RESUMO
Purpose: To firstly present management of toxic anterior segment syndrome (TASS) and possible postoperative endophthalmitis (POE) after implantation of a new hydrophilic-acrylic posterior chamber (PC) phakic intraocular lens (pIOL) in a case with undeclared history of COVID-19.Methods: A 21-year-old male without known disease represented severe anterior chamber inflammation (hypopyon), poor vision and corneal edema without vitreous involvement (TASS) at 24-hours after PC-pIOL implantation for unilateral high myopia (amblyopic).Results: Preoperative best-corrected visual acuity (BCVA) was 0.2 OS (-13 diopters). At 56-hours, vitreous was involved with visual loss indicating POE. The patient confessed that he had COVID-19 1-month ago. COVID-19 immunoglobulin M/G tests were positive, while other markers were negative. Intracameral/intravitreal antibiotics were applied. BCVA was 0.15 without hypopyon at 24-hours. Cultures were negative. Final BCVA was 0.6 with normal examination.Conclusion: TASS/POE etiology could not be demonstrated in this case, whereas COVID-19-related proinflammatory systemic background could have effect on triggering/aggravating this scenario.].
Assuntos
COVID-19/epidemiologia , Endoftalmite/etiologia , Infecções Oculares Virais/etiologia , Miopia/cirurgia , Lentes Intraoculares Fácicas/efeitos adversos , SARS-CoV-2/genética , Infecção da Ferida Cirúrgica/etiologia , Segmento Anterior do Olho/diagnóstico por imagem , Segmento Anterior do Olho/virologia , Comorbidade , Endoftalmite/diagnóstico , Endoftalmite/virologia , Infecções Oculares Virais/diagnóstico , Infecções Oculares Virais/virologia , Humanos , Implante de Lente Intraocular , Masculino , Miopia/epidemiologia , RNA Viral/análise , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/virologia , Adulto JovemRESUMO
Cytomegalovirus (CMV)-related corneal endotheliitis is an inflammation of the corneal endothelium caused by CMV. It may occur de novo or after ocular surgery in otherwise healthy individuals. In patients who have undergone keratoplasty, the differential diagnosis of viral endotheliitis and immune-related graft rejection is challenging due to the similar clinical findings. Here we report a patient who underwent penetrating keratoplasty and was using local and systemic immunosuppressive agents due to previous history of graft rejection. At postoperative year 4, ophthalmologic examination revealed localized corneal edema, coin-shaped keratic precipitates, and increased intraocular pressure, consistent with viral endotheliitis. Polymerase chain reaction revealed CMV-DNA amplification in the aqueous humor sample. Valganciclovir treatment was started and the symptoms improved in 2 months. It should be kept in mind that local or systemic immunosuppressants used after keratoplasty may trigger CMV reactivation. Anti-CMV treatment should be initiated immediately in patients with coin-shaped keratic precipitates.
Assuntos
Infecções por Citomegalovirus/diagnóstico , Endotélio Corneano/patologia , Infecções Oculares Virais/diagnóstico , Ceratite/diagnóstico , Ceratoplastia Penetrante/efeitos adversos , Infecção da Ferida Cirúrgica/diagnóstico , Adulto , Citomegalovirus/genética , Infecções por Citomegalovirus/virologia , DNA Viral/análise , Endotélio Corneano/virologia , Infecções Oculares Virais/virologia , Humanos , Ceratite/virologia , Masculino , Infecção da Ferida Cirúrgica/virologiaAssuntos
Infecções por Citomegalovirus/etiologia , Citomegalovirus/genética , Ceratoplastia Endotelial com Remoção da Lâmina Limitante Posterior/efeitos adversos , Endoftalmite/etiologia , Endotélio Corneano/patologia , Infecções Oculares Virais/etiologia , Infecção da Ferida Cirúrgica/etiologia , Idoso de 80 Anos ou mais , Doenças da Córnea/cirurgia , Infecções por Citomegalovirus/diagnóstico , Infecções por Citomegalovirus/virologia , DNA Viral/análise , Endoftalmite/diagnóstico , Endoftalmite/virologia , Endotélio Corneano/virologia , Infecções Oculares Virais/diagnóstico , Infecções Oculares Virais/virologia , Feminino , Humanos , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/virologiaAssuntos
