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Sci Rep ; 9(1): 15979, 2019 11 04.
Artigo em Inglês | MEDLINE | ID: mdl-31685849

RESUMO

Chlamydia trachomatis (CT) infection is an important factor for tubal pregnancy. However, whether Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) infections are also involved in tubal pregnancy remains unknown. This study is aimed to detect CT, UU, and MH in cervical secretions from patients with tubal pregnancy and control women in early pregnancy, to explore their prevalence rates and drug susceptibilities. Analysis was performed on patients with tubal pregnancy and those requiring termination of early pregnancy at <12 weeks from July 2013 to March 2014. Cervical secretions were tested for UU/MH with a UU/MH isolation and culture kit and for CT antigen by an immunochromatographic assay. Mycoplasma samples were tested for resistance to 12 antibiotics. There were no cases of CT infection detected. Mycoplasma infection rates (single or mixed) were similar in the tubal pregnancy and control groups, but the total rate of infection was higher for tubal pregnancy. All MH samples were sensitive to tetracyclines as well as josamycin and azithromycin. Josamycin and clarithromycin were effective against all UU cultures. Over 50% of the samples tested were resistant to ciprofloxacin.


Assuntos
Infecções por Chlamydia/complicações , Infecções por Chlamydia/microbiologia , Chlamydia trachomatis , Infecções por Mycoplasma/complicações , Infecções por Mycoplasma/microbiologia , Gravidez Tubária/etiologia , Adulto , Antibacterianos/farmacologia , Antibacterianos/uso terapêutico , Infecções por Chlamydia/diagnóstico , Infecções por Chlamydia/epidemiologia , Chlamydia trachomatis/efeitos dos fármacos , Suscetibilidade a Doenças , Farmacorresistência Bacteriana , Feminino , Humanos , Testes de Sensibilidade Microbiana , Infecções por Mycoplasma/diagnóstico , Infecções por Mycoplasma/epidemiologia , Gravidez , Gravidez Tubária/diagnóstico , Gravidez Tubária/epidemiologia , Medição de Risco , Fatores de Risco , Adulto Jovem
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