Hipodermóclise como tecnologia integrativa ao processo infusional em crianças / Hypodermoclysis as an integrative technology for the infusion process in children / Hipodermoclisis como tecnología integradora para el proceso de infusión en niños

Objetivo: Identificar as evidências científicas acerca da efetividade e da segurança da hipodermóclise em comparação à via intravenosa, no processo de infusão de fluidos, para reidratação de crianças até 10 de idade, com leve a moderada desidratação, nos contextos hospitalares e domiciliares. Métodos: Revisão sistemática conduzida conforme as recomendações do Instituto Joanna Briggs®, com protocolo publicado e registrado. A busca foi realizada em cinco recursos informacionais diferentes (bases de dados, literatura cinzenta, referências dos estudos). Todo o processo de seleção foi conduzido por revisores independentes. Resultados: Foram identificados 1410 estudos e dois foram incluídos na análise. Devido a heterogeneidade dos estudos não foi possível a realização da meta-análise. Os desfechos analisados foram volume total de líquido infundido, alteração da desidratação conforme escala de Gorelick e peso, número de tentativas para inserção do cateter, e eventos adversos. Conclusão: Demonstra-se benefícios do uso da hipodermóclise como prática integrativa ao processo de infusão de fluidos em crianças, porém com baixo nível de evidência. Novas pesquisas com alta qualidade metodológica serão promissoras para sua implementação no cuidado ao paciente pediátrico. (AU)

Objective: To identify scientific evidence about the effectiveness and safety of hypodermoclysis compared to the intravenous route, in the fluid infusion process, for rehydration of children up to 10 years of age, with mild to moderate dehydration, in hospital and home settings. Methods: Systematic review conducted according to the recommendations of the Joanna Briggs® Institute, with a published and registered protocol. The search was performed in six databases, five gray literature databases, and references of the included studies. The entire selection process was conducted by independent reviewers. Results: 1410 studies were identified and two were included in the analysis. Due to the heterogeneity of the studies, it was not possible to carry out the meta-analysis. The outcomes analyzed were total volume of fluid infused, change in dehydration according to the Gorelick scale and weight, number of attempts to insert the catheter, and adverse events. Conclusion: Benefits of the use of hypodermoclysis as an integrative practice in the fluid infusion process in children are demonstrated, but with a low level of evidence. New research with high methodological quality will be promising for its implementation in pediatric patient care. (AU)

Objetivo: Identificar evidencia científica sobre la efectividad y seguridad de la hipodermoclisis en comparación con la vía intravenosa, en el proceso de infusión de líquidos, para la rehidratación de niños hasta los 10 años de edad, con deshidratación leve a moderada, en el ámbito hospitalario y domiciliario. Métodos: Revisión sistemática realizada de acuerdo con las recomendaciones del Instituto Joanna Briggs®, con protocolo publicado y registrado. La búsqueda se realizó en seis bases de datos, cinco bases de datos de literatura gris y referencias de los estudios incluidos. Todo el proceso de selección fue realizado por revisores independientes. Resultados: Se identificaron 1410 estudios y se incluyeron dos en el análisis. Debido a la heterogeneidad de los estudios, no fue posible realizar el metanálisis. Los resultados analizados fueron el volumen total de líquido infundido, el cambio en la deshidratación según la escala y el peso de Gorelick, el número de intentos de insertar el catéter y los eventos adversos. Conclusión: Se demuestran los beneficios del uso de la hipodermoclisis como práctica integradora en el proceso de infusión de líquidos en niños, pero con un bajo nivel de evidencia. Nuevas investigaciones con alta calidad metodológica serán prometedoras para su implementación en la atención del paciente pediátrico. (AU)

Teorias de enfermagem utilizadas em pediatria / Nursing theories used in pediatrics / Teorías de enfermería utilizadas en pediatría