Infecções Oculares Virais/diagnóstico , Herpes Zoster/diagnóstico , Herpesvirus Humano 3 , Hospedeiro Imunocomprometido , Infecção da Ferida Cirúrgica/diagnóstico , Adulto , Infecções Oculares Virais/virologia , Feminino , Herpes Zoster/virologia , Humanos , Doenças Raras , Infecção da Ferida Cirúrgica/virologiaRESUMO
OBJECTIVES: Recurrent respiratory papillomatosis is often treated with in-office laser procedures using a potassium titanyl phosphate (KTP) laser transmitted through a laser fiber. Although effective, this procedure has notable downsides, including the possibility of transmitting human papillomavirus (HPV) in the smoke plume and the high cost of these single-use fibers. The objective of this study is to determine if HPV can be detected on a laser fiber after use, with or without sterilization. METHODS: Twelve patients with laryngeal papillomas were treated with KTP laser energy transmitted via a KTP fiber. Ten fibers were sterilized in CIDEX (ASP, Irvine, California), a glutaraldehyde disinfectant, for 12 minutes, whereas two fibers were left unsterilized. Human papillomavirus DNA amplification was done on all 12 fiber samples with real-time polymerase chain reaction (PCR) using general primer mediated 5+ and 6+. Human papillomavirus genotyping detection was done using type specific probes and/or Sanger sequencing. RESULTS: Over 27 strains of HPV were not detected on KTP fibers after use, with or without sterilization. CONCLUSION: Human papillomavirus was undetectable by PCR on KTP laser fibers that were sterilized or unsterilized after use. Further studies are needed utilizing a transmission model to determine if HPV can be incubated from this fiber after sterilization. LEVEL OF EVIDENCE: NA. Laryngoscope, 128:926-928, 2018.
Assuntos
DNA Viral/genética , Contaminação de Equipamentos/estatística & dados numéricos , Neoplasias Laríngeas/cirurgia , Lasers de Estado Sólido/efeitos adversos , Papillomaviridae/genética , Infecções por Papillomavirus/virologia , Infecções Respiratórias/virologia , Infecção da Ferida Cirúrgica/virologia , California/epidemiologia , Feminino , Humanos , Incidência , Terapia a Laser/instrumentação , Masculino , Papiloma/cirurgia , Infecções por Papillomavirus/diagnóstico , Infecções por Papillomavirus/epidemiologia , Reação em Cadeia da Polimerase , Infecções Respiratórias/diagnóstico , Infecções Respiratórias/epidemiologia , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/epidemiologiaRESUMO
PURPOSE: To report a case of bilateral varicella zoster virus (VZV)-associated acute retinal necrosis (ARN) occurring after both eyes sequential cataract surgery in an elderly immunocompromised patient. METHODS: Medical records and investigation results of the patient were reviewed. RESULTS: Patient experienced floaters and blurring of vision in both eyes 4 weeks after her second uncomplicated cataract surgery. Clinical signs of granulomatous keratic precipitates, prominent vitritis, retinitis and vascular thrombosis were noted in both eyes. Aqueous samples from both eyes were positive for VZV. Disease was treated with intravitreal foscarnet bilaterally and 10 days of systemic intravenous acyclovir (10 mg/kg) followed by oral valaciclovir 1 g three times daily. Final visual acuity at 4 months after initial presentation was 20/60 in both eyes with no retinal detachment noted. CONCLUSIONS: Cataract surgery may have been the trigger for bilateral VZV-associated ARN. Immunocompromised patients can develop ARN and require close observation after cataract surgery. This is, to our knowledge, the first report of bilateral ARN following routine cataract surgery.
