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1.
Ying Yong Sheng Tai Xue Bao ; 33(3): 844-854, 2022 Mar.
Artigo em Chinês | MEDLINE | ID: mdl-35524540

RESUMO

Plants, grown in the immobile soils, have evolved various strategies in response to environmental stresses, including the "stress memory" and "defense priming" mechanisms. The environmental stresses cannot immediately change the DNA base sequence in plants in the short-term. Therefore, epigenetic inheritance is a key mechanism for stress memory and defense priming. In particular, histone modification is considered to be the most important mechanism, which offers the possibility of stress memory. We summarized research advances in plant histone modifications involved in stress memory and defense priming under biotic and abiotic stresses, and proposed pro-blems in the field and the focus and directions in the future research. In-depth understanding of the relationship between histone modification and environmental stresses would facilitate the quick adaptation of plants to harsh environments, and provide theoretical and technical guidance for plant phenotype shaping, organ regeneration, and crop genetic improvement.


Assuntos
Regulação da Expressão Gênica de Plantas , Código das Histonas , Epigênese Genética , Histonas/genética , Plantas/genética , Estresse Fisiológico
2.
Chin J Nat Med ; 18(4): 296-307, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32402407

RESUMO

Hydrogen sulfide (H2S) is commonly referred to as the third gasotransmitter with firmly established physiological roles. Prodrug approaches have been broadly applied to deliver H2S for various applications and mechanistic studies. Since S-persulfidation and glutathionylation are known to be important in cellular signaling by sulfur species, there have been interests in developing donors of persulfide and glutathione persulfide as well. In this review, we discuss the recent development in area of prodrugs for various sulfur species.


Assuntos
Sulfeto de Hidrogênio/química , Sulfeto de Hidrogênio/farmacologia , Pró-Fármacos/química , Pró-Fármacos/farmacologia , Sulfetos/química , Sulfetos/farmacologia , Desenvolvimento de Medicamentos , Humanos , Estrutura Molecular
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