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1.
Membranes (Basel) ; 13(12)2023 Dec 12.
Artigo em Inglês | MEDLINE | ID: mdl-38132909

RESUMO

The main objective of this study is the evaluation of the use of a synthetic membrane, Nuclepore, as a model for permeation studies through sublingual mucosa. The permeability of two types of membranes, porcine sublingual oral mucosa and a synthetic Nuclepore membrane, to water was compared. Moreover, the water permeability of membranes modified with waterproofing formulations was measured to study their ability to protect against the penetration of viruses, toxins, etc. A relatively high correlation (R2 0.88) was obtained between the transmucosal water loss (TMWL) values of the artificial membrane and the mucosa. These results support the possible use of this synthetic membrane in the screening of the water permeability of formulations. In addition, studies of the permeation of different actives, drugs, and biocides through the two membranes were carried out, and these results were compared with their skin permeation data. The synthetic membrane does not seem to discern between compounds in terms of permeability. However, the permeation of caffeine through intact or modified membranes incorporating waterproofing formulations presents similar permeation profiles through the synthetic membrane and mucosa. The results from these assays should lend support to the use of this synthetic membrane when screening formulations to be applied in oral penetration studies.

2.
Materials (Basel) ; 16(22)2023 Nov 12.
Artigo em Inglês | MEDLINE | ID: mdl-38005065

RESUMO

The article analyses the impact of wind suction on roof coverings glued with polyurethane adhesives to flat roofs, i.e., roofs with an up to 20% slope. The impact of the cyclical wind was simulated in fatigue tests, gradually increasing the test pressure in repeated sequences until the first delamination occurred. The tests were carried out for eight test sets, with concrete and trapezoidal sheets used as a construction substrate, on whose surface thermal insulation layers were glued with polyurethane adhesive; the thermal insulation layers were EPS (expanded polystyrene) and PIR (polymer mainly of polyisocyanurate groups), respectively, followed by flexible sheets, i.e., a laminated PVC membrane (polyvinylchloride) and an EPDM (terpolymer of ethylene, propylene and a diene with a residual unsaturated portion of diene in the side chain)-type rubber-based membrane. The test results were compared with the functional requirements determined with computational simulation methods for the maximum wind load values on the example of wind loads for Poland. The tests confirmed that some polyurethane adhesives could ensure the operation of flexible sheets used as flat roof coverings that are failure-free from the point of view of resistance to wind suction.

3.
ACS Appl Mater Interfaces ; 15(48): 56537-56546, 2023 Dec 06.
Artigo em Inglês | MEDLINE | ID: mdl-37992157

RESUMO

Antifouling is essential to guaranteeing the sensitivity and precision of flexible sensing interfaces. Materials and structures are the two primary strategies. However, optimizing the inherent microstructures to integrate waterproofing and sensing is rarely reported. To improve the liquid repellency of micropyramid structures, this work presents a study of the design and fabrication of T-shaped micropyramid structures. These structures are patterned uniformly and largely on polydimethylsiloxane (PDMS) skin by the new process of two-step magnetic induction. The waterproofing is related to the breakthrough pressure and the liquid repellency, both of which are a function of structural characteristics, D, and material properties, θY. At the breakthrough transition, two failure models distinguished by θY appear: the depinning transition and the sagging transition. Meanwhile, when considering D in practice, some models will shift and occur early. The D value regulates the transition of the material's wettability to the liquid repellency. The influence of the material's inherent nonwettability on liquid repellency diminishes as D decreases, and the transition from completely wetting liquids to super-repellents can be achieved. Experiments demonstrate that for D = 0.3 under water the resistance is approximately 142 times larger than the depth of the structure, considerably facilitating the waterproofing of conventional micropyramid arrays. This work provides a novel method for fabricating flexible T-shaped micropyramid array structures and opens a new window on flexible sensing interfaces with excellent waterproofing.

