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1.
Arq. bras. med. vet. zootec. (Online) ; 74(3): 412-418, May-June 2022. tab, ilus
Artigo em Inglês | VETINDEX | ID: biblio-1383769

RESUMO

This retrospective case series study describes the clinical and vascular ultrasound findings of 26 dogs diagnosed with abdominal thrombosis. Images were selected based on the detection of intravascular echogenic thrombus or the absence of vascular flow on color Doppler, confirmed by surgery or necropsy. Images were acquired using the Mylab 40 model, with linear and microconvex multifrequency probes. All the reports were evaluated along with the corresponding images by a veterinary diagnostic imaging radiologist. The ultrasonographic aspects evaluated were echogenicity (92.3%), anechogenicity (7.7%), vascularization (11.5%), mineralization (15.4%), and recanalization (7.7%) of the thrombosis. The vascular and hemodynamic findings were dilation of the affected vein (57.7%), total occlusion of blood flow (30.8%), presence of turbulent flow (65.38%), and visualization of smoke signal (blood flow detected as moving echogenic points in dynamic bidimensional mode) (11.5%). Neoplasms (19 cases) and nephropathies (13 cases) were the most common clinical conditions in the affected dogs. Eleven cases of vascular invasion due to adrenal neoplasms were identified. The results indicate that the vascular ultrasound examination is an important method for diagnosis, as 23 of the 26 cases did not show any clinical signs of thrombosis.


Este estudo de série de casos retrospectivos descreve os achados clínicos e ultrassonográficos vasculares de 26 cães diagnosticados com trombose. As imagens foram selecionadas baseadas na detecção de trombo ecogênico intravascular ou na ausência de fluxo vascular ao Doppler colorido, confirmado por cirurgia ou necropsia. O equipamento utilizado na aquisição das imagens foi o modelo Mylab 40, com probes multifrequenciais linear e microconvexa. Todos os relatórios foram avaliados com as imagens correspondentes por um veterinário radiologista. As características ultrassonográficas avaliadas foram: ecogenicidade (92,3%), anecogenicidade (7,7%), vascularização (11,5%), mineralização (15,4%) e recanalização (7,7%) das tromboses. Os achados vasculares e hemodinâmicos observados foram: dilatação da veia afetada (57,7%), oclusão total do fluxo sanguíneo (30,8%), presença de fluxo turbulento (65,38%) e visibilização do sinal de fumaça (fluxo vascular visível como pontos ecogênicos em modo bidimensional dinâmico) (11,5%). As neoplasias (19 casos) e as nefropatias (13 casos) foram as condições clínicas mais comuns nos cães afetados. Foram identificados 11 casos de invasão vascular decorrentes de neoplasia de adrenais. Os resultados indicaram que o exame ultrassonográfico vascular é um método importante para diagnóstico, considerando-se que, em 23 casos, não ocorreram sinais clínicos determinantes de trombose.


Assuntos
Animais , Cães , Trombose , Doenças do Cão/diagnóstico por imagem , Nefropatias , Neoplasias
2.
Arq. bras. med. vet. zootec. (Online) ; 72(4): 1271-1276, July-Aug. 2020. tab, ilus
Artigo em Inglês | VETINDEX | ID: vti-30237

RESUMO

The objective of this study was to calculate the collapsibility index (CI) in a group of 15 healthy adult mixed breed cats via right hepatic intercostal ultrasound view. The minimal and the maximal diameters of the caudal vena cava (CVC) were obtained during inspiration and expiration, respectively, then CI was calculated. The mean diameter of the CVC was 0.5cm. The mean CI was 28±3% and CI was not significantly associated with gender. As in human medicine, there is a growing need for less invasive monitoring in small animal practice. The CI enables the assessment of estimated volemia without the need for a central venous catheter. This is the first reported study investigating CI in cats.(AU)


O objetivo deste estudo foi calcular o índice de colapsabilidade (IC) em um grupo de 15 gatos adultos, saudáveis e SRD, por meio da janela ultrassonográfica hepática intercostal direita. Os diâmetros mínimo e máximo da veia cava caudal (VCC) foram obtidos durante a inspiração e a expiração, respectivamente. O IC foi calculado, posteriormente. O diâmetro médio da VCC foi de 0,5cm. O diâmetro médio do IC foi de 28±3%, e o IC não foi significativamente associado ao gênero. Como na medicina humana, há uma necessidade crescente de monitoramento menos invasivo na prática de pequenos animais. O IC possibilita a avaliação da volemia estimada sem a necessidade de um cateter venoso central. Este é o primeiro estudo relatado sobre IC em gatos domésticos.(AU)


