Prognostic value analysis and survival model construction of different treatment methods for advanced intestinal type gastric adenocarcinoma.

Background: Intestinal-type gastric adenocarcinoma, representing 95 % of gastric malignancies, originates from the malignant transformation of gastric gland cells. Despite its prevalence, existing methods for prognosis evaluation of this cancer subtype are inadequate. This study aims to enhance patient-specific prognosis evaluation by analyzing the clinicopathological characteristics and prognostic risk factors of intestinal-type gastric adenocarcinoma patients using data from the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute (NCI). Methods: We extracted clinical data for patients diagnosed with intestinal-type gastric adenocarcinoma between 2010 and 2015 from the SEER database, selecting 257 cases based on predefined inclusion and exclusion criteria. Independent risk factors for overall survival (OS) and cancer-specific survival (CSS) were identified using a Cox regression model. A nomogram model for predicting OS or CSS was developed from the Cox risk regression analysis and validated through the consistency index (C-index), ROC curve, and calibration curve. Results: Age, primary tumor resection, chemotherapy, lymph node metastasis, and tumor size were identified as independent prognostic factors for OS and CSS (P < 0.05). The nomogram model, constructed from these indicators, demonstrated superior predictive consistency for OS and CSS compared to the AJCC-TNM staging system. ROC curve analysis confirmed the model's higher accuracy, and calibration curve analysis indicated good agreement between the nomogram's predictions and actual observed outcomes. Conclusion: The nomogram model derived from SEER database analyses accurately predicts OS and CSS for patients with intestinal-type gastric adenocarcinoma. This model promises to facilitate more tailored treatments in clinical practice.

Anthropogenic climate change impacts exacerbate summer forest fires in California.

Record-breaking summer forest fires have become a regular occurrence in California. Observations indicate a fivefold increase in summer burned area (BA) in forests in northern and central California during 1996 to 2021 relative to 1971 to 1995. While the higher temperature and increased dryness have been suggested to be the leading causes of increased BA, the extent to which BA changes are due to natural variability or anthropogenic climate change remains unresolved. Here, we develop a climate-driven model of summer BA evolution in California and combine it with natural-only and historical climate simulations to assess the importance of anthropogenic climate change on increased BA. Our results indicate that nearly all the observed increase in BA is due to anthropogenic climate change as historical model simulations accounting for anthropogenic forcing yield 172% (range 84 to 310%) more area burned than simulations with natural forcing only. We detect the signal of combined historical forcing on the observed BA emerging in 2001 with no detectable influence of the natural forcing alone. In addition, even when considering fuel limitations from fire-fuel feedbacks, a 3 to 52% increase in BA relative to the last decades is expected in the next decades (2031 to 2050), highlighting the need for proactive adaptations.

A Review of Computer Vision-Based Structural Deformation Monitoring in Field Environments.

Computer vision-based structural deformation monitoring techniques were studied in a large number of applications in the field of structural health monitoring (SHM). Numerous laboratory tests and short-term field applications contributed to the formation of the basic framework of computer vision deformation monitoring systems towards developing long-term stable monitoring in field environments. The major contribution of this paper was to analyze the influence mechanism of the measuring accuracy of computer vision deformation monitoring systems from two perspectives, the physical impact, and target tracking algorithm impact, and provide the existing solutions. Physical impact included the hardware impact and the environmental impact, while the target tracking algorithm impact included image preprocessing, measurement efficiency and accuracy. The applicability and limitations of computer vision monitoring algorithms were summarized.

Data Loss Reconstruction Method for a Bridge Weigh-in-Motion System Using Generative Adversarial Networks.

In the application of a bridge weigh-in-motion (WIM) system, the collected data may be temporarily or permanently lost due to sensor failure or system transmission failure. The high data loss rate weakens the distribution characteristics of the collected data and the ability of the monitoring system to conduct assessments on bridge condition. A deep learning-based model, or generative adversarial network (GAN), is proposed to reconstruct the missing data in the bridge WIM systems. The proposed GAN in this study can model the collected dataset and predict the missing data. Firstly, the data from stable measurements before the data loss are provided, and then the generator is trained to extract the retained features from the dataset and the data lost in the process are collected by using only the responses of the remaining functional sensors. The discriminator feeds back the recognition results to the generator in order to improve its reconstruction accuracy. In the model training, two loss functions, generation loss and confrontation loss, are used, and the general outline and potential distribution characteristics of the signal are well processed by the model. Finally, by applying the engineering data of the Hangzhou Jiangdong Bridge to the GAN model, this paper verifies the effectiveness of the proposed method. The results show that the final reconstructed dataset is in good agreement with the actual dataset in terms of total vehicle weight and axle weight. Furthermore, the approximate contour and potential distribution characteristics of the original dataset are reproduced. It is suggested that the proposed method can be used in real-life applications. This research can provide a promising method for the data reconstruction of bridge monitoring systems.

Quantifying contributions of natural variability and anthropogenic forcings on increased fire weather risk over the western United States.

Previous studies have identified a recent increase in wildfire activity in the western United States (WUS). However, the extent to which this trend is due to weather pattern changes dominated by natural variability versus anthropogenic warming has been unclear. Using an ensemble constructed flow analogue approach, we have employed observations to estimate vapor pressure deficit (VPD), the leading meteorological variable that controls wildfires, associated with different atmospheric circulation patterns. Our results show that for the period 1979 to 2020, variation in the atmospheric circulation explains, on average, only 32% of the observed VPD trend of 0.48 ± 0.25 hPa/decade (95% CI) over the WUS during the warm season (May to September). The remaining 68% of the upward VPD trend is likely due to anthropogenic warming. The ensemble simulations of climate models participating in the sixth phase of the Coupled Model Intercomparison Project suggest that anthropogenic forcing explains an even larger fraction of the observed VPD trend (88%) for the same period and region. These models and observational estimates likely provide a lower and an upper bound on the true impact of anthropogenic warming on the VPD trend over the WUS. During August 2020, when the August Complex "Gigafire" occurred in the WUS, anthropogenic warming likely explains 50% of the unprecedented high VPD anomalies.