RESUMO
BACKGROUND: Pain stemming from the placement of elastomeric separators and the exchanging of wires and accessories is the greatest reason for abandoning orthodontic treatment. Indeed, discomfort related to treatment exerts a negative impact on quality of life due to the difficulty chewing and biting. This paper proposes a study to evaluate the analgesic effects of photomiobodulation (PBM) on individuals undergoing orthodontic treatment. METHODS: The sample will be composed of 72 individuals who receiving elastomeric separators on the mesial and distal faces of the maxillary first molars. The patients will be randomly allocated to 2 groups: an experimental group irradiated with low-level laser and a sham group submitted to simulated laser irradiation. Upon the placement of the separators, the experimental group will receive a single application of PBM on the mesial and distal cervical portion and apical third of the molars. Perceived pain will be analyzed after one hour using the visual analog scale in both groups. Samples will be taken of the gingival crevice with absorbent paper for 30âseconds for the analysis of cytokines using ELISA and the results of the 2 groups will be compared. The patients will sign a statement of informed consent. Statistical analysis will be performed with the Student's t test and analysis of variance (ANOVA). DISCUSSION: The expectation is that the patients in the irradiated group will have a lower perception of pain and lower quantity of cytokines compared to those in the sham group. The purpose of the study is to establish an effective method for PBM with the use of low-level infrared laser (Ga-Al-As with a wavelength of 808ânm and output power of 100 mW) for reductions in pain and inflammatory cytokines related to orthodontic treatment. TRIAL REGISTRATION: This protocol was registered in ClinicalTrial.gov, under number NCT03939988. It was first posted and last updated in May 6, 2019.
Assuntos
Elastômeros/efeitos adversos , Terapia com Luz de Baixa Intensidade/métodos , Aparelhos Ortodônticos/efeitos adversos , Dor Processual/terapia , Técnicas de Movimentação Dentária/efeitos adversos , Adolescente , Adulto , Análise de Variância , Feminino , Humanos , Masculino , Dente Molar , Medição da Dor , Dor Processual/etiologia , Qualidade de Vida , Ensaios Clínicos Controlados Aleatórios como Assunto , Resultado do Tratamento , Adulto JovemRESUMO
BACKGROUND: The frequency of allergic contact dermatitis has significantly increased in healthcare workers since the transition from latex to synthetic rubber gloves, with 1,3-diphenylguanidine being identified as the most frequently implicated allergen. OBJECTIVES: To highlight the role of 1,3-diphenylguanidine as the culprit allergen in contact allergies to synthetic rubber gloves, to propose recommendations for patch testing, and to discuss alternatives for sensitized subjects. MATERIALS AND METHODS: Patch test data from healthcare workers who developed hand dermatitis after wearing rubber gloves and who reacted positively to glove samples and rubber additives were collected from September 2010 to December 2017 in a Belgian hospital. RESULTS: A total of 44 caregivers were included in this study. Patch tests showed that: (a) 84% of the study population reacted positively to carba mix; (b) 86% reacted positively to 1,3-diphenylguanidine; and (c) 13 (30%) reacted positively to thiuram mix. Half of the subjects reacted positively to gloves containing 1,3-diphenylguanidine, whereas none reacted to accelerator-free gloves. CONCLUSION: The most commonly identified allergen was 1,3-diphenylguanidine, far ahead of thiurams, which were previously described as the most sensitizing accelerators. The use of 1,3-diphenylguanidine-free gloves is recommended. No subject reacted to gloves without accelerators, thus confirming their efficiency among accelerator-sensitized patients. We recommend that 1,3-diphenylguanidine be added to the European baseline series.
Assuntos
Dermatite Alérgica de Contato/etiologia , Dermatite Ocupacional/etiologia , Elastômeros/efeitos adversos , Luvas Cirúrgicas/efeitos adversos , Guanidinas/efeitos adversos , Dermatoses da Mão/induzido quimicamente , Adulto , Ditiocarb/efeitos adversos , Feminino , Setor de Assistência à Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Testes do Emplastro , Tiram/efeitos adversos , Adulto JovemRESUMO
Various pressure-indicating media are available to assess the adaptation of the intaglio surface of a removable dental prosthesis at the insertion and follow-up appointments. This clinical report describes the use of an elastomer that entered the maxillary sinus through an undetected oroantral communication at the 24-hour follow-up for an immediate maxillary complete removable dental prosthesis. A Caldwell-Luc sinusotomy procedure was required to remove the material, and the patient required over 1 year of healing time before his reported symptoms resolved.
