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1.
Braz. J. Biol. ; 83: 1-8, 2023. tab
Artigo em Inglês | VETINDEX, VETINDEX | ID: vti-765505

RESUMO

Ninety days study was conducted in hapas installed in earthen ponds. Fish of an average initial weight (220g) were evenly distributed in triplicate groups within fifteen hapas. Five experimental diets labeled as T1 (25% CP and NRC recommended amino acid level) as control diet, T2 (with 2% low protein and 5% amino acid supplementation), T3 (with 2% low protein and 10% amino acid supplementation), T4 (with 4% low protein and 10% amino acid supplementation) and T5 (with 4% low protein and 20% amino acid supplementation) were prepared. Fish were fed with @3% of their body weight twice a day at 10.00 & 16:00 hour. Significantly higher percent weight gain (420.18 ± 66.84a) and specific growth rate (13499.33±1273.54a) along with improved feed conversion ratio (1.29 ± 0.09b) and hundred percent survivals were recorded during the trial. Furthermore proximate analysis of meat showed significant improvement in the crude protein level (81.77 ± 0.19a) served with diet containing 20% limiting amino acids mixture. Therefore, limiting amino acids can be a source of cost effective feed and use safely in L. rohita diet.(AU)


O estudo de 90 dias foi realizado em hapas instalados em tanques de terra. Peixes com peso inicial médio (220 g) foram distribuídos uniformemente em grupos triplicados em 15 hapas. Cinco dietas experimentais rotuladas como T1 (25% de CP e NRC recomendado nível de aminoácidos) como dieta controle, T2 (com 2% de proteína baixa e 5% de suplementação de aminoácidos), T3 (com 2% de proteína baixa e 10% de suplementação de aminoácidos), T4 (com 4% de baixa proteína e 10% de suplementação de aminoácidos) e T5 (com 4% de baixa proteína e 20% de suplementação de aminoácidos) foram preparadas. Os peixes foram alimentados com 3% do seu peso corporal duas vezes por dia às 10h00 e 16h00. Ganho de peso significativamente maior (420,18 ± 66,84a) e taxa de crescimento específico (13499,33 ± 1273,54a) juntamente com taxa de conversão alimentar melhorada (1, 29 ± 0,09b) e sobrevivência de cem por cento foram registrados durante o ensaio. Além disso, a análise aproximada da carne mostrou melhora significativa no nível de proteína bruta (81,77 ± 0,19a) servida com dieta contendo 20% de mistura de aminoácidos limitantes. Portanto, a limitação de aminoácidos pode ser uma fonte de alimentação econômica e usada com segurança na dieta de L. rohita.(AU)


Assuntos
Animais , Cyprinidae/crescimento & desenvolvimento , Cyprinidae/metabolismo , Dietoterapia/veterinária , Dieta com Restrição de Proteínas/veterinária
2.
Braz. j. biol ; 83: e249422, 2023. tab
Artigo em Inglês | MEDLINE, LILACS, VETINDEX | ID: biblio-1339393

RESUMO

Abstract Ninety days study was conducted in hapas installed in earthen ponds. Fish of an average initial weight (220g) were evenly distributed in triplicate groups within fifteen hapas. Five experimental diets labeled as T1 (25% CP and NRC recommended amino acid level) as control diet, T2 (with 2% low protein and 5% amino acid supplementation), T3 (with 2% low protein and 10% amino acid supplementation), T4 (with 4% low protein and 10% amino acid supplementation) and T5 (with 4% low protein and 20% amino acid supplementation) were prepared. Fish were fed with @3% of their body weight twice a day at 10.00 & 16:00 hour. Significantly higher percent weight gain (420.18 ± 66.84a) and specific growth rate (13499.33±1273.54a) along with improved feed conversion ratio (1.29 ± 0.09b) and hundred percent survivals were recorded during the trial. Furthermore proximate analysis of meat showed significant improvement in the crude protein level (81.77 ± 0.19a) served with diet containing 20% limiting amino acids mixture. Therefore, limiting amino acids can be a source of cost effective feed and use safely in L. rohita diet.


Resumo O estudo de 90 dias foi realizado em hapas instalados em tanques de terra. Peixes com peso inicial médio (220 g) foram distribuídos uniformemente em grupos triplicados em 15 hapas. Cinco dietas experimentais rotuladas como T1 (25% de CP e NRC recomendado nível de aminoácidos) como dieta controle, T2 (com 2% de proteína baixa e 5% de suplementação de aminoácidos), T3 (com 2% de proteína baixa e 10% de suplementação de aminoácidos), T4 (com 4% de baixa proteína e 10% de suplementação de aminoácidos) e T5 (com 4% de baixa proteína e 20% de suplementação de aminoácidos) foram preparadas. Os peixes foram alimentados com 3% do seu peso corporal duas vezes por dia às 10h00 e 16h00. Ganho de peso significativamente maior (420,18 ± 66,84a) e taxa de crescimento específico (13499,33 ± 1273,54a) juntamente com taxa de conversão alimentar melhorada (1, 29 ± 0,09b) e sobrevivência de cem por cento foram registrados durante o ensaio. Além disso, a análise aproximada da carne mostrou melhora significativa no nível de proteína bruta (81,77 ± 0,19a) servida com dieta contendo 20% de mistura de aminoácidos limitantes. Portanto, a limitação de aminoácidos pode ser uma fonte de alimentação econômica e usada com segurança na dieta de L. rohita.


Assuntos
Animais , Cyprinidae , Ração Animal/análise , Suplementos Nutricionais , Dieta/veterinária , Aminoácidos
3.
Fam Process ; 61(1): 213-229, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-34643278

RESUMO

There are a variety of educational interventions for families who have a relative with a mental health disorder. However, for those with one or more emotion dysregulation disorders, there are limited options. This article reports on the results of a pilot project using a quasi-experimental design with a sample of 270 (intervention = 217, control = 53) to assess an intervention, Getting Off the Emotional Roller Coaster Skill-Building Family Education Course (GOER Family Course), for families coping with and managing emotion regulation disorders in a loved one which are often misdiagnosed or co-occurring. This intervention was effective in reducing caregiver burden [F(1, 120) = 12.25, p = 0.001], while improving attitudes, knowledge, and skills [F(1, 170) = 6.16, p = 0.014]. It fills an important gap in available resources for families faced with challenges and responsibilities that these disorders can present, especially when inaccurately diagnosed or receiving ineffective treatment. While there is a need for further research and adaptation to virtual learning, the preliminary results show positive effects.