Assuntos
Animais , Gatos , Veias Cavas/anatomia & histologia , Pressão Venosa Central/fisiologia , Ultrassonografia
3.
Arq. bras. med. vet. zootec. (Online) ; 72(4): 1271-1276, July-Aug. 2020. tab, ilus
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1131521

RESUMO

The objective of this study was to calculate the collapsibility index (CI) in a group of 15 healthy adult mixed breed cats via right hepatic intercostal ultrasound view. The minimal and the maximal diameters of the caudal vena cava (CVC) were obtained during inspiration and expiration, respectively, then CI was calculated. The mean diameter of the CVC was 0.5cm. The mean CI was 28±3% and CI was not significantly associated with gender. As in human medicine, there is a growing need for less invasive monitoring in small animal practice. The CI enables the assessment of estimated volemia without the need for a central venous catheter. This is the first reported study investigating CI in cats.(AU)


O objetivo deste estudo foi calcular o índice de colapsabilidade (IC) em um grupo de 15 gatos adultos, saudáveis e SRD, por meio da janela ultrassonográfica hepática intercostal direita. Os diâmetros mínimo e máximo da veia cava caudal (VCC) foram obtidos durante a inspiração e a expiração, respectivamente. O IC foi calculado, posteriormente. O diâmetro médio da VCC foi de 0,5cm. O diâmetro médio do IC foi de 28±3%, e o IC não foi significativamente associado ao gênero. Como na medicina humana, há uma necessidade crescente de monitoramento menos invasivo na prática de pequenos animais. O IC possibilita a avaliação da volemia estimada sem a necessidade de um cateter venoso central. Este é o primeiro estudo relatado sobre IC em gatos domésticos.(AU)


Assuntos
Animais , Gatos , Veias Cavas/anatomia & histologia , Pressão Venosa Central/fisiologia , Ultrassonografia
4.
R. bras. Reprod. Anim. ; 44(2): 50-56, abr.-jun. 2020. ilus
Artigo em Português | VETINDEX | ID: vti-28772

RESUMO

A ultrassonografia gestacional em pequenos animais permite, além da confirmação e do monitoramento da prenhez, a detecção precoce de malformações e anormalidades fetais, representando uma importante ferramenta de acompanhamento pré-natal. Médicos veterinários, tutores e criadores podem beneficiar-se deste diagnóstico, uma vez que o conhecimento prévio de anormalidades fetais que exigem cirurgia ou intervenções neonatais permite o planejamento adequado por parte destes indivíduos. Na medicina humana, a detecção precoce de anormalidades fetais já é amplamente empregada no planejamento da conduta em relação à gestante e ao feto antes e após o nascimento. Em medicina veterinária, apesar de escassos, há relatos de malformações fetais diagnosticadas ao exame ultrassonográfico gestacional em pequenos animais. Entretanto, limitações inerentes ao aparelho, ao operador e à anatomia animal podem limitar o diagnóstico na totalidade dos exames, levando à ocorrência de diagnósticos falso-positivos e falso-negativos.(AU)


Gestational ultrasonography in small animals allows, in addition to the confirmation and monitoring of pregnancy, the early detection of malformations and fetal abnormalities, representing an important prenatal monitoring tool. Veterinarians, owners and breeders may benefit from this diagnosis, since prior knowledge of fetal abnormalities that require surgery or neonatal interventions allows adequate planning for these individuals. In human medicine, the early detection of fetal abnormalities is already widely used in planning the conduct in relation to the pregnant woman and the fetus before and after birth. In veterinary medicine, although there are few, there are reports of fetal malformations diagnosed at the ultrasound gestational examination in small animals. However, limitations inherent in the device, the operator and the animal anatomy may limit the diagnosis in all the exams, leading to the occurrence of false positive and false-negative diagnoses.(AU)


Assuntos
Animais , Gatos , Cães , Cães , Gatos , Ultrassonografia Pré-Natal/veterinária , Feto/anormalidades
5.
J Comp Pathol ; 170: 101-104, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31375153

RESUMO

A rare case of bilateral, primary, obstructive, giant megaureter was found during necropsy examination of an 11-year-old female German shepherd dog. On ultrasound examination and at necropsy examination, both ureters were tortuous and extensively dilated with diameter ranging from 1.86 to 4.8 cm. Both vesicoureteral junctions were obstructed by uroliths. A diagnosis of giant megaureter was established using human parameters since these values are not recognized in animals. The classification of obstructive and primary megaureter was determined because the obstruction was due to uroliths at the vesicoureteral junctions.


