The hidden threat: Environmental toxins and their effects on gut microbiota.

The human gut microbiota (GM), which consists of a complex and diverse ecosystem of bacteria, plays a vital role in overall wellness. However, the delicate balance of this intricate system is being compromised by the widespread presence of environmental toxins. The intricate connection between contaminants in the environment and human well-being has garnered significant attention in recent times. Although many environmental pollutants and their toxicity have been identified and studied in laboratory settings and animal models, there is insufficient data concerning their relevance to human physiology. Consequently, research on the toxicity of environmental toxins in GM has gained prominence in recent years. Various factors, such as air pollution, chemicals, heavy metals, and pesticides, have a detrimental impact on the composition and functioning of the GM. This comprehensive review aims to comprehend the toxic effects of numerous environmental pollutants, including antibiotics, endocrine-disrupting chemicals, heavy metals, and pesticides, on GM by examining recent research findings. The current analysis concludes that different types of environmental toxins can lead to GM dysbiosis and have various potential adverse effects on the well-being of animals. We investigate the alterations to the GM composition induced by contaminants and their impact on overall well-being, providing a fresh perspective on research related to pollutant exposure.

The association between air pollutions and emergency hospitalizations due to COPD and asthma across 16 Polish cities: population-based study.

OBJECTIVES: In recent years numerous initiatives aimed at reducing air pollution have been undertaken in Poland. The general objective was to examine the correlation between air pollution measured by the level of particulate matter ≤10 µm in diameter (PM10) and emergency hospitalizations due to chronic obstructive pulmonary disease (COPD) and asthma in 16 Polish cities (capitals of the regions). MATERIAL AND METHODS: The authors aimed to diagnose the situation across 16 cities over a 5­year period (2014-2019). Data on the number of hospitalizations was retrieved from the national public insurance system, the National Health Fund. A total number of 22 600 emergency hospitalizations was analyzed (12 000 and 10 600 in 2014 and 2019, respectively). The data on air pollution was accessed via the public register of the Chief Inspectorate for Environmental Protection air quality database. The authors of this article have used the data on PM10 daily exposure in each of the 16 cities in 2014 and 2019. Statistical methods included: non-parametric tests, a 2-stage modelling approach for time-series data, and multivariate meta-analysis of the results. RESULTS: The results indicated that there was a statistically significant decrease in PM10 concentration in 2019 in comparison to 2014 in all cities, mainly in the autumn and winter season. However, the correlation between the improvement in the air quality and a decrease in emergency hospitalizations due to asthma and COPD turned out to not be as strong as expected. The authors observed a strong correlation between PM10 concentrations and hospitalizations due to asthma and COPD, but only when air quality norms were significantly above acceptable levels. CONCLUSIONS: Air pollution measured by PM10 concentration might be used as one of the predictors of the asthma and COPD emergency hospitalization risk, yet other factors like respiratory tract infection, health care organizational aspect, patient self-control, compliance and comorbidities should also be taken into consideration. Int J Occup Med Environ Health. 2024;37(1):110-27.

Upcycling air pollutants to fuels and chemicals via electrochemical reduction technology.

The intensification of fossil fuel usage results in significant air pollution levels. Efforts have been put into developing efficient technologies capable of converting air pollution into valuable products, including fuels and valuable chemicals (e.g., CO2 to hydrocarbon and syngas and NOx to ammonia). Among the strategic efforts to mitigate the excessive concentration of CO2 and NOx pollutants in the atmosphere, the electrochemical reduction technology of CO2 (CO2RR) and NOx (NOxRR) emerges as one of the most promising approaches. It is even more attractive if CO2RR and NOxRR are paired with renewables to store intermittent electricity in the form of chemical feedstocks. This review provides an overview of the electrochemical reduction process to convert CO2 to C1 and/or C2+ chemicals and NOx to ammonia (NH3) with a focus on electrocatalysts, electrolytes, electrolyzer, and catalytic reactor designs toward highly selective electrochemical conversion of the desired products. While the attempts in these aspects are enormous, economic consideration and environmental feasibility for actual implementation are not comprehensively provided. We discuss CO2RR and NOxRR from the life cycle and techno-economic analyses to perceive the feasibility of the current achievements. The remaining challenges associated with the industrial implementation of electrochemical CO2 and NOx reduction are additionally provided.