Existen varias intervenciones educativas para las familias que tienen un familiar con un trastorno de salud mental. Sin embargo, para aquellos que padecen uno o más trastornos de desregulación emocional, existen pocas opciones. En este artículo se informan los resultados de un proyecto piloto usando un diseño cuasiexperimental con una muestra de 270 personas (intervención=217, de referencia=53) para evaluar una intervención llamada Bajarse de la montaña rusa emocional: curso de capacitación familiar para el desarrollo de habilidades (Curso familiar GOER, por sus siglas en inglés), orientado a familias que enfrentan y manejan trastornos de regulación emocional en un ser querido, los cuales generalmente están mal diagnosticados o son concomitantes. Esta intervención fue eficaz para reducir el agobio de los cuidadores [F (1,120 )=12.25, p=.001] y a la vez mejorar las actitudes, el conocimiento y las habilidades [F (1,170)=6.16, p=.014]. Además, llena un vacío importante en los recursos disponibles para las familias que enfrentan las dificultades y las responsabilidades que estos trastornos pueden presentar, especialmente cuando tienen un diagnóstico impreciso o reciben un tratamiento ineficaz. Si bien es necesario continuar investigando y adaptarse a la enseñanza virtual, los resultados preliminares indican efectos positivos.


Assuntos
Transtorno Bipolar , Transtorno Depressivo Maior , Adaptação Psicológica , Adulto , Transtorno Depressivo Maior/terapia , Humanos , Personalidade , Projetos Piloto
4.
Estud. Interdiscip. Psicol ; 12(3): 91-118, set-dez.2021.
Artigo em Português | LILACS | ID: biblio-1359085

RESUMO

Este artigo discorre sobre adolescentes que foram alfabetizados em prazos bastante curtos, quando internados para cumprimento de medida socioeducativa, após terem fracassado recorrentemente no curso regular de escolarização. A investigação buscou compreender os sentidos do êxito tardio em ambiente de privação de liberdade. Participaram do estudo 15 adolescentes de quatro unidades da Fundação CASA, que não possuíam competência de leitura e escrita quando de sua internação. Para tanto, os adolescentes foram entrevistados; alguns produziram desenhos, que foram examinados. O trabalho amparou-se na psicanálise, centralmente em Donald W. Winnicott. Conclui-se que há necessidade de o ambiente educativo se apresentar como espaço continente para as dificuldades e para processos identificatórios, podendo apresentar-se como um "alojamento" em que o "paradoxo limite e espaço" e as ressignificações ganham o sentido de amparo psíquico que, dentre outras coisas, interfere na aprendizagem e pode ou não chegar a ser curativo (Au).


This article discusses adolescents who were taught to read and write within a very short time when interned in compliance with a socio-educational measure, after recurrent failures on regular school courses. The investigation seeks to understand the meanings of late success in an environment of freedom deprivation. 15 adolescents from four Fundação Casa units participated, who were unable to read and write on their internment. To this end, the adolescents were interviewed and some produced drawings, which were examined. The work was supported by psychoanalysis, especially Donald W. Winnicott. It was concluded that there is a need for the educational environment to present itself as a containing space for difficulties and for identificatory processes, able to show itself as "lodging" where the "limit and space paradox" and resignifications gain the meaning of psychic support which, among other things, affects learning and may or may not be ultimately curative (AU).


Este artículo discurre sobre los adolescentes que han sido alfabetizados en plazos bastante cortos cuando fueron internados para el cumplimiento de una medida socioeducativa, después de que hubiesen fracasado recurrentemente en el recorrido normal de la escolarización. La investigación trató de comprender los sentidos del éxito tardío en un entorno de privación de la libertad. Participaron del estudio quince adolescentes de cuatro unidades de la Fundação CASA ("Fundación CASA"), los cuales no poseían competencia de lectura y escritura cuando fueron internados. Para ello, se entrevistaron a los adolescentes; algunos produjeron dibujos, los cuales fueron examinados. El trabajo se amparó en el psicoanálisis, sobre todo en Donald W. Winnicott. Se concluyó que hay la necesidad de que el entorno educativo se presente como un espacio continente para las dificultades y para los procesos identificatorios, apareciendo como un "alojamiento" en que la "paradoja límite y espacio" y las resignificaciones ganan el sentido de auxilio psíquico. Eso, entre otras cosas, interfiere en el aprendizaje y puede o no llegar a ser curativo (AU).


Assuntos
Humanos , Psicanálise , Alojamento , Liberdade , Aprendizagem , Transtorno da Personalidade Antissocial , Psicologia Educacional , Meio Ambiente
5.
Eur J Psychotraumatol ; 12(1): 1934300, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34408815

RESUMO

Background: Childhood maltreatment and difficulties in emotion regulation are common in patients with Borderline Personality Disorder (BPD) and Depressive Disorders (DD). Objective: This study examines differences between patients with BPD and patients with DD, regarding childhood maltreatment and difficulties in emotion regulation as well as the mediating effect of different aspects of emotion regulation deficits on the association between childhood maltreatment and BPD-symptoms. Method: A total of 305 participants, 177 with BPD and 128 with DD completed an assessment including the Childhood Trauma Questionnaire (CTQ), the Emotion Regulation Scale (DERS), the Brief Symptom Inventory (BSI), and the Structured Clinical Interview for DSM-IV (SCID). Data was analyzed using multiple analyses of variances and mediation analyses. Results: Patients with BPD reported more childhood maltreatment and more difficulties in emotion regulation than patients with DD. When general symptom severity, age, and gender were included in the analysis as covariates only group differences regarding 'impulse control difficulties' (F(1,299) = 38.97, p < .001, ηp 2 = .115), 'limited access to emotion regulation strategies' (F(1,299) = 4.66, p = .032, ηp 2 = .015), and 'lack of emotional clarity' (F(1,299) = 9.38, p = .002, ηp 2 = .030) remained statistically significant. A mediation analysis, including above-mentioned covariates, indicated an association between emotional abuse and BPD-symptoms, which was mediated by difficulties in emotion regulation (indirect effect B = .012, 95% CI [.001; .031], R2 = .429). Subscale analyses revealed 'impulse control difficulties' as the aspect of difficulties in emotion regulation that has the greatest impact on this association (B = .021, 95% CI [.003; .045]). Conclusions: Patients with BPD display more childhood maltreatment and difficulties in emotion regulation than patients with DD. Difficulties in emotion regulation, especially difficulties in impulse control, seem to play an important role in the association between childhood emotional abuse and BPD-symptoms.


