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Am J Trop Med Hyg ; 105(3): 564-572, 2021 06 28.
Artigo em Inglês | MEDLINE | ID: mdl-34181579

RESUMO

Reports on tropical infections among kidney transplant (KT) recipients have increased in recent years, mainly because of the growing number of KT programs located in tropical and subtropical areas, and greater mobility or migration between different areas of the world. Endemic in emerging and developing regions, like most countries in Latin America, tropical infections are an important cause of morbidity and mortality in this population. Tropical infections in KT recipients may exhibit different pathways for acquisition compared with those in nonrecipients, such as transmission through a graft and reactivation of a latent infection triggered by immunosuppression. Clinical presentation may differ compared with that in immunocompetent patients, and there are also particularities in diagnostic aspects, treatment, and prognosis. KT patients must be screened for latent infections and immunized properly. Last, drug-drug interactions between immunosuppressive agents and drugs used to treat tropical infections are an additional challenge in KT patients. In this review, we summarize the management of tropical infections in KT patients.


Assuntos
Infecções por Arbovirus/diagnóstico , Doença de Chagas/diagnóstico , Transplante de Rim , Leishmaniose/diagnóstico , Estrongiloidíase/diagnóstico , Tuberculose/diagnóstico , Infecções por Arbovirus/imunologia , Infecções por Arbovirus/terapia , Doença de Chagas/imunologia , Doença de Chagas/terapia , Febre de Chikungunya/diagnóstico , Febre de Chikungunya/imunologia , Febre de Chikungunya/terapia , Dengue/diagnóstico , Dengue/imunologia , Dengue/terapia , Rejeição de Enxerto/prevenção & controle , Humanos , Hospedeiro Imunocomprometido , Imunossupressores/uso terapêutico , América Latina , Leishmaniose/imunologia , Leishmaniose/terapia , Estrongiloidíase/imunologia , Estrongiloidíase/terapia , Tuberculose/imunologia , Tuberculose/terapia , Febre Amarela/diagnóstico , Febre Amarela/imunologia , Febre Amarela/terapia , Infecção por Zika virus/diagnóstico , Infecção por Zika virus/imunologia , Infecção por Zika virus/terapia
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