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1.
Braz. j. biol ; 84: e260771, 2024. tab, graf
Artigo em Inglês | VETINDEX | ID: biblio-1384111

RESUMO

This research was aimed to study the lipid fraction of date seeds. Seventeen seeds of date palm varieties and clones were evaluated and assessed for their chemical components and for the properties of the date pits oil. Gas liquid chromatography showed that the main unsaturated fatty acid was oleic acid (46.00 - 50.87%), while the main saturated fatty acid was lauric acid (10.11 - 19.03%) for the cultivars Mentouj Tissgharine (MTN) and Bheir Ingli (KBN) respectively; other fatty acids were also identified. The physicochemical characterization showed an acid value ranging from 0.068 to 1.188%, a specific extinction value equal to (K232: 1.350-2.225; K270: 0.318- 0.521), a peroxide value in the interval (1.059-5.618 meq O2/kg) and an iodine value (41.861-59.980 g Iodine/100 g). The pheophytin content of date seed oils was found within the range from 21.855 to 75.685%. The chemical analysis showed that date seed oil can be useful in cosmetic and food products processing.


Dezessete sementes de variedades e clones de tamareiras foram avaliadas quanto aos seus componentes químicos e às propriedades do óleo de caroço de tâmara. A cromatografia gasosa líquida mostrou que o principal ácido graxo insaturado foi o ácido oleico (46,00% - 50,87%), enquanto o principal ácido graxo saturado foi o ácido láurico (10,11% - 19,03%) para as cultivares MTN e KBN, respectivamente; outros ácidos graxos também foram identificados. A caracterização físico-química mostrou um valor ácido variando de 0,068% a 1,188%, um valor específico de extinção igual a (K232: 1,350-2,225; K270: 0,318-0,521), um valor de peróxido no intervalo (1,059-5,618 meq O2/kg) e um valor de iodo (41,861-59,980 g Iodo/100 g). O teor de feofitina dos óleos de sementes de tâmara foi encontrado na faixa de 21,855% a 75,685%. A análise química mostrou que o óleo de semente de tâmara pode ser útil no processamento de produtos cosméticos e alimentícios.


Assuntos
Sementes , Cromatografia Gasosa , Ácido Oleico , Ácidos Graxos , Phoeniceae
2.
Braz. j. biol ; 84: e252426, 2024. tab, ilus
Artigo em Inglês | VETINDEX | ID: biblio-1374656

RESUMO

Fresh dates of seventeen varieties and khalts from Southern Morocco were analysed for their colour, pigments content, and sensory profile. The results showed significant differences between the sensory profiles of the samples due to the variability of the genotype and their different origin. Fresh date varieties and khalts were a good source of ß-carotene (0.49 - 10.86 µg of ß-carotene /100 g FW). The results revealed that the date varieties and khalts were found to have an excellent functional composition and good sensory characteristics. Therefore, these varieties of Moroccan dates could be used for fresh consumption and in the processing industry, which will constitute a significant source of antioxidants.


Tâmaras frescas de 17 variedades e khalts do sul do Marrocos foram analisadas por sua cor, conteúdo de pigmentos e perfil sensorial. Os resultados mostraram diferenças significativas entre os perfis sensoriais das amostras devido à variabilidade do genótipo e suas diferentes origens. Variedades de tâmaras frescas e khalts foram consideradas uma boa fonte de ß-caroteno (0,49-10,86 µg de ß-caroteno / 100 g FW). Na verdade, os resultados revelaram que as variedades de tâmaras e khalts apresentam uma boa composição funcional e boas características sensoriais. Portanto, essas variedades de tâmaras marroquinas podem ser usadas para consumo in natura e na indústria de processamento, que constituirá uma fonte considerável de antioxidantes.