Renewable solar and wind energies on buildings for green ports in Egypt.

Energy management plan is utilized as an optimum strategy by using solar and wind energies, as a new preliminary implementation. The aim of the study is to create an optimum strategy through an optimization of an energy management system. The study implemented an onsite model, two numerical approaches, and an optimization analysis on a Mediterranean port. Two approaches have been used: solar energy is applied experimentally and numerically, and then wind energy is simulated. An optimization analysis integrated the two approaches together to control their operation. The results showed the installed solar panels provided sufficient generated power for the buildings. Also, the simulated wind arrays showed good behavior with increased power coefficient for the wind turbines, for future implementation. These results were validated using the DesignBuilder software and showed accurate values regarding the experiment for solar panels and CFD simulation. Eventually, a Pareto optimality analysis is applied between the solar and wind energies to reveal an energy management plan. Renewable energy offered energy to support the consumption of the port's buildings.

Effective remediation and decontamination of organophosphorus compounds using enzymes: From rational design to potential applications.

Organophosphorus compounds (OPs) have been widely used in agriculture for decades because of their high insecticidal efficiency, which maintains and increases crop yields worldwide. More importantly, OPs, as typical chemical warfare agents, are a serious concern and significant danger for military and civilian personnel. The widespread use of OPs, superfluous and unreasonable use, has caused great harm to the environment and food chain. Developing efficient and environmentally friendly solutions for the decontamination of OPs is a long-term challenge. Microbial enzymes show potential application as natural and green biocatalysts. Thus, utilizing OP-degrading enzymes for environmental decontamination presents significant advantages, as these enzymes can rapidly hydrolyze OPs; are environmentally friendly, nonflammable, and noncorrosive; and can be discarded safely and easily. Here, the properties, structure and catalytic mechanism of various typical OP-degrading enzymes are reviewed. The methods and effects utilized to improve the expression level, catalytic performance and stability of OP-degrading enzymes were systematically summarized. In addition, the immobilization of OP-degrading enzymes was explicated emphatically, and the latest progress of cascade reactions based on immobilized enzymes was discussed. Finally, the latest applications of OP-degrading enzymes were summarized, including biosensors, nanozyme mimics and medical detoxification. This review provides guidance for the future development of OP-degrading enzymes and promotes their application in the field of environmental bioremediation and medicine.

The Impact of Short-Term Outdoor Air Pollution on Clinical Status and Prognosis of Hospitalized Patients with Coronary Artery Disease Treated with Percutaneous Coronary Intervention.

BACKGROUND: The aim of this study was to determine the influence of acute exposure to air pollutants on patients' profile, short- and mid-term outcomes of hospitalized patients with coronary artery disease (CAD) treated with coronary angioplasty. METHODS: Out of 19,582 patients of the TERCET Registry, 7521 patients living in the Upper Silesia and Zaglebie Metropolis were included. The study population was divided into two groups according to the diagnosis of chronic (CCS) or acute coronary syndromes (ACS). Data on 24-h average concentrations of particulate matter with aerodynamic diameter <10 µm (PM10), sulfur dioxide (SO2), nitrogen monoxide (NO), nitrogen dioxide (NO2), and ozone (O3) were obtained from eight environmental monitoring stations. RESULTS: No significant association between pollutants' concentration with baseline characteristic and in-hospital outcomes was observed. In the ACS group at 30 days, exceeding the 3rd quartile of PM10 was associated with almost 2-fold increased risk of adverse events and more than 3-fold increased risk of death. Exceeding the 3rd quartile of SO2 was connected with more than 8-fold increased risk of death at 30 days. In the CCS group, exceeding the 3rd quartile of SO2 was linked to almost 2,5-fold increased risk of 12-month death. CONCLUSIONS: The acute increase in air pollutants' concentrations affect short- and mid-term prognosis in patients with CAD.

Spatiotemporal Analysis for COVID-19 Delta Variant Using GIS-Based Air Parameter and Spatial Modeling.

