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1.
PLoS One ; 19(5): e0303149, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38722869

RESUMO

Carbon emissions have become a global challenge, and China, as the world's largest developing country, has a serious emissions problem. Developing green buildings is an important way of reducing carbon emissions. China's low-carbon city pilot policy may be an effective way of promoting green building development and reducing these emissions. This study uses the low carbon city pilot policy as a quasi-natural experiment and employs the staggered difference-in-differences method to investigate its impact on green building development. The results show that the low-carbon city pilot policy promotes green building development, and this policy promotes it by enhancing regional green innovation capacity, improving green total factor productivity at the firm and regional levels, and reducing the financing constraints of firms in the construction and real estate sectors. In addition, the promotion effect of the policy on green building development is stronger in western and non-resource-based regions and large-scale cities in China. This study contributes to the literature related to environmental policy, green building, and carbon emissions and supports the promotion of green building development and the reduction of carbon emissions.


Assuntos
Carbono , Política Ambiental , Desenvolvimento Sustentável , China , Cidades , Humanos , Indústria da Construção , Conservação dos Recursos Naturais/métodos
2.
Small ; : e2402841, 2024 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-38693072

RESUMO

Developing lightweight composite with reversible switching between microwave (MW) absorption and electromagnetic interference (EMI) shielding is promising yet remains highly challenging due to the completely inconsistent attenuation mechanism for electromagnetic (EM) radiation. Here, a lightweight vanadium dioxide/expanded polymer microsphere composites foam (VO2/EPM) is designed and fabricated with porous structures and 3D VO2 interconnection, which possesses reversible switching function between MW absorption and EMI shielding under thermal stimulation. The VO2/EPM exhibits MW absorption with a broad effective absorption bandwidth of 3.25 GHz at room temperature (25 °C), while provides EMI shielding of 23.1 dB at moderately high temperature (100 °C). This reversible switching performance relies on the porous structure and tunability of electrical conductivity, complex permittivity, and impedance matching, which are substantially induced by the convertible crystal structure and electronic structure of VO2. Finite element simulation is employed to qualitatively investigate the change in interaction between EM waves and VO2/EPM before and after the phase transition. Moreover, the application of VO2/EPM is demonstrated with a reversible switching function in controlling wireless transmission on/off, showcasing its excellent cycling stability. This kind of smart material with a reversible switching function shows great potential in next-generation electronic devices.

3.
ISA Trans ; 2024 Apr 17.
Artigo em Inglês | MEDLINE | ID: mdl-38653682

RESUMO

Accurate degradation trend prediction (DTP) is crucial for optimizing equipment operation and maintenance, thereby boosting production efficiency. This study introduces a novel Data Repair and Dual-data-stream LSTM (DR-DLSTM) network to tackle the challenge of missing data in equipment DTP. The proposed DR-DLSTM framework employs convex optimization to consider both the trend and periodic variations in the data, incorporating polynomial and trigonometric functions into the implicit feature matrix to construct latent vectors for missing data rectification. The network features a Dual-LSTM block with dual data streams to enhance feature extraction, with two gating update units correlating time series components and redistributing feature weights. The Dual-LSTM enables separate and accurate prediction of trend and periodic components, thereby enhancing the feature extraction capability of the prediction model. Additionally, the integration of physical rule information through Fourier and wavelet transform frequency correction modules allows for dynamic adjustments in prediction outcomes, from global trends to localized details. The DR-DLSTM's effectiveness is demonstrated through comprehensive comparisons with state-of-the-art models across multiple datasets, highlighting its superior performance. The results demonstrate the superiority of the proposed model. These algorithms were implemented in Python using Torch on a 2.9 GHz Intel I7 CPU and TITAN Xp GPU.