Objetivo: Mapear as teorias de enfermagem utilizadas nos diferentes contextos de assistência à criança e ao adolescente. Métodos: Revisão de escopo de acordo com a metodologia do Instituto Joanna Briggs, que incluiu estudos primários, publicados em inglês, espanhol e português, sem restrição de tempo, e disponibilizados nas bases de dados MEDLINE, WOS, BDENF, SCOPUS, CINAHL e SCIELO. Resultados: Foram incluídos nesta revisão 53 artigos, os quais evidenciaram 17 teorias de enfermagem aplicadas aos mais diversos contextos pediátricos, como hospitalização, terapia intensiva, cuidados para doenças crônicas e promoção da saúde. A teoria mais utilizada para direcionar o cuidado foi a Teoria da Adaptação de Roy. São várias as experiências exitosas no campo da pesquisa e prática assistencial com a utilização das teorias de enfermagem. Conclusão: Diferentes teorias de enfermagem embasam o cuidado de enfermagem pediátrica; e a escolha de cada teoria deve ser norteada por um propósito explícito ou assunto de interesse dos autores, com base em suas expectativas pessoais e nas evidências científicas. Por meio deste estudo foi possível vislumbrar o potencial de cada teoria para subsidiar a prática da enfermagem pediátrica. (AU)

Objective: To map the Nursing theories used in the different contexts of assistance to children and adolescents. Methods: Scoping review according to the Joanna Briggs Institute methodology and included primary studies, published in English, Spanish and Portuguese, with no time restrictions, and made available in the MEDLINE, WOS, BDENF, SCOPUS, CINAHL and SCIELO databases. Results: A total of 53 articles were included in this review, which evidenced 17 Nursing theories applied to the most varied pediatric contexts, such as hospitalization, intensive care, care for chronic conditions, and health promotion. The theory most used to direct care was the Roy's Adaptation Theory. There are several successful experiences in the field of research and care practice with the use of Nursing theories. Conclusion: Different Nursing theories support pediatric Nursing care; and the choice of each theory must be guided by an explicit purpose or subject of interest to the authors, based on their personal expectations and on the scientific evidence. Through this study it was possible to glimpse the potential of each theory to support pediatric Nursing practice. (AU)

Objetivo: Mapear las teorías de Enfermería utilizadas en los diferentes contextos de atención a la niñez y adolescencia. Métodos: Revisión de alcance según la metodología del Joanna Briggs Institute que incluyó estudios primarios, publicados en inglés, español y portugués, sin restricciones de tiempo, y disponibles en las bases de datos MEDLINE, WOS, BDENF, SCOPUS, CINAHL y SCIELO. Resultados: En esta revisión se incluyeron un total de 53 artículos, que evidenciaron 17 teorías de enfermería aplicadas a los más variados contextos pediátricos, como hospitalización, cuidados intensivos, cuidados de enfermedades crónicas y promoción de la salud. La teoría más utilizadas para dirigir el cuidado fue la Teoría de la Adaptación de Roy. Existen varias experiencias exitosas en el campo de la investigación y la práctica asistencial con el uso de las teorías de Enfermería. Conclusión: Diferentes teorías de Enfermería sustentan la atención de Enfermería pediátrica; y la elección de cada teoría debe estar guiada por un propósito explícito o tema de interés para los autores, con base en sus expectativas personales y en la evidencia científica.A través de este estudio se pudo vislumbrar el potencial de cada teoría para sustentar la práctica de la Enfermería pediátrica. (AU)

Advancing Pediatric Care: The virtualKIDS Experience in Nursing-Led Audio-Visual Clinical Services.

During the COVID-19 pandemic, the escalating trend of pediatric patients, particularly non-urgent cases, going to the emergency departments (EDs) in New South Wales, Australia, prompted the establishment of virtualKIDS, a nursing-led telehealth service. This service, initiated in June 2021, operates 24/7 and provides comprehensive care through audio-visual consultations emphasizing a patient-centered approach. Three elements-COVID-19 Outpatient Response Team (CORT), virtualKIDS Acute Review (vKAR), and Virtual Urgent Care (VUC)-addressed specific needs during and beyond the pandemic, showcasing the adaptability and impact of virtual care. vKAR focuses on post-discharge support, allowing families access to telehealth for up to three days. Preliminary data indicates a 44% reduction in ED visits within 48 h. VUC employs nursing-led triaging paired with audiovisual assessment, demonstrating a 69% hospitalization avoidance rate. Hybrid ambulatory models such as a sleep study at home project, day-only tonsillectomies, and arthroscopic knee surgeries showcase innovative approaches to reducing hospital admissions and enhancing patient outcomes. This paper presents the evolution and diverse models of care implemented by the virtualKIDS service, offering insights into its potential as a nursing-led alternative to ED visits in acute-care pediatrics.