Assuntos
Retenção de Dentadura/efeitos adversos , Prótese Total Imediata/efeitos adversos , Prótese Total Superior/efeitos adversos , Prótese Parcial Removível/efeitos adversos , Elastômeros/uso terapêutico , Idoso , Adaptação Marginal Dentária , Retenção de Dentadura/métodos , Elastômeros/efeitos adversos , Humanos , Masculino , Seio Maxilar/diagnóstico por imagem , Seio Maxilar/cirurgia , Tomografia Computadorizada por Raios XRESUMO
A 14 day experiment on effects of visible implant elastomer (VIE) tagging and spine-clipping of three-spined stickleback Gasterosteus aculeatus showed significant increases in immune response, particularly in the granulocyte:lymphocyte ratio, in both treatments and the sham control. A minimum two-week recovery after handling, anaesthesia, tagging and spine-clipping is recommended to minimize effect of manipulation on the immune system.
Assuntos
Elastômeros/efeitos adversos , Smegmamorpha/imunologia , Estresse Fisiológico , Sistemas de Identificação Animal , Animais , Granulócitos/citologia , Linfócitos/citologia , Modelos BiológicosRESUMO
Pain resulting from the application of orthodontic forces varies markedly across individuals. The reasons of this variability are still largely unknown. To investigate factors that may be associated with orthodontic pain following the application of orthodontic separators. One hundred and seven participants were screened for pain response over 48 h following placement of orthodontic elastomeric separators. The highest (n = 10) and lowest (n = 10) pain responders were identified, and data collected on tooth pain sensitivity to electrical stimulation in conjunction with using the Pain Catastrophising Scale (PCS), Dental Anxiety Scale (DAS) and cold pressor test (CPT). There were statistically significant differences between high- and low-pain responders in catastrophising score (P ≤ 0.023). For every PCS magnification score of 1 unit higher, the relative risk of being a high-pain responder was 1.6 (P = 0.002); those scoring higher on helplessness had a lower risk of being so. DAS scores of high-pain responders were twice as high as those of low-pain responder (P = 0.043). During the first 2 min of CPT, the high-pain responders experienced more pain than the low-pain responders (P ≤ 0.029). Tooth pain thresholds did not differ between the two different pain responder groups. Pain catastrophising, dental anxiety and cold sensitivity appear to modify the pain experienced following placement of orthodontic separators. Further research is needed to determine the validity of screening questions to identify at-risk patients prior to commencing orthodontic treatment.
Assuntos
Elastômeros/efeitos adversos , Aparelhos Ortodônticos/efeitos adversos , Odontalgia/etiologia , Adulto , Temperatura Baixa/efeitos adversos , Estimulação Elétrica/efeitos adversos , Feminino , Humanos , Masculino , Medição da Dor/métodos , Fatores de Risco , Adulto JovemRESUMO
Owing to the extensive use of artificial turfs worldwide, over the past 10 years there has been much discussion about the possible health and environmental problems originating from styrene-butadiene recycled rubber. In this paper, the authors performed a Tier 2 environmental-sanitary risk analysis on five artificial turf sports fields located in the city of Turin (Italy) with the aid of RISC4 software. Two receptors (adult player and child player) and three routes of exposure (direct contact with crumb rubber, contact with rainwater soaking the rubber mat, inhalation of dusts and gases from the artificial turf fields) were considered in the conceptual model. For all the fields and for all the routes, the cumulative carcinogenic risk proved to be lower than 10(-6) and the cumulative non-carcinogenic risk lower than 1. The outdoor inhalation of dusts and gases was the main route of exposure for both carcinogenic and non-carcinogenic substances. The results given by the inhalation pathway were compared with those of a risk assessment carried out on citizens breathing gases and dusts from traffic emissions every day in Turin. For both classes of substances and for both receptors, the inhalation of atmospheric dusts and gases from vehicular traffic gave risk values of one order of magnitude higher than those due to playing soccer on an artificial field.