Assuntos
Doenças do Cão/patologia , Obstrução Ureteral/veterinária , Urolitíase/veterinária , Animais , Cães , Feminino
6.
J Dent ; 90: 103184, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31465818

RESUMO

OBJECTIVE: The aim of this split-mouth, randomized, controlled clinical trial was to evaluate the efficacy of resin infiltration in controlling the progression of non-cavitated proximal lesions in primary molars after two-years follow-up. METHODS: Fifty healthy children presenting at least two primary molars with proximal lesion detected radiographically (in the inner half of enamel or the outer third of dentin) were included in the study. The proximal lesions were randomly allocated into resin infltration + flossing (test group) or flossing (control group). All patients received oral hygiene instructions for daily brushing with fluoride toothpaste (1100 ppmF) and flossing. The proportion of caries progression was compared using the McNemar test. The main outcome after 2-years, caries progression in the radiography was assessed by pair-wise reading by an independent examiner who was blind regarding the treatment. RESULTS: The sample comprised 28 (56%) girls and 22 (44%) boys with a defs of 7,3 (SD = 6,5), mainly of moderate (46%) to high (48%) caries risk. Results after one year were published previously. After 2-years, 29 (58%) patients were assessed. Caries progression was observed in 24.1% (7/29) of the test lesions, compared with 55.2% (16/29) of the control lesions (p = 0.012). The therapeutic effect was 31.1% and the relative risk reduction (RRR) was 56.3%. Eigth lesions from the control group and two lesions from the test group progressed to the inner third of dentin and were restored. CONCLUSIONS: In conclusion, resin infiltration was more efficacious in controlling proximal caries lesions in primary molars than non-invasive approach alone. CLINICAL SIGNIFICANCE: The results indicate that resin infiltration was an efficacious method in controlling proximal caries lesions in primary molars after 2 years, even in patients with high caries risk, reaffirming the results of 1-year follow-up.


Assuntos
Cárie Dentária/tratamento farmacológico , Resinas Sintéticas/uso terapêutico , Dente Decíduo , Cariostáticos/uso terapêutico , Criança , Cárie Dentária/prevenção & controle , Esmalte Dentário/patologia , Feminino , Seguimentos , Humanos , Masculino , Dente Molar , Dente Decíduo/efeitos dos fármacos
7.
Ars Vet. ; 35(3): 127-137, 2019. ilus
Artigo em Português | VETINDEX | ID: vti-25862

RESUMO

Nas últimas décadas, foi possível observar grandes avanços tecnológicos no que se refere às novas técnicas de exames por meio de imagens, que se tornou um componente importante e imprescindível no processo de tomada de decisão frente ao diagnóstico de diversas alterações em pacientes veterinários. Tais exames, cada um com sua especificidade, requerem análise cuidadosa por parte do avaliador e, evidentemente, um bom período de treinamento com o propósito de se extrair o máximo de informação possível que o exame possa oferecer. Mesmo assim, costumam ocorrer situações que geram dúvidas e equívocos, resultando em erros de interpretação. São, na verdade, armadilhas resultantes das próprias limitações da técnica ou da produção dos chamados artefatos, capazes de gerar dúvidas e erros de interpretação, muitas vezes comprometendo a formulação do diagnóstico. Diante do exposto, procurou-se, com este estudo, chamar a atenção dos envolvidos com diagnóstico por imagem em veterinária quanto aos riscos de interpretação, em particular na radiologia e na ultrassonografia, duas técnicas distintas e amplamente usadas na medicina veterinária. Foram selecionadas imagens radiográficas e ultrassonográficas obtidas da rotina de atendimento a pequenos animais do Hospital Veterinário da Escola de Veterinária da Universidade Federal de Minas Gerais (UFMG) que pudessem exemplificar as mais frequentes dúvidas no momento da interpretação e que poderiam induzir a erros. (AU)