Assuntos
Pigmentação da Pele , Carotenoides , Phoeniceae/genética , Antioxidantes
3.
Biotechnol Lett ; 2022 Sep 13.
Artigo em Inglês | MEDLINE | ID: mdl-36100779

RESUMO

OBJECTIVES: The present study aimed to explore the eliciting effects of increasing concentrations (50, 100, and 200 µM) of methyl jasmonate (MeJA). We cultivated actively proliferating buds of Phoenix dactylifera L. cv. Barhee in a temporary immersion system and we monitored the bioactive compound accumulation after 7 days of culture. METHODS: Total phenolic (TPC) and flavonoid (TFC) contents were determined by high-performance liquid chromatography (HPLC), Fourier-transform infrared (FTIR), and radical scavenging activity using DPPH and ABTS assays. We also explored the activity of phenylpropanoid pathway enzymes, namely phenylalanine ammonia-lyase (PAL), tyrosine ammonia-lyase (TAL) and polyphenol oxidase (PPO). RESULTS: Our results revealed that MeJA treatment induced oxidative stress, and at the same time increased the activity of related defense enzymes in a dose-dependent manner. Exogenous application of MeJA at 200 µM increased ROS (two fold), hydrogen peroxide (3.7 fold), nitric oxide (14 fold), MDA (6.3 fold), superoxide dismutase (5.9 fold), catalase (4.4 fold) and guaiacol peroxidase (3.87 fold). Furthermore, the results demonstrated that 200 µM MeJA treatment enhanced the activities of PAL (3.65 fold), TAL (4.35 fold), PPO (threefold) and increased TPC (twofold) and TFC (1.75 fold) contents in buds cultures higher than the control. HPLC analysis showed that buds cultures exposed to 200 µM MeJA accumulated maximum amount of catechin (11 fold), 4-hydroxybenzoic acid (1.48 fold), caffeic acid (2.5 fold) and p-coumaric acid (1.76 fold) and demonstrate antioxidant capacity with the lowest DPPH (114.5 µg ml-1) and ABTS (90.2 µg ml-1) IC50 values on day 7 of culture as compared to the control. The MeJA in the culture medium directly reduced cell viability in a dose dependent manner up to 35% with the highest concentration. CONCLUSION: The results of this study has revealed, for the first time, that MeJA offers a promising potential for the production of phenolic compound in Phoenix dactylifera L. buds.

4.
Foods ; 11(17)2022 Aug 30.
Artigo em Inglês | MEDLINE | ID: mdl-36076815

RESUMO

Date palm (Phoenix dactylifera L.) is one of the world's oldest cultivated plants. Post-harvest losses of date palm due to fungal contamination reached up to 50% of the total production. This study aimed to investigate the potential of the extract of Tasmanian pepper leaf (TPL) and the non-thermal treatment of photosensitization mediated by curcumin in reducing the fungal contamination and enhancing the shelf life of date palm. In the in vivo storage study, the dates were treated with three different concentrations of TPL extract 12.5, 25, and 50 µg/mL and stored at 30 °C. The findings obtained for the treatment with TPL extract exhibited potent antifungal activity against most of the tested fungi, where minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) were < 25 µg/mL for polygodial, the bioactive compound in TPL. The shelf life of date palm treated by 50 µg/mL polygodial was extended up to 21 days, thrice as much as the untreated controls. In contrast, a lower concentration of TPL extract (25 µg/mL polygodial) revealed up to a 15-day shelf life extension compared to untreated dates (7 days). The results obtained from the study suggested that using TPL extracts against pathogenic and spoilage fungi occurring in fresh date fruits is a promising treatment for the shelf life extension of fresh date fruits at room temperature.

5.
Molecules ; 27(16)2022 Aug 13.
Artigo em Inglês | MEDLINE | ID: mdl-36014407

RESUMO

The pharmaceutical research sector's inability to produce new drugs has made it difficult to keep up with the rate at which microbial resistance is developing. Recently, nanotechnology and its combinations with natural products have been the saviors against multidrug resistant bacteria. In the present investigation, different Egyptian and Saudi date cultivars were extracted and then phytochemically analyzed and tested for possible antimicrobial activities against multidrug resistant (MDR) microbes. The results revealed that extract of the flesh of fresh "Hayany" fruit (Egyptian date) showed the highest antimicrobial activity, with high levels of phenolic, flavonoid, and tannin concentrations (538.578 µg/mL, 28.481 µg/mL, and 20.888 µg/mL, respectively) and high scavenging activity, with an IC50 reaching 10.16 µg/mL. The highest synergistic activity was found between fresh "Hayany" fruit extract and amikacin. Novel nano-fresh fruit of "Hayany" date extract was synthesized using a ball-milling technique. The vesicle size was 21.6 nm, while the PDI and zeta potential were 0.32 and +38.4 mV, respectively. The inhibition zone diameters of nano-fresh fruit of "Hayany" date extract/amikacin reached 38 mm and 34 mm, with complete microbial eradication after 9 h and 6 h, against Candida albicans and Staphylococcus aureus, respectively. In conclusion, date fruit extract could be used as a candidate bioactive compound in the fight against infectious diseases.