Antecedentes: El maltrato infantil y las dificultades en la regulación emocional son frecuentesw en pacientes con trastorno límite de personalidad (TLP) y pacientes con trastornos depresivos (TD).Objetivo: Este estudio examina las diferencias entre pacientes con TLP y pacientes con TD, en cuanto al maltrato infantil y las dificultades en la regulación de las emociones, así como el efecto mediador de diferentes aspectos de los déficits en la regulación de las emociones sobre la asociación entre el maltrato infantil y los síntomas del TLP.Método: Un total de 305 participantes, 177 pacientes con TLP y 128 pacientes con TD completaron una evaluación que incluyó el Cuestionario de Trauma Infantil (CTQ), la Escala de Regulación de las Emociones (DERS), el Inventario Breve de Síntomas (BSI) y la Entrevista Clínica Estructurada para DSM-IV (SCID). Los datos se analizaron mediante múltiples análisis de variaciones y análisis de mediación.Resultados: Los pacientes con TLP informaron más maltrato infantil y más dificultades en la regulación de las emociones que los pacientes con TD. Cuando la gravedad de los síntomas generales, la edad y el sexo se incluyeron en el análisis como covariables, solo las diferencias de grupo con respecto a las 'dificultades de control de impulsos' (F (1.299) = 38,97, p <.001, ηp 2 = .115), 'acceso limitado a estrategias de regulación de las emociones '(F (1,299) = 4.66, p = .032, ηp 2 = .015) y' falta de claridad emocional '(F (1,299) = 9.38, p = .002, ηp 2 = .030) permanecieron estadísticamente significativas. Un análisis de mediación, incluidas las covariables antes mencionadas, indicó una asociación entre el abuso emocional y los síntomas del TLP, que fue mediada por dificultades en la regulación de las emociones (efecto indirecto B = .012, IC del 95% [.001; .031], R2 =. 429). Los análisis de subescalas revelaron "dificultades de control de impulsos" como el aspecto de las dificultades en la regulación de las emociones que tiene el mayor impacto en esta asociación (B = .021, IC del 95% [.003; .045]).Conclusiones: Los pacientes con TLP presentan más maltrato infantil y dificultades en la regulación de las emociones que los pacientes con TD. Las dificultades en la regulación de las emociones, especialmente las dificultades en el control de los impulsos, parecen jugar un papel importante en la asociación entre el abuso emocional infantil y los síntomas del TLP.


Assuntos
Sobreviventes Adultos de Maus-Tratos Infantis/estatística & dados numéricos , Transtorno da Personalidade Borderline/epidemiologia , Transtorno Depressivo Maior/epidemiologia , Regulação Emocional/fisiologia , Adulto , Criança , Humanos , Comportamento Impulsivo/fisiologia , Inquéritos e Questionários/estatística & dados numéricos
6.
Rev. bras. psicanál ; 55(2): 61-72, abr.-jun. 2021. ilus
Artigo em Português | LILACS-Express | LILACS, Index Psicologia - Periódicos | ID: biblio-1288979

RESUMO

O artigo apresenta a captura no circuito da dor como um modelo para a escuta e o manejo de situações clínicas em que o enquadre analítico esbarra na tendência imperiosa à redução de tensão própria da fuga da dor, num esforço de inativar o traumático. A busca de fundamentos metapsicológicos resgata o conceito de dor e de masoquismo erógeno primário, a fim de interrogar as condições analíticas para favorecer uma mínima ligação capaz de propiciar a suportabilidade da inevitável tensão da existência psíquica.


The article presents the capture in the pain circuit as a model for listening and handling clinical situations in which the analytical setting comes up against the imperative tendency to reduce tension inherent in the escape of pain, in an effort to inactivate the traumatic one. The search for metapsychological foundations rescues the concept of pain and primary erogenous masochism, to interrogate the analytical conditions to favor a minimal connection capable of supporting the inevitable tension of the psychic existence.


El artículo presenta la captura en el circuito del dolor como modelo metasicológico de escucha y manejo de situaciones clínicas en las que el marco analítico choca con la tendencia imperativa para reducir la tensión inherente al escape del dolor, en un esfuerzo por inactivar lo traumático. La búsqueda de fundamentos metasicológicos rescata el concepto de dolor y masoquismo erógeno primario, para cuestionar las condiciones analíticas y así favorecer una relación mínima capaz de favorecer la soportabilidad de la inevitable tensión de la existencia psíquica.


L'article présente la capture dans le circuit de la douleur en tant qu'un modèle d'écoute et de gestion de situations cliniques dans lesquelles le cadre analytique se heurte à la tendance impérative à réduire la tension propre à la fuite de la douleur, dans un effort pour inactiver le traumatisant. La recherche de fondements de métapsychologie récupère le concept de douleur et de masochisme érogène primaire, afin d'interroger les conditions analytiques de manière à favoriser une liaison minimale susceptible de favoriser la capacité de supporter l'inévitable tension de l'existence psychique.

7.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33840500

RESUMO

INTRODUCTION: The spectrum of suicidal behaviour (SB) is nuclear in the clinic and management of borderline personality disorder (BPD). The pathological personality traits of BPD intervene as risk factors for SB in confluence with other clinical and sociodemographic variables associated with BPD. The objective of this work is to evaluate the specific personality traits of BPD that are related to SB. METHODS: A cross-sectional, observational and retrospective study was carried out on a sample of 134 patients diagnosed with BPD according to DSM-5 criteria. The Millon-II, Zuckerman-Kuhlman and Barrat questionnaires were used to assess different personality parameters. Variable comparisons were made using the χ2 test and the Student's t-test. The association between variables was analysed using multivariate logistic regression. RESULTS: Statistically significant differences were observed between SB and related factors and the neuroticism-anxiety dimension in the Zuckerman-Kuhlman test. It is also significantly related to the phobic and antisocial subscale of the Millon-II. Impulsivity measured with the Zuckerman-Kuhlman and Barrat tests does not appear to be related to SB. CONCLUSIONS: The results presented raise the role of phobic, antisocial and neuroticism traits as possible personality traits of BPD related to SB, suggesting an even greater importance within the relationship between BPD and SB than that of impulsivity. Looking to the future, longitudinal studies would increase the scientific evidence for the specified findings.

8.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33734997

RESUMO

The clinical difference between bipolar disorder and borderline personality disorder has always been a diagnostic challenge, especially with type II bipolar disorder and subthreshold symptoms, opening a diagnostic bias with the consequent repercussions of inappropriate treatment. Both pathologies are often misdiagnosed initially. The objective of this article is to emphasise the main clinical differences between the two pathologies. We present the case of a patient with a long history of psychiatric symptoms that started in childhood, with considerable functional impairment, who met the criteria for both disorders, pointing to comorbidity. During follow-up, she responded favourably to psychotropic drugs, pushing the diagnosis towards the bipolar spectrum, due to the notable improvement. However, comorbidity should not be neglected due to its high presentation.