4.
J Indian Assoc Pediatr Surg ; 28(5): 375-386, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37842208

RESUMO

Introduction: Despite the advancements in technique and technology, urethrocutaneous fistula (UCF) formation continues to be the most common complication after hypospadias repair. Objective: The objective of the current synthesis is to define the indications of PATIO technique for UCF repair. Materials and Methods: The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Scopus, Ovid, Embase, Web of Science, and Google Scholar were interrogated for studies presenting primary data upon UCF repair by the PATIO technique. Data analysis was performed on MedCalc and R software. Results: Eighteen studies were identified relevant to the current context: inversion of UCF tract has been described in 13 and ligation in 5. There were 2 duplications (abstract and manuscript). The overall success for PATIO is 88.2% (314/356). The success rate was variable between classic PATIO (inversion at 87.2%), ligation-inversion at 86.9%, and ligation alone at 88.9%. The success rate was not improvised upon by supplementing inversion of UCF tract with ligation (p = 0.957) or addition of a waterproofing layer (p = 0.622). PATIO has been used for single or multiple UCFs post hypospadias repair, genital piercing, and genitoplasty in cis- or transgender population for UCF up to 5 mm in size. The success rates were best for UCF <2 mm and worst for those approaching 5 mm. The results were, however, unaffected by the location of UCF along the penile shaft. Besides, the use of urethral catheter is optional and may be eliminated with shorter hospitalization. Conclusions: PATIO repair may be considered for repair of UCFs (a) with diverse etiologies, (b) located anywhere along the penile shaft included coronal UCF, (c) preferably <4 mm in size, (d) single or multiple in number; multiple PATIOs may be done in the same setting, (e) in patients unwilling for prolonged hospitalization, (f) in patients unwilling for a urethral catheter, and (g) in hypospadias cripples wherein mobilization of distant tissues such as tunica vaginalis flap or a buccal mucosal graft may be required for supplementing the UCF repair.

5.
J Exp Biol ; 226(16)2023 08 15.
Artigo em Inglês | MEDLINE | ID: mdl-37497773

RESUMO

An insect's cuticle is typically covered in a layer of wax prominently featuring various hydrocarbons involved in desiccation resistance and chemical communication. In Argentine ants (Linepithema humile), cuticular hydrocarbons (CHCs) communicate colony identity, but also provide waterproofing necessary to survive dry conditions. Theory suggests different CHC compound classes have functional trade-offs, such that selection for compounds used in communication would compromise waterproofing, and vice versa. We sampled sites of invasive L. humile populations from across California to test whether CHC differences between them can explain differences in their desiccation survival. We hypothesized that CHCs whose abundance was correlated with environmental factors would determine survival during desiccation, but our regression analysis did not support this hypothesis. Interestingly, we found the abundance of most CHCs had a negative correlation with survival, regardless of compound class. We suggest that the CHC differences between L. humile nests in California are insufficient to explain their differential survival against desiccation, and that body mass is a better predictor of desiccation survival at this scale of comparison.


Assuntos
Formigas , Animais , Formigas/química , Dessecação , Hidrocarbonetos/química , Tamanho Corporal
6.
J Clin Med ; 12(6)2023 Mar 21.
Artigo em Inglês | MEDLINE | ID: mdl-36983404

RESUMO

Waterproofing spray-associated lung injury (WALI) is an acute respiratory disorder characterized by bilateral diffuse lung injury on chest computed tomography (CT). In most cases, the symptoms and abnormal radiographic findings of WALI patients improve spontaneously over several days; however, some cases have persistent symptoms and abnormal shadows for >1 week. The distinctive features of each WALI are unknown. Herein, we present two new cases of WALI that we encountered in our hospital, and we previously reported two other cases of WALI. We examined the characteristics of WALI in our cases and 39 other cases of WALI definitively diagnosed and reported in PubMed and the Japan medical board with verifiable data during a 15-year period. We compared the clinical characteristics of the 22 cases in which the patients' symptoms were resolved within 1 week (early improvement) to those of the 21 cases in which the symptoms were resolved after >1 week (delayed improvement). The WALI cases with delayed improvement had significantly more shadowing that extended over the entire lung field and was not biased in intensity toward the upper or lower lung field. In addition, the serum white blood cell (WBC) counts and serum Krebs von den Lungen-6 (KL-6) levels differed significantly between the cases of early and delayed improvement of WALI.