Assuntos
Butadienos/efeitos adversos , Butadienos/análise , Elastômeros/efeitos adversos , Elastômeros/análise , Exposição Ambiental/análise , Poluentes Ambientais/análise , Estirenos/efeitos adversos , Estirenos/análise , Benzeno/efeitos adversos , Benzeno/análise , Exposição Ambiental/efeitos adversos , Poluentes Ambientais/efeitos adversos , Humanos , Itália , Modelos Teóricos , Tamanho da Partícula , Reciclagem , Medição de Risco , Futebol , Tolueno/efeitos adversos , Tolueno/análise , Xilenos/efeitos adversos , Xilenos/análiseRESUMO
This article reports the case of a 12-year-old patient with tooth extrusion, pain, gingival bleeding, and localized periodontitis near the maxillary second premolar. Despite probing and radiographic examination, it was not possible to establish the etiology. Tooth extraction was indicated because of the severe tooth mobility and extrusion. Curettage of the tooth socket revealed a rubber separator. Preventive approaches are suggested to avoid iatrogenesis and legal problems.
Assuntos
Dente Pré-Molar/fisiopatologia , Corpos Estranhos , Aparelhos Ortodônticos/efeitos adversos , Alvéolo Dental , Odontalgia/etiologia , Criança , Elastômeros/efeitos adversos , Humanos , Masculino , Maxila , Extração Dentária , Mobilidade Dentária/cirurgia , Odontalgia/cirurgiaRESUMO
OBJECTIVE: Cytokeratin 18 (CK18) is a novel serologic biomarker for occupational liver disease. The purpose of this study is to determine the prevalence of CK18 elevation in elastomer/polymer workers exposed to acrylonitrile, 1,3-butadiene, and styrene. METHODS: A total of 82 chemical workers were evaluated. Cytokeratin 18 was determined by enzyme-linked immunosorbent assay and proinflammatory cytokines were measured by multi-analyte chemiluminescent detection. RESULTS: Thirty-nine percent (32 of 82) had elevated CK18 levels, which were not explained by alcohol or obesity, except in potentially four cases. The pattern of CK18 elevation was consistent with toxicant-associated steatohepatitis (TASH) in the majority of cases (78%). Tumor necrosis factor α, interleukin-6, interleukin-8, monocyte chemotactic protein-1, and plasminogen activator inhibitor-1 were increased in these workers compared with those with normal CK18 levels. CONCLUSIONS: These results suggest a high prevalence of occupational liver disease and TASH in elastomer/polymer workers with elevated proinflammatory cytokines.
Assuntos
Acrilonitrila/efeitos adversos , Butadienos/efeitos adversos , Doença Hepática Induzida por Substâncias e Drogas/sangue , Citocinas/sangue , Fígado Gorduroso/sangue , Queratina-18/sangue , Doenças Profissionais/sangue , Estireno/efeitos adversos , Adulto , Quimiocina CCL2/sangue , Elastômeros/efeitos adversos , Fígado Gorduroso/induzido quimicamente , Humanos , Interleucina-1/sangue , Interleucina-6/sangue , Modelos Lineares , Testes de Função Hepática , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/induzido quimicamente , Inibidor 1 de Ativador de Plasminogênio/sangue , Polímeros/efeitos adversos , Estatísticas não Paramétricas , Fator de Necrose Tumoral alfa/sangueRESUMO
Many hospitals have implemented policies to restrict or ban the use of devices made of natural rubber latex (NRL) in healthcare as precautionary measures against the perceived risk of NRL allergy. Changes in glove technology, progress in measuring the specific allergenic potential of gloves and a dramatic decrease in the prevalence of NRL allergies after interventions and education prompted us to revisit the basis for justifiable glove selection policies. The published Anglophone literature from 1990 to 2010 was reviewed for original articles and reviews dealing with the barrier and performance properties of NRL and synthetic gloves and the role of glove powder. The review shows that NRL medical gloves, when compared with synthetic gloves, tend to be stronger, more flexible and better accepted by clinicians. The introduction of powder-free gloves has been associated with reductions in protein content and associated allergies. Recently, new methods to quantify clinically relevant NRL allergens have enabled the identification of gloves with low allergenic potential. The use of low-protein, low-allergenic, powder-free gloves is associated with a significant decrease in the prevalence of type I allergic reactions to NRL among healthcare workers. Given the excellent barrier properties and operating characteristics, dramatically reduced incidences of allergic reactions, availability of specific tests for selection of low-allergen gloves, competitive costs and low environmental impact, the use of NRL gloves within the hospital environment warrants reappraisal.