In recent decades there have been many great technological advances. Im particular new imaging examination techiniques have becane, important and indispensable component the diagnostic decisiun making process for several alterations in veterinary patients. These examinations, require careful analysis by the examiner and, extensive. In order to extract as much information as possible fron the exam. Even so, situations that generate doubts and confusions occur often, resulting in errors of interpretation. These are, traps result from the limitations of the technique henselves or the production of artifacts, which are of creating doubts and errors of interpretation, this compromisi the diagnosis. In light of this, we sought to draw the attention of those involved in veterinary diagnostic imaging, regarding the risks of misinterpretation, with radiology and ultrasonography, two different techniques widely used in veterinary medicine. Radiographic and ultrasonographic images were obtained from routine small animal care at the Veterinary Hospital of the Federal University of Minas Gerais Veterinary School (UFMG). which demostrate the most frequent doubts during image interpretation and that could potentially induce erros were selected. Situations that could generateperceptual erros were observed. These errosrs could possibly be associated with cognitive erros.(AU)


Assuntos
Animais , Gatos , Cães , Radiografia/veterinária , Interpretação de Imagem Radiográfica Assistida por Computador , Ultrassonografia/veterinária , Diagnóstico por Imagem/veterinária
8.
Ars vet ; 35(3): 127-137, 2019.
Artigo em Português | VETINDEX | ID: vti-765111

RESUMO

Nas últimas décadas, foi possível observar grandes avanços tecnológicos no que se refere às novas técnicas de exames por meio de imagens, que se tornou um componente importante e imprescindível no processo de tomada de decisão frente ao diagnóstico de diversas alterações em pacientes veterinários. Tais exames, cada um com sua especificidade, requerem análise cuidadosa por parte do avaliador e, evidentemente, um bom período de treinamento com o propósito de se extrair o máximo de informação possível que o exame possa oferecer. Mesmo assim, costumam ocorrer situações que geram dúvidas e equívocos, resultando em erros de interpretação. São, na verdade, armadilhas resultantes das próprias limitações da técnica ou da produção dos chamados artefatos, capazes de gerar dúvidas e erros de interpretação, muitas vezes comprometendo a formulação do diagnóstico. Diante do exposto, procurou-se, com este estudo, chamar a atenção dos envolvidos com diagnóstico por imagem em veterinária quanto aos riscos de interpretação, em particular na radiologia e na ultrassonografia, duas técnicas distintas e amplamente usadas na medicina veterinária. Foram selecionadas imagens radiográficas e ultrassonográficas obtidas da rotina de atendimento a pequenos animais do Hospital Veterinário da Escola de Veterinária da Universidade Federal de Minas Gerais (UFMG) que pudessem exemplificar as mais frequentes dúvi

9.
Clin Oral Investig ; 22(3): 1355-1362, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28990122

RESUMO

OBJECTIVE: The main purpose of this split month, randomized, controlled clinical trial was evaluate the efficacy of caries infiltration in controlling the progression of non-cavitated proximal lesions in primary molars. Anxiety and time required for the caries infiltration was also evaluated. MATERIALS AND METHODS: Fifty healthy children, 5 to 9 years, presenting two primary molars with proximal caries lesions (1/2 of the enamel or outer 1/3 of dentin), were included. Lesions were randomly allocated to the test group (fluoridated toothpaste + flossing + infiltration) or to the control group (fluoridated toothpaste + flossing). Caries risk was based on the Cariogram model. The main outcome after 1-year radiographic follow up was assessed by an independent blinded examiner A facial image scale (FIS) was applied to assess dental anxiety and time required to perform the infiltration was recorded. RESULTS: Of the sample, 92.9% corresponded to high or medium caries risk. In 42 patients (1-year follow up), caries progression was observed in 11.9% (5/42) of the test lesions compared with 33.3% (14/42) of the control lesions (p < 0.05). Five control and three test lesions progressed to the middle 1/3 of dentin and were restored. No side effects were observed. Anxiety was both low before and after the treatment, and mean time required for the infiltration was 11.29 min (± 1.16 min). CONCLUSIONS: Caries infiltration of proximal caries lesions in primary molars is significantly more efficacious than standard therapy alone (fluoride toothpaste + flossing). CLINICAL RELEVANCE: Caries infiltration is an applicable and well-accepted method be used in children, representing a promising micro-invasive approach.