9.
Can J Hosp Pharm ; 74(1): 57-69, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33487656

RESUMO

BACKGROUND: The availability of generic versions of bortezomib raises questions about the reliability of extrapolating stability data from one brand to another. OBJECTIVE: To evaluate the stability of bortezomib formulations available from Janssen, Teva Canada, Actavis Pharma, Dr. Reddy's Laboratories, Apotex, and MDA, reconstituted with 0.9% sodium chloride (normal saline) to produce solutions of either 1.0 or 2.5 mg/mL and stored over at least 21 days under refrigeration (4°C) or at room temperature (either 23°C or 25°C) in the manufacturer's original glass vials or in polypropylene syringes. METHODS: On study day 0, solutions with concentration 1.0 mg/mL or 2.5 mg/mL of the Teva, Actavis, Dr. Reddy's, Apotex, and MDA generic formulations were prepared. Three units of each type of container (glass vials and syringes) were stored at 4°C and 3 units at room temperature. Concentration and physical inspection were completed on at least 8 study days (including day 0) over a 21- to 84-day study period. Bortezomib concentrations were determined by a validated stability-indicating liquid chromatographic method with ultraviolet detection. The end point of these studies was the time to reach 90% of the initial concentration (T-90) with 95% confidence, which is expressed as "T-9095%CI", where CI refers to the confidence interval. In addition to estimating the T-9095%CI, differences in stability among products from all manufacturers were compared using multiple linear regression. Previously published data for the Janssen product were included in the overall comparisons. RESULTS: In all of the studies, the analytical method separated degradation products from bortezomib, such that the concentration of bortezomib was measured specifically, accurately (deviations < 2.5%), and reproducibly (average replicate error 2.5%). During all studies, solutions retained more than 94% of the initial concentration at 4°C. The T-9095%CI exceeded the study period for all formulations under all combinations of concentration, container, and temperature, except the 84-day study for the MDA product. Multiple linear regression showed no significant differences among manufacturers (p = 0.57). CONCLUSIONS: In this study, formulations of bortezomib currently marketed in Canada (by Janssen, Teva Canada, Actavis Pharma, Dr. Reddy's Laboratories, Apotex, and MDA) were pharmaceutically equivalent and interchangeable. Given that there was no difference in stability related to manufacturer, nominal concentration, or container, we conclude that these formulations are physically and chemically stable for at least 35 days under refrigeration and at least 25 days at room temperature.


CONTEXTE: La disponibilité de versions génériques de bortezomib soulève des questions relatives à la fiabilité de l'extrapolation des données concernant la stabilité d'une marque à l'autre. OBJECTIF: Évaluer la stabilité des formules de bortezomib de Janssen, de Teva Canada, d'Actavis Pharma, des Laboratoires du Dr Reddy, d'Apotex et de MDA, reconstituées avec 0,9 % de chlorure de sodium (solution saline normale) pour produire des solutions de 1 ou de 2,5 mg/mL et réfrigérées au moins 21 jours à 4 °C ou à température ambiante (23 °C ou 25 °C), dans des fioles en verre du fabricant ou dans des seringues en polypropylène. MÉTHODES: La préparation des solutions avec une concentration de 1 mg/mL ou 2,5 mg/mL des formules génériques de Teva, d'Actavis, du Dr Reddy, d'Apotex et de MDA a eu lieu le jour 0 de l'étude. Trois unités de chaque contenant (fioles en verre et seringues) étaient stockées à 4 °C et 3 unités, à température ambiante. L'inspection de la concentration et l'inspection physique ont été réalisées pendant au moins 8 jours (y compris le jour 0) de l'étude qui a duré de 21 à 84 jours. Les concentrations de bortezomib ont été déterminées par une méthode chromatographique liquide validée, indiquant la stabilité à l'aide d'une détection par rayons ultraviolets. Le point final de ces études était le temps nécessaire pour que le produit atteigne 90 % de la concentration initiale (T-90) avec un seuil de confiance de 95 %, exprimé par T-90IC 95 %, IC indiquant l'intervalle de confiance. En plus de l'estimation du T-90IC 95 %, les différences de stabilité des produits de tous les fabricants ont été comparées à l'aide d'une régression linéaire multiple. Les données publiées précédemment sur le produit Jansen sont incluses dans les comparaisons globales. RÉSULTATS: La méthode analytique de toutes les études qui ont été menées a séparé les produits de dégradation du bortezomib de telle manière que la concentration était mesurée de manière spécifique, précise (déviations < 2,5 %) et reproductible (erreur de réplique 2,5 %). Tout au long des études, les solutions ont retenu plus de 94 % de la concentration initiale à 4 °C. Le T-90IC 95 % de toutes les formules dans toutes les combinaisons de concentration, de contenant et de température, dépassait la durée des études, à l'exception du produit MDA dans l'étude de 84 jours. La régression linéaire multiple n'a indiqué aucune différence importante parmi les fabricants (p = 0,57). CONCLUSIONS: Dans cette étude, les formules de bortezomib actuellement commercialisées au Canada (par Janssen, Teva Canada, Actavis Pharma, les Laboratoires du Dr Reddy, Apotex et MDA) étaient équivalentes et interchangeables d'un point de vue pharmaceutique. Puisqu'aucune différence de stabilité, de concentration nominale ou de contenant liée à l'un ou l'autre des fabricants n'a été révélée, nous concluons que ces formules sont physiquement et chimiquement stables pendant au moins 35 jours sous réfrigération et au moins 25 jours à température ambiante.

10.
Fam Process ; 60(1): 134-144, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-32304101

RESUMO

Carers of patients with borderline personality disorder (BPD) experience high levels of distress. Several studies have been carried out on interventions designed to decrease their burden. However, the evidence from these studies has not been summarized. The objective of this work is to explore the clinical utility of interventions developed for family members of patients with BPD. A systematic review was conducted following the PRISMA guidelines (registration number CRD42018107318), including psychological interventions focused on relatives of patients with BPD. The following databases were used: PsycINFO, PubMed, EBSCOhost, and Web of Science. Two independent researchers reviewed the studies to determine whether the eligibility criteria were met. A total of 2,303 abstracts were identified. After duplicates had been removed, 1,746 studies were screened. Finally, 433 full-text articles were reviewed, yielding 11 studies that satisfied the inclusion criteria. Results show that these interventions with different clinical formats and settings are effective. The quality of the included studies varies, and the empirical support for these programs is still preliminary. The results help to establish a general framework for interventions specifically developed for family members of patients with BPD, but additional efforts should be made to improve the methodological quality of this field of research and more solidly determine the utility of these interventions. Given the paucity of data so far, this information may open up new lines of research to improve the effectiveness of future programs for carers of patients with BPD and help to reduce their burden.


Los familiares de pacientes con trastorno límite de la personalidad (TLP) experimentan elevados niveles de estrés. Se han llevado a cabo varios estudios sobre intervenciones diseñadas para disminuir su carga. Sin embargo, los datos obtenidos de estos estudios no se han expuesto. El objetivo de este trabajo es explorar la utilidad clínica de las intervenciones desarrolladas para los familiares de los pacientes con TLP. Se realizó una revisión sistemática siguiendo las directrices de PRISMA (número de registro CRD42018107318), que incluyó intervenciones psicológicas centradas en los familiares de los pacientes con TLP. Se utilizaron las siguientes bases de datos: PsycINFO, PubMed, EBSCOhost, y Web of Science. Dos investigadores independientes revisaron los estudios para determinar si se cumplían los criterios de elegibilidad. Se identificaron un total de 2303 resúmenes. Después de extraer los duplicados, se evaluaron 1746 estudios. Finalmente, se revisaron 433 artículos de texto completo, lo que dio lugar a 11 estudios que cumplían los criterios de inclusión. Los resultados demuestran que estas intervenciones con diferentes formatos y orientaciones clínicas son eficaces. La calidad de los estudios incluidos varía, y el apoyo empírico para estos programas es todavía preliminar. Los resultados contribuyen a establecer un marco general para las intervenciones desarrolladas específicamente para los familiares de los pacientes con TLP, pero se deberían realizar esfuerzos adicionales para mejorar la calidad metodológica de este campo de investigación y determinar con mayor solidez la utilidad de estas intervenciones. Dada la escasez de datos hasta el momento, esta información puede abrir nuevas líneas de investigación para mejorar la eficacia de los futuros programas para los cuidadores de los pacientes con TLP y ayudar a reducir su carga.


