A longitudinal study on the effect of extreme temperature on non-accidental deaths in Hulunbuir City based on DLNM model.

OBJECTIVE: To explore the frequency and effect of extreme temperature on the non-accidental death rate in Hulunbuir, a Chinese ice city. METHODS: From 2014 to 2018, mortality data of residents residing in Hulunbuir City were collected. The lag and cumulative effects of extreme temperature conditions on non-accidental death and respiratory and circulatory diseases were analyzed by distributed lag non-linear models (DLNM). RESULTS: The risk of death was the highest during high-temperature conditions, the RR value was 1.111 (95% CI 1.031 ~ 1.198). The effect was severe and acute. The risk of death during extreme low-temperature conditions peaked on the fifth day, (RR 1.057; 95% CI 1.012 ~ 1.112), then decreased and was maintained for 12 days. The cumulative RR value was 1.289 (95% CI 1.045 ~ 1.589). Heat significantly influenced the incidence of non-accidental death in both men (RR 1.187; 95% CI 1.059-1.331) and women (RR 1.252; 95% CI 1.085-1.445). CONCLUSIONS: Regardless of the temperature effect, the risk of death in the elderly group (≥ 65 years) was significantly higher than that of the young group (0-64 years). High-temperature and low-temperature conditions can contribute to the increased number of deaths in Hulunbei. While high-temperature has an acute effect, low-temperature has a lagging effect. Elderly and women, as well as people with circulatory diseases, are more sensitive to extreme temperatures.

[Randomized controlled clinical trials for treatment of external sty with ear-apex blood-letting].

OBJECTIVE: To observe the clinical therapeutic effect of ear-apex blood-letting for external sty. METHODS: A total 102 sty patients were randomized into ear-apex blood-letting group (n = 51) and routine treatment (medication) group (n = 51) according to computer-aided randomization procedure. Ear-apex-bloodletting (5-6 blood drops/time) was performed once daily for 3 times for the patients of blood-letting group. Patients of the medication group were treated by local application of hydrochloric levofloxacin and erycin ointment to the affected eyelid lining. Additionally, local warm compress of the affected eyelid was given to patients of both groups. The therapeutic effect was assessed by measuring the size of the sty swell and visual analogue scale (VAS) was determined for evaluating pain severity changes. The outcomes were analyzed by researchers who did not know the grouping. RESULTS: Comparison between patients of the two groups showed that the difference vahees of the styrize and VAS score between pre- and post-treatment in the ear-apex bloodletting group were significantly bigger than those of the medication group on day 3, 5 and 7 after treatment (P<0.05). The cure rates of the blood-letting group and medication group were 64.7% and 41.2%, 90.2% and 62.7%, 94. 1% and 80.4%, respectively on day 3, 5 and 7 after the treatment. The therapeutic effects of blood-letting were significantly superior to those of the medication group in relieving external sty (P<0.05). CONCLUSION: Ear-apex blood-letting therapy for external sty is effective in relieving pain, reducing the size and shortening the duration of disease.