4.
Toxicon ; 243: 107723, 2024 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-38663519

RESUMO

Tumor-associated macrophages within the tumor microenvironment play an immunosuppressive role by promoting tumor growth and immune evasion. Macrophages are highly plastic and can be stimulated to adopt an anti-tumor M1 phenotype. In this study, we used microcystin-LR (MC-LR), a cyclic heptapeptide produced by cyanobacteria, to induce in vitro macrophage innate immunity and transition into the anti-tumor M1 phenotype. MC-LR was also tested in vivo in a mouse model of colorectal cancer. An intraperitoneal injection of MC-LR increased the proportion of CD86⁺ M1 macrophages and triggered the maturation of CD11c⁺ dendritic cells within tumor tissues. MC-LR combined with the chemotherapeutic drug oxaliplatin significantly inhibited tumor growth in vivo. Flow cytometry analysis revealed increased infiltration of activated cytotoxic (CD8⁺, PD-1⁺) T-cells and anti-tumor cytokines (IFNγ and Granzyme B) in the tumor tissues of the combination therapy group, suggesting that this may be the primary mechanism behind the anti-tumor effect of the combination treatment. These findings indicate that MC-LR regulates the immune stimulation of macrophage polarization and dendritic cell maturation, effectively reversing tumor immunosuppression, activating an anti-tumor immune response, and enhancing tumor therapy.

5.
Toxicol Ind Health ; 40(6): 312-322, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38590048

RESUMO

Previous epidemiologic research has shown that phthalate exposure in pregnant women is related to adverse birth outcomes in a sex-specific manner. However, the biological mechanism of phthalate exposure that causes these birth outcomes remains poorly defined. In this research, we investigated the association between phthalate exposure and placental oxidative stress in a large population-based cohort study, aiming to initially explore the relationship between phthalate exposure and gene expression in placental oxidative stress in a sex-specific manner. Quantitative PCR was performed to measure the expression of placental inflammatory mRNAs (HO-1, HIF1α, and GRP78) in 2469 placentae. The multiple linear regression models were used to investigate the associations between mRNA and urinary phthalate monoesters. Phthalate metabolites monomethyl phthalate (MMP) and mono-n-butyl phthalate (MBP) were positively correlated with higher HIF1α expression in placentae of male fetuses (p < .05). Mono-benzyl phthalate (MBzP) increased the expression of HO-1, HIF1α, and GRP78 in placentae of male fetuses, and mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) up-regulated the expression of HIF1α and GRP78. Additionally, mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) was negatively correlated with HO-1, HIF1α, and GRP78 in placentae of female fetuses. Maternal phthalate exposure was associated with oxidative stress variations in placental tissues. The associations were closer in the placentas of male fetuses than in that of female ones. The placenta oxidative stress is worth further investigation as a potential mediator of maternal exposure-induced disease risk in children.


Assuntos
Biomarcadores , Chaperona BiP do Retículo Endoplasmático , Exposição Materna , Estresse Oxidativo , Ácidos Ftálicos , Placenta , Humanos , Ácidos Ftálicos/toxicidade , Ácidos Ftálicos/urina , Feminino , Estresse Oxidativo/efeitos dos fármacos , Gravidez , Masculino , Placenta/efeitos dos fármacos , Placenta/metabolismo , Biomarcadores/urina , Estudos Prospectivos , Adulto , Exposição Materna/efeitos adversos , Fatores Sexuais , Subunidade alfa do Fator 1 Induzível por Hipóxia/metabolismo , Heme Oxigenase-1/metabolismo , Heme Oxigenase-1/genética , Proteínas de Choque Térmico/metabolismo , Proteínas de Choque Térmico/genética , Estudos de Coortes
6.
Food Chem ; 448: 138575, 2024 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-38604110

RESUMO

Quinoa sprouts are a green vegetable rich in bioactive chemicals, which have multiple health benefits. However, there is limited information on the overall metabolic profiles of quinoa sprouts and the metabolite changes caused by saline-alkali stress. Here, a UHPLC-MS/MS-based widely targeted metabolomics technique was performed to comprehensively evaluate the metabolic profiles of quinoa sprouts and characterize its metabolic response to saline-alkali stress. A total of 930 metabolites were identified of which 232 showed significant response to saline-alkali stress. The contents of lipids and amino acids were significantly increased, while the contents of flavonoids and phenolic acids were significantly reduced under saline-alkali stress. Moreover, the antioxidant activities of quinoa sprouts were significantly affected by saline-alkali stress. The enrichment analysis of the differentially accumulated metabolites revealed that flavonoid, amino acid and carbohydrate biosynthesis/metabolism pathways responded to saline-alkali stress. This study provided an important theoretical basis for evaluating the nutritional value of quinoa sprouts and the changes in metabolites in response to saline-alkali stress.