Assuntos
Extração de Catarata/efeitos adversos , Infecções Oculares Virais/etiologia , Herpesvirus Humano 3/imunologia , Hospedeiro Imunocomprometido , Síndrome de Necrose Retiniana Aguda/etiologia , Infecção da Ferida Cirúrgica/etiologia , Infecção pelo Vírus da Varicela-Zoster/etiologia , Idoso , Anticorpos Antivirais/imunologia , Infecções Oculares Virais/virologia , Feminino , Humanos , Síndrome de Necrose Retiniana Aguda/imunologia , Síndrome de Necrose Retiniana Aguda/virologia , Infecção da Ferida Cirúrgica/imunologia , Infecção da Ferida Cirúrgica/virologia , Infecção pelo Vírus da Varicela-Zoster/diagnóstico , Infecção pelo Vírus da Varicela-Zoster/virologia , Acuidade VisualAssuntos
Carcinoma de Células Escamosas/cirurgia , Retalhos de Tecido Biológico , Neoplasias Bucais/cirurgia , Estomatite Herpética/diagnóstico , Estomatite Herpética/virologia , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/virologia , Idoso , Diagnóstico Diferencial , Glossectomia , Humanos , Masculino , Escápula/transplanteAssuntos
Carcinoma Basocelular/cirurgia , Neoplasias Faciais/cirurgia , Herpes Zoster/diagnóstico , Hospedeiro Imunocomprometido , Cirurgia de Mohs , Infecção da Ferida Cirúrgica/virologia , Idoso de 80 Anos ou mais , Antivirais/uso terapêutico , Testa , Herpes Zoster/tratamento farmacológico , Humanos , Masculino , Manejo da Dor , Medição da DorRESUMO
Surgical site infections (SSIs) are infections of tissues, organs, or spaces exposed by surgeons during performance of an invasive procedure. SSIs are classified into superficial, which are limited to skin and subcutaneous tissues, and deep. The incidence of deep SSIs in lung transplant (LTx) patients is estimated at 5%. No reports have been published as to the incidence of superficial SSIs specifically in LTx patients. Common sense would dictate that the majority of superficial SSIs would be bacterial. Uncommonly, fungal SSIs may occur, and we believe that no reports exist as to the incidence of viral wound infections in LTx patients, or in any solid organ transplant patients. We report a de novo superficial wound infection with herpes simplex virus following lung transplantation, its possible source, treatment, and resolution.
Assuntos
Antivirais/uso terapêutico , Ganciclovir/uso terapêutico , Herpes Simples/diagnóstico , Transplante de Pulmão/efeitos adversos , Simplexvirus/isolamento & purificação , Infecção da Ferida Cirúrgica/diagnóstico , Adolescente , Feminino , Herpes Simples/tratamento farmacológico , Herpes Simples/etiologia , Herpes Simples/virologia , Humanos , Infecção da Ferida Cirúrgica/tratamento farmacológico , Infecção da Ferida Cirúrgica/etiologia , Infecção da Ferida Cirúrgica/virologia , Resultado do TratamentoRESUMO
In general surgery the etiology of surgical site infections has not significantly changed over the last 30 years. Gram-positive bacteria, e.g. coagulase negative staphylococci (CNS), Staphylococcus aureus and Enterococcus spp. as well as Gram-negative bacteria, e.g. Escherichia coli, Enterobacter spp., Klebsiella spp. and Pseudomonas aeruginosa, are the most common findings. Although in general surgery 10% of the S. aureus causing postoperative wound infections were methicillin resistant (MRSA), no cases of multidrug-resistant Gram-negative (MRGN) bacteria were reported. Yeasts (particularly Candida spp.) are rarely the pathogen causing surgical site infections (≤3%) and concomitant risk factors are typical (e.g. diabetes, chemotherapy, immunosuppression and malnutrition). Viruses are rarely the cause of surgical site infections. Transmission can occur by HBV, HCV or HIV positive surgical staff or in organ transplantations and postoperative reactivation of persistent infections is possible (especially for HBV, HCV, CMV, EBV and HIV). The principles for prevention of surgical site infections are dealt with as consequences of preoperative colonization by MRSA, methicillin-sensitive S. aureus (MSSA) and MRGN and reviewed with respect to screening, perioperative antibiotic prophylaxis and decolonization. In nosocomial peritonitis, the selection of antibiotics should consider previous antibiotic treatment. A single intra-abdominal detection of Candida spp. usually does not require antimycotic treatment in postoperatively stable and immunocompetent patients but is recommended in severe community-acquired or nosocomial peritonitis. Viral infections can be avoided by screening of organ donors and serological surveillance of surgery personnel.