Assuntos
Anti-Infecciosos , Nanopartículas , Phoeniceae , Amicacina , Antibacterianos/química , Anti-Infecciosos/análise , Anti-Infecciosos/farmacologia , Antioxidantes/química , Frutas/química , Phoeniceae/química , Extratos Vegetais/química
6.
Curr Drug Metab ; 2022 Aug 20.
Artigo em Inglês | MEDLINE | ID: mdl-35993475

RESUMO

AIMS: This study aimed to investigate the effects of consuming Phoenix dactylifera and fasting on the mRNA expression of major hepatic drug-metabolizing enzymes in mice. METHODS: Phoenix dactylifera ethanolic extract was analyzed using LC-MS/MS. We used forty-two male Balb/c mice which were treated with low (300 mg/kg) and high (2583 mg/kg) doses of Phoenix dactylifera and fasted for 24 hours, two weeks, and one month. Then, we analyzed the expression of cyp3a11, cyp2c29, cyp2d9, and ugt2b1 using real-time polymerase chain reaction assay. In addition, we assessed the relative liver weights of the mice and the hepatic phathohistological alterations. RESULTS: We found that Phoenix dactylifera ethanolic extract contained 38 phytochemical compounds mainly kaempherol, campesterol, lutein, apigenin, genistein, and isoquercetin. Fasting significantly upregulated the mRNA expression of several drug-metabolizing enzymes in a time-dependent manner and we showed that consuming the low dose of Phoenix dactylifera significantly upregulated the expression of drug-metabolizing enzymes more than the high dose. The results of the histological examinations and relative liver weight showed that fasting and consuming of Phoenix dactylifera did not cause any toxicological alterations in the liver of the mice. CONCLUSION: It is concluded from this study that fasting and consuming of Phoenix dactylifera upregulated the mRNA expression of major drug-metabolizing enzymes in mouse livers. These findings may explain, at least partly, the variation of drug response during fasting of the month of Ramadan and would direct future clinical studies in optimizing dosing of pharmacotherapeutic regimen.

7.
J Biotechnol ; 357: 47-55, 2022 Sep 20.
Artigo em Inglês | MEDLINE | ID: mdl-35963593

RESUMO

The red palm weevil (RPW), Rhynchophorus ferrugineus, is considered a severe pest of palms. Usually, the early stages of infection are without visible signs. An attractive early sensing approach of non-visible infections is based on volatile organic compounds (VOCs). In this study, a whole-cell bacterial biosensor was used for the identification of RPW in date palm (Phoenix dactylifera). The cells are genetically modified to produce light in the presence of general stresses. The bioluminescent bacterial panel is based on three genetically engineered Escherichia coli strains that are sensitive to cytotoxicity (TV1061), genotoxicity (DPD2794), or quorum-sensing (K802NR). The bioluminescent bacterial panel detects the presence of VOCs and a change in the light signal is then generated, reflecting the health status of the date palm tree. The bioreporter bacteria cells are immobilized in calcium alginate tablets and placed in a sealed jar without direct contact with the tested sample, thereby exposing them only to the VOCs in the surrounding air. The immobilized bacteria cells were exposed to the air near infected by RPW or uninfected sugar canes, date palm tree pieces, and on date palm trees. Commercial plate reader was used for signal measurement. The findings show that quorum-sensing was induced by all the tested samples of infected sugar canes, date palm tree pieces, and date palm trees. While, cytotoxicity was induced only by infected date palm tree pieces, and genotoxicity was induced only by infected date palm trees. The bacterial monitoring results enable the identification of specific signatures that will allow a quick and accurate diagnosis.