Assuntos
Álcalis , Chenopodium quinoa , Flavonoides , Valor Nutritivo , Chenopodium quinoa/química , Chenopodium quinoa/metabolismo , Chenopodium quinoa/crescimento & desenvolvimento , Álcalis/química , Álcalis/metabolismo , Flavonoides/metabolismo , Flavonoides/análise , Flavonoides/química , Cromatografia Líquida de Alta Pressão , Antioxidantes/metabolismo , Antioxidantes/química , Metabolômica , Espectrometria de Massas em Tandem , Aminoácidos/metabolismo , Aminoácidos/análise , Estresse Fisiológico
7.
Hepatobiliary Surg Nutr ; 13(2): 198-213, 2024 Apr 03.
Artigo em Inglês | MEDLINE | ID: mdl-38617471

RESUMO

Background: Adequate evaluation of degrees of liver cirrhosis is essential in surgical treatment of hepatocellular carcinoma (HCC) patients. The impact of the degrees of cirrhosis on prediction of post-hepatectomy liver failure (PHLF) remains poorly defined. This study aimed to construct and validate a combined pre- and intra-operative nomogram based on the degrees of cirrhosis in predicting PHLF in HCC patients using prospective multi-center's data. Methods: Consecutive HCC patients who underwent hepatectomy between May 18, 2019 and Dec 19, 2020 were enrolled at five tertiary hospitals. Preoperative cirrhotic severity scoring (CSS) and intra-operative direct liver stiffness measurement (DSM) were performed to correlate with the Laennec histopathological grading system. The performances of the pre-operative nomogram and combined pre- and intra-operative nomogram in predicting PHLF were compared with conventional predictive models of PHLF. Results: For 327 patients in this study, histopathological studies showed the rates of HCC patients with no, mild, moderate, and severe cirrhosis were 41.9%, 29.1%, 22.9%, and 6.1%, respectively. Either CSS or DSM was closely correlated with histopathological stages of cirrhosis. Thirty-three (10.1%) patients developed PHLF. The 30- and 90-day mortality rates were 0.9%. Multivariate regression analysis showed four pre-operative variables [HBV-DNA level, ICG-R15, prothrombin time (PT), and CSS], and one intra-operative variable (DSM) to be independent risk factors of PHLF. The pre-operative nomogram was constructed based on these four pre-operative variables together with total bilirubin. The combined pre- and intra-operative nomogram was constructed by adding the intra-operative DSM. The pre-operative nomogram was better than the conventional models in predicting PHLF. The prediction was further improved with the combined pre- and intra-operative nomogram. Conclusions: The combined pre- and intra-operative nomogram further improved prediction of PHLF when compared with the pre-operative nomogram. Trial Registration: Clinicaltrials.gov Identifier: NCT04076631.

8.
Mol Omics ; 2024 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-38623715

RESUMO

Kidney stone disease (KSD, also named renal calculi, nephrolithiasis, or urolithiasis) is a common urological disease entailing the formation of minerals and salts that form inside the urinary tract, frequently caused by diabetes, high blood pressure, hypertension, and monogenetic components in most patients. 10% of adults worldwide are affected by KSD, which continues to be highly prevalent and with increasing incidence. For the identification of novel therapeutic targets in KSD, we adopted high-throughput sequencing and mass spectrometry (MS) techniques in this study and carried out an integrative analysis of exosome proteomic data and DNA methylation data from blood samples of normal and KSD individuals. Our research delineated the profiling of exosomal proteins and DNA methylation in both healthy individuals and those afflicted with KSD, finding that the overexpressed proteins and the demethylated genes in KSD samples are associated with immune responses. The consistency of the results in proteomics and epigenetics supports the feasibility of the comprehensive strategy. Our insights into the molecular landscape of KSD pave the way for a deeper understanding of its pathogenic mechanism, providing an opportunity for more precise diagnosis and targeted treatment strategies for KSD.

