RESUMO
RATIONALE: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor of the lung, mostly presented in Asian middle-aged women. Initially, it was considered as a vascular origin tumor, but then research evidence showed that it was derived from natural epithelial tissue. On imaging, this tumor may be found as a solitary well-circumscribed lung parenchymal lesion, and is often located in juxtapleural or juxtafissural positions. On histopathology, it consists of cuboidal surface cells and stromal round cells, both of which are positive for thyroid transcription factor-1. Here we report a case of a young PSP male patient and review the relevant literature in order to improve our understanding of this disease. PATIENT CONCERNS: An 18-year-old man was referred to our hospital after accidentally finding a lesion on chest X-ray. Contrast-enhanced computed tomography showed a soft tissue mass with homogeneous enhancement in the left lower lobe posterior segment. DIAGNOSES: The diagnosis of PSPs was confirmed by histopathological examination. INTERVENTIONS AND OUTCOMES: The patient underwent a thoracoscopic wedge resection and was followed-up after that. One month later, he had good performance status with no recurrent tumors. LESSONS: PSP in a young man is really uncommon, and is confused with malignant tumors. A histopathological examination is considered as the diagnostic gold standard for this uncommon tumor. Surgery is the main treatment.
Assuntos
Hemangioma Esclerosante Pulmonar/diagnóstico , Adolescente , Biópsia com Agulha de Grande Calibre/métodos , Humanos , Masculino , Hemangioma Esclerosante Pulmonar/fisiopatologia , Radiografia/métodos , Tomografia Computadorizada por Raios X/métodosAssuntos
Dor no Peito , Hemoptise , Pneumonectomia/métodos , Hemangioma Esclerosante Pulmonar , Tomografia Computadorizada por Raios X/métodos , Adulto , Anti-Inflamatórios/uso terapêutico , Dor no Peito/diagnóstico , Dor no Peito/etiologia , Dor no Peito/fisiopatologia , Diagnóstico Diferencial , Resistência a Medicamentos , Feminino , Hemoptise/diagnóstico , Hemoptise/etiologia , Hemoptise/fisiopatologia , Hemostáticos/uso terapêutico , Humanos , Pulmão/diagnóstico por imagem , Pulmão/patologia , Pulmão/cirurgia , Hemangioma Esclerosante Pulmonar/diagnóstico , Hemangioma Esclerosante Pulmonar/fisiopatologia , Hemangioma Esclerosante Pulmonar/cirurgia , Recuperação de Função Fisiológica , Resultado do TratamentoRESUMO
PURPOSE: Pulmonary sclerosing hemangioma (PSH), or the alternative name of "sclerosing pneumocytoma," is a rare benign neoplasm. PSH is often asymptomatic and presents as a solitary pulmonary nodule on radiologic imaging studies. Few articles have been reported to describe the FDG PET findings about PSH. We reported FDG PET findings of 6 cases of PSH and reviewed the literatures. MATERIALS AND METHODS: FDG PET and PET/CT imaging studies of 6 patients with proven PSH were reviewed. The relation between the degree of FDG uptake and tumor size was analyzed. RESULTS: All 6 tumors were detected by FDG PET or PET/CT. Mean diameter of these tumors was 2.9 cm. Mean standard uptake value was 2.45 (range, 1.8-3.93). The maximal standard uptake value of FDG uptake was positively correlated with the tumor size (R = 0.9694, P < 0.05). CONCLUSIONS: PSH demonstrates low to moderate uptake on FDG PET imaging. The larger PSH has higher uptake and might be misrecognized as a malignancy. The possibility of false-positive result caused by PSH should be considered while interpreting FDG PET images of solitary pulmonary nodules.
Assuntos
Fluordesoxiglucose F18 , Tomografia por Emissão de Pósitrons , Hemangioma Esclerosante Pulmonar/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Hemangioma Esclerosante Pulmonar/patologia , Hemangioma Esclerosante Pulmonar/fisiopatologia , Estudos RetrospectivosRESUMO
We present a 53-year-old female suffering from familial adenomatous polyposis, who was found to have a positive nodus, lateral to the hilus of the left lung, on routine FDG-PET scan. This lesion was found to be a sclerosing hemangioma. We found an aberrant beta-catenin expression on immunohistochemical staining, suggesting that sclerosing hemangioma and familial adenomatous polyposis share the same pathophysiology. It is important to be aware of the association of familial adenomatous polyposis and sclerosing hemangioma.