[Angiodynamic and optical coupling analysis of skin tissue model under finite pressure].

The pulse amplitude of fingertip volume could be improved by selecting the vascular dense area and applying appropriate pressure above it. In view of this phenomenon, this paper used Comsol Multiphysics 5.6 (Comsol, Sweden), the finite element analysis software of multi-physical field coupling simulation, to establish the vascular tissue model of a single small artery in fingertips for simulation. Three dimensional Navier-Stokes equations were solved by finite element method, the velocity field and pressure distribution of blood were calculated, and the deformation of blood vessels and surrounding tissues was analyzed. Based on Lambert Beer's Law, the influence of the longitudinal compression displacement of the lateral light surface region and the tissue model on the light intensity signal is investigated. The results show that the light intensity signal amplitude could be increased and its peak value could be reduced by selecting the area with dense blood vessels. Applying deep pressure to the tissue increased the amplitude and peak of the signal. It is expected that the simulation results combined with the previous experimental experience could provide a feasible scheme for improving the quality of finger volume pulse signal.

Verification of embedding conditions for FBG sensor into textile product for the development of wearable healthcare sensor.

BACKGROUND: To develop wearable healthcare sensors that use fiber Bragg grating (FBG) sensors, a stretch textile product with an embedded FBG sensor is required. OBJECTIVE: The FBG sensor, which is an optical fiber, was embedded into a textile product following a wavy pattern by using a warp knitting machine. METHODS: When an optical fiber is embedded in a textile product, the effect of the cycle length of wavy pattern and the number of cycles on the optical loss is verified. The shorter the cycle length of the wavy pattern of the optical fiber, and more increase in the number of cycles, the longer the textile product in which the optical fiber is embedded can expand and contract. However, when the cycle length of the wave pattern is 30 mm (shortest), large in optical loss, the pulse wave signal cannot be measured. If the cycle length of the wavy pattern is 50 mm or more, small in optical loss, the pulse wave signal is measured. RESULTS: Compared with a straight pattern embedding FBG sensor, the amplitude value of the pulse wave signal measured with a cycle length of 50 mm is large, therefore the sensor sensitivity in this state is greater. This result is consistent with the measurement sensitivity depending on the angle of installation with respect to the direction of the artery. CONCLUSION: With a cycle length of wavy pattern of 50 mm and 4 cycles, a stretch textile product with an embedded FBG sensor can be fabricated. Pulse wave signals are measured with this textile product, and the development of wearable healthcare sensors is expected.

Verification of Non-Invasive Blood Glucose Measurement Method Based on Pulse Wave Signal Detected by FBG Sensor System.

This paper describes and verifies a non-invasive blood glucose measurement method using a fiber Bragg grating (FBG) sensor system. The FBG sensor is installed on the radial artery, and the strain (pulse wave) that is propagated from the heartbeat is measured. The measured pulse wave signal was used as a collection of feature vectors for multivariate analysis aiming to determine the blood glucose level. The time axis of the pulse wave signal was normalized by two signal processing methods: the shortest-time-cut process and 1-s-normalization process. The measurement accuracy of the calculated blood glucose level was compared with the accuracy of these signal processing methods. It was impossible to calculate a blood glucose level exceeding 200 mg/dL in the calibration curve that was constructed by the shortest-time-cut process. In the 1-s-normalization process, the measurement accuracy of the blood glucose level was improved, and a blood glucose level exceeding 200 mg/dL could be calculated. By verifying the loading vector of each calibration curve to calculate the blood glucose level with a high measurement accuracy, we found the gradient of the peak of the pulse wave at the acceleration plethysmogram greatly affected.