9.
Front Cardiovasc Med ; 11: 1286620, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38576421

RESUMO

Background: Chemotherapy with anthracyclines can cause cardiotoxicity, possibly leading to stopping treatment in some cancer patients. In cardio-oncology research, preventing and minimizing anthracycline-induced cardiotoxicity (AIC) is a hot issue. For the treatment of AIC, calycosin (CA), an isoflavone component in astragali radix (AR), has become a research focus. However, the elaborate mechanisms of calycosin treating AIC remain to be unrevealed. Aim of the study: To explore the effects of CA on AIC through multiple dimensions concerning network pharmacology, molecular docking, and experimental evaluations. Methods: The study evaluated calycosin's potential targets and mechanisms for treating AIC using network pharmacology and molecular docking. The candidate genes/targets of CA and AIC were screened using the online-available database. Protein-protein interactions (PPI) between the common targets were constructed using the STRING platform, and the results were then visualized using Cytoscape. Molecular docking was used to evaluate the strength of the binding force between CA and the common targets. The possible pharmacological mechanisms of CA were explained by pathway enrichment and GSEA. Subsequently, the candidate targets were identified in vitro experiments. Results: Network pharmacology effectively discovered the CA's multitarget intervention in AIC, including TNF, ABCC1, TOP2A, ABCB1, and XDH. CA binds to the ATP-binding cassette subfamily B member 1(ABCB1) had the highest binding energy (-7.5 kcal/mol) according to the molecular docking analysis and was selected and visualized for subsequent analysis. In vitro experiments showed that ABCB1 exhibited significant time-curve changes under different doses of doxorubicin (DOX) compared with DMSO control experiments. The anti-AIC pharmacological mechanism of CA were revealed by highlighting the biological processes of oxidative stress (OR) and inflammation. Conclusions: We employed a practicable bioinformatics method to connect network and molecular docking to determine the calycosin's therapeutic mechanism against AIC and identified some bioinformatics results in in vitro experiments. The results presented show that CA may represent an encouraging treatment for AIC.

10.
Sci Rep ; 14(1): 9580, 2024 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-38671053

RESUMO

Kagome superconductors AV3Sb5 (A = K, Rb, and Cs) have attracted enormous interest due to the coexistence of charge density wave (CDW) order, unconventional superconductivity (SC) and anomalous Hall effect (AHE). In this paper, we reported an intensive investigation on Cs(V1-xTax)3Sb5 single crystals with systematic Ta doping. Ta was confirmed to be doped into V-site in the Kagome layer from both single crystal X-ray diffraction structural refinement and scanning transmission electron microscopy observation. The highest Ta doping level was found to be about 16%, which is more than twice as much as 7% in Nb-doped CsV3Sb5. With the increase of Ta doping, CDW order was gradually suppressed and finally vanished when the doping level reached to more than 8%. Meanwhile, superconductivity was enhanced with a maximum critical temperature (Tc) of 5.3 K, which is the highest Tc in the bulk crystal of this Kagome system at ambient pressure so far. The µ0Hc2(T) behavior demonstrates that the system is still a two-band superconductor after Ta doping. Based on the electrical transport measurement, a phase diagram was set up to exhibit the evolution of CDW and SC in the Cs(V1-xTax)3Sb5 system. These findings pave a new way to search for new superconductors with higher Tc in the AV3Sb5 family and establish a new platform for tuning and controlling the multiple orders and superconducting states.