Assuntos
Elastômeros/efeitos adversos , Luvas Cirúrgicas , Hipersensibilidade ao Látex/epidemiologia , Pós/efeitos adversos , Luvas Cirúrgicas/economia , Pessoal de Saúde , Hospitais/normas , Humanos , Látex/efeitos adversos , Látex/imunologia , Hipersensibilidade ao Látex/economia , Hipersensibilidade ao Látex/imunologiaRESUMO
PURPOSE: Measures to improve the safe implementation and utilization of an elastomeric infusion system for pain management are described. SUMMARY: Due to the multiple safety concerns associated with the use of the On-Q infusion systems (I-Flow Corporation, Lake Forest, CA) in a community-based teaching institution, a multidisciplinary team of physicians, pharmacists, clinical nurses, nurse educators, and computer informatics personnel was formed to develop a standardized policy and procedure to ensure the safe use of On-Q pumps. The policy addressed several problems concerning prescribing, dispensing, administration, and monitoring of these pumps. The patient care policy for use of On-Q pumps dictates how the pumps are stocked, ordered, dispensed, administered, and monitored and the drugs approved for use in the pumps. Education bulletins, a summary of the new policy and procedure, and a formal presentation of the policy and procedure to unit-based nurse educators were provided. The focus was on a consistent message of safety by reiterating the problems described with these pumps in the literature and in the health care system itself. The physicians ordering the devices have provided positive feedback regarding the simplified ordering process and standardization of the pumps, medications, and concentrations. Both dispensing pharmacists and bedside nurses have noted that the orders are clearly communicated via the computerized system. The addition of documentation in the computer system and education regarding potential signs and symptoms of adverse events with the medication used with the pumps was greatly appreciated by the nursing staff. CONCLUSION: A health care system instituted measures to enhance the safety of using an elastomeric infusion system for pain management.
Assuntos
Controle de Medicamentos e Entorpecentes/métodos , Bombas de Infusão/efeitos adversos , Dor/tratamento farmacológico , Serviço de Farmácia Hospitalar/métodos , Bupivacaína/administração & dosagem , Bupivacaína/efeitos adversos , Sistemas de Liberação de Medicamentos/efeitos adversos , Sistemas de Liberação de Medicamentos/métodos , Sistemas de Liberação de Medicamentos/normas , Elastômeros/administração & dosagem , Elastômeros/efeitos adversos , Humanos , Bombas de Infusão/normas , Dor/metabolismo , Farmacêuticos/normas , Serviço de Farmácia Hospitalar/normas , SegurançaRESUMO
In this study we investigate the potential of femtosecond laser generated micrometer sized spike structures as functional surfaces for selective cell controlling. The spike dimensions as well as the average spike to spike distance can be easily tuned by varying the process parameters. Moreover, negative replications in soft materials such as silicone elastomer can be produced. This allows tailoring of wetting properties of the spike structures and their negative replicas representing a reduced surface contact area. Furthermore, we investigated material effects on cellular behavior. By comparing human fibroblasts and SH-SY5Y neuroblastoma cells we found that the influence of the material was cell specific. The cells not only changed their morphology, but also the cell growth was affected. Whereas, neuroblastoma cells proliferated at the same rate on the spike structures as on the control surfaces, the proliferation of fibroblasts was reduced by the spike structures. These effects can result from the cell specific adhesion patterns as shown in this work. These findings show a possibility to design defined surface microstructures, which could control cellular behavior in a cell specific manner.