Assuntos
Transtorno da Personalidade Borderline , Transtorno da Personalidade Borderline/terapia , Cuidadores , Atenção à Saúde , Família , Humanos
11.
Fam Process ; 60(3): 772-787, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-33010045

RESUMO

Despite the fact that family involvement is encouraged in early interventions for borderline personality disorder (BPD), there is a limited knowledge on the experience of caring for adolescents with BPD. This is an exploratory retrospective study nested within a randomized controlled trial that compared mentalization-based treatment (MBT) in groups to treatment as usual for adolescents with BPD. Caregivers received six MBT-Parents sessions or standard care over one year. Three months after end of treatment (EOT), 75 caregivers (35 in MBT, 40 in TAU) filled out the Burden Assessment Scale, and 71 (34 in MBT, 37 in TAU) the Family Satisfaction Survey. The adolescents filled out the Borderline Personality Features Scale for Children at baseline and after twelve months at EOT. We tested whether caregiver demographics, adolescents' severity of BPD, treatment and adolescents' dropout from treatment predicted levels of caregiver burden and satisfaction with treatment. The caregivers reported high levels of burden on the BAS (M = 40.3, SD = 12.2). Our study suggests that higher BPD severity at EOT among the adolescents predicted caregiver burden (p = .03), whereas higher baseline BPD severity predicted satisfaction with treatment (p = .04) and that biological mothers could be more burdened than other types of caregivers but also might be more satisfied with treatment. Treatment and adolescents' dropout from treatment were not related to caregiver burden or satisfaction with treatment. To help inform future research and to devise appropriate interventions for caregivers and adolescents with BPD, it is important to identify possible predictors of caregiver burden. The results of this initial exploratory study indicate that caregivers (and particularly biological mothers) of adolescents with more severe levels of BPD could be particularly vulnerable toward feelings of burden and therefore are in need of support.


A pesar del hecho de que se recomienda la participación familiar en las primeras intervenciones para el trastorno límite de la personalidad (TLP), se sabe muy poco sobre la experiencia de cuidar a adolescentes con TLP. El presente es un estudio retrospectivo exploratorio enmarcado en un ensayo controlado aleatorizado que compara el tratamiento basado en la mentalización (TBM) en grupos con el tratamiento habitual (TH) para adolescentes con TLP. Los cuidadores recibieron seis sesiones de TBM para padres o la atención normal durante un año. Tres meses después del final del tratamiento, 75 cuidadores (35 en TBM, 40 en TH) completaron la Escala de Evaluación del Agobio (Burden Assessment Scale), y 71 (34 en TBM, 37 en TH) la Encuesta de Satisfacción Familiar (Family Satisfaction Survey). Los adolescentes completaron la Escala de Características de la Personalidad Límite para Niños (Borderline Personality Features Scale for Children) en el momento basal y después de doce meses al final del tratamiento. Evaluamos si las características demográficas de los cuidadores, la intensidad del TLP de los adolescentes, el tratamiento y la deserción del tratamiento por parte de los adolescentes predijeron niveles de agobio en los cuidadores y de satisfacción con el tratamiento. Los cuidadores informaron niveles altos de agobio en la Escala de Evaluación del Agobio (M = 40.3, DT= 12.2). Nuestro estudio indica que una mayor intensidad del TLP al final del tratamiento entre los adolescentes predijo el agobio del cuidador (p = .03), mientras que una mayor intensidad del TLP en el momento basal predijo la satisfacción con el tratamiento (p = .04), y que las madres biológicas podrían estar más agobiadas que otros tipos de cuidadores, pero también podrían estar más satisfechas con el tratamiento. El tratamiento y la deserción del tratamiento por parte de los adolescentes no estuvieron relacionados con el agobio del cuidador ni con la satisfacción con el tratamiento. Con el fin de contribuir a ampliar futuras investigaciones y de idear intervenciones adecuadas para cuidadores y adolescentes con TLP, es importante reconocer posibles predictores del agobio del cuidador. Los resultados de este estudio exploratorio inicial indican que los cuidadores (y particularmente las madres biológicas) de los adolescentes con niveles más intensos de TLP podrían ser particularmente vulnerables hacia sentimientos de agobio y, por lo tanto, necesitan apoyo.


Assuntos
Transtorno da Personalidade Borderline , Cuidadores , Adolescente , Transtorno da Personalidade Borderline/terapia , Criança , Humanos , Satisfação Pessoal , Estudos Retrospectivos , Resultado do Tratamento
12.
Can J Psychiatry ; 66(3): 306-312, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-32799647

RESUMO

OBJECTIF: Disposer d'outils de dépistage valides pour évaluer le trouble de la personnalité limite est essentiel en pratique clinique et en recherche. Parmi les outils existants, le questionnaire sur la personnalité limite (BPQ) présente plusieurs qualités. Cependant, il n'existe pas de version française et il n'a pas été validé avec des adultes dans un échantillon clinique. Les objectifs de cette étude étaient : 1) traduire le BPQ en français; 2) mesurer la validité convergente, prédictive et discriminante, la cohérence interne et la fidélité test-retest. MÉTHODE: Les recommandations de Streiner, Norman et Cairney (2014) sur la traduction d'évaluations ont été suivies. Quarante adultes référés à un programme spécialisé en troubles de la personnalité ont participé à l'étude. Pour évaluer la validité du BPQ français, le questionnaire SCID-II (entrevue et auto-évaluation) fut administré et le diagnostic psychiatrique fut établi par un psychiatre à l'insu. RÉSULTATS: Aucune modification majeure n'a été apportée au BPQ français. Les analyses ont montré une cohérence interne élevée (α = 0,84), une bonne fidélité test-retest (r = 0,77), une discrimination significative avec le trouble de la personnalité schizotypique (r = -0,31; p < 0,05), une convergence significative avec le SCID-II (r = 0,72) et une validité prédictive significative du diagnostic psychiatrique (p < 0,01). CONCLUSIONS: La version française du BPQ présente des qualités psychométriques prometteuses à un usage auprès des personnes ayant un trouble de la personnalité limite.


