. RESULTADOS: Las emociones negativas fueron negativamente asociadas con la calidad de vida, y la resiliencia medió la relación entre emociones negativas y calidad de vida. El apoyo social moderó todas las vías entre emociones negativas, resiliencia y calidad de vida. CONCLUSIONES: La calidad de vida de los adolescentes fue indirectamente afectada por las emociones negativas mediante la resiliencia, menos afectada por emociones negativas y más afectada por la resiliencia con la mejora en el apoyo social. Se discuten las implicaciones teóricas y prácticas de estos resultados.

19.
J Youth Adolesc ; 49(7): 1565, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32504341

RESUMO

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

20.
Child Abuse Negl ; 106: 104507, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32361515

RESUMO

BACKGROUND: Childhood maltreatment plays an important role in adolescents' bullying perpetration. However, the mediating and moderating mechanisms underlying this association remain largely unknown. OBJECTIVES: The current study examined the relationship between childhood maltreatment and adolescents' bullying perpetration and extended previous literature by examining the mediating effect of moral disengagement and the moderating effect of trait anger in this relationship. PARTICIPANTS AND SETTING: Four hundred and thirty-five Chinese adolescents (228 girls, mean age = 13.55 years) participated in the current study. METHODS: Our theoretical model was examined using a short-term longitudinal design. During the fall of 2016, adolescents completed the Childhood Trauma Questionnaire-Short Form. After six months, they completed the moral disengagement Scale, the Bullying Scale, and the Trait Anger Scale in the spring of 2017. RESULTS: The results indicated that childhood maltreatment positively predicted adolescents' bullying perpetration at six months later, and moral disengagement mediated this relationship. Trait anger moderated the relationship between moral disengagement and bullying perpetration, but not the relationship between childhood maltreatment and bullying perpetration. Specifically, high trait anger adolescents who had higher levels of moral disengagement were more likely to bully their peers than low trait anger adolescents. CONCLUSIONS: These findings indicate that childhood maltreatment plays an important role in adolescents' bullying perpetration, and this relationship is mediated by moral disengagement. Moreover, trait anger moderates the relationship between moral disengagement and bullying perpetration. Educators who examine adolescents' bullying perpetration should pay closer attention to their moral disengagement and trait anger, as well as their childhood maltreatment experiences, in order to provide appropriate interventions.


Assuntos
Comportamento do Adolescente/psicologia , Ira , Bullying/psicologia , Maus-Tratos Infantis/psicologia , Princípios Morais , Adolescente , Povo Asiático/psicologia , Feminino , Humanos , Masculino , Análise de Mediação , Inquéritos e Questionários
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