Pain management in hospitalized children: unveiling barriers from the nursing perspective.

OBJECTIVE: To understand nursing team perceptions about the barriers in pain management in the care of hospitalized children. METHOD: Descriptive-exploratory study, with a qualitative approach, conducted with eight nurses and seven nursing technicians. Data were collected at the Universidade de São Paulo University Hospital, between June and September 2022, through individual interviews, analyzed from the perspective of thematic content analysis and in the light of Symbolic Interactionism. RESULTS: The following categories emerged: 1) Knowledge translation: is pain management actuallyperformed? and 2) Reflecting changes: how to achieve the potential of pain management? Professionals have theoretical knowledge about pain management, however, they listed numerous barriers at each stage, mainly related to institutional routine, and, when reflecting on this context, they indicated the need for an institutional protocol. FINAL CONSIDERATIONS: Barriers stand out from theoretical knowledge and make pain management for hospitalized children disregarded. Knowing this context is relevant forimplementing change strategies.

What the pediatric nurse needs to know about the Impella cardiac assist device.

Background: Cardiogenic shock in children still carries a high mortality risk despite advances in medical therapy. The use of temporary mechanical circulatory supports is an accepted strategy to bridge patients with acute heart failure to recovery, decision, transplantation or destination therapy. These devices are however limited in children and extracorporeal membrane oxygenation (ECMO) remains the most commonly used device. Veno-arterial ECMO may provide adequate oxygen delivery, but it does not significantly unload the left ventricle, and this may prevent recovery. To improve the likelihood of left ventricular recovery and minimize the invasiveness of mechanical support, the Impella axial pump has been increasingly used in children with acute heart failure in the last decade. Purpose: There are still limited data describing the Impella indications, management and outcomes in children, therefore, we aimed to provide a comprehensive narrative review useful for the pediatric nurses to be adequately trained and acquire specific competencies in Impella management.

Development and Implementation of a Pediatric Nursing Emergency Behavioral Health Assessment Tool.

INTRODUCTION: The national pediatric mental and behavioral health crisis dramatically increased emergency department mental and behavioral health visits and changed emergency nursing practice. Acuity assessment determines patient severity level and supports appropriate resources and interventions. There are no established nursing tools that assess pediatric mental or behavioral health acuity in the emergency department setting. Our goal was to develop and implement the novel pediatric emergency nurse Emergency Behavioral Health Acuity Assessment Tool. METHODS: This quality-improvement project used the plan, do, study, act model to design/refine the Emergency Behavioral Health Acuity Assessment Tool and a non-experimental descriptive design to assess outcomes. The setting was a 47-bed urban level 1 pediatric trauma center with more than 60,000 annual visits. The team designed the tool using published evidence, emergency nurse feedback, and expert opinion. The tool objectively captured patient acuity and suggested acuity-specific nursing interventions. Project outcomes included acuity, length-of-stay, restraint use, and patient/staff injuries. Analyses included descriptive statistics and correlations. RESULTS: With over 3000 annual mental/behavioral-related visits, the emergency department had an average daily census of 23 mental and behavioral health patients. Implementation occurred in August 2021. The Emergency Behavioral Health Acuity Assessment Tool dashboard provided the number of patients, patient location, and acuity. Length-of-stay did not change; however, patient restraint use and patient/staff injuries declined. Number of restraints positively correlated with moderate acuity levels (r = 0.472, P = 0.036). DISCUSSION: For emergency nurses, the Emergency Behavioral Health Acuity Assessment Tool provided an objective measure of patient acuity. Targeted interventions can improve the care of this population.

Opportunities to Diversify the Pediatric Nursing Workforce: A Focus on Male Nurses.

INTRODUCTION: Pediatric nursing has been a profession dominated by women, but patients benefit from representation of both men and women. We describe characteristics associated with male pediatric nurses and consider potential pathways to greater male pediatric nurse workforce participation. METHOD: We used data from the 2018 National Sample Survey of Registered Nurses, a nationally representative survey of nurses that estimates characteristics of the workforce. We present summary statistics to describe demographic, work setting and work environment characteristics of male and pediatric nurse workforces. Analyses accounted for complex survey design and weighting. RESULTS: Only 7% (N = 108,752) of the pediatric registered nurse workforce and 3% (N = 779) of the pediatric nurse practitioner workforces were male. Notable demographic and educational difference exist among compared workforces. DISCUSSION: Males are significantly underrepresented in pediatric nursing. Much effort and intention need to be directed towards increasing male representation in pediatric nursing.