Assuntos
Técnicas Biossensoriais , Phoeniceae , Compostos Orgânicos Voláteis , Gorgulhos , Animais , Bactérias , Estudo de Prova de Conceito , Açúcares , Gorgulhos/microbiologia
8.
Plants (Basel) ; 11(15)2022 Aug 03.
Artigo em Inglês | MEDLINE | ID: mdl-35956500

RESUMO

Many embryogenic systems have been designed to generate somatic embryos (SEs) with the morphology, biochemistry, and vigor uniformity of zygotic embryos (ZEs). During the current investigation, several antioxidants were added to the maturation media of the developing somatic embryos of date palm. Explant material was a friable embryogenic callus that was placed in maturation media containing ABA at 0.5 mg L-1, 5 g L-1 polyethylene glycol, and 10 g L-1 phytagel. Furthermore, α-tocopherol or reduced glutathione (GSH) were used separately at (25 and 50 mg L-1). These treatments were compared to a widely used date palm combination of reduced ascorbic acid (ASC) and citric acid at 150 and 100 mg L-1, respectively, and to the medium free from any antioxidants. The relative growth percentage of embryogenic callus (EC), globularization degree, differentiation%, and SEs number were significantly increased with GSH (50 mg L-1). Additionally, the latter treatment significantly enhanced the conversion% of SEs and the number of secondary somatic embryos (SSEs). ASC and citric acid treatment increased leaf length, while α-tochopherol (50 mg L-1) elevated the number of leaves plantlet-1. GSH at 50 mg L-1 catalyzed the activities of polyphenol oxidase (PPO) and peroxidase (POD) in EC and enhanced the accumulation of proteins in SEs.

9.
Front Neurosci ; 16: 915122, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35958986

RESUMO

Alzheimer's disease (AD) is a neurodegenerative disease and the most prevalent form of dementia. The generation of oxygen free radicals and oxidative damage is believed to be involved in the pathogenesis of AD. It has been suggested that date palm, a plant rich in phenolic compounds and flavonoids, can provide an alternative treatment to fight memory loss and cognitive dysfunction due to its potent antioxidant activity. Thus, we studied the effect of flavonoids present in date palm on Aß1-40 amyloid formation using molecular docking and molecular dynamics simulation. AutoDock. Myricetin was used as a positive control drug. The flavonoids Diosmetin, Luteolin, and Rutin were found to be potent inhibitors of aggregation (docking energies ≤ -8.05 kcal mol-1) targeting Aß1-40 fibrils (both 2LMO and 6TI5), simultaneously. Further screening by physicochemical properties and drug-likeness analysis suggested that all flavonoids except Rutin followed Lipinski's rule of five. Rutin was, thus, taken as a negative control (due to its violation of Lipinski's rule) to compare its dynamics with Diosmetin. Diosmetin exhibited the highest positive scores for drug likeness. Since Luteolin exhibited moderate drug-likeness and better absorption properties, it was also included in molecular dynamics simulation. Molecular dynamics of shortlisted compounds (Rutin, Diosmetin, and Luteolin) were performed for 200 ns, and the results were analyzed by monitoring root mean square deviations (RMSD), root mean square fluctuation (RMSF) analysis, the radius of gyration (Rg), and solvent accessible surface area (SASA). The results proved the formation of a stable protein-compound complex. Based on binding energies and non-bonded interactions, Rutin and Luteolin emerged as better lead molecules than Diosmetin. However, high MW (610.5), lowest absorption rate (16.04%), and more than one violation of Lipinski's rule make Rutin a less likely candidate as an anti-amyloidogenic agent. Moreover, among non-violators of Lipinski's rule, Diosmetin exhibited a greater absorption rate than Luteolin as well as the highest positive scores for drug-likeness. Thus, we can conclude that Diosmetin and Luteolin may serve as a scaffold for the design of better inhibitors with higher affinities toward the target proteins. However, these results warrant in-vitro and in-vivo validation before practical use.