Assuntos
Cárie Dentária/terapia , Resinas Sintéticas/uso terapêutico , Cariostáticos/uso terapêutico , Criança , Pré-Escolar , Cárie Dentária/diagnóstico por imagem , Progressão da Doença , Feminino , Fluoretos Tópicos/uso terapêutico , Seguimentos , Humanos , Masculino , Dente Molar , Dente Decíduo
10.
J Clin Pediatr Dent ; 39(2): 124-7, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25823481

RESUMO

OBJECTIVE: Evaluate the presence of a titanium dioxide layer after application of titanium tetrafluoride on human permanent tooth enamel. STUDY DESIGN: The sample consisted of unerupted third molars. After the removal of the roots, each tooth was mesiodistally divided into 2 fragments, one reserved for the experimental group and the other for the control group. Before the treatments the fragments were artificially demineralized. The experimental group (n=5) received an application of 4% titanium tetrafluoride, for one minute and the control group (n=5) did not receive any treatment. The samples were sputter-coated with a 20-30nm gold layer as the energy dispersive x-ray spectrometer analysis was carried out in a scanning electron microscope and the results were descriptively analyzed. RESULTS: The titanium dioxide layer was present on all experimental samples with a titanium peak varying between 6.82 and 26.37%. This layer was not found in the control group. Fluoride and calcium fluoride precipitates were present in the samples treated with titanium tetrafluoride. CONCLUSION: Titanium dioxide layer was formed after one titanium tetrafluoride application, but it was not uniform. Further studies should be carried out so that both the morphology and thickness of such layers can be better understood.


Assuntos
Cariostáticos/farmacologia , Esmalte Dentário/efeitos dos fármacos , Fluoretos/farmacologia , Titânio/farmacologia , Desmineralização do Dente/patologia , Fluoreto de Cálcio/análise , Cariostáticos/análise , Esmalte Dentário/química , Fluoretos/análise , Humanos , Microscopia Eletrônica de Varredura , Espectrometria por Raios X , Titânio/análise
11.
Eur J Paediatr Dent ; 12(2): 75-80, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21668275

RESUMO

AIM: Oral manifestations are common in HIV+ children, but the impact of these diseases on their daily life is unknown. So the aim of this study was to assess the impact of oral problems on the daily activities of HIV+ children. METHODS: The Child-OIDP-B was used with 59 10-12 year-old HIV+ children, who were outpatients at two public hospitals for HIV treatment in Rio de Janeiro, Brazil. Caries, biofilm and gingival bleeding indexes were recorded. The Kruskall-Wallis and Mann-Whitney tests as well as the Spearman's correlation coefficient were used for analysis. Statistical evaluation: Replies were analysed using the Statgraphics ® Plus Version 5.0 statistics software system, in order to obtain comparative diagrams and graphs using the ANOVA multifactorial system. RESULTS: The Child-OIDP-B scores ranged from 0 to 30, (mean=6.09) and 71.2% of the children were affected by oral problems. Association was found between oral impact and number of caries (p=0.009). Children receiving HAART therapy had a Child-OIDP-B score (4.87), much lower than those who were not (8.87) (p=0.038). The most reported oral impact of the disease was eating (55.6%), but oral wounds were the most prevalent type of lesions (76.3%). As regards the level of intensity of the impact, moderate severity was prevalent in all 59 children and 66.1% reported that oral impacts affected 1-4 daily activities, 50.8% of all children were not satisfied with their appearance and oral health; 23.7% perceived the impact of HIV-infection on general health. CONCLUSION: Most children suffered the impact of oral problems on their daily activities, mainly functional impacts.


Assuntos
Atividades Cotidianas , Infecções por HIV/psicologia , Doenças da Boca/psicologia , Qualidade de Vida , Doenças Dentárias/psicologia , Terapia Antirretroviral de Alta Atividade , Atitude Frente a Saúde , Biofilmes , Criança , Índice CPO , Cárie Dentária/psicologia , Ingestão de Alimentos/fisiologia , Emoções , Feminino , Hemorragia Gengival/psicologia , Infecções por HIV/complicações , Soropositividade para HIV/psicologia , Nível de Saúde , Humanos , Relações Interpessoais , Masculino , Doenças da Boca/complicações , Saúde Bucal , Índice Periodontal , Satisfação Pessoal , Sono/fisiologia , Sorriso/fisiologia , Fala/fisiologia , Doenças Dentárias/complicações , Escovação Dentária
12.
Eur J Paediatr Dent ; 12(2): 81-6, 2011 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-21668276