7.
Polymers (Basel) ; 15(4)2023 Feb 17.
Artigo em Inglês | MEDLINE | ID: mdl-36850296

RESUMO

Building structures are prone to cracking, leakage, and corrosion under complex loads and harsh marine environments, which seriously affect their durability performance. To design cementitious composites with excellent mechanical and impermeability properties, Engineered Cementitious Composites (ECCs) doped with ultrahigh molecular weight polyethylene short-cut fibers (PE-ECCs) were used as the reference group. Different types (XYPEX-type from Canada, SY1000-type from China) and doses (0%, 0.5%, 1.0%, 1.5%, 2.0%) of Cementitious Capillary Crystalline Waterproofing materials (CCCWs) were incorporated. The effect of CCCWs on the mechanical and impermeability properties of PE-ECCs, and the microscopic changes, were investigated to determine the best type of CCCW to use and the best amount of doping. The results showed that with increasing the CCCW dosage, the effects of both CCCWs on the mechanical and impermeability properties of PE-ECC increased and then decreased, and that the best mechanical and impermeability properties of PE-ECC were achieved when the CCCW dosing was 1.0%. The mechanical properties of the PE-ECC were more obviously improved by XYPEX-type CCCW, with a compressive strength of 53.8 MPa, flexural strength of 11.8 MPa, an ultimate tensile stress of 5.56 MPa, and an ultimate tensile strain of 7.53 MPa, which were 37.95%, 53.25%, 14.17%, and 21.65% higher than those of the reference group, respectively. The effects of the two CCCWs on impermeability were comparable. CCCW-PE-ECC(X1.0%) and CCCW-PE-ECC(S1.0%) showed the smallest permeation heights, 2.6 mm and 2.8 mm, respectively. The chloride ion diffusion coefficients of CCCW-PE-ECC(X1.0%) and CCCW-PE-ECC(S1.0%) exhibited the smallest values, 0.15 × 10-12 m2/s and 0.10 × 10-12 m2/s, respectively. Micromorphological tests showed that the particle size of the XYPEX-type CCCW was finer, and the intensity of the diffraction peaks of C-S-H and CaCO3 of PE-ECC increased after doping with two suitable doping amounts of CCCW. The pore structure was improved, the surface of the matrix was smoother, and the degree of erosion of hydration products on the fiber surface was reduced after chloride ion penetration. XYPEX-type CCCW demonstrated a more obvious improvement in the PE-ECC pore structure.

8.
Materials (Basel) ; 15(22)2022 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-36431742

RESUMO

Current trends towards saving energy and designing sustainable buildings result in most designers focusing on achieving the best thermal parameters, thereby neglecting a careful moisture analysis. Excessive moisture content in building partitions degrades the mechanical properties of materials, reduces thermal insulation properties (which leads to an increase in the demand for thermal energy) and worsens the microclimate in rooms. Modern digital solutions help create appropriate models of partitions that work for many years in good environmental conditions. According to the analysis of air parameters, 1 m3 of air at 20 °C contains approx. 17.3 g of water. When the temperature of the air reaches the dew point temperature, water vapour condenses. The dew point depends on air temperature and relative air humidity; for instance, at the same air temperature of 20 °C, the dew point temperature at 40% relative air humidity is 6 °C, whereas at 90% relative humidity, it is over 18 °C. This means that the higher the value of relative humidity in the room at a certain temperature, the lower the temperature that will cause condensation. The article presents a numerical analysis of the insulation work of flexible materials within the layers of ventilated partitions in an 8-year simulated period of varying environmental conditions. The aim of the article is to analyze different models and variants of ventilated partition operation with respect to the advisability of using a vapour barrier to avoid the problem of destruction of thermal insulation and finishing layers of a ventilated roof.

9.
Materials (Basel) ; 15(19)2022 Oct 02.
Artigo em Inglês | MEDLINE | ID: mdl-36234195

RESUMO

This study seeks to analyze how the degree of carbonation and the application of waterproofing and anticorrosive materials affect carbonation in water reservoirs among the water treatment facilities managed by the Seoul Metropolitan Government. To guarantee similarity of the experimental group, 42 highly similar water reservoirs were selected from among the water supply reservoirs currently in operation in Seoul. On-site carbonation assessments were performed in order to derive the carbonation rate coefficients. In the water reservoirs with applied waterproofing and anticorrosive materials immediately after public service, the upper and lower limits were D = 1.13t and D = 0.29t, respectively, whereas those of the water reservoir applied with waterproofing and anticorrosive materials after 15 years of service life were D = 1.89t and D = 0.94t, respectively. The comparative analysis showed that the rate of reduction in the carbonation rate was about 10.4% to 16.8% in the water reservoirs applied with waterproofing and anticorrosive methods after 15 years of service life. However, reduction in the carbonation rate was about 46.4% to 74.3% in the water reservoirs applied with waterproofing and anticorrosive methods at the initial stage of service life. It was confirmed that the early application of waterproofing and anticorrosive materials is effective in suppressing carbonation of concrete water reservoir structures.