10.
Nanomaterials (Basel) ; 12(14)2022 Jul 17.
Artigo em Inglês | MEDLINE | ID: mdl-35889673

RESUMO

Iron oxide nanoparticles (FexOy-NPs) are currently being applied in numerous high-tech sectors, such as in chemical sectors for catalysis and in the medical sector for drug delivery systems and antimicrobial purposes, due to their specific, unique and magnetic properties. Nevertheless, their synthesis is under continuous investigation, as physicochemical methods are considered expensive and require toxic solvents. Thus, green nanotechnology has shown considerable promise in the eco-biogenesis of nanoparticles. In the current study, FexOy-NPs were synthesized by two different methods: via green synthesis through the use of polyphenols, which were extracted from Phoenix dactylifera L.; and via chemical synthesis, in which the reducing agent was a chemical (NaOH), and iron chloride was used as a precursor. Thus, polyphenol extraction and its ability to produce nanoparticles were evaluated based on the drying temperature used during the Phoenix dactylifera L. recollection, as well as the extraction solvent used. The results highlight the potential of polyphenols present in Phoenix dactylifera L. for the sustainable manufacture of FexOy-NPs. Finally, green and chemical syntheses were compared on the basis of physicochemical characteristics and functional properties.

11.
Front Plant Sci ; 13: 874858, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35783933

RESUMO

Global food security is a critical concern that needs practical solutions to feed the expanding human population. A promising approach is the employment of biostimulants to increase crop production. Biostimulants include compounds that boost plant growth. Recently, mimics of zaxinone (MiZax) were shown to have a promising growth-promoting effect in rice (Oryza sativa). In this study, we investigated the effect of MiZax on the growth and yield of three dicot horticultural plants, namely, tomato (Solanum lycopersicum), capsicum (Capsicum annuum), and squash (Cucurbita pepo) in different growth environments, as well as on the growth and development of the monocot date palm (Phoenix dactylifera), an important crop in the Middle East. The application of MiZax significantly enhanced plant height, flower, and branch numbers, fruit size, and total fruit yield in independent field trials from 2020 to 2021. Importantly, the amount of applied MiZax was far less than that used with the commercial compound humic acid, a widely used biostimulant in horticulture. Our results indicate that MiZax have significant application potential to improve the performance and productivity of horticultural crops.

12.
Antioxidants (Basel) ; 11(6)2022 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-35739959

RESUMO

The current study aimed to understand the synergistic impacts of silicon (Si; 1.0 mM) and boron (B; 10 µM) application on modulating physio-molecular responses of date palm to mitigate aluminum (Al3+; 2.0 mM) toxicity. Results revealed that compared to sole Si and B treatments, a combined application significantly improved plant growth, biomass, and photosynthetic pigments during Al toxicity. Interestingly, Si and B resulted in significantly higher exudation of organic acid (malic acids, citric acids, and acetic acid) in the plant's rhizosphere. This is also correlated with the reduced accumulation and translocation of Al in roots (60%) and shoots (56%) in Si and B treatments during Al toxicity compared to in sole Al3+ treatment. The activation of organic acids by combined Si + B application has significantly regulated the ALMT1, ALMT2 and plasma membrane ATPase; PMMA1 and PMMA3 in roots and shoots. Further, the Si-related transporter Lsi2 gene was upregulated by Si + B application under Al toxicity. This was also validated by the higher uptake and translocation of Si in plants. Al-induced oxidative stress was significantly counteracted by exhibiting lower malondialdehyde and superoxide production in Si + B treatments. Experiencing less oxidative stress was evident from upregulation of CAT and Cyt-Cu/Zn SOD expression; hence, enzymatic activities such as polyphenol oxidase, catalase, peroxidase, and ascorbate peroxidase were significantly activated. In the case of endogenous phytohormones, Si + B application demonstrated the downregulation of the abscisic acid (ABA; NCED1 and NCED6) and salicylic acid (SA; PYL4, PYR1) biosynthesis-related genes. Consequently, we also noticed a lower accumulation of ABA and rising SA levels under Al-stress. The current findings illustrate that the synergistic Si + B application could be an effective strategy for date palm growth and productivity against Al stress and could be further extended in field trails in Al-contaminated fields.