Assuntos
Personalidade , Humanos , Inquéritos e Questionários
13.
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1280608

RESUMO

ABSTRACT OBJECTIVE To estimate the maximum theoretical daily intake of pesticides potentially consumed, chronically, by the Brazilian population. METHOD By using data from the food consumption section of the 2008-2009 Household Budget Survey to characterize the population diet, a database was built to group the foods based on the NOVA classification. Considering the maximum residue limit values of each pesticide authorized in the country until 2016, the limits of all consumed foods were added and multiplied by the amount consumed, resulting in the maximum theoretical intake index, which was compared with the acceptable daily intake. RESULTS The results show that, of the 283 pesticides considered in the database, 71 (25%) compounds had estimates of zero intake, 144 compounds (50.8%) reached acceptable daily intake values and 68 compounds (24%) showed median intake that exceeded the acceptable daily value. The pesticide intake estimation according to the different regions of the country showed a variation in the amount of compounds that exceeded the acceptable daily intake (48 to 69 substances) due to the different consumption patterns. The categories of products that most exceeded the limits were the insecticides, herbicides and fungicides. CONCLUSION The application of this methodology is valid for the first step in risk assessment, but the resulting values may be different from the actual exposure since they do not include other factors, such as the combined use of pesticides or unauthorized products. The importance of developing research on specific national food consumption data in a systematic way is emphasized, which generates data and analyses that allow a detailed risk assessment.


RESUMO OBJETIVO Estimar a ingestão diária máxima teórica dos agrotóxicos potencialmente consumidos, de forma crônica, pela população brasileira. MÉTODO Utilizando os dados do bloco de consumo alimentar da Pesquisa de Orçamentos Familiares de 2008-2009 para caracterização da dieta da população, foi construído um banco de dados agrupando os alimentos com base na classificação NOVA. Considerando os valores de limite máximo de resíduos de cada agrotóxico autorizado no país até o ano de 2016, foram somados os limites de todos os alimentos consumidos, multiplicados pela quantidade consumida, gerando o índice de ingestão teórica máxima, que foi comparado com a ingestão diária aceitável. RESULTADOS Os resultados mostram que dos 283 agrotóxicos considerados no banco de dados, 71 compostos tiveram estimativas de ingestão zero (25%), 144 compostos (50,8%) atingiram aos valores de ingestão diária aceitável e 68 compostos (24%) apresentaram mediana de ingestão que excedeu o valor diário aceitável. Quando realizada a estimativa de ingestão de agrotóxicos discriminando as distintas regiões do país, houve variação (entre 48 e 69 substâncias) na quantidade de compostos que excederam a ingestão diária aceitável devido aos diferentes padrões de consumo da população. As categorias dos produtos que mais excederam as estimativas são inseticidas, herbicidas e fungicidas. CONCLUSÃO A aplicação dessa metodologia é válida para o primeiro passo na avaliação de risco, porém os valores resultantes podem ser diferentes da exposição real por não englobar outros fatores, como o uso combinado de agrotóxicos ou de produtos de uso não autorizado. É ressaltada a importância do desenvolvimento de pesquisas de dados específicos de consumo de alimentos nacionais de forma sistemática, gerando dados e análises que viabilizem uma avaliação pormenorizada sobre riscos.


Assuntos
Humanos , Praguicidas , Resíduos de Praguicidas/análise , Brasil , Contaminação de Alimentos/análise , Medição de Risco , Ingestão de Alimentos
14.
Artigo em Espanhol | LILACS, BIMENA | ID: biblio-1284619

RESUMO

A pesar que el número de accidentes de tránsito que involucran a conductores ebrios se ha disparado y que los legisladores tienen una gran presión para encontrar una solución razonable a la cuestión de la conducción bajo los efectos del alcohol especialmente en lo que respecta a los límites máximos permitidos, esa relación entre lo jurídico y lo científico, no siempre se concreta. El examen para la determinación de alcohol en muestras biológicas que se realiza en los laboratorios de Toxicología Forense de la Dirección de Medicina Forense fue validado y acreditado. Este proceso de validación permitió observar que el valor referido en la Ley de Penalización de la Embriaguez Habitual señala valores que podrían indicar un error en la aplicación de las unidades y de no ser así, dicho valor no sería significativo en cuanto a la determinación y cuantificación del etanol por la metodología actualmente utilizada en los laboratorios. La importancia del asesoramiento técnico científico para el uso adecuado de unidades y valores de referencia es indispensable para una interpretación objetiva de nuestra legislación y facilita el punto de unión entre la ciencia forense y la ciencia jurídica...(AU)


Assuntos
Humanos , Intoxicação Alcoólica , Alcoolismo , Regulamentação Governamental , Alcoólicos/legislação & jurisprudência
15.
Rev Colomb Psiquiatr (Engl Ed) ; 49(4): 293-296, 2020.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-33328023

RESUMO

Diagnosing borderline personality disorder during adolescence is usually controversial. In this paper we present a clinical case in which an outline of the main characteristics of borderline personality disorder during adolescence is summarised. The need of taking into consideration the precursor characteristics of borderline personality disorder in young people is also highlighted. At the same time, other significant behavioural disorders found in young people are emphasized as possible forerunners of a borderline personality disorder diagnosis. Finally, we insist upon the need to implement early intervention programmes for these patients based on current models.


Assuntos
Transtorno da Personalidade Borderline/diagnóstico , Transtornos do Comportamento Infantil/diagnóstico , Psicoterapia/métodos , Adolescente , Transtorno da Personalidade Borderline/terapia , Transtornos do Comportamento Infantil/terapia , Diagnóstico Diferencial , Feminino , Humanos
16.
Tese em Português | VETTESES | ID: vtt-222126

RESUMO

MÜLLER, A. F. Viabilidade dos fios de poliamida nacional e importado como alternativa para a técnica de TightRope modificada no tratamento de insuficiência do ligamento cruzado cranial espontâneo em cães. 2020. 68p. Dissertação (mestrado) Faculdade de Zootecnia e Engenharia de Alimentos, Universidade de São Paulo, Pirassununga, 2020. O ligamento cruzado cranial é um dos principais responsáveis pela estabilidade da articulação femorotibiopatelar. Quando rompido ou lacerado (insuficiente), ele proporciona instabilidade da tíbia em relação ao fêmur, levando à claudicação e, também, à doença articular degenerativa. A técnica de TightRope é um método de estabilização extracapsular que emprega fita ultrapolietileno resistente, com âncoras confeccionadas em titânio, que têm como objetivo anular o movimento de gaveta cranial e de rotação interna da tíbia. A fim de se verificar a viabilidade dos fios de poliamida (náilon) como alternativa à fita de ultrapolietileno, estes foram analisados por meio de ensaios mecânicos de tensão, citotoxicidade indireta, por microscopia eletrônica de varredura (MEV) e pela espectroscopia no infravermelho (IV). Os fios testados foram acomodados em um dispositivo, desenvolvido para esta finalidade, e esterilizado em autoclave à 121°C por 15 minutos. Os resultados revelaram que o dispositivo de acomodação, se mostrou eficiente na manutenção do comprimento e diâmetro dos fios autoclavados. Por meio dos ensaios mecânicos de tensão foi possível obter o limite elástico dos fios e assim relacionar o seu diâmetro com o peso do cão com ILCCr. A espectroscopia no IV não indicou alteração molecular da poliamida e o teste de citotoxicidade indireta revelou que o fio de poliamida importado é citotóxico a linhagem celular testada e por isso seu uso in vivo não é indicado. Portanto, o fio de náilon de pesca nacional autoclavado é uma alternativa viável para o tratamento da ILCCr, de baixo custo, fácil aquisição e que pode ser utilizado para outros tipos de cirurgias articulares e em áreas da medicina veterinária que necessitem de fios mais resistentes.


