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Int J Biol Macromol ; 267(Pt 2): 131172, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38552701

RESUMO

In this study, the impact of acetylation on physicochemical, digestive behavior and fermentation characteristics of Cyperus esculentus polysaccharides (CEP) was investigated. Results indicated that the acetylation led the molecules to be more likely aggregated, followed by a higher crystallinity, a lower apparent viscosity and a higher ratio of G" to G' (tan δ). Importantly, the acetylated polysaccharides (ACEP) had a lower digestibility, but its molecular weight was lower than that of original polysaccharides (CEP) following a simulated saliva-gastrointestinal digestion. Gut microbiota fermentation indicated that both polysaccharides generated outstanding short-chain fatty acids (SCFAs), in which the acetylated polysaccharides had a faster fermentation kinetics than the original one, followed by a quicker reduction of pH and a more accumulation of SCFAs, particularly butyrate. Fermentation of both polysaccharides promoted Akkermansia, followed by a reduced richness of Klebsiella. Importantly, the current study revealed that the fermentation of acetylated polysaccharides enriched Parabacteroides, while fermentation of original ones promoted Bifidobacterium, for indicating their individual fermentation characteristics and gut environmental benefits.


Assuntos
Cyperus , Ácidos Graxos Voláteis , Fermentação , Microbioma Gastrointestinal , Polissacarídeos , Microbioma Gastrointestinal/efeitos dos fármacos , Polissacarídeos/química , Polissacarídeos/farmacologia , Polissacarídeos/metabolismo , Acetilação , Cyperus/química , Ácidos Graxos Voláteis/metabolismo , Fenômenos Químicos , Animais , Viscosidade , Concentração de Íons de Hidrogênio
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