13.
Foods ; 11(12)2022 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-35742004

RESUMO

Date (Phoenix dactylifera) seed is a potential source of natural antioxidants, and the use of innovative green and low temperature antioxidant recovery techniques (using CO2 as solvent) such as supercritical fluid (SFE) and subcritical (SubCO2) extractions can improve their yields and quality in the extracts. SFE, SubCO2 and Soxhlet techniques were employed to enrich antioxidants in extracts from Sukari (SKSE), Ambara (AMSE), Majdool (MJSE) and Sagai (SGSE) date seeds. Extract yields were evaluated and modelled for SFE extract using response surface methodology. Significantly higher (p < 0.05) phenolics (143.48-274.98 mg GAE/100 g), flavonoids (78.35-141.78 mg QE/100 g), anthocyanins (0.39-1.00 mg/100 g), and carotenoid (1.42-1.91 mg BCE/100 g) contents were detected in extracts obtained using SFE and SubCO2 methods. The evaluation of in vitro antioxidant properties showed that SFE and SubCO2 seed extracts demonstrated promising antioxidant (13.42-23.83 µg AAE/mL), antiradical (228.76-109.69 µg/mL DPPH IC50), ferric reducing antioxidant power (1.43-2.10 mmol TE/100 g) and ABTS cation scavenging (375.74-717.45 µmol TE/100 g) properties that were significantly higher than Soxhlet extracts. Both SFE and SubCO2 techniques can be effectively utilized as innovative and environmentally friendly alternatives to obtain high quality antioxidant rich extracts from date seed. These extracts may have potential functional and nutraceutical applications.

14.
Foods ; 11(11)2022 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-35681335

RESUMO

Edible chitosan coatings with natural functional ingredients were used to preserve quality attributes of fresh Barhi date fruit. Fruits were coated with chitosan and/or 1 and 2% olive cake extract (OCE) or orange peel extract (OPE). Both coated and uncoated fruits were stored at 4 °C for 4 weeks. A slight decrease in the pH and increase in acidity with storage was observed. However, when chitosan was mixed with OCE or OPE, an increase in pH was observed with a concomitant decrease in acidity. The phenolic content of the samples was decreased with time. However, coating the date with OCE or OPE significantly (p ≤ 0.05) increased the total phenolic with a concomitant increase in radical scavenging activity. The textural properties, particularly hardness, were better preserved in case of coated dates. The sensory evaluation data showed non-significant changes in the acceptability of the Barhi dates throughout the storage period. Chitosan-coating significantly (p ≤ 0.05) inhibited mold growth over time. Scanning electron microscope (SEM) imaging showed difference among different coatings. According to principal component analysis (PCA), OCE and OPE were found to have protective effects on fruit quality.

15.
Arch Microbiol ; 204(7): 436, 2022 Jun 28.
Artigo em Inglês | MEDLINE | ID: mdl-35763072

RESUMO

In recent decades, the prevalence of hyperuricemia has increased, and dietary fructose is an important risk factor for the development of this disease. This study investigated and compared the effects of Sphacelotheca reiliana polysaccharides and Phoenix dactylifera monosaccharides on a series of physiological and biochemical indicators and on the metagenomes and serum metabolites in mice with hyperuricemia caused by a high-fructose diet. S. reiliana polysaccharides inhibited uric acid biosynthesis and promoted uric acid excretion, thereby alleviating the hyperuricemia phenotype. In addition, hyperuricemia was closely related to the gut microbiota. After treatment with S. reiliana polysaccharides, the abundances of Bacteroidetes and Proteobacteria in the mouse intestines were decreased, the expression of genes involved in glycolysis/gluconeogenesis metabolic pathways and purine metabolism was downregulated, and the dysfunction of the gut microbiota was alleviated. With regard to serum metabolism, the abundance of hippuric acid, uridine, kynurenic acid, propionic acid and arachidonoyl decreased, and the abundances of serum metabolites in inflammatory pathways involved in kidney injury and gout, such as bile acid metabolism, purine metabolism and tryptophan metabolism pathways, decreased. P. dactylifera monosaccharides aggravated hyperuricemia. This research provides a valuable reference for the development of sugar applications.