Discursive analysis of nursing care toward childhood fever and its contextual differences: An ethnomethodological study.

Fever is the most common clinical sign during infancy. Nurses deal with fever in children most directly and it is an integral aspect of their role as pediatric nurses. The objective of this study is to analyze the perceptions, knowledge and attitudes toward childhood fever of nurses in three health contexts: pediatric hospitalization, pediatric emergency and primary care. To respond this objective, a qualitative study with ethnomethodological approach has been carried out. In-depth interviews were conducted and theoretical clinical cases were presented to nurses working in pediatrics in the three settings studied. After the analysis of the discourses, the codes were classified into three categories: static and number-centric knowledge, dependent nursing attitude, and unconscious model nurses. On the one hand, when we analyze and compare the perceptions, attitudes and knowledge of the nurses between the different contexts, we find differences that consist mainly of what the context requires of them. On the other hand, in general and regardless of the context, the nurses interviewed place themselves in a traditional framework when faced with the phenomenon of fever in children.

The effect of serious game and problem-based learning on nursing students' knowledge and clinical decision-making skill regarding the application of transfusion medicine in pediatric nursing.

PURPOSE: Comparing the effect of serious game and problem-based learning on nursing students' knowledge and clinical decision-making skill regarding the application of transfusion medicine in pediatric nursing. DESIGN AND METHODS: In this quasi-experimental study, 76 undergraduate nursing students were enrolled through a convenience sampling method, and were allocated to one of the three groups of serious game, problem-based learning, and control through the block randomization method. Data were collected using a valid and reliable 3-part researcher-made tool, completed before and two weeks after the intervention. Statistical analysis was performed using paired t-test, analysis of covariance, and Bonferroni post hoc test. A significance level of <0.05 was considered. RESULTS: After the intervention, mean scores of both knowledge and clinical decision-making skill increased significantly in both intervention groups (p < 0.05). Mean post-test scores of both knowledge and clinical decision-making skill in the serious game group, and only clinical decision-making skill in the problem-based learning group were significantly higher than the control group (p < 0.05). However, no significant difference was observed regarding mean post-test scores of both knowledge and clinical decision-making skill between the intervention groups (p > 0.05). CONCLUSIONS: Both serious game and problem-based learning are proven to be effective in improving nursing students' knowledge and clinical decision-making skill regarding the application of transfusion medicine in pediatric nursing. PRACTICE IMPLICATIONS: Since learning now occurs beyond classrooms and the new generation of students spend most of their time in virtual places, utilizing technology-based teaching methods like serious games can benefit both educators and students by providing continuous education, saving their time and expenses, etc.

Research on Family-Centered Care in pediatric patients: A Bibliometric Analysis.

OBJECTIVE: This study is conducted as a bibliometric analysis to determine the trends in studies related to family-centered care in children. MATERIALS AND METHODS: The Web of Science database was used to collect study data. A search was conducted on Web of Science using the keywords "family-centered care", "family centered care", "family-centred care", "family centred care", "family-integrated care", "family integrated care", "patient and family centered care", "patient- and family-centered care" and "child" or "pediatric" or "pediatrics" or "child" or "newborn" or "neonatal" or "adolescent" together. The VOSviewer program was used for data analysis and visualization. The analysis included the number of publications by year, distribution by journals, most cited studies, countries with the highest publication output, most frequently used keywords, and co-authorship dimensions, presented with visual maps. RESULTS: A total of 2525 studies conducted from 1980 onwards were analyzed. The analysis revealed that the initial publications related to the subject emerged in 1980, and the United States was identified as the country with the highest number of publications, based on the Web of Science database. The Journal of Pediatric Nursing: Nursing Care of Children and Families (JPN) was determined as the journal with the highest number of publications, while the journal receiving the most citations was PEDIATRICS. CONCLUSION: The study found an increasing importance given to the Family-Centered Care Approach since the 1980s, with a majority of studies being descriptive in nature. It was determined that the studies were concentrated in the USA indicating a lack of global interest in the Family-Centered. PRACTICAL IMPLICATIONS: Nursing researchers can build upon this study in the field of family-centered care by conducting more specific and in-depth investigations. This contributes to adding new information to the nursing literature and filling gaps in this area.