Assuntos
Infecções Bacterianas/microbiologia , Farmacorresistência Bacteriana Múltipla , Infecção da Ferida Cirúrgica/microbiologia , Antibioticoprofilaxia , Infecções Bacterianas/prevenção & controle , Infecções Bacterianas/transmissão , Candidíase/microbiologia , Candidíase/prevenção & controle , Candidíase/transmissão , Cirurgia Geral , Humanos , Staphylococcus aureus Resistente à Meticilina , Fatores de Risco , Infecção da Ferida Cirúrgica/prevenção & controle , Infecção da Ferida Cirúrgica/transmissão , Infecção da Ferida Cirúrgica/virologia , Enterococos Resistentes à Vancomicina , Viroses/prevenção & controle , Viroses/transmissão , Viroses/virologiaRESUMO
Postoperative infection after elective arthrodesis of the interphalangeal joint is an uncommon complication often necessitating urgent debridement. We present the rare case of a female patient with a history of oral herpetic lesions, who underwent elective arthrodesis of the middle and index fingers for treatment of erosive osteoarthritis and subsequently developed a postoperative herpetic infection at the surgical site.
Assuntos
Artrodese , Articulações dos Dedos/cirurgia , Herpes Simples/diagnóstico , Herpes Simples/cirurgia , Osteoartrite/cirurgia , Infecção da Ferida Cirúrgica/cirurgia , Infecção da Ferida Cirúrgica/virologia , Desbridamento , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
We report a case of an extremely preterm infant with intestinal malrotation who contracted postnatal systemic cytomegalovirus (CMV) infection with a complicated intestinal evolution requiring repeated surgical interventions and antiviral treatment. This report is to emphasize that prolonged gastrointestinal symptoms in extremely preterm infants fed with non-pasteurized breast milk should lead to suspicion of CMV infection. The importance of preventive measures when feeding very preterm infants with breast milk needs to be considered. Furthermore, the indications for antiviral treatment, in particular in preterm infants, need to be clarified.
Assuntos
Aleitamento Materno/efeitos adversos , Infecções por Citomegalovirus/etiologia , Anormalidades do Sistema Digestório/cirurgia , Doenças do Prematuro , Transmissão Vertical de Doenças Infecciosas , Volvo Intestinal/cirurgia , Leite Humano/virologia , Infecção da Ferida Cirúrgica/etiologia , Citomegalovirus/genética , Infecções por Citomegalovirus/virologia , DNA Viral/análise , Procedimentos Cirúrgicos do Sistema Digestório/efeitos adversos , Idade Gestacional , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Masculino , Infecção da Ferida Cirúrgica/virologiaRESUMO
The survival rate following lung transplantation is among the lowest of all solid-organ transplants, and current diagnostic tests often fail to distinguish between infection and rejection, the two primary posttransplant clinical complications. We describe a diagnostic assay that simultaneously monitors for rejection and infection in lung transplant recipients by sequencing of cell-free DNA (cfDNA) in plasma. We determined that the levels of donor-derived cfDNA directly correlate with the results of invasive tests of rejection (area under the curve 0.9). We also analyzed the nonhuman cfDNA as a hypothesis-free approach to test for infections. Cytomegalovirus is most frequently assayed clinically, and the levels of CMV-derived sequences in cfDNA are consistent with clinical results. We furthermore show that hypothesis-free monitoring for pathogens using cfDNA reveals undiagnosed cases of infection, and that certain infectious pathogens such as human herpesvirus (HHV) 6, HHV-7, and adenovirus, which are not often tested clinically, occur with high frequency in this cohort.
Assuntos
DNA Viral/sangue , Rejeição de Enxerto/diagnóstico , Transplante de Pulmão/efeitos adversos , Cuidados Pós-Operatórios/métodos , Infecção da Ferida Cirúrgica/diagnóstico , Sequência de Bases , Citomegalovirus/genética , Humanos , Dados de Sequência Molecular , Polimorfismo de Nucleotídeo Único/genética , Análise de Sequência de DNA , Especificidade da Espécie , Infecção da Ferida Cirúrgica/virologiaRESUMO
Although originally described in Staphylococcus aureus, resistance among bacteria has now become a race to determine which classes of bacteria will become more resistant. Availability of antibacterial agents has allowed the development of entirely new diseases caused by nonbacterial pathogens, related largely to fungi that are inherently resistant to antibacterials. This article presents the growing body of knowledge of the herpes family of viruses, and their occurrence and consequences in patients with concomitant surgical disease or critical illness. The focus is on previously immunocompetent patients, as the impact of herpes viruses in immunosuppressed patients has received thorough coverage elsewhere.
Assuntos
Infecção Hospitalar/microbiologia , Resistência Microbiana a Medicamentos , Infecção da Ferida Cirúrgica/microbiologia , Antivirais/uso terapêutico , Candidíase/etiologia , Candidíase/microbiologia , Candidíase/terapia , Infecção Hospitalar/terapia , Infecção Hospitalar/virologia , Infecções por Herpesviridae/diagnóstico , Infecções por Herpesviridae/tratamento farmacológico , Infecções por Herpesviridae/etiologia , Infecções por Herpesviridae/microbiologia , Humanos , Staphylococcus aureus Resistente à Meticilina , Fatores de Risco , Infecções Estafilocócicas/etiologia , Infecções Estafilocócicas/microbiologia , Infecções Estafilocócicas/terapia , Infecção da Ferida Cirúrgica/terapia , Infecção da Ferida Cirúrgica/virologia , Enterococos Resistentes à VancomicinaRESUMO
PURPOSE: Cytomegalovirus (CMV) infection is known to be the most frequently viral infection among patients after liver transplantation. This is especially true in pediatric living-donor liver transplantation because the recipients have often not been infected with CMV and postoperative primary infection with CMV frequently occurs. PATIENTS AND METHODS: Of 93 patients who underwent pediatric liver transplantation at our department, 33 patients (36.3%) were diagnosed with CMV infection using the antigenemia method (C7-HRP). Retrospective review and statistical analysis were conducted to confirm risk factors of post-transplantation CMV infection. RESULT: Positive lymphocytes were diagnosed between postoperative days 8 and 111 after transplantation. Ganciclovir or foscavir were administrated to 21 patients. The other 10 patients who had one positive lymphocyte were observed and the cell disappeared on follow-up examination. We did not observe any cases of positive lymphocytes with C7-HRP in patients who received a graft from a CMV antibody-negative donor. Independent predictors associated with CMV infection in the multivariable analysis were administration of OKT3 and grafts from CMV antibody-positive donors. CONCLUSION: In CMV infection after pediatric liver transplantation, cases with CMV antibody-positive donors and with OKT3 administration for acute rejection are considered high risk, and cases with CMV antibody-negative donors are considered low risk.
Assuntos
Infecções por Citomegalovirus/epidemiologia , Transplante de Fígado/efeitos adversos , Infecção da Ferida Cirúrgica/epidemiologia , Doadores de Tecidos , Adulto , Anticorpos Antivirais/análise , Criança , Pré-Escolar , Citomegalovirus/imunologia , Infecções por Citomegalovirus/diagnóstico , Infecções por Citomegalovirus/virologia , Feminino , Humanos , Incidência , Lactente , Japão/epidemiologia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/virologia , Adulto JovemRESUMO
The role of surgical gloving is to minimise the risk of surgical site infection (SSI) and to protect the surgical team from cross infection. However, different practitioners have different views as to when double gloving is appropriate, with many factors like speciality and procedure dictating their use. This review will look at best practice through the evidence available and provide recommendations for practice.
Assuntos
Infecção Hospitalar/prevenção & controle , Luvas Cirúrgicas , Procedimentos Cirúrgicos Operatórios/enfermagem , Infecção da Ferida Cirúrgica/prevenção & controle , Infecções Bacterianas/prevenção & controle , Infecção Hospitalar/microbiologia , Infecção Hospitalar/virologia , Humanos , Procedimentos Cirúrgicos Operatórios/efeitos adversos , Infecção da Ferida Cirúrgica/microbiologia , Infecção da Ferida Cirúrgica/virologia , Viroses/prevenção & controleRESUMO
PURPOSE: To report a case of recurrent cytomegalovirus (CMV) corneal endotheliitis after penetrating keratoplasty. METHODS: Penetrating keratoplasty (PK) was performed in a 49-year-old man with bullous keratopathy. Pigmented keratic precipitates (KPs) were found in the corneal endothelium of the graft 13 days after surgery, with the subsequent appearance of coin-shaped lesions. Confocal microscopy was performed on the corneal endothelium. Aqueous humor was analyzed for viral DNA by polymerase chain reaction (PCR). RESULTS: CMV DNA was detected from the excised corneal button, and aqueous humor revealed positive results for CMV and HSV1 by PCR. Confocal microscopy showed large corneal endothelial cells, consistent with the typical owl's eye morphology of CMV endotheliitis. After systemic ganciclovir was administered, the pigmented KPs and coin-shaped lesions gradually decreased. CONCLUSIONS: Stress