Maturação placentária precoce / Early placental maturation

Os autores fazem uma revisão da literatura sobre o tema maturação placentária, com enfâse na maturação placentária precoce. Critérios diagnósticos, prognósticos e estratégias para monitoração fetal são discutidos. Artigos indexados nas bases de dados MEDLINE e LILACS de 1970 a 1997. Artigos com resultados de pesquisas originais. Revisão sistem[atica da bibliografia pesquisada...

Enfermedad trofoblastica gestacional

La presente revisión trata de la enfermedad trafoblástica gestacional haciendo referencia a los tumores de origen placentario que se derivan del tejido epitelial coriónico. Se describe la clasificación según la OMS, resaltando ls sintomatología clásica de esta patología, así como también los métodos de laboratorio más utilizados como son: La ecosonografía, La dosificación de HCG. Gamagrafía, TAC, estudios de histopatología, medición de alfa feto proteínas dosificación de calcio calmodulina y de CAMP-A quinasa, por último se revisan los esquemas terapéuticos más usados hoy en día.

Vasa previa.

Diagnosis of vasa previa requires a high index of suspicion. Vasa previa must be included in the differential diagnosis of all cases of third trimester bleeding. When pulsatile vessels are palpated preceding the fetal vertex, vasa previa should be considered along with cord prolapse. Early diagnosis and intervention result in a favorable fetal outcome in this rare condition.

[Effect of nutritional insufficiency on cell proliferation in the matrix zones of the cerebellar anlage in mice]. / Vliianie alimentarnoi nedostatochnosti na proliferatsiiu kletok matriksnykh zon zachatka mozzhechka myshei.

The work has been performed on 62 CBA mice. In the ventricular zone and in the external granular layer of the cerebellar anlage of embryos (13-17 days of the intrauterine development) mitotic index, labelled nuclei index, part of labelled mitoses have been counted. Parameters of the mitotic cycle of the matrix cells have been calculated by means of the graphic method. The proliferative pool value has been calculated. At malnutrition the cerebellar anlage structure retards in its maturation from the norm. For the matrix zones of the cerebellar anlage, higher indices of the proliferative activity are specific. At the same time, duration of the mitotic cycle of the matrix cells increases by 15-17%. It is possible, that retardation of histogenesis of the mouse cerebellar anlage, when developing under conditions of alimentary insufficiency depends on decreased rate of cell proliferation, as a result of prolonged mitotic cycle of the matrix cells.

[Pathological and embryological studies on abortion cases related to the Seveso accident]. / Pathologisch-embryologische Untersuchungen an Abortusfällen im Zusammenhang mit dem Seveso-Unglück.

After the explosion accident on July 10, 1976 in Seveso (Italy), material from 30 interrupted pregnancies and from 4 spontaneous abortions was investigated by embryological and histomorphological studies. No indications of mutagenic, teratogenic or fetotoxic effects of TCDD could be found. The cases of spontaneous abortion, albeit more suspect for dioxin damage, showed different morphological alterations obviously due to a variety of causative factors independent of TCDD. On the other hand it is not possible to exclude entirely an embryotoxic effect of TCDD because in the majority of cases the fetal tissues were incomplete.