11.
iScience ; 27(4): 109516, 2024 Apr 19.
Artigo em Inglês | MEDLINE | ID: mdl-38591004

RESUMO

The recent surge in dam construction has sparked debates regarding their contribution to carbon neutrality and food security, focusing on trade-offs between production benefits and ecological drawbacks. However, how dams affect carbon emissions and land cover changes, including their spatial differentiations, remains unclear. We quantified spatiotemporal variations in carbon emissions and storage of 137 large dams in China from 1992 to 2020, resulting from land cover change in potentially affected areas. We observed a lesser increase in carbon emissions and a more pronounced increase in carbon storage driven by forest conservation and regeneration within dam-affected areas compared to unaffected areas. Additionally, we noticed an increased grain yield in nearby areas potentially due to increased water availability. Our findings highlight the importance of considering land cover change when assessing carbon neutrality or grain yield at regional and national scales. This study provides useful insights into optimizing dam locations to mitigate future carbon emissions effectively.

12.
Artigo em Inglês | MEDLINE | ID: mdl-38609168

RESUMO

CONTEXT: The putative association between proinflammatory and hyperinsulinemic dietary patterns and susceptibility to gestational diabetes mellitus (GDM) remains unclear. OBJECTIVE: We aimed to compare the risk associated with the Mediterranean diet, as well as insulinemic and proinflammatory dietary patterns, in relation to the occurrence of GDM, and evaluate their predictive value. METHODS: We prospectively followed 8, 495 women from the Maternal and Infant Health cohort in Hefei, China (2015-2021). Using a food frequency questionnaire, we calculated the Empirical Dietary Inflammatory Pattern (EDIP), the Empirical Dietary Index for Hyperinsulinemia (EDIH) score, and the Mediterranean diet (MD) score. GDM was diagnosed based on a 2-hour 75-gram oral glucose tolerance test conducted between 24 to 28 weeks of gestation. Logistic regression was used to estimate the risk of GDM, while Receiver Operating Characteristic (ROC) curves were constructed to evaluate the predictive performance of the empirical dietary index for GDM. RESULTS: Participants who followed hyperinsulinemic or proinflammatory dietary patterns to the greatest extent had a higher risk of developing GDM. The OR for the highest quartile compared to the lowest quartile were 1.39 (95% CI: 1.30-1.49) for EDIH and 2.40 (95% CI: 1.88-3.01) for EDIP. The OR for the lowest quartile compared to the highest quartile was 1.33 (95% CI:1.14-1.55)for MD. The ROC curve analysis indicated that the combination of EDIP and EDIH (AUC = 0.81, 95% CI: 0.78-0.82, P = 0.003) can effectively predict the occurrence of GDM. CONCLUSIONS: Utilizing both empirical dietary indexes, EDIP and EDIH, might offer a potentially more effective approach in preventing GDM when compared to solely focusing on adherence to the Mediterranean diet pattern.

13.
Heliyon ; 10(7): e28465, 2024 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-38596109

RESUMO

Background: Grade IV circular hemorrhoids are difficult to treat. We aim to describe the modified whitehead hemorrhoidectomy procedure and to assess the effectiveness and safety of this procedure for grade IV circular hemorrhoid patients. Methods: Patients with grade Ⅳ circular hemorrhoids who underwent modified Whitehead hemorrhoidectomy and partial hemorrhoidectomy for fourth-degree circular mixed hemorrhoids were retrospectively reviewed. Clinical data were extracted from the database at our institution, and long-term postoperative complications were assessed through repeated outpatient examinations and telephonic communication. Results: A total of 205 patients were included in this study. The mean operative time was 59.2 ± 13.8 min. The average hospital stay was 4.6 ± 1.0 days. For postoperative complications, 66 (32.2%) patients had urinary retention, 10 (4.9%) patients had a sense of incomplete rectal emptying, 5 (2.4%) patients had anal incontinence, and 6 (2.9%) patients had wound infection. For long-term postoperative complications, 3 (1.5%) patients experienced mild to moderate anal stricture, 2 (1%) patients experienced mucosal ectropion, they all had smooth recoveries, and none of them needed secondary surgery. None of these patients had a hemorrhoid recurrence. A total of 205 patients who received modified Whitehead hemorrhoidectomy and 161 who received partial hemorrhoidectomy were included. There were no residual hemorrhoids in patients who received modified Whitehead hemorrhoidectomy, and none had hemorrhoid recurrence. Fifty-eight patients who received partial hemorrhoidectomy had hemorrhoidal residues, and 19 patients experienced hemorrhoid recurrence. After modified Whitehead hemorrhoidectomy, 3 patients developed anal stenosis, and 2 had mucosal ectropion. Four patients developed anal stricture after partial hemorrhoidectomy, and none had mucosal ectropion. They all had smooth recoveries, and none of them needed a secondary surgery. For the mean duration of surgery, postoperative bleeding, postoperative pain, wound infection, sense of incomplete rectal emptying, anal incontinence, and urinary retention, no statistically significant differences were found between the two groups. Conclusions: Compared with partial hemorrhoidectomy, modified whitehead hemorrhoidectomy is an effective and safe surgical procedure and does not significantly increase the risk of anal stenosis and mucosal ectropion for grade IV circular hemorrhoid patients. Prospective randomized controlled trials are needed to verify our results.