RESUMO

AIM: The objective was to assess the impact of oral health on the quality of life of HIV-infected patients aged 3-6 years based on their caregivers' perceptions. METHODS: A questionnaire for measuring the perception and the instrument Early Childhood Oral Health Impact Scale (ECOHIS) were applied to 31 caregivers whose children were being treated in a public hospital. Results The mean age of the children was 4.52 years (SD 1.22). The total ECOHIS score ranged from 0 to 26, with a mean value of 4.13 (SD 6.66). Seventeen children (54.8%) were found to have at least one impact: toothache (64.7%), herpetic gingivostomatitis (23.5%) or both (11.8%). Statistically significant difference was found between the ECOHIS score and presence of restored teeth, prior dental treatment, AIDS, and viral load. With respect to the caregivers' perception, it resulted to be adequate, as those caregivers whose children had a greater number of decayed teeth and higher biofilm index also considered the oral health to be bad (P<0.001). However, the children's general health was found to be good despite the worse immunological classification (P<0.017).Conclusion The quality of life of the HIV- infected children has been negatively affected by the oral health.


Assuntos
Infecções por HIV/psicologia , Soropositividade para HIV/psicologia , Saúde Bucal , Qualidade de Vida , Síndrome de Imunodeficiência Adquirida/psicologia , Síndrome de Imunodeficiência Adquirida/virologia , Adulto , Atitude Frente a Saúde , Biofilmes , Cuidadores/psicologia , Criança , Pré-Escolar , Índice CPO , Assistência Odontológica/psicologia , Cárie Dentária/psicologia , Índice de Placa Dentária , Restauração Dentária Permanente/psicologia , Feminino , HIV/isolamento & purificação , Infecções por HIV/virologia , Soropositividade para HIV/virologia , Nível de Saúde , Humanos , Masculino , Mordida Aberta , Estomatite Herpética/psicologia , Descoloração de Dente/psicologia , Perda de Dente/psicologia , Odontalgia/psicologia , Carga Viral
13.
Oral Dis ; 16(5): 431-7, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20233327

RESUMO

OBJECTIVE: This study describes the expression of acidic ectophosphatase activity on twenty isolates of C. albicans from oral cavities of HIV-infected children (HIV+) and compares them with fifteen isolates from HIV-negative children (HIV-), as well as the fungal adhesion to epithelial cells and medical records. METHODS: The activities were measured in intact cells grown in BHI medium for 48 h at 37 degrees C. Phosphatase activity was assayed at pH 5.5 using 4-methylumbelliferyl phosphate. Yeast adhesion was measured using the MA 104 epithelial cell line. RESULTS: Mean values of ectophosphatase activity were 610.27 +/- 166.36 and 241.25 +/- 78.96 picomoles 4-methylumbelliferone/h/10(7) cells for HIV+ and HIV- group, respectively (P = 0.049). No correlation between C. albicans enzyme activity from HIV children with viral load and CD4 percentual was observed. Yeasts with high enzyme activity, isolated from HIV+ children showed greater adherence than yeasts with basal levels of ectophosphatases from HIV- (Spearman correlation, r = 0.8). Surface phosphatase activity was apparently involved in the adhesion to host cells, as the enhanced attachment of C. albicans to host epithelial cells was reversed by pretreatment of yeast with sodium orthovanadate (1 mM), an acid phosphatase inhibitor. CONCLUSION: These results show that C. albicans from HIV+ has an ectophosphatase activity significantly higher than the other isolates. Yeasts expressing higher levels of surface phosphatase activity showed greater adhesion to epithelial cells. So, the activity of acidic surface phosphatases on these cells may contribute to the early mechanisms required for disease establishment.


Assuntos
Fosfatase Ácida/metabolismo , Candida albicans/enzimologia , Soronegatividade para HIV , Soropositividade para HIV/microbiologia , Fosfatase Ácida/antagonistas & inibidores , Animais , Contagem de Linfócito CD4 , Adesão Celular/efeitos dos fármacos , Adesão Celular/fisiologia , Linhagem Celular , Criança , Inibidores Enzimáticos/farmacologia , Células Epiteliais/microbiologia , HIV/isolamento & purificação , Soropositividade para HIV/virologia , Humanos , Concentração de Íons de Hidrogênio , Himecromona/análogos & derivados , Indicadores e Reagentes , Mucosa Bucal/microbiologia , Mucosa Bucal/patologia , Vanadatos/farmacologia , Carga Viral
14.
J Indian Soc Pedod Prev Dent ; 26 Suppl 1: S23-5, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18974541

RESUMO

Pyknodysostosis is a rare, genetic, autosomal recessive condition characterized by short stature, generalized bone sclerosis, and oral manifestations such as maxillary atresia and an increase of the mandibular angle. The main purpose of this article was to report a case of pyknodysostosis, describing the characteristic orofacial findings of the disease and discussing the differential diagnosis.