Assuntos
Materiais Biocompatíveis/química , Fenômenos Fisiológicos Celulares , Lasers , Silício/química , Materiais Biocompatíveis/efeitos adversos , Materiais Biocompatíveis/metabolismo , Adesão Celular , Linhagem Celular Tumoral , Proliferação de Células , Dano ao DNA , Elastômeros/efeitos adversos , Elastômeros/química , Elastômeros/metabolismo , Fibroblastos/citologia , Fibroblastos/metabolismo , Humanos , Testes de Mutagenicidade , Nanoestruturas/química , Nanoestruturas/ultraestrutura , Neuroblastoma/metabolismo , Silício/efeitos adversos , Silício/metabolismo , Propriedades de Superfície , Fatores de TempoRESUMO
This case report is of maxillary central incisors still in place 38 years after periodontal surgery to correct the damage to supporting tooth structure caused by an orthodontic elastic band.
Assuntos
Aparelhos Ortodônticos/efeitos adversos , Atrofia Periodontal/etiologia , Atrofia Periodontal/cirurgia , Adolescente , Diastema/terapia , Elastômeros/efeitos adversos , Feminino , Seguimentos , HumanosRESUMO
OBJECTIVES: To evaluate patients' perceptions of pain and discomfort during tooth separation and to compare the effectiveness of brass wire and elastomeric separators. METHODS: The participants were 87 adults with a mean age of 22.1 +/- 1.9 years. Elastomeric and brass wire separators were inserted mesial and distal to upper right (elastomeric separators) and upper left first molars (brass wire separators) in each subject. After seven days, the amount of tooth separation was measured with a leaf gauge, and pain perception and discomfort were evaluated with a visual analogue scale and questionnaire. RESULTS: The elastomeric separators produced significantly more separation than the wire separators. There was a statistically significant difference in the subjects' perceptions of pain and discomfort at rest and during chewing between the different separators (p < 0.001). In general, the brass wire separators caused the greatest pain and discomfort immediately after insertion. Pain from the wire separators subsided over seven days, whereas elastomeric separators caused the greatest pain on the first two days after insertion. Eating was negatively influenced by the separation in 61 per cent of the subjects on the first day. On the other hand, other daily activities were affected minimally. CONCLUSIONS: The different levels of pain and discomfort caused by these separators, together with their advantages and disadvantages, can help the clinician to choose an appropriate separator. Patients should be warned that pain due to separation may affect their chewing, social life, school work and sleeping. Analgesics and soft food are recommended following placement of separators.
Assuntos
Dor Facial/etiologia , Dor Facial/psicologia , Técnicas de Movimentação Dentária/efeitos adversos , Técnicas de Movimentação Dentária/instrumentação , Adolescente , Adulto , Elastômeros/efeitos adversos , Feminino , Humanos , Masculino , Mastigação , Fios Ortodônticos/efeitos adversos , Medição da Dor , Percepção , Inquéritos e Questionários , Adulto JovemAssuntos
Exposição Ambiental/efeitos adversos , Polímeros/efeitos adversos , Elastômeros/efeitos adversos , Elastômeros/química , Exposição Ambiental/legislação & jurisprudência , Humanos , Exposição por Inalação/efeitos adversos , Exposição por Inalação/legislação & jurisprudência , Polímeros/química , Esportes , Gerenciamento de ResíduosAssuntos
Alérgenos , Dermatite Alérgica de Contato/diagnóstico , Testes do Emplastro , Adesivos/efeitos adversos , Vestuário/efeitos adversos , Dermatite Alérgica de Contato/etiologia , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos , Elastômeros/efeitos adversos , Produtos Domésticos/efeitos adversos , Humanos , Hipersensibilidade ao Látex/prevenção & controle , Metais/efeitos adversos , Perfumes/efeitos adversos , Perfumes/química , Preparações Farmacêuticas/químicaRESUMO
Allergic reactions associated with silicone injection and implant were examined in a 50-year-old woman with a granulomatous reaction following breast silicone-gel prosthesis rupture who developed a delayed hypersensitivity to rubber compounds. Patch tests with SIDAPA, dental, and rubber series as well as open tests with latex, silicone and non silicone tubes, open application test with silicone gel, and skin prick test for aero and food-allergens were performed. Total and specific serum IgE measured by CAP-FEIA. Skin tests revealed a delayed-type hypersensitivity to thioureas, thiuram mixture and platinum. Specific IgE to natural rubber latex were found. Allergic contact dermatitis from thioureas, thiurams and platinum might be under-diagnosed, as they are not tested as part of the standard patch test series. Clinicians should consider this diagnosis in patients submitted to several cosmetic treatments.