10.
ACS Appl Mater Interfaces ; 14(38): 43656-43665, 2022 Sep 28.
Artigo em Inglês | MEDLINE | ID: mdl-36112473

RESUMO

Sand is one of the most fundamental construction materials that is of significant importance and widely used for making concrete, plasters, and mortars, and also for filling under floor and basements. Sand-derived functional materials, for instance superhydrophobic sand, which can be used to prepare liquid marble, separate oil-water mixtures, and transport liquids, have recently been a highly topical and promising research field. However, such materials are mainly prepared using valuable surface modification agents via complicated procedures that are difficult for mass-production, which restricted their true applications. Here, we developed a simple, low-cost, and efficient method for the development of sand-based hierarchical micro/nanostructured composite materials with diverse applications. Briefly, micro/nanostructured superhydrophobic sand was synthesized by one-step in situ growth of a network layer of silicone nanofilaments on the surface of sand microparticles, using only one cheap chemical of small molecules of silanes. The as-prepared superhydrophobic sand displays excellent performance in waterproofing, water storage, soil moisturizing, and oil-water separation. Furthermore, sand-supported micro/nanocomposite catalysts were obtained through covalent attachment of polyamines on the surface of silicone nanofilaments. Such composites, packed in a glass column, were used as a simple flow reactor for Knoevenagel condensation reactions. Quantitative amounts of pure products without further purification can be obtained in such a simple way that just allowing the reactants solution flows through the composite catalysts driven by gravity. These results pave the way toward the development of sand-based multifunctional materials with great potential for industrial use, given their versatile functions and excellent performances but easy-to-fabricate, low-cost preparation procedure.

11.
J Exp Biol ; 225(15)2022 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-35848820

RESUMO

The often complex cocktails of hydrocarbon compounds found on the cuticles of insects can serve both naturally and sexually selected functions, contributing to an individual's ability to withstand water loss and attract mating partners. However, whether natural and sexual selection act synergistically or antagonistically on a species' cuticular hydrocarbon (CHC) profile remains unclear. Here, we examined the ontogeny of the CHC profile in a species of cricket, Teleogryllus oceanicus, while manipulating humidity during development. We predicted that juvenile crickets should produce only those compounds that contribute to desiccation resistance, while those compounds contributing specifically to male attractiveness should be produced only at sexual maturity. Further, if attractive CHCs come at a cost to desiccation resistance as predicted by some models of sexual selection, then males reared under low humidity should be constrained to invest less in attractive CHCs. Crickets reared under low humidity produced more long-chain methyl-branched alkanes, alkenes and alkadienes than did crickets reared under high humidity. The abundance of n-alkanes was unaffected by humidity treatment. Sexual dimorphism in the CHC profile was not apparent until adult emergence and became exaggerated 10 days after emergence, when crickets were sexually mature. Males produced more of the same compounds that were increased in both sexes under low humidity, but the humidity treatment did not interact with sex in determining CHC abundance. The data suggest that CHC profiles which protect crickets from desiccation might have synergistic effects on male attractiveness, as there was no evidence to suggest males trade-off a CHC profile produced in response to low humidity for one associated with sexual signalling.


Assuntos
Preferência de Acasalamento Animal , Alcanos , Animais , Feminino , Hidrocarbonetos , Masculino , Caracteres Sexuais , Seleção Sexual
12.
Insect Mol Biol ; 31(6): 772-781, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-35860987