14.
Medicine (Baltimore) ; 103(17): e37922, 2024 Apr 26.
Artigo em Inglês | MEDLINE | ID: mdl-38669380

RESUMO

RATIONALE: Immunoglobulin G4-related disease (IgG4-RD) can involve various organs throughout the body, primarily manifesting as endocrine dysfunction, visual impairment, jaundice, and limited sexual function. IgG4-related autoimmune pancreatitis is triggered by autoimmune reactions and characterized by structural changes in the pancreas and pancreatic ducts. The disease mainly affects middle-aged and elderly males, typically presenting as progressive painless jaundice and misdiagnosed as cholangiocarcinoma or pancreatic cancer. PATIENT CONCERNS: This study reports a 54-year-old male who consulted with different institutions multiple times due to diabetes, pancreatitis, elevated liver enzymes, and jaundice. DIAGNOSES: Magnetic resonance imaging revealed swollen head of the pancreas and atrophic tail. Liver and pancreatic tissue pathology showed IgG4 plasma cell infiltration, while liver biopsy indicated interface hepatitis, liver fibrosis, and pseudolobule formation, with no evidence of bile duct damage. INTERVENTIONS: Following hormone therapy, the patient's serum IgG4 levels and liver enzyme levels returned to normal. OUTCOMES: The disease relapsed 2 years after maintaining hormone therapy, and the patient underwent additional hormone-induced remission therapy combined with azathioprine. LESSONS: The purpose of this research report is to enhance the awareness and understanding of IgG4-RD, emphasizing the necessity for personalized treatment strategies that take into account its recurrence, associations, and imaging features. This report provides valuable insights and guidance for clinicians in managing and diagnosing patients with IgG4-RD.


Assuntos
Pancreatite Autoimune , Colangite Esclerosante , Doença Relacionada a Imunoglobulina G4 , Humanos , Masculino , Pessoa de Meia-Idade , Colangite Esclerosante/diagnóstico , Colangite Esclerosante/imunologia , Pancreatite Autoimune/diagnóstico , Pancreatite Autoimune/imunologia , Pancreatite Autoimune/tratamento farmacológico , Doença Relacionada a Imunoglobulina G4/diagnóstico , Doença Relacionada a Imunoglobulina G4/complicações , Imunoglobulina G/sangue , Imunoglobulina G/imunologia , Pâncreas/patologia , Pâncreas/diagnóstico por imagem
15.
Chemosphere ; 358: 142109, 2024 Apr 22.
Artigo em Inglês | MEDLINE | ID: mdl-38657692

RESUMO

Recycling polluted water via different techniques has become one of the most feasible ways to solve the freshwater crisis. We describe a novel method to prepare reusable and efficient photothermal energy conversion materials for water purification. Using crosslinked xerogels as precursor, the porous and interconnected carboxymethylcellulose sodium-derived carbon aerogels (abbreviated as CCAs) with good hydrophilic performance and strong light absorption capability are firstly fabricated through pyrolysis. Photothermal measurement results show that CCA15 exhibit excellent solar steam generation rate of 2.31 kg m-2 h-1 with high light-to-vapor conversion efficiency of 95.9% under 1 sun illumination. In addition, the feasible application of CCA15 for efficient water purification under 1 sun irradiation using a homemade water treatment device has been demonstrated successfully. The as-prepared CCAs shown in here can be a continuable solution to mitigate the global freshwater crisis.