Assuntos
Implante Mamário/efeitos adversos , Implantes de Mama/efeitos adversos , Dermatite Alérgica de Contato/etiologia , Elastômeros/efeitos adversos , Hipersensibilidade Tardia/induzido quimicamente , Géis de Silicone/efeitos adversos , Mama/cirurgia , Dermatite Alérgica de Contato/patologia , Feminino , Humanos , Hipersensibilidade ao Látex/patologia , Pessoa de Meia-Idade , Falha de Prótese , Testes CutâneosRESUMO
The stability and tight integration into adjacent tissue of a novel, degradable, elastic copolymer were examined in an animal model. The biomaterial was used for the reconstruction of a gastric wall defect in Sprague-Dawley rats (n=42) to test the polymeric material under the extreme chemical, enzymatical and mechanical conditions of the stomach. In the control group (n=21) the same defect of the gastric wall was primarily closed without biomaterial implantation. In the baseline group (n=21) the animals were kept under standard conditions without any surgical procedure. The implantation periods were 1 week, 4 weeks and 6 months. The animals' weight was determined preoperatively and before explantation. After explantation, air was pumped into the stomach and the pressure was measured by using a pressure-gauge in order to test whether the surgically produced union of the stomach wall and the polymer patch was gas-tight. After 1 week of implantation time a statistically significant increase of the body weight of the animals was found only in the baseline group. Four weeks and 6 months after the abdominal surgical procedure, a statistically significant increase of the animals' weight was found in the implantation group, the control and the baseline group. Gastrointestinal complications like fistula, perforation or peritonitis did not occur in any of the animals. The measurement of the stomach pressure after maximal gas insufflation did not show significant differences between the implantation group, the control and the baseline group in any of the time periods investigated. Despite very high strains of the gastric wall, no gas leakage was detected. There was a tight connection between the polymer and the adjacent stomach wall in all animals investigated. An adequate mechanical stability of the biomaterial was detectable under the extreme pathophysiological conditions of the stomach milieu. A fast and unfavourable degradation of the degradable polymer was not found in any of the animals. Further investigations are needed to analyse the mechanisms of the tissue integration of the biomaterial as well as the degradation kinetic of the polymer and the process of the tissue remodeling. The knowledge of these processes is necessary to adapt the novel biomaterial and thus prepare it for the use and implantation in different body locations and to develop novel therapeutical options in medicine.
Assuntos
Implantes Absorvíveis , Materiais Biocompatíveis/química , Elastômeros/química , Estômago/lesões , Estômago/cirurgia , Animais , Materiais Biocompatíveis/efeitos adversos , Modelos Animais de Doenças , Elastômeros/efeitos adversos , Análise de Falha de Equipamento , Masculino , Teste de Materiais , Projetos Piloto , Desenho de Prótese , Ratos , Ratos Sprague-Dawley , Estômago/patologiaRESUMO
Fixed or removable orthodontic appliances impede the maintenance of oral hygiene and result in plaque accumulation. Plaque retention surrounding orthodontic appliances leads to enamel demineralization caused by organic acids produced by bacteria in the dental plaque. Many studies have evaluated the effects of fixed orthodontic appliances on microbial flora and periodontal status, but only a few have evaluated the method of ligation as an additional factor. The aim of this study was to determine the changes in microbial flora and periodontal status after orthodontic bonding and to determine whether two different archwire ligation techniques affect these changes. A total of 21 orthodontic patients scheduled for fixed orthodontic treatment were selected for this split-mouth study. Two commonly used auxiliaries (elastomeric rings and ligature wires) for tying archwires were tested. Microbial and periodontal records were obtained before bonding (T0), one week later (T1), and five weeks after bonding (T2). Paired t-test and Wilcoxon signed rank test were used to compare the groups statistically. Although, teeth ligated with elastomeric rings exhibited slightly greater numbers of microorganisms than teeth ligated with steel ligature wires, the differences were not statistically significant and could be ignored. The two archwire ligation techniques showed no significant differences in the gingival index, bonded bracket plaque index, or pocket depths of the bonded teeth. However, teeth ligated with elastomeric rings were more prone to bleeding. Therefore, elastomeric ring use is not recommended in patients with poor oral hygiene.
