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2.
Rev Invest Clin ; 66 Suppl 1: S94-9, 2014 Jul.
Artigo em Espanhol | MEDLINE | ID: mdl-25264804

RESUMO

This research presents the development of a continual suction electromechanical device (CSED) which emulates the feeding characteristics of a medicinal leech to drain body fluids. After the research, design and building of the device, its performance in normal conditions with fluids of different viscosity was evaluated. Finally, the device was submitted to a test of blood draining in three adult male rabbits NZW with a weight of three kilograms, obtaining drain.


Assuntos
Drenagem/métodos , Sanguessugas , Aplicação de Sanguessugas/métodos , Animais , Líquidos Corporais/metabolismo , Desenho de Equipamento , Aplicação de Sanguessugas/instrumentação , Masculino , Coelhos , Viscosidade
7.
Arch Facial Plast Surg ; 5(1): 70-7, 2003.
Artigo em Inglês | MEDLINE | ID: mdl-12533144

RESUMO

OBJECTIVE: To test the effectiveness of a device designed to promote decongestion and tissue survival of a fasciocutaneous flap during 15 hours of complete venous obstruction. METHODS: In a porcine model, a 9 x 7-cm fasciocutaneous flap was elevated and the associated veins were clamped, causing complete venous obstruction for 15 hours in 6 control and 6 treatment animals. Up to 3 devices were used to treat the flap in a predetermined pattern. Control flaps were not treated. Measures of treatment efficacy included blood volumes removed; changes in skin color, surface perfusion, and tissue oxygen tension; and end point histologic findings. RESULTS: Control flaps were characterized by progressive darkening of skin color, undetectable surface perfusion, and low levels of oxygen tension. Histologic assessment showed severe congestion and extravasation of blood and distinct signs of necrosis. In contrast, treated flaps had significant improvements in skin color, surface perfusion, and subcutaneous oxygen tension. Histologic analysis showed little, if any, congestion and no signs of necrosis. Mean blood volume removed was 29.5 mL/h. CONCLUSION: The device was effective in decongesting a large area of tissue during 15 hours of complete outflow obstruction, based on quantitative measurements of tissue health and viability.


Assuntos
Volume Sanguíneo , Aplicação de Sanguessugas , Retalhos Cirúrgicos/irrigação sanguínea , Insuficiência Venosa/fisiopatologia , Insuficiência Venosa/terapia , Animais , Circulação Sanguínea/fisiologia , Cianose/terapia , Equipamentos e Provisões , Aplicação de Sanguessugas/instrumentação , Teste de Materiais/instrumentação , Teste de Materiais/métodos , Modelos Animais , Oxigênio/análise , Retalhos Cirúrgicos/patologia , Retalhos Cirúrgicos/fisiologia , Suínos , Sobrevivência de Tecidos/fisiologia , Resultado do Tratamento
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