RESUMO

The oriental fruit fly Bactrocera dorsalis (Hendel) is expanding its distribution to higher latitudes. Our goal in this study was to understand how B. dorsalis adapts to higher latitude environments that are more arid than tropical regions. Cuticular hydrocarbons (CHCs) on the surface of the epicuticle in insects act as a hydrophobic barrier against water loss. The essential decarbonylation reaction in CHC synthesis is catalysed by CYP4G, a cytochrome P450 subfamily protein. Hence, in B. dorsalis it is necessary to clarify the function of the CYP4G gene and its role in desiccation resistance. CYP4G100 was identified in the B. dorsalis genome. The complete open reading frame (ORF) encodes a CYP4 family protein (552 amino acid residues) that has the CYP4G-specific insertion. This CYP4G gene was highly expressed in adults, especially in the oenocyte-rich peripheral fat body. The gene can be induced by desiccation treatment, suggesting its role in CHC synthesis and waterproofing. Silencing of CYP4G100 resulted in a decrease of CHC levels and the accumulation of triglycerides. It also increased water loss and resulted in higher desiccation susceptibility. CYP4G100 is involved in hydrocarbon synthesis and contributes to cuticle waterproofing to help B. dorsalis resist desiccation in arid environments.


Assuntos
Proteínas de Insetos , Tephritidae , Animais , Proteínas de Insetos/metabolismo , Dessecação , Tephritidae/genética , Sistema Enzimático do Citocromo P-450/metabolismo , Hidrocarbonetos/metabolismo , Drosophila/genética , Água
13.
Polymers (Basel) ; 14(11)2022 May 30.
Artigo em Inglês | MEDLINE | ID: mdl-35683894

RESUMO

In this work, innovative graphene oxide-doped waterproofing bituminous membranes, also called roof bituminous membranes, were prepared and characterized in terms of physicochemical and vapor transport properties. The results showed that the introduction of a small amount of GO increased the mechanical resistance of the doped membranes compared to the native one. Moreover, the addition of the GO leads to a remarkable chemical stability of the membranes when exposed to UV radiation and high temperatures. Furthermore, a decrease in water vapor permeation was observed when GO was present in the membrane matrix compared to native bituminous membranes, demonstrating that an addition of GO can boost the waterproofing properties of these bituminous membranes.

14.
Front Public Health ; 10: 830429, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35284363

RESUMO

Background: Acute respiratory distress syndrome (ARDS) is a serious respiratory disease, caused by severe infection, trauma, shock, inhalation of harmful gases and poisons and presented with acute-onset and high mortality. Timely and accurate identification will be helpful to the treatment and prognosis of ARDS cases. Herein, we report a case of ARDS caused by occupational exposure to waterproofing spray. To our knowledge, inhalation of waterproofing spray is an uncommon cause of ARDS, and what makes our case special is that we ruled out concurrent infections with some pathogens by using metagenomic next-generation sequencing (mNGS) as an auxiliary diagnosis, which presents the most comprehensive etiological examination of similar reports. Case Presentation: A previously healthy 25 years old delivery man developed hyperpyrexia, chest tightness, cough and expectoration. The symptoms occurred and gradually exacerbated after exposure to a waterproofing spray. The chest computed tomography (CT) finding showed diffuse ground glass and infiltrative shadows in both lungs. The diagnosis of ARDS related to waterproofing spray was established on the basis of comprehensive differential diagnosis and etiological examination. The patient achieved good curative effect after proper systemic glucocorticoid therapy. Conclusions: The diagnosis and differential diagnosis of acute respiratory failure for outdoor workers, such as delivery drivers or hikers, should be considered whether toxic aerosol exposure exists from daily contacts. The case can educate the public that more attention should be paid to avoid exposure to these chemicals by aerosols/ingestion mode and some preventive strategies should be taken in occupational environment. The treatment effect of glucocorticoids is significant in ARDS patients with general chemical damage caused by inhaling toxic gases and substances.


Assuntos
Exposição Ocupacional , Síndrome do Desconforto Respiratório , Adulto , Aerossóis/toxicidade , Gases , Humanos , Exposição por Inalação , Masculino , Exposição Ocupacional/efeitos adversos , Síndrome do Desconforto Respiratório/induzido quimicamente
15.
Artigo em Inglês | MEDLINE | ID: mdl-35328848