MÜLLER, A. F. Viability of national and imported polyamide threads as an alternative to the modified TightRope technique for the treatment of spontaneous cranial cruciate ligament insufficiency in dogs. 2020. 68p. M.Sc. Dissertation Faculdade de Zootecnia e Engenharia de Alimentos, Universidade de São Paulo, Pirassununga, 2020. The cranial cruciate ligament is one of the main responsible for the femorotibiopatellar joint stability. When ruptured or lacerated (insufficient), it provides instability of the tibia relative to the femur, leading to lameness and also to degenerative joint disease. The TightRope is an extracapsular stabilization technique in which a resistant ultrapolethylene tape, secured with endobuttons made of titanium, aims to prevent the cranial drawer movement and the tibial internal rotation. To check the polyamide (nylon) threads viability as an alternative to the ultrapolethylene tape, these were analyzed employing mechanical stress tests, indirect cytotoxicity assessment, scanning electron microscopy (SEM), and by infrared spectroscopy (IR). The tested threads were accommodated in a device, developed for this purpose, and steam-sterilized at 120°C for 15 minutes. The results revealed that the accommodation device created was efficient in maintaining the length and diameter of the steam-sterilized threads. Through the mechanical stress tests, it was possible to obtain the threads elastic limits and thus to relate its diameter to the weight of the dog with cranial cruciate ligament insufficiency (CCLI). The IR spectroscopy did not show polyamide molecular alteration. The indirect cytotoxicity test revealed that the imported polyamide is cytotoxic to the cell line tested and, therefore, its use is not recommended in vivo, despite the favorable mechanical test results. Thus, the national steam-sterilized nylon fishing line is a viable alternative for the CCLI treatment, has low cost, easy acquisition, and can be used in other types of articular surgeries and in veterinary fields that require a more resistant suture.

17.
Rev. chil. neuropsicol. (En línea) ; 15(1): 12-17, oct. 2020. graf
Artigo em Espanhol | LILACS | ID: biblio-1353767

RESUMO

La rehabilitación neuropsicológica es una terapia que busca mejorar la independencia y autonomía en pacientes que presentan dificultades cognitivas. El objetivo de la investigación fue determinar la eficacia de un programa de rehabilitación neuropsicológica en una paciente con diagnóstico de trastorno neurocognitivo leve, tipo ejecutivo, asociado a trastorno límite de la personalidad, mediante el fortalecimiento de la atención y de los procesos ejecutivos implicados en la memoria, bajo los principios de sustitución y restitución. Los instrumentos para establecer línea base y para medir el efecto del tratamiento fueron la escala de trastornos de la memoria y la escala de criterios del trastorno límite de la personalidad (TLP) basados en el DSM-V; estos instrumentos se le aplicaron a la paciente y también a su informador para comparar los datos. Los resultados arrojaron una mejoría estadística en las puntuaciones de la escala de trastornos de la memoria y de la escala de criterios para el TLP-DSM-V; pasando de tener una puntuación en memoria de 36 en línea base a 16 después de la intervención, también pasó de tener 3 criterios para impulsividad a 1 criterio después de la intervención. Finalmente se establece la eficacia de la rehabilitación neuropsicológica en los pacientes con TLP, no solo se evidencia mejoría en los síntomas cognitivos asociados a las dificultades en la memoria, sino que también se muestra disminución en los síntomas psiquiátricos asociados con el control de los impulsos.


Neuropsychological rehabilitation is a therapy that seeks to improve independence and autonomy in patients with cognitive difficulties. The objective of the investigation was to determine the efficacy of a neuropsychological rehabilitation program in a patient diagnosed with a mild neurocognitive disorder, executive type, associated with borderline disorder personality, by strengthening attention and executive processes involved in memory, under the principles of substitution and restitution. The instruments to establish a baseline and to measure the effect of treatment were the memory disorders scale and the DSM-V-based borderline personality disorder (BPD) criteria scale; these instruments were applied to the patient and also to her informant to compare the data. The results showed a statistical improvement in the scores of the memory disorders scale and the criteria scale for the BPD-DSM-V; going from having a memory score of 36 at baseline to 16 after the intervention, it also went from having three criteria for impulsivity to one criterion after the intervention. Finally, the efficacy of neuropsychological rehabilitation in patients with BPD is established, not only is there an improvement in the cognitive symptoms associated with memory difficulties, but also a decrease in the psychiatric symptoms associated with impulse control.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Transtorno da Personalidade Borderline/reabilitação , Disfunção Cognitiva/reabilitação , Transtorno da Personalidade Borderline/fisiopatologia , Resultado do Tratamento , Disfunção Cognitiva/fisiopatologia , Comportamento Impulsivo/fisiologia , Neuropsicologia/métodos
18.
Infant Ment Health J ; 41(6): 793-810, 2020 11.
Artigo em Inglês | MEDLINE | ID: mdl-32602964

RESUMO

Despite the longstanding theoretical association in the attachment literature between maternal trauma history and disturbances in the mother-infant interaction, few studies have investigated mechanisms of transmission of traumatogenic relational patterns in high-risk mother-infant dyads. This study investigated interrelationships among maternal trauma history, distorted maternal representations (DMRs, i.e. disturbed thoughts and feelings about the infant and self-as-parent), maternal mentalisation (i.e. capacity to conceive of self and other's intentions in terms of mental states including thoughts, feelings, and desires), and quality of interaction in a clinical sample of mothers with Borderline Personality Disorder (BPD) features and their infants (N = 61). Measures used included the Childhood Trauma Questionnaire, Parent Development Interview, Mother-Infant Relationship Scale, Borderline Symptom Checklist-23, and the Emotional Availability Scales. The results indicated BPD features mediated the relationship between maternal trauma history and DMRs predicting disturbance in interaction. In addition, analyses showed that maternal mentalisation had a buffering effect between DMRs and maternal non-hostility and yet the severity of BPD features moderated the relationship between mentalisation and DMRs. The findings suggest postpartum borderline pathology may adversely impact the experience of being a parent for women with a relational trauma history including deficits in mentalisation (i.e. hypermentalising) and disturbances in the mother-infant interaction. Implications for research and clinical practice are discussed.


