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Forensic Sci Int Genet ; 9: 134-41, 2014 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24528591

RESUMO

Often in forensic cases, the profile of at least one of the contributors to a DNA evidence sample is unknown and a database search is needed to discover possible perpetrators. In this article we consider two types of search strategies to extract suspects from a database using methods based on probability arguments. The performance of the proposed match scores is demonstrated by carrying out a study of each match score relative to the level of allele drop-out in the crime sample, simulating low-template DNA. The efficiency was measured by random man simulation and we compared the performance using the SGM Plus kit and the ESX 17 kit for the Norwegian population, demonstrating that the latter has greatly enhanced power to discover perpetrators of crime in large national DNA databases. The code for the database extraction strategies will be prepared for release in the R-package forensim.


Assuntos
Impressões Digitais de DNA , DNA/análise , Bases de Dados de Ácidos Nucleicos , Armazenamento e Recuperação da Informação/métodos , Modelos Genéticos , Frequência do Gene , Genótipo , Humanos , Funções Verossimilhança , Repetições de Microssatélites
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