Assuntos
Microbioma Gastrointestinal , Hiperuricemia , Phoeniceae , Animais , Frutose/efeitos adversos , Hiperuricemia/induzido quimicamente , Hiperuricemia/tratamento farmacológico , Camundongos , Monossacarídeos , Polissacarídeos , Ácido Úrico
16.
Appl Biochem Biotechnol ; 194(10): 4587-4624, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35579740

RESUMO

A novel coronavirus disease (COVID-19) or severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), transmitted from person to person, has quickly emerged as the pandemic responsible for the current global health crisis. This infection has been declared a global pandemic, resulting in a concerning number of deaths as well as complications post-infection, primarily among vulnerable groups particularly older people and those with multiple comorbidities. In this article, we review the most recent research on the role of date palm (Phoenix dactylifera L.) fruits (DPFs) to prevent or treat COVID-19 infection. The mechanisms underlying this preventive or therapeutic effect are also discussed in terms of bioactivity potentials in date palm, e.g., antimicrobial, antioxidant, anticancer, anti-diabetic, anti-inflammatory, neuroprotective, and hemolytic potential, as well as prospect against COVID-19 disease and the potential product development. Therefore, it can be concluded that regular consumption of DPFs may be associated with a lower risk of some chronic diseases. Indeed, DPFs have been widely used in folk medicine since ancient times to treat a variety of health conditions, demonstrating the importance of DPFs as a nutraceutical and source of functional nourishment. This comprehensive review aims to summarize the majority of the research on DPFs in terms of nutrient content and biologically active components such as phenolic compounds, with an emphasis on their roles in improving overall health as well as the potential product development to ensure consumers' satisfaction in a current pandemic situation. In conclusion, DPFs can be given to COVID-19 patients as a safe and effective add-on medication or supplement in addition to routine treatments.


Assuntos
Anti-Infecciosos , COVID-19 , Phoeniceae , Idoso , Antioxidantes/farmacologia , Antioxidantes/uso terapêutico , COVID-19/tratamento farmacológico , Humanos , Pandemias , SARS-CoV-2
17.
Saudi J Biol Sci ; 29(4): 2564-2572, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-35531215

RESUMO

Availability of efficient male genotypes is critical for successful artificial pollination and regular bearing of female date palms. The effect of flowering stage and storage conditions on pollen quality of six male date palm genotypes encoded 'ABD1', 'P4', 'P3', 'P8', 'P7' and 'P13'were evaluated. Pollen collected from spathes developed at the middle of flowering stage exhibited the best viability (90%) and germinability (85%) compared to other stages. Pollen viability was greater than 90%, except for 'P8' that exhibited 80%, while, germinability greatly varied among the genotypes. Pollen quality decreased during 4 months of storage upon genotype and temperature, with a minimum reduction at -30 °C followed by 4 °C. Heat shock exposure (33 ± 2 °C) following storage revealed that pollen stored at -30 °C or 4 °C should be used for pollination on the same day of take out to avoid dramatic quality loss. The 'ABD1', an early flowering genotype, proved highest pollen quality both at fresh stage and after storage. While, the 'P3', a late flowering genotype, retained its pollen quality during storage. However, the 'P13' genotype exhibited excellent pollen quality when fresh, but greatly loses germinability during storage.

18.
Molecules ; 27(10)2022 May 12.
Artigo em Inglês | MEDLINE | ID: mdl-35630588

RESUMO

The Arabian desert is rich in different species of medicinal plants, which approved variable antimicrobial activities. Phoenix dactylifera L. is one of the medical trees rich in phenolic acids and flavonoids. The current study aimed to assess the antibacterial and antifungal properties of the silver nanoparticles (AgNPs) green-synthesized by two preparations (ethanolic and water extracts) from palm leaves. The characteristics of the produced AgNPs were tested by UV-visible spectroscopy and Transmitted Electron Microscopy (TEM). The antifungal activity of Phoenix dactylifera L. was tested against different species of Candida. Moreover, its antibacterial activity was evaluated against two Gram-positive and two Gram-negative strains. The results showed that AgNPs had a spherical larger shape than the crude extracts. AgNPs, from both preparations, had significant antimicrobial effects. The water extract had slightly higher antimicrobial activity than the ethanolic extract, as it induced more inhibitory effects against all species. That suggests the possible use of palm leaf extracts against different pathogenic bacteria and fungi instead of chemical compounds, which had economic and health benefits.