RESUMO

The Metropolitan Area of Guadalajara (MAG) experiences water shortage and overexploitation of aquifers. In addition, it suffers from seasonal flooding that is channeled towards inadequate sanitary drainage, creating a strong negative environmental impact. These problems are rooted in the waterproofing of the urban surface. Many cities around the world have used deep injection wells to recover aquifers and remove surface waters. Certain geohydrological conditions are required for the implementation of these deep injection wells, deeper than 30 m, such as significant surface runoff, acceptable water quality for infiltration, considerable depth in the phreatic levels, and good subsoil permeability. All of these conditions exist in the MAG or could be achieved without significant investment. An assessment is presented exploring the viability for a solution based on this technology, as a strategy to recover aquifers and reduce flooding. The first step was to identify, through map algebra, a micro-basin suitable for this technology. Then, mean runoff volumes were obtained and a stratigraphic profile was carried out based on 19 standard penetration tests (SPT). With these data, a numerical simulation of deep injection wells of different dimensions was performed, providing recommendations for a solution based on these calculations. The results show that both problems can be solved with this relatively simple and cheap technology supporting public health.


Assuntos
Água Subterrânea , Cidades , Inundações , Qualidade da Água
16.
Adv Healthc Mater ; 11(12): e2102703, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35285162

RESUMO

On-skin healthcare patch-type devices have great technological challenges in monitoring full-day activities and wearing for multiple days without detachment. These challenges can be overcome when the sensor is air permeable but waterproof. This study presents a light-weight, highly stable, and stretchable Au electrode that is fabricated by sputtering on an imidized nanofiber mat. The contact surface of the electrode is hydro-wetting and the outer surface of the electrode is hydrophobic, so the porous electrode simultaneously has excellent sweat permeability and waterproofing capabilities. The electrode is applied to the electrocardiogram sensor for monitoring the cardiac signals for five consecutive days without detaching while doing various full-day activities such as relaxing, exercising, showering, and sleeping. This study suggests a modular setup of the electrodes and the cardiac signal processing unit for activating the device when cardiac monitoring is required.


Assuntos
Dispositivos Eletrônicos Vestíveis , Eletrocardiografia , Eletrodos , Monitorização Fisiológica , Suor
17.
Adv Mater ; 34(17): e2107938, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34969155

RESUMO

Electrospinning is a significant micro/nanofiber processing technology and has been rapidly developing in the past 2 decades. It has several applications, including advanced sensing, intelligent manufacturing, and high-efficiency catalysis. Here, multifunctional protective membranes fabricated via electrospinning in terms of novel material design, construction of novel structures, and various protection requirements in different environments are reviewed. To achieve excellent comprehensive properties, such as, high water vapor transmission, high hydrostatic pressure, optimal mechanical property, and air permeability, combinations of novel materials containing nondegradable/degradable materials and functional structures inspired by nature have been investigated for decades. Currently, research is mainly focused on conventional protective membranes with multifunctional properties, such as, anti-UV, antibacterial, and electromagnetic-shielding functions. However, important aspects, such as, the properties of electrospun monofilaments, development of "green electrospinning solutions" with high solid content, and approaches for enhancing adhesion between hydrophilic and hydrophobic layers are not considered. Based on this systematic review, the development of electrospinning for protective membranes is discussed, the existing gaps in research are discussed, and solutions for the development of technology are proposed. This review will assist in promoting the diversified development of protective membranes and is of great significance for fabricating advanced materials for intelligent protection.


Assuntos
Nanofibras , Antibacterianos , Interações Hidrofóbicas e Hidrofílicas , Membranas Artificiais , Nanofibras/química
18.
Intern Med ; 61(12): 1881-1886, 2022 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-34776487

RESUMO

An 82-year-old Japanese man with idiopathic pulmonary fibrosis (IPF) experienced dyspnea after using a waterproofing spray in a closed room. He presented with hypoxemia and his chest computed tomography showed additive bilateral diffuse ground-glass attenuation on fibrosis, which was diagnostic of an acute exacerbation of IPF (AE-IPF). Combined treatment with high-dose corticosteroids and immunosuppressants were ineffective, and he later died of respiratory failure. Autopsy findings showed diffuse alveolar damage with honeycombing. His medical history and autopsy histopathology suggested AE-IPF caused by the inhalation of a waterproofing spray.