Assuntos
Placa Dentária/microbiologia , Aparelhos Ortodônticos/efeitos adversos , Adolescente , Adulto , Criança , Contagem de Colônia Microbiana , Placa Dentária/etiologia , Índice de Placa Dentária , Elastômeros/efeitos adversos , Feminino , Hemorragia Gengival/etiologia , Humanos , Lactobacillus/isolamento & purificação , Masculino , Fios Ortodônticos/efeitos adversos , Índice Periodontal , Estatísticas não Paramétricas , Streptococcus mutans/isolamento & purificaçãoRESUMO
BACKGROUND: Patients with fixed orthodontic appliances often experience an absolute increase in the number of Streptococci mutans colony-forming units (cfu). The aim of this investigation was to study the development of biofilm and S. mutans cfu in connection with stainless steel ligatures and elastomeric rings in orthodontic patients treated with and without 0.4% stannous fluoride gel (SFG). MATERIAL: Forty-seven patients were divided into 2 groups: those treated with 0.4% SFG for 4 minutes (experimental) and those without 0.4% SFG (control). In each patient, elastomeric rings were used for ligation on 1 side of the dental arch midline, and stainless steel ligatures were used on the opposite side. Saliva samples were collected before and after appliance placement. At 15 and 30 days after appliance placement, biofilm samples from the stainless steel ligatures and the elastomeric rings were collected and subjected to microbiologic procedures and scanning electron microscopy (SEM) analysis. RESULTS: The numbers of S. mutans cfu in the saliva and biofilm were not statistically different between the teeth fitted with elastomeric rings and stainless steel ligatures, or between the experimental and control groups. SEM analysis showed biofilm formation on both ligature ties. CONCLUSIONS: Topical application of 0.4% SFG in orthodontic patients with elastomeric rings or stainless steel ligatures does not cause a significant decrease in S. mutans cfu in the saliva and biofilm.
Assuntos
Biofilmes/efeitos dos fármacos , Cariostáticos/administração & dosagem , Placa Dentária/microbiologia , Aparelhos Ortodônticos/efeitos adversos , Streptococcus mutans/efeitos dos fármacos , Fluoretos de Estanho/administração & dosagem , Adolescente , Análise de Variância , Criança , Contagem de Colônia Microbiana , Placa Dentária/etiologia , Elastômeros/efeitos adversos , Feminino , Géis , Humanos , Masculino , Microscopia Eletrônica de Varredura , Fios Ortodônticos/efeitos adversos , Saliva/microbiologiaRESUMO
The author reviews his personal experience using additive mastoplastics with the hydrogel prosthesis produced in France by Arion. The enumeration of cases covers 143 patients (285 prosthesis) with 36 months of follow-up evaluation. The positive aspects of this filling (especially the radiotransparency) and its complications are considered, with special attention paid to the wrinkling effect that may be caused by some physical instability of the hydrogel. The well-known controversy of 1992 concerning silicon mammary prostheses encouraged scientists to seek alternative solutions in the field of prosthetic extenders. This effort sometimes produced negative solutions such as the soya oil prosthesis, but at the same time provided materials with excellent physical-chemical qualities, with subsequent positive effects from a clinical point of view. This work is dedicated to one of these products, the Arion hydrogel. After 6-years of utilization with a 36-month follow-up period, 285 prosthesis have been fitted for 143 patients.