Assuntos
Nanopartículas Metálicas , Phoeniceae , Antibacterianos/química , Antibacterianos/farmacologia , Antifúngicos/farmacologia , Nanopartículas Metálicas/química , Phoeniceae/química , Extratos Vegetais/química , Extratos Vegetais/farmacologia , Arábia Saudita , Prata/química , Prata/farmacologia , Árvores , Água
19.
Int J Biol Macromol ; 212: 337-347, 2022 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-35597379

RESUMO

To exploit the great fortune of date fruits, the current study aimed to valorize an Algerian common variety by extracting pectins. Response surface methodology (RSM) was applied as process optimization tool to achieve the highest yield using ultrasound-assisted extraction (UAE) as compared to conventional acid extraction (CAE). The experimental yield value (6.7%) was well matched with the predicted one (6.6%) at the optimum conditions (60 °C, 90 min, pH 1.5), confirming the validity of the model. The evaluation of the monomeric composition showed higher content of galacturonic acid and lower of neutral sugars in UAE pectin, as compared to CAE pectin. Conventional treatments decreased the molecular weight (Mw) of the extracted pectins (539 kDa) in a higher extent than ultrasound treatment (800 kDa). Fourier-Transform Infrared Spectroscopy (FT-IR) spectral analysis showed that both samples were low-methoxyl pectins. CAE gave rise to pectins with slightly upper technological samples in terms of water and oil holding capacity (5.2 and 3.8 g/g, respectively), and emulsifying activity (38.5 m2/g). Moreover, date pectins obtained by UAE presented enhanced antioxidant activity (24.3 and 61.0 mg/g DW for DPPH and FRAP assays, respectively), and in vitro antidiabetic properties, showing higher glucose adsorption capacity (4 mmol g-1 at 200 min), as well as α-amylase inhibition (73.7%) and potential capacity to decrease glucose diffusion (1.4 mmol mM g-1 at 150 min), which could improve the ability to retard starch digestion (0.1 mmol mM g-1 at 150 min), providing potential health-promoting properties.


Assuntos
Pectinas , Phoeniceae , Argélia , Antioxidantes/química , Antioxidantes/farmacologia , Glucose , Hipoglicemiantes/farmacologia , Pectinas/química , Pectinas/farmacologia , Espectroscopia de Infravermelho com Transformada de Fourier
20.
Bull Entomol Res ; 112(4): 494-501, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35382914

RESUMO

To counter the insect infestation, plants respond with wide-ranging and highly dynamic biochemical reactions. Of these, the anti-oxidative activity is poorly understood. The red palm weevil (RPW) Rhynchophorus ferrugineus (Oliver), one of the most widespread pests in Pakistan, prefers to infest date palm Phoenix dactylifera. Our present study investigated the feeding preference of RPW to 11 different date palm cultivars and the results suggested that the Hillawi cultivar was most preferred. Greater infestation rate, fecundity and hatching rate were also recorded from Hillawi and Mozawati than other cultivars. No significant decreases were observed in chlorophyll a, chlorophyll b, total chlorophylls and carotenoids of RPW-infested Hillawi cultivar over un-infested control. In contrast, the contents of enzymatic antioxidants including phenols, proline, hydrogen peroxide, anthocyanin, malondialdehyde, ascorbic acid and glycine betaine showed a drastic increase after RPW infestation, and there was enhanced superoxide dismutase, peroxidase and catalase activities. Furthermore, we recorded the increase of total protein and sugar contents in RPW-infested date palms. These findings offer valuable insight into the antioxidative molecular mechanism of date palms under RPW attack and may contribute to the breeding of insect-resistant crops.


Assuntos
Besouros , Phoeniceae , Gorgulhos , Animais , Clorofila A/metabolismo , Produtos Agrícolas , Gorgulhos/fisiologia
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