Assuntos
Fibrose Pulmonar Idiopática , Pneumopatias , Idoso de 80 Anos ou mais , Autopsia , Dispneia , Humanos , Fibrose Pulmonar Idiopática/tratamento farmacológico , Masculino , Tomografia Computadorizada por Raios X
19.
Materials (Basel) ; 14(24)2021 Dec 10.
Artigo em Inglês | MEDLINE | ID: mdl-34947193

RESUMO

Yield stress parameter derivation was conducted by stress-strain curve analysis on four types of grout injection leakage repair materials (GILRM); acrylic, epoxy, urethane and SPRG grouts. Comparative stress-strain curve analysis results showed that while the yield stress point was clearly distinguishable, the strain ratio of SPRG reached up to 664% (13 mm) before material cohesive failure. A secondary experimental result comprised of three different common component ratios of SPRG was conducted to derive and propose an averaged yield stress curve graph, and the results of the yield stress point (180% strain ratio) were set as the basis for repeated stress-strain curve analysis of SPRGs of up to 15 mm displacement conditions. Results showed that SPRG yield stress point remained constant despite repeated cohesive failure, and the modulus of toughness was calculated to be on average 53.1, 180.7, and 271.4 N/mm2, respectively, for the SPRG types. The experimental results of this study demonstrated that it is possible to determine the property limits of conventional GILRM (acrylic, epoxy and urethane grout injection materials) based on yield stress. The study concludes with a proposal on potential application of GILRM toughness by finite element analysis method whereby strain of the material can be derived by hydrostatic pressure. Comparative analysis showed that the toughness of SPRG materials tested in this study are all able to withstand hydrostatic pressure range common to underground structures (0.2 N/mm2). It is expected that the evaluation method and model proposed in this study will be beneficial in assessing other GILRM materials based on their toughness values.

20.
Eng. sanit. ambient ; Eng. sanit. ambient;26(6): 1069-1077, nov.-dez. 2021. tab, graf
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1350725

RESUMO

RESUMO Os aterros sanitários são obras construídas para o confinamento seguro dos resíduos sólidos e, entre seus elementos de projeto, destaca-se a camada de impermeabilização da cobertura final, frequentemente construída com solo argiloso, que deve, entre outras funções, minimizar ao máximo a infiltração de águas pluviais para o interior do aterro e o fluxo de gases com o meio ambiente. As características físicas, químicas e mineralógicas dos materiais dessa camada devem ser analisadas para a avaliar seu potencial de utilização. O presente trabalho teve como objetivo avaliar o desempenho de argilas expansivas, sujeitas à variação de umidade, como material impermeabilizante de cobertura de aterros sanitários, sendo caracterizadas duas amostras por meio de ensaios geotécnicos. As características foram compatíveis com os requisitos exigidos nas normas consultadas. A parte superior de uma camada de argila compactada foi reproduzida com uma das amostras em um modelo experimental, sujeita à secagem, com observação da formação de trincas e medições do teor de umidade ao longo do tempo e profundidade. A formação de trincas na superfície se iniciou para teores de umidade acima do limite de plasticidade. A aplicação de uma carga hidráulica na superfície após a etapa de secagem resultou em um fechamento das trincas em razão da expansão da argila, indicando eficiência na restrição de entrada de águas pluviais. No entanto, o uso de material expansivo para esse fim deve ser investigado quanto ao seu desempenho em campo, tanto na fase de construção, durante a compactação, quanto de operação, quando estará sujeito às variações climáticas.


ABSTRACT Solid waste landfills are works built to contain solid urban waste, being the most used final disposal method in Brazil. One of the most important components of the project is the final cover, the low hydraulic conductivity layer, with clayey materials, which has the function of minimizing the infiltration of rainwater into the landfill and the entry and exit of gases. The physical, chemical and mineralogical characteristics of clayey materials must be analyzed for potential use as a cover layer. The present work aimed to evaluate the use of clays, with expansive characteristics, subject to water content variations, as cover material in landfills, being characterized two clay samples through geotechnical tests. The characterization indicated samples with characteristics compatible with the requirements demanded by the consulted standards. One of them was used in a laboratory model and reproduced the upper part of a layer of compacted clay, subject to drying on the surface, with observation of the formation of cracks, and with measurements of the water content over time and depth. Cracks on the clay surface occurred during the drying process, starting for water contents above the limit of plasticity of the clay. The application of a hydraulic head on the surface, after the drying step, resulted in cracks closure, due to the expansion of the clay, indicating efficiency in the restriction of rainwater entry. However, the use of expansive material for this purpose should be investigated regarding its performance in the field, both in the construction phase, during compaction, and in operation, subject to climatic variations.

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