The coronavirus disease of 2019 (COVID-19) pandemic is currently a global challenge, with 210 countries, including Indonesia, seeking to minimize its spread. Therefore, this study aims to determine the spatiotemporal spread pattern of this virus in Surabaya using various data on confirmed cases from 28 April to 26 October 2021. It also aims to determine the relationship between pollutant parameters, such as carbon monoxide (CO), nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O3), as well as the government's high social restrictions policy in Java-Bali. Several methods, such as the weighted mean center, directional distribution, Getis-Ord Gi*, Moran's I, and geographically weighted regression, were used to identify the spatial spread pattern of the virus. The weighted mean center indicated that the epicenter location of the outbreak moved randomly. The directional distribution demonstrated a decrease of 21 km2 at the end of the study phase, which proved that its spread has significantly reduced in Surabaya. Meanwhile, the Getis-Ord Gi* results demonstrated that the eastern and southern parts of the study region were highly infected. Moran's I demonstrate that COVID-19 cases clustered during the spike. The geographically weighted regression model indicated a number of influence zones in the northeast, northwest, and a few in the southwest parts at the peak of R2 0.55. The relationship between COVID-19 cases and air pollution parameters proved that people living at the outbreak's center have low pollution levels due to lockdown. Furthermore, the lockdown policy reduced CO, NO2, SO2, and O3. In addition, increase in air pollutants; namely, NO2, CO, SO2 and O3, was recorded after 7 weeks of lockdown implementation (started from 18 August).

Heavy metal accumulation characteristics and physiological response of Sabina chinensis and Platycladus orientalis to atmospheric pollution.

Heavy metal (Cu, Mn, Zn, Pb, and Cd) concentrations were measured in the leaves of Sabina chinensis and Platycladus orientalis collected from urban, suburban, and rural sites in Tianjin, China. Photosynthetic pigment contents, reactive oxygen species content, malondialdehyde (MDA) content and antioxidant enzyme activity were investigated, providing physiological response parameters. Our comparison of the sites revealed that urbanization significantly influenced the heavy metal concentrations in both plant leaves. At the rural site, both plant leaves exhibited the lowest heavy metal accumulation. The highest Cu, Mn, and Zn concentrations were found in S. chinensis leaves from the urban site; the highest Pb and Cd concentrations were found in P. orientalis leaves from the urban site. These results indicate that the urban site contained larger heavy metal concentrations in the plant leaves that may reflect the anthropogenic emission gradient. It is also found that S. chinensis may be used to monitor airborne heavy metal pollution because it is highly quick response to heavy metals, while P. orientalis may be used for mitigation due to its high resistance. The results of this study can contribute to the development of monitoring and environmental management plans by providing information on sensitive and resistant tree species for city greening in North China.

Non-Coding RNAs in Airway Diseases: A Brief Overview of Recent Data.

Inflammation of the human lung is mediated in response to different stimuli (e.g., physical, radioactive, infective, pro-allergenic, or toxic) such as cigarette smoke and environmental pollutants. These stimuli often promote an increase in different inflammatory activities in the airways, manifesting themselves as chronic diseases (e.g., allergic airway diseases, asthma chronic bronchitis/chronic obstructive pulmonary disease, or even lung cancer). Non-coding RNA (ncRNAs) are single-stranded RNA molecules of few nucleotides that regulate the gene expression involved in many cellular processes. ncRNA are molecules typically involved in the reduction of translation and stability of the genes of mRNAs s. They regulate many biological aspects such as cellular growth, proliferation, differentiation, regulation of cell cycle, aging, apoptosis, metabolism, and neuronal patterning, and influence a wide range of biologic processes essential for the maintenance of cellular homeostasis. The relevance of ncRNAs in the pathogenetic mechanisms of respiratory diseases has been widely established and in the last decade many papers were published. However, once their importance is established in pathogenetic mechanisms, it becomes important to further deepen the research in this direction. In this review we describe several of most recent knowledge concerning ncRNA (overall miRNAs) expression and activities in the lung.

Assessment of the Railroad Transport Impact on Physical and Chemical Soil Properties: The Case Study from Zdunska Wola Karsznice Railway Junction, Central Poland.