The initial experiences of junior nursing college students when communicating with children during pediatric clinical practicum: A phenomenological study.

PURPOSE: Nursing students feel stressed during pediatric clinical practicum due to limited communication encounters with hospitalized children. The purpose of this study was to describe junior nursing college students' experiences of communicating with children during pediatric clinical practicums. DESIGN AND METHODS: A qualitative phenomenological research design was used. Purposive sampling was used to recruit 18 junior nursing college students who completed their pediatric clinical practicum. Data were collected using semi-structured interviews and were analyzed using Colaizzi's seven-step method for data analysis. RESULTS: Three themes emerged from the data. (1) Difficulties in communicating during initial practicum: fear, rejection, self-doubt of communication abilities, and unfamiliarity with the application of communication techniques posed frustrations among nursing students. (2) Efforts to learn during practicum: self-empowerment, seeking a diverse support system, adjusting communication methods, and striving to establish good relationships allowed nursing students to adapt to the pediatric curriculum. (3) Effective communication at the later stages of practicum: mastering fundamental communication techniques and exercising pediatric therapeutic communication techniques allowed nursing students to feel accomplished. CONCLUSIONS: Junior nursing college students initially encountered difficulties and frustration when communicating with children during their pediatric clinical practicum. This study serves as a guide for educators of pediatric nursing to design courses on communication with hospitalized children. PRACTICE IMPLICATIONS: These findings could be used to develop foundation courses on communicating with children for first-time pediatric nursing practicum students; for example, formulating a course on therapeutic play for children that encompasses communication techniques, pediatric ward simulation, and introduction to therapeutic play.

"Did I do the right thing?" Nurses' experiences of caring for victims of child maltreatment: A qualitative study.

PURPOSE: The purpose of this study is to explore and gain insight into pediatric nurses' lived experiences in caring for children who experienced maltreatment. DESIGN AND METHOD: A qualitative descriptive phenomenological approach using Giorgi's method was used to support the inquiry of this study. Participants were recruited through the Society of Pediatric Nurses (SPN) and the International Association of Forensic Nursing (IAFN). To collect data, the research team conducted semi-structured interviews individually with each participant online via online video conferencing. RESULTS: A total of 21 nurses participated in the study. In the final analysis of data, six meaning units are found: (1) helplessly watching children relive the traumatizing events, (2) lack of knowledge and training on caring for children who experienced maltreatment, (3) adversarial relationship and resentment towards parents, (4) conflicting emotions and feelings, (5) long-lasting effects of trauma, and (6) feelings of isolation and loneliness. CONCLUSIONS: Pediatric and forensic nurses' experiences of caring for children who experienced maltreatment were highlighted by the fact that they lacked the knowledge of caring for these children and felt isolated. PRACTICE IMPLICATIONS: Implementing simulation training on nurses' knowledge and confidence in caring for children who experienced maltreatment is a paramount of importance. This in turn may improve nurses' sense of belonging and enhance the quality of care victims receive.

An mHealth application for chronic vascular access: Consumer led co-creation.

PURPOSE: Children with chronic and complex health conditions frequently need intravenous devices. The current approach to intravenous device selection, insertion, and monitoring is inconsistent, and healthcare consumers are often negatively affected by siloed health information, and poor future planning. Despite child- and family-centred care being recognised as a pillar of paediatric nursing care, limited implementation for vascular access device planning and management is evident. DESIGN AND METHODS: To address this, we conducted a multi-phased approach to co-create, then evaluate, a mobile health (mHealth) application: IV Passport. Co-creation involved a prioritisation survey, followed by a Passport advisory panel consensus meeting. Following confirmation of the required content and features of the Passport, the mHealth application was designed and content validation achieved via survey. RESULTS: The prioritisation survey yielded recommendations for seven features (e.g., graphical presentations of current/past devices). Content for nine device types (e.g., totally implanted ports) was suggested, each with 10 related items (e.g., insertion site). Content items for device-associated complications, future vascular access plans, and educational resources were also suggested. Following design, the application was released through Apple and Android platforms; and adapted to a paper version. Content validation was established; 100% strongly agreed the application was easy to use; 80% agreed/strongly agreed that they would recommend the Passport to others. CONCLUSION: IV Passport embodies effective child- and family-centred care through consumer co-creation to empower patients and families manage vascular access devices. PRACTICE IMPLICATIONS: IV Passport remains active; and can be utilised across many healthcare settings and patient populations.