16.
Sci Total Environ ; 927: 172014, 2024 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-38547996

RESUMO

Fine-resolution land surface phenology (LSP) is urgently required for applications on agriculture management and vegetation-climate interaction, especially over heterogeneous areas, such as agricultural lands and fragmented forests. The critical challenge of fine-resolution LSP monitoring is how to reconstruct the spatiotemporal continuous vegetation index time series. To solve this problem, various data fusion methods have been devised; however, the comprehensive inter-comparison is lacking across different spatial heterogeneity, data quality, and vegetation types. We divide these methods into two main categories: the change-based methods fusing satellite observations with different spatiotemporal resolutions, and the shape-based methods fusing prior knowledge of shape models and satellite observations. We selected four methods to rebuilt two-band enhanced vegetation index (EVI2) series based on the harmonized Landsat and Sentinel-2 (HLS) data, including two change-based methods, namely the Spatial and temporal Adaptive Reflectance Fusion Model (STARFM), the Flexible Spatiotemporal DAta Fusion (FSDAF), and two shape-based methods, namely the Multiple-year Weighting Shape-Matching (MWSM), and the Spatiotemporal Shape-Matching Model (SSMM). Four phenological transition dates were extracted, evaluated with PhenoCam observations and the 500 m Visible Infrared Imaging Radiometer Suite (VIIRS) phenology product. The 30 m transition dates show more spatial details and reveal more apparent intra-class and inter-class phenology variation compared with 500 m product. The four transition dates of SSMM and FSDAF (R2>0.74, MAD<15 days) show better agreement with PhenoCam-derived dates. The performance difference between fusion methods over various application scenarios are then analyzed. Fusion results are more robust when temporal frequency is higher than 15 observations per year. The shape-based methods are less sensitive to temporal sampling irregularity than change-based methods. Both change-based methods and shape-based methods cannot perform well when the region is heterogeneous. Among different vegetation types, SSMM-like methods have the highest overall accuracy. The findings in this paper can provide references for regional and global fine-resolution phenology monitoring.

17.
Int J Womens Health ; 16: 385-394, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38463688

RESUMO

Objective: This study aimed to evaluate the therapeutic efficacy and safety of Dan'e Fukang soft extracts in moderate ovarian hyperstimulation syndrome (OHSS) for the simultaneous treatment of blood and fluid, guided by the traditional Chinese medicine principle of "triple prevention". Methods: This study conducted a retrospective analysis of clinical data from outpatients who underwent in vitro fertilization (IVF)/intracytoplasmic sperm injection embryo transfer (ICSI-ET). A total of 2245 cases were included and divided into a treatment group (1002 cases) and a control group (1243 cases). Patients in the treatment group were administered Dan'e Fukang soft extracts orally in addition to conventional Western medicine. Comparative assessments were made between the two groups on pelvic ascites volume, maximum ovary diameter, dysmenorrhea incidence post-oocyte retrieval, and safety indicators. Results: There were no statistically significant differences between the treatment group and the control group in terms of general characteristics or the levels of follicle-stimulating hormone (FSH), luteotropic hormone (LH), estradiol (E2), or progesterone (P) at the time of gonadotropin (Gn) initiation. The groups did not differ significantly when we compared the levels of LH, E2, or P on the day of human chorionic gonadotropin (hCG) injection and during ovarian hyperstimulation protocols (P > 0.05 for all indicators). The differences in the volume of pelvic ascites, the maximum ovarian diameter, and the incidence of dysmenorrhea after oocyte retrieval were statistically significant between the treatment group and the control group (P < 0.05 in both). There were no instances of adverse reactions in either group. Conclusion: Based on the traditional Chinese medicine principle of "triple prevention", the use of Dan'e Fukang soft extracts for the simultaneous treatment of blood and fluid in moderate OHSS significantly improved the absorption of pelvic ascites, promoted ovarian recovery, and reduced the incidence of dysmenorrhea after oocyte retrieval.