Contamination of the soil and water environment with harmful substances can be associated with many activities carried out on the railway. The problem is particularly relevant to liquid fuel loading and refueling facilities as well as to increased traffic at railway junctions. Studies were conducted in the area of railway junction Zdunska Wola Karsznice in central Poland (Lódz Voivodeship). Soil samples were collected from specific research points: from the inter-railway (A), 5 m from the main track (B), from the embankment-10 m from the main track (C), and from the side track (D), at the depth of 0-5 cm (1) and 20 cm (2). The following analyses were made: granulometric composition, pH in H2O, and percent content of carbonates (CaCO3). PHEs were determined in the fractions: 0.25 ≤ 0.5 mm, 0.1 ≤ 0.25 mm, and 0.05 ≤ 0.1 mm: Pb, Cd, Cr, Co, Cu, Ni, Zn, Sr by inductively coupled plasma mass spectrometry technique (ICP-MS/TOF OPTIMass 9500). The objectives of the study were (1) to assess PHEs (potentially harmful elements) contamination of the topsoil level of railway area, (2) to determine the correlation between the concentration of PHEs and the size of the fraction, and (3) to identify the areas (places) where the highest concentrations of PHEs were recorded. Based on the studied parameters, significant differentiation in soil properties of the areas in Zdunska Wola Karsznice was found. The analyses carried out showed that the accumulation of potentially harmful elements was as follows: Cu > Zn > Sr > Pb > Ni > Cr > Co > Cd. The average concentrations of Cu, Zn, Sr, Pb, Ni, Cr, Co and Cd were 216.0; 152.1; 97.8; 64.6; 15.2; 14.4; 3.1 and 0.2 mg·kg-1 d.w., respectively. These contaminations occur in the topsoil layer of the railway embankment, which suggests a railway transport origin. The highest concentrations of PHEs were recorded in samples collected from close to the rails (inter-railway, side track), and in the embankment (10 m from the track) in the very fine sand fraction (0.05 ≤ 0.1 mm). The high accumulation index of copper, cadmium and lead in the surface layer of soil indicate their anthropogenic origin. The results presented in the paper can be used in local planning and spatial development of this area, taking into account all future decisions about ensuring environmental protection, including groundwater and soils.

Amino-Functionalized Fe3O4@SiO2 Core-Shell Magnetic Nanoparticles for Dye Adsorption.

Fe3O4@SiO2 core-shell nanoparticles (NPs) were synthesized with the co-precipitation method and functionalized with NH2 amino-groups. The nanoparticles were characterized by X-ray, FT-IR spectroscopy, transmission electron microscopy, selected area electron diffraction, and vibrating sample magnetometry. The magnetic core of all the nanoparticles was shown to be nanocrystalline with the crystal parameters corresponding only to the Fe3O4 phase covered with a homogeneous amorphous silica (SiO2) shell of about 6 nm in thickness. The FT-IR spectra confirmed the appearance of chemical bonds at amino functionalization. The magnetic measurements revealed unusually high saturation magnetization of the initial Fe3O4 nanoparticles, which was presumably associated with the deviations in the Fe ion distribution between the tetrahedral and octahedral positions in the nanocrystals as compared to the bulk stoichiometric magnetite. The fluorescent spectrum of eosin Y-doped NPs dispersed in water solution was obtained and a red shift and line broadening (in comparison with the dye molecules being free in water) were revealed and explained. Most attention was paid to the adsorption properties of the nanoparticles with respect to three dyes: methylene blue, Congo red, and eosin Y. The kinetic data showed that the adsorption processes were associated with the pseudo-second order mechanism for all three dyes. The equilibrium data were more compatible with the Langmuir isotherm and the maximum adsorption capacity was reached for Congo red.

Blood lead level and nutritional status indicators in preadolescent Polish schoolchildren.