Assuntos
Assistência Odontológica para Doentes Crônicos , Anormalidades Maxilomandibulares/etiologia , Má Oclusão/etiologia , Picnodisostose/complicações , Cefalometria , Criança , Transtornos de Deglutição/etiologia , Diagnóstico Diferencial , Feminino , Gengivite/complicações , Humanos , Respiração Bucal/etiologia , Mordida Aberta/etiologia , Picnodisostose/patologia
15.
Community Dent Health ; 25(3): 170-2, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18839724

RESUMO

OBJECTIVE: The aim of this work was to analyze pH and sugar concentration in seven antiretroviral and three antibacterial medications frequently prescribed to HIV infected paediatric patients. METHOD: Sugars (sucrose, glucose, lactose and fructose) and pH were measured from every one of ten medications with different serial numbers in two samples. The pH was determined by a previously calibrated digital pHmeter (Beckman). Analysis of free sugars was performed using thin-layer chromatography (TLC). The pH results and the amount of sugar originated from the two samples in each lot were added. The arithmetic mean of these results were computed. RESULTS: Two antiretrovirals (Zidovudin and Abacavir Sulphate) had pH below critical level (3.55 and 3.93, respectively). All three antibacterials analyzed had pH above 5.5, and one of them (Azithromycin) had the highest pH level of the ten medications examined (9.28). Sugar was present in seven out of 10 of the medications analyzed. The antibacterials contained the highest concentration of sucrose, ranging from 40% to 54%. Glucose was found in one of the ten, sucrose was present in seven of them and none showed lactose. Fructose was not observed with the technique used. CONCLUSIONS: A number of medications frequently used by HIV-infected children may cause a significant risk of both caries and dental erosion.


Assuntos
Fármacos Anti-HIV/efeitos adversos , Cariogênicos/efeitos adversos , Cárie Dentária/induzido quimicamente , Infecções por HIV/tratamento farmacológico , Sacarose/efeitos adversos , Erosão Dentária/induzido quimicamente , Amoxicilina/efeitos adversos , Amoxicilina/análise , Antibacterianos/efeitos adversos , Antibacterianos/análise , Fármacos Anti-HIV/análise , Azitromicina/efeitos adversos , Azitromicina/análise , Cariogênicos/análise , Cromatografia em Camada Delgada , Didesoxinucleosídeos/efeitos adversos , Didesoxinucleosídeos/análise , Frutose/efeitos adversos , Frutose/análise , Glucose/efeitos adversos , Glucose/análise , Humanos , Concentração de Íons de Hidrogênio , Lactose/efeitos adversos , Lactose/análise , Sacarose/análise , Zidovudina/efeitos adversos , Zidovudina/análise
16.
Dentomaxillofac Radiol ; 37(1): 34-9, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18195253

RESUMO

OBJECTIVES: To determine the intra- and interexaminer reliability of two methods (calliper and computerized images) for measuring the alveolar bone level on bitewing radiographs of pre-school children and to determine the extent to which one method can measure more sites. METHODS: Standardized paediatric bitewings were analysed with either an image analysis program (ImageTool) or a digital calliper (Digimatic Caliper). With each method, radiographs were measured three times by three trained examiners. The differences in the number of sites measured with the two methods were assessed with McNemar's tests and kappa statistics. Reliability was assessed with paired t-tests, intraclass correlation coefficients (ICCs), Bland-Altman and survival-agreement plots. RESULTS: The kappa statistics and McNemar's test indicated that examiners measured 14% fewer sites using ImageTool. Paired t-tests also demonstrated a statistically significant bias (range 0.11-0.23 mm) indicating larger measurements for this method, although these observed differences were considered clinically unimportant for the detection of 2 mm of bone loss (which was considered the threshold for periodontal disease). Intra- and interexaminer reliability (ICC range: 0.87-0.97) was considered good for both methods. CONCLUSIONS: Reliable methods to assess alveolar bone loss in primary teeth are important for the diagnosis of incipient periodontal diseases. Both studied methods proved to be reliable. With the Digimatic Caliper, however, more sites were measured.