18.
Ground Water ; 2024 Mar 11.
Artigo em Inglês | MEDLINE | ID: mdl-38465736

RESUMO

The safe operation of underground reservoirs and environmental protection heavily rely on the water flow through coal pillar dams in coal mines. Meanwhile, research on the flow characteristics in coal pillar dams has been limited due to their low hydraulic conductivity. To address this gap, this study assembled a novel seepage experimental device and conducted a series of carefully designed seepage experiments to examine the characteristics of low-permeability in coal pillar dams. The experiments aim to explore the relationship between water flux and hydraulic gradient, considering varying core lengths and immersion times. Flow parameters were determined by fitting observed flux-gradient curves with predictions from both Darcy and non-Darcian laws. Several significant results were obtained. First, a noticeable non-linear relationship between water flux and hydraulic gradient was observed, particularly evident at low flow velocities. Second, the non-Darcy laws effectively interpreted the experimental data, with threshold pressure gradients ranging 13.60 to 58.64 for different core lengths. Third, the study established that water immersion significantly affects the flow characteristics of coal pillar dams, resulting in an increased hydraulic conductivity and flow velocity. These findings carry significant implications for the design of coal pillar dams within underground coal mine reservoirs, providing insights for constructing more stable structures and ensuring environmental protection.

19.
Langmuir ; 40(14): 7384-7394, 2024 Apr 09.
Artigo em Inglês | MEDLINE | ID: mdl-38530344

RESUMO

Photocatalytic technology is a popular research area for converting solar energy into environmentally friendly chemicals and is considered the greenest approach for producing H2O2. However, the corresponding reactive oxygen species (ROS) and pathway involved in the photocatalytic generation of H2O2 by the Bi2.15WO6-glucose system are still not clear. Quenching experiments have established that neither •OH nor h+ contribute to the formation of H2O2, and show that the formed surface superoxo (≡Bi-OO•) and peroxo (≡Bi-OOH) species are the predominant ROS in H2O2 generation. In addition, various characterizations indicate the enhanced electron-transfer on the surface of Bi2.15WO6 with increasing contents of glucose via the ligand-to-metal charge transfer pathway, confirming H-transfer from glucose to ≡Bi-OO• or ≡Bi-OOH. The increased production of H2O2 with decreasing bond dissociation energy (BDEO-H) values of various phenolic compounds again supports the H-transfer mechanism from phenolic compounds to ≡Bi-OO• and then to ≡Bi-OOH. DFT calculations further reveal that on the Bi2.15WO6 surface, oxygen is sequentially reduced to ≡Bi-OO• and ≡Bi-OOH, while H-transfer from H2O or glucose to ≡Bi-OO• and ≡Bi-OOH, resulting in the production of H2O2. The lower energy barrier of H-transfer from adsorbed glucose (0.636 eV) than that from H2O (1.157 eV) indicates that H-transfer is more favorable from adsorbed glucose. This work gives new insight into the photocatalytic generation of H2O2 by Bi2.15WO6 in the presence of glucose/phenolic compounds via the H-abstraction pathway.

20.
Neuroreport ; 35(5): 316-319, 2024 Mar 20.
Artigo em Inglês | MEDLINE | ID: mdl-38407851

RESUMO

OBJECTIVE: Gender differences in pedestrian hazard perception were investigated using the event-related potential technique. METHODS: The study utilized images of two types of real traffic situations as test materials: hazard situations and nonhazard situations. The presence of hazards in the displayed situations was determined by 30 adult subjects (including 17 females), who indicated their observations by pressing a button. RESULTS: The results revealed that females exhibited a shorter N1 latency in hazard situations, while males exhibited a larger P3 amplitude compared to females. CONCLUSION: These results indicate that females are more sensitive to hazard situations during the early visual processing stage, while males give more attention to traffic situations during the late attention allocation stage.


Assuntos
Pedestres , Adulto , Masculino , Feminino , Humanos , Fatores Sexuais , Potenciais Evocados , Percepção Visual , Caracteres Sexuais
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