A pesar de la larga asociación teorética en la literatura de la afectividad entre el historial de trauma materno y perturbaciones en la interacción madre-infante, pocos estudios han investigado mecanismos de transmisión de patrones de relación traumatogénicos en díadas madre-infante de alto riesgo. Este estudio investigó interrelaciones entre el historial de trauma materno, las distorsionadas representaciones maternas (DMR, v.g. pensamientos y sentimientos perturbados acerca del infante y de sí misma como madre), la mentalización materna (v.g. capacidad para concebir las intenciones propias y de otros en términos de estados mentales), y la calidad de interacción en un grupo muestra clínico de madres con características de Trastornos de Personalidad Limítrofe (BPD) y sus infantes (N = 61). Entre las medidas usadas están el Cuestionario de Trauma de Niñez, la Entrevista de Desarrollo de la Progenitora, la Escala de Relación Madre-Infante, la Lista de Verificación de Síntomas de Personalidad Limítrofe - 23, y las Escalas de Disponibilidad Emocional. Los resultados indicaron que las características BPD mediaron la relación entre el historial de trauma materno y las DMR prediciendo perturbaciones en la interacción. Es más, los análisis mostraron que la mentalización materna tenía un efecto amortiguador entre las DMR y la no hostilidad materna y aun así la severidad de las características BPD moderaron la relación entre la mentalización y las DMR. Los resultados sugieren que la patología limítrofe posterior al parto pudiera impactar adversamente la experiencia de ser madre para mujeres con historial de trauma, incluyendo déficits en la mentalización (v.g. la hipermentalización) y las perturbaciones en la interacción madre-infante. Se discuten las implicaciones para la investigación y la práctica clínica.


En dépit de la longue association théorique dans les recherches sur l'attachement entre le passé de trauma de la mère et les perturbations dans l'interaction mère-bébé, il existe peu d'études portant sur les mécanismes de transmission de patterns relationnels traumagénétiques chez les dyades mère-bébé à haut risque. Cette étude s'est penchée sur les interrelations entre le passé de trauma de la mère, des représentations maternelles déformées (des DMR, c'est-à-dire des pensées déformées ainsi que des sentiments déformés sur le bébé et soi-même en tant que parent), la mentalisation maternelle (c'est-à-dire la capacité de concevoir ses propres intentions ainsi que celles des autres en termes d'états mentaux), et la qualité de l'interaction chez un échantillon clinique de mères ayant les caractéristiques du trouble de la personnalité limite et leurs bébé (N = 61). Les mesures utilisées ont inclus le Questionnaire de Trauma de l'Enfance, l'Entretien du Développement du Parent, l'Echelle de Relation Mère-Bébé, la Checklist de Symptômes de la Personnalité Limite-23, ainsi que les Echelles de Disponibilité Emotionnelle. Les résultats ont indiqué que les traits de TPL affectaient la relation entre l'histoire de trauma de la mère et les DMS = R prédisant une perturbation dans l'interaction. De plus les analyses ont montré que la mentalisation maternelle faisait effet de tampon entre les DMR et la non-hostilité maternelle et pourtant la sévérité des traits TPL modérait la relation entre la mentalisation et les DMR. Les résultats suggèrent qu'une pathologie limite postpartum pourrait avoir un impact adverse sur l'expérience de parentage pour les femmes ayant un passé de trauma, y compris des déficits dans la mentalisation (par exemple, une hyper-mentalisation) et des perturbations dans l'interaction mère-bébé. Les implications pour les recherches et la pratique clinique sont discutées.


Assuntos
Transtorno da Personalidade Borderline/psicologia , Emoções , Relações Mãe-Filho/psicologia , Mães/psicologia , Adulto , Feminino , Humanos , Lactente , Pais/psicologia , Período Pós-Parto/psicologia , Inquéritos e Questionários
19.
Encephale ; 46(6): 463-470, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32571544

RESUMO

Building on existing literature, the authors draw the landscape of psychiatric emergencies, and focus on borderline personality disorder, frequently encountered, and strongly linked to death by suicide. A review of knowledge in terms of diagnosis, prognosis, etiology, and treatment, as well as their own experiences, lead them to propose areas of progress that would secure the patient's care pathway. The evolution of society has led psychiatric emergency departments to play the role of a safety net and an entry point to the mental health system. Borderline personality disorder is one of the most common pathologies encountered in psychiatric emergencies. It represents a major concern, long characterized by an often dramatic evolution, and by the human and economic stress it generates. However, since the 1990s, knowledge of this disorder has been refined, and today there are various means of evaluation, good clinical practices and psychotherapeutic treatments, thanks to which significant and lasting improvement is possible. Recent studies highlight the crucial role of hospital caregivers, and the benefit of consolidating their skills by providing them with the knowledge and tools specific to this disorder. They also converge on the interest of setting up specific emergency treatment modalities, particularly highly structured, safe and empowering for the patient, in order to improve their effectiveness. The authors suggest that a case formulation model for persons with borderline personality disorder in emergency would make it possible to activate these two levers of progress, while improving collaboration between hospital and outpatient care. This would also address their main concern of optimizing the patient's therapeutic pathway and reinforcing adherence to treatment that could bring remission, and should be supported by data from empirical research.


Assuntos
Transtorno da Personalidade Borderline , Transtorno da Personalidade Borderline/terapia , Humanos
20.
J Anal Psychol ; 65(3): 584-599, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32406944

RESUMO

This paper explores the inevitable pain that integration requires in our individuation process. The unspeakable agony we defended against in order to survive we now experience consciously, including moments of going out of existence at the core of our madness. Clinical examples are given of these 'extinction points' and the abject helplessness analysand and analyst suffer in the face of this destructiveness. The first and second witness to this process (usually the analyst and the psyche itself) and the primordial creative life force are recognized in the process of recovery, a recovery that recoups the blessings of our finite human living.


Cet article explore la souffrance inévitable que requiert l'intégration dans le processus d'individuation. L'indicible tourmente contre laquelle nous nous défendions afin de survivre est ce dont nous faisons maintenant l'expérience de manière consciente, y compris dans les moments de sortie de l'existence, au noyau de notre folie. Des exemples cliniques de ces « points d'extinction ¼ sont donnés, ainsi que de la détresse extrême vécue par l'analysant et l'analyste devant cette destructivité. Le premier et le second témoin de ce processus (généralement l'analyste et la psyché elle-même) ainsi que la force de vie créative et primaire sont reconnus dans le processus de rétablissement, un rétablissement qui opère le recouvrement des bénédictions de notre vie humaine limitée.


El presente trabajo explora el dolor inevitable que requiere la integración en nuestro proceso de individuación. La agonía indescriptible de la cual nos defendemos para sobrevivir, ahora la experimentamos de manera consciente, incluyendo aquellos momentos por fuera de la existencia al centro de nuestra locura. Se ofrecen ejemplos clínicos de estos 'puntos de extinción' y la abyecta impotencia que analista y analizando sufren ante esta destructividad. El primero y el segundo testigo de este proceso (usualmente el analista y la psique misma) y la fuerza vital creativa primordial son reconocidas/os en el proceso de recuperación, una recuperación que recobra las bendiciones de nuestra finitud humana.


Assuntos
Individuação , Transtornos Mentais/psicologia , Humanos , Teoria Junguiana
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