Developing and validating a 2D digital version of the Brazilian Children's anxiety questionnaire.

PURPOSE: This study aims to transpose the printed Brazilian Children's Anxiety Questionnaire (CAQ BR) into a 2D digital format, validate it with nurses and hospitalized children, and analyze the association between the printed and 2D digital format versions. DESIGN AND METHOD: This is a descriptive and multicentric study, conducted from 2021 to 2022 on working in pediatric care at two hospitals in Brazil. The nurses analyzed the printed and digital instruments and subsequently applied them to a child and proposed suggestions. A cutoff score of 0.80 on the content validity index was used; items that scored an average lower than the CVI in the study were adequate. Eighty children responded to the questionnaires sequentially according to the randomization table. A 90% agreement rate was used. RESULTS: The digital instrument was validated in content by 51 experts, with a CVI of 0.95. Face validation data for 80 children (mean age = 7.9 years) shows a 90% agreement rate. The intraclass correlation index for the general score was 0.87 and 95% CI (0.79-0.91), which shows good stability of the children's responses in both questionnaires. In addition, 59% (n = 47) of the children reported a preference for the digital questionnaire. CONCLUSIONS: The digital CAQ BR can be used as an audiovisual instrument by nurses when implementing the systematization of nursing care in pediatrics. PRACTICAL IMPLICATIONS: The digital 2D version was successfully applied and can be used in hospitals to measure children's self-reported anxiety.

Development and effectiveness of a metaverse reality-based family-centered handoff education program in nursing students.

PURPOSE: Effective patient handoffs are vital in pediatric populations. This study aimed to develop and identify the impact of a metaverse-based handoff program using ZEPETO on nursing students' handoff competence, handoff self-efficacy, learning realism, and satisfaction. DESIGN AND METHODS: This study used a non-randomized, pre-post nonequivalent group design to develop, implement, and verify a metaverse-based handoff simulation program in a nursing school in South Korea. We assigned 69 senior nursing students from a university to an experimental group or a control group. We developed a metaverse-based, handoff simulation program of family-centered care by building a pediatric intensive care unit (PICU) using ZEPETO. The program included an online lecture, a metaverse rounding discussion, and a metaverse-based handoff simulation of postoperative care for infants with congenital heart disease. We measured handoff competence, handoff self-efficacy, learning realism, and learning satisfaction pre- and post-program. RESULT(S): The experimental group showed significantly higher handoff self-efficacy than the control group (t = 3.17, p = 0.002). No significant differences were found in handoff competency, learning realism, or learning satisfaction between the groups. CONCLUSION(S): This study confirmed that a family-centered care-based handoff metaverse simulation program based on the experiential learning theory enhanced nursing students' handoff self-efficacy. The program equipped students to conduct safe and effective handoffs in real-world clinical settings by providing an immersive learning experience and emphasizing patient-centered communication. PRACTICAL IMPLICATIONS: Based on these results, family-centered, handoff education programs are recommended to be developed that focus on learning realism and learning satisfaction to enhance nursing students' handoff competence.

Developing a NAPNAP Research Agenda to Guide Future Research and Quality Improvement in Pediatrics: Process, Challenges, and Future Directions.

INTRODUCTION: This study aimed to develop a revised pediatric Research Agenda that highlights the clinical and research priorities for pediatric-focused advanced practice registered nurses and is culturally sensitive and inclusive. METHOD: The National Association of Pediatric Nurse Practitioners (NAPNAP) Research Committee developed the Research Agenda 2021-2026 by conducting a cross-sectional study that surveyed the membership on their research and clinical priorities in June 2020. Twenty-four priorities were identified within seven areas of focus. RESULTS: Among the 7,509 National Association of Pediatric Nurse Practitioners members, 273 (3.6%) responded to the email and 199 completed the survey. DISCUSSION: This revised Research Agenda is a bold and innovative guide for grant funding, publications, continuing education offerings, conference planning, and abstract submissions for posters and podium presentations aimed at improving pediatric health care. A discussion of the process and considerations for the future development of pediatric Research Agendas is described.