BACKGROUND: Environmental pollutions with heavy metals may have toxic effects on human health and development. One of the most detrimental is lead exposure, which may disturb neurodevelopment and linear growth in children. However, data on the effect of lead exposure on nutritional and weight status in children are limited, thus this study aimed to assess the effect of blood lead (Pb) level on nutritional and weight status in preadolescent schoolchildren from the industrialized, mining region in southwestern Poland. METHODS: Our study sample involved N = 709 schoolchildren (402 boys and 307 girls) in the preadolescent developmental period (7-11 years of age for boys and 7-10 years of age for girls). Anthropometric measurements were used to assess nutritional and weight status: body mass index (BMI), mid-upper arm circumference (MUAC) and skinfolds thicknesses (triceps, subscapular, abdominal and the sum of skinfolds). Blood Pb level was evaluated and divided into two groups: above (>3.7 µg/dL) and below median value (≤3.7 µg/dL). RESULTS: Analysis of covariance (with children's age controlled as a covariate) revealed that children with blood Pb level above median value had significantly lower values of BMI, MUAC and all skinfolds (at least p < 0.01). However, this effect was significant only in boys, whereas in girls differences were non-significant (p > 0.05). The highest effect size of blood Pb level was noted for skinfolds thicknesses (partial η2: 0.015 for the sum of skinfolds). CONCLUSIONS: Nutritional status in children with higher blood Pb level is significantly impaired in preadolescent boys, who appear to be more sensitive to this environmental factor. Our findings indicate a particular need for nutritional and environmental interventions among preadolescent children in regions with higher lead exposure.

Short-term exposure to ambient air pollution and hospital visits for IgE-mediated allergy: A time-stratified case-crossover study in southern China from 2012 to 2019.

BACKGROUND: Because of the limited epidemiological evidence on the association between acute air pollutants and allergy, there is a need to investigate this association, especially between the short-term exposure to air pollution and the serum Immunoglobulin E (IgE)-mediated allergy. METHODS: A total of 39,569 IgE test results and demographic characteristics were obtained in the First Affiliated Hospital of Guangzhou Medical University between August 2012 and September 2019. Ninety-nine specific allergens were tested according to clinical diagnosis. The logistic regression was used to assess the effects of CO, NO2 and PM2.5 exposure on the risk of sensitization to specific inhalant/food allergens. Generalized additive models with multivariate adjustments were utilized to model the exposure-response relationship. Stratified analyses were performed to estimate the reliability of correlations in various subgroups. FINDINGS: Single-pollutant models indicate that the 3-day moving average (lag2-4) of CO, PM2.5 or NO2 is associated with the increased risk for allergic diseases related to specific inhaled allergens. In multi-pollutant models, the adjusted Odds Ratio (OR) 95% (Confidence Interval, CI) increases by 8% (95% CI, 2%-15%) for per increment of 0.2 mg/m3 in CO levels, and rises by 8% (95% CI, 2%-13%) for each increase of 16.3 µg/m3 in PM2.5 concentration. The associations are stronger in youngsters (<18, years) but not significantly different by gender. Particularly, a significantly stronger association between PM2.5 exposure and hospital visits for inhaled allergy is observed in patients who are exposed to lower concentration of SO2 (<10.333 µg/m3) and higher levels of NO2 (≥42.0 µg/m3), as well as patients enrolled after 2017. INTERPRETATION: The short-term exposure to CO/PM2.5 increases the number of hospital visits for IgE-mediated allergy, especially for the sensitization to specific inhalant allergens. Therefore, to prevent inhaled allergies, the public policy for controlling air pollution needs to be considered seriously. FUNDING: This study was supported by the University of Macau (grant numbers: FHS-CRDA-029-002-2017 and MYRG2018-00,071-FHS) as well as the Science and Technology Development Fund, Macau SAR (File no. 0004/2019/AFJ and 0011/2019/AKP). This work was also supported by the National Natural Science Foundation of China (81,871,736), the National Key Technology R&D Program (2018YFC1311902), the Guangdong Science and Technology Foundation (2019B030316028), the Guangzhou Municipal Health Foundation (20191A011073), and the Guangzhou Science and Technology Foundation (201,804,020,043).

Cellulose-derived polyols as high-capacity adsorbents for rapid boron and organic pollutants removal from water.

Excess boron in water could result in a critical hazard to plants and humans. Traditional treatment approaches cannot efficiently remove boron from water, especially during seawater desalination using reverse osmosis technology. Achieving satisfactory adsorption capacity and rate for boron remains an unmet goal for decades. Herein, we report cellulose-derived polyols as high-performance adsorbents that can rapidly remove boron and organic pollutants from water. Cellulose-derived polyols were synthesized from saccharides and cellulose via controlled radical polymerization and click reaction. Remarkably, CA@NMDG can adsorb boron with an astonishing capacity of ~34 mg g-1 in 10 min, which surpasses all those cellulose-based materials reported thus far, meanwhile, much faster than those of commercial adsorption resin. Moreover, cellulose-derived polyols also showed high removal efficiencies (70-98% in several minutes) toward certain organic pollutants, including Congo red and Reactive Blue 19. The water-insoluble characteristic of cellulose-derived polyols is advantageous to be separated from the treated sewage after adsorption for reuse. This work provides a novel insight into the fabrication of safe, fast, and high-capacity cellulose adsorbents for water purification.

Harmful Algal Blooms in Aquaculture Systems in Ngerengere Catchment, Morogoro, Tanzania: Stakeholder's Experiences and Perception.

The aquaculture sector has experienced fast growth as a result of livelihood diversification initiatives among small-scale farmers in Tanzania. Regrettably, the dynamics of harmful algal blooms (HABs) have been overlooked despite the noticeable forcing of climate variability, the interaction between social-economic activities, and domestic water supply reservoirs. This study aimed at surveying the occurrence, experiences, and perceptions of HABs in aquaculture systems from stakeholders in the Ngerengere catchment, Morogoro, Tanzania. A cross-sectional survey focus group discussion (FDG), key informant interviews, and anecdotal observation were adopted. A convenient and purposive sample population was drawn from pond owners, registered water users, and government officials in the catchment. For data analysis, descriptive statistics and constant comparison were performed. Most respondents (95%) were able to recognize the image of blooms displayed. Approximately 70% of the respondents agreed that water quality has deteriorated over time, and blooms occur during the dry season. Further, 60% of the respondents agreed that water pollution is a serious problem attributed to sources other than industrial discharge. There was no consensus regarding the health impacts associated with HABs. Raising awareness on HABs is of paramount importance as it will provide the basis for the development of HABs management framework and health risk assessment.

Modelling and evaluation of combustion emission characteristics of COME biodiesel using RSM and ANN-a lead for pollution reduction.

Nowadays, the emissions from the diesel engines are focused lot to minimise the environmental pollutions in accordance with the emission standards. In this regard, biodiesels are found to be efficient for the diesel engines due to their higher energy contents and low exhaust emissions. Use of biofuel in association with diesel will be an efficient way for the cost-effective performance of the diesel engines with reduced pollutions. The COME is an efficient combustible oil, in which the diesel is blended at different proportions to identify their suitability in the diesel engines. In this regard, the properties of the COME-Diesel blends are determined and analysed for their influence on the combustion characteristics. To understand the performance and emission characteristics of blends, experiments are carried out on the variable compression ratio (VCR) engine keeping the blend, compression ratio, load, and speed as variables. The response surface methodology (RSM) used as a tool for designing and conducting the experiments according to the predetermined variables. The experimental sets generated are performed to determine the NO and HC emissions (response functions). The adequacy of the models is verified through ANOVA and through the p and F tests. The experimental design matrix is also used in training the artificial neural network (ANN) to develop the empirical models. The models from RSM and ANN are experimented and the results obtained from both the models are compared for their accuracy levels. Once the hypothesis is developed for the biodiesel and engine setup, the emission models will be used for the optimising the engine operating parameters and blends to minimise the pollutions from engine for wide operating conditions.

The Association Between Ambient Air Pollution and Atrial Fibrillation.

Atrial fibrillation (AF) is the most common cardiac arrhythmia; it has been known to increase the risk of stroke and heart failure. The association between air pollutants and AF has remained to be controversial. Thus, in this study, we sought to undertake a systematic review and meta-analysis in order to assess the short- and long-term effects of ambient air pollution on AF.We searched PubMed, Web of Science, Embase, and Ovid for all related studies up to October 2019. We used the random-effects model to estimate the excess risk percentage (ER%) and confidence intervals (CI) for particulate matter with diameter ≤ 2.5 (PM2.5) and ≤ 10 µm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O3), and carbon monoxide (CO). Results were further analyzed by subgroups according to location, age, outcome, and gender.In total, 18 studies were included in our meta-analysis: 5 evaluated for long-term effects, 12 for short-term effects, and 1 for both long- and short-term effects. For the short term, ER per 10 µg/m3 increase of pollutants was 1.8% (0%-3.7%) for PM2.5 and 1.1% (-0.2%-2.4%) for PM10; per 10 parts per billion (ppb) increment of gaseous pollutions was 3.2% (0.6%-5.8%) for NO2, 2.9% (0.3%-5.7%) for SO2, 0.5% (-3.4%-4.7%) for O3, and 2.0% (-1.3%-5.4%) for CO per 1000 ppb change. The subgroup analysis showed the short-term effect was significantly different by region, gender, outcome, and age. Meanwhile, in the long term, except for O3, a statistically significant association was noted between AF incidence and all pollutants.Our meta-analysis suggests that short-term exposure to part of pollutants (PM2.5, SO2, and NO2) increases AF attack. Further, long-term exposure to air pollution can significantly contribute to the incidence of AF in a healthy population.

Bibliometrics and visualization analysis regarding research on the development of microplastics.

Microplastics have caused considerable harm to the environment and threatened human health due to their strong adsorption and hard biodegradation. Therefore, the research of microplastic received increasing attention recently, producing numbers of related achievements. To comprehensively grasp the quantitative information of published papers on "microplastics," we analyzed the research progress and hotspots of "microplastics" through visualization software "VOSviewer." The results show that the number of literature on microplastics published from 2009 to 2019 increased exponentially (R2 = 0.9873). The top 10 cited references are mainly in "zooplankton ingesting microplastics," "microplastics in artificially cultivated bivalve," "microplastics in surface waters such as lakes," etc. The cutting-edge microplastics research is adsorption, biodegradation, ingestion and accumulation model, and toxicity analysis. In addition, the results predict that the combination of constructed wetland, biotechnology, and photocatalysis to remove microplastics will become new hotspots. The study provides researchers in microplastics with an overview of existing research and directional guidance for future research.

An innovative strategy for synchronous treatment of combined heavy metal and organic pollutants through polysaccharide gel encapsulating S2.

In many industrial fields, treatment of composite contaminations involving inorganic heavy metal ions and organic pollutants simultaneously remains a tremendous challenge. In this paper, an innovative strategy based on the gelation process of Sodium Alginate (SA) was proposed for synchronous treatment of composite pollutants. Through a pre-gelation step, SA gel balls encapsulated with S2- (SA/S2- gel) were formed and immersed into polluted solutions containing Pb2+/Cd2+ and Cd2+/dye. The removal efficiency of Pb2+/Cd2+ by SA/S2- gel were both increased compared with pure SA gel. The adsorbed Pb2+/Cd2+ was in-situ transformed into PbS/CdS quantum dots (QDs) possessing photo-catalytic activity, which induced the degradation of dyes under UV irradiation. In this respect, the proposed SA/S2- system might provide a high-performance and energy-saving way for comprehensive treatment of inorganic heavy metal and organic industrial pollutants.

Alternative Evaluation to Earthworm Toxicity Test in Polychlorinated Biphenyls Spiked and Remediated Soils.

Polychlorinated biphenyls (PCBs) are a class of persistent organic pollutants that pose a threat to environment and human health. Aiming at predicting PCBs risk in actual soil ecosystem, this study was conducted by chemical and biological methods to assess the bioavailability of PCBs in spiked soil, and in field-contaminated soils before or after remediation. The three chemical methods were Soxhlet, n-butanol and hydroxypropyl-ß-cyclodextrin (HPCD). Results were compared to actual PCB bioaccumulation in earthworms (Eisenia fetida). HPCD extraction was the best to predict the actual PCB bioaccumulation in all soils. The results suggest that HPCD could be an effective alternative method to earthworm toxicity test. This study provides strategy to understand the toxicity assessment in contaminated soil and soil after remediation.