A Novel Reactivity of Phosphanylalumane (>P-Al<): Reversible Addition of a Saturated Interelement Bond to Olefins.

The reversible addition of olefins to a phosphanylalumane, P-Al single-bond species, was investigated. The P-Al bond added to ethylene and relatively small terminal alkenes (propylene and hex-1-ene) at room temperature to give the corresponding alkene adducts. Heating the terminal alkene adducts released the corresponding alkenes and regenerated the P-Al bond, but no release of ethylene was observed even under vacuum conditions. The reactivity of ethylene adduct as a new saturated C2 vicinal P/Al-based FLP was also investigated. The ethylene adduct was found to undergo complexation with nitriles to give the corresponding nitrile adducts to the Al center, which retained the ethylene tether as in the case of the corresponding P/B-based FLP. However, the reactivity of ethylene toward CO2 and benzaldehyde differed from that of the P/B system giving the corresponding adducts.

Sonochemical synthesis of novel thermo-responsive polymer and tungsten dioxide composite for the temperature-controlled reversible "on-off" electrochemical detection of ß-Blocker metoprolol.

Thermo-responsive polymer nanocomposite based on poly (styrene-co-N-isopropylacrylamide) hybrid tungsten dioxide (WO2@PS-co-PNIPAM) was synthesized by a facile ultrasonic irradiation (Frequency; 20 kHz, power; 180 W, calorimetrically determined power; 5.73 W in the bath, and Type; probe) method in the presence of water as inisolv. The as-synthesized WO2@PS-co-PNIPAM modified glassy carbon electrode (WO2@PS-co-PNIPAM/GCE) was acting as a reversibly switched detection for the electrooxidation of metoprolol (MTP), with the thermal stimuli response of the PNIPAM. In below lower critical solution temperature (LCST), the PS-co-PNIPAM expanded to embed the electroactive sites of WO2, and the MTP could not proceed via the polymer to attain electronic transfer, indicating the "off" state. Rather, in above LCST, the PS-co-PNIPAM shrank to reveal electroactive sites and expand cyclic voltammetric background peak currents, the MTP was capable to undergo electro-oxidation reaction usually and produce the response current, indicating "on" state. Additionally, the proposed sensor had excellent sensitivity (2.21 µA µM-1 cm-2), wide dynamic range (0.05-306 µM), and a low limit of detection of 0.03 µM for MTP. Intriguingly, the fabricated sensor demonstrates the good selectivity towards the detection of MTP among the possible interfering compounds. Eventually, the WO2@PS-co-PNIPAM/GCE has been utilized in the analysis of MTP in human blood serum samples.