Assuntos
Processo Alveolar/diagnóstico por imagem , Processamento de Imagem Assistida por Computador/métodos , Radiografia Interproximal/normas , Processo Alveolar/anatomia & histologia , Pré-Escolar , Métodos Epidemiológicos , Humanos , Radiografia Interproximal/instrumentação
17.
Rev. bras. ciênc. vet ; 12(1/3): 46-52, jan.-dez. 2005. tab, graf
Artigo em Português | LILACS | ID: lil-435908

RESUMO

O extrato acetato de etila de Spigelia anthelmia (EASa) mostrou formalmente ser altamente eficaz contra o desenvolvimento larvar e a eclosão de ovos de Haemonchus contorlus, um importante parasito de ruminantes, in vitro. A OL, e a OL,o de EASa foram administradas subcrônica e cronicamente pela via oral em ratos wistar e o perfil bioquímico foi comparado antes e após cada tratamento e com veículo. Vários órgãos foram coletados e processados para análise histopatológica. Os parâmetros hematológicos foram avaliados antes e depois da administração de EASa durante 30 dias. E os efeitos do EASa administrado pela via oral durante o período embriogênico ou organogênico a camundongas gestantes foram estudados. Os efeitos diretos de EASa, in vivo, foram calculados na pressão sangüínea arterial média e no eletrocardiograma (ECG), e in vitro no coração isolado e no átrio isolado de ratos. A administração de EASa não afetou qualquer parâmetro bioquímico, hematológico ou reprodutivo estudado. EASa induziu um efeito hipotensivo de curto prazo em ratos normotensivos sem qualquer alteração concomitante nos parâmetros do ECG. As maiores doses de EASa induziram uma significante diminuição da amplitude de contração do coração e átrio direito. EASa é desprovido de toxicidade significante e tem leves efeitos no sistema cardiovascular(


Assuntos
Camundongos , Ratos , Spigelia anthelmia , Toxicologia
19.
Eur J Paediatr Dent ; 6(4): 197-201, 2005 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16426119

RESUMO

AIM: This was to evaluate caries risk factors: medicine consumption level, oral hygiene frequency and oral hygiene habits during hospitalization of children with and without special needs. METHODS: A cross-sectional study was carried out using a pre-tested form, interviews were conducted with guardians of children with (G1-116) and without special needs (G2-86), from a public day nursery in Rio de Janeiro (Brazil). RESULTS: Average use of medications was at 21.8 months for G1--24.5 and G2--7.2 (Mann-Whitney: p-value = 0.0009). In the total sample, medicines were taken usually at night; 8.4% of parents sweetened them before ingestion and the majority of children did not brush their teeth after taking medicines. More than half (61.9%) had been hospitalized with an average duration of 21.8 days; 83 (66.4%) had had few hospitalizations; G1--62.8% and G2--77.4%. Some 81.6% of the sample reported no tooth brushing while in hospital. STATISTICS: The data were entered in the EPI INFO 6.04d program, and the tests used were Fisher Exact, Mann-Whitney, Kruskal-Wallis and Chi-square with a 5% significance level. CONCLUSIONS: Poor oral hygiene habits when taking medicines and during hospitalizations were observed, mainly among children with special needs.


Assuntos
Criança Hospitalizada , Cárie Dentária/etiologia , Crianças com Deficiência , Preparações Farmacêuticas , Sacarose/efeitos adversos , Edulcorantes/efeitos adversos , Administração Oral , Atitude Frente a Saúde , Estudos de Casos e Controles , Criança , Pré-Escolar , Estudos Transversais , Humanos , Lactente , Entrevistas como Assunto , Saúde Bucal , Higiene Bucal , Pais/psicologia , Preparações Farmacêuticas/administração & dosagem , Fatores de Risco , Fatores de Tempo , Escovação Dentária
20.
J Clin Microbiol ; 42(12): 5925-7, 2004 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15583343

RESUMO

The prevalence of subgingival Candida species was studied in 52 human immunodeficiency virus (HIV)-positive and 42 HIV-negative children. Candida was cultured from 22 (42.3%) and 3 (7.1%) HIV-infected and control children, respectively. C. albicans was the most common Candida species isolated from HIV-infected children, followed by C. dubliniensis, C. glabrata, and C. tropicalis. In the HIV-positive group, the prevalence of Candida isolation was significantly higher in children who presented with low CD4(+)-T-lymphocyte counts, elevated viral loads, and gingivitis.


Assuntos
Infecções Oportunistas Relacionadas com a AIDS/microbiologia , Candida/isolamento & purificação , Candidíase Bucal/microbiologia , Gengiva/microbiologia , Gengivite/microbiologia , Infecções por HIV/complicações , Brasil , Contagem de Linfócito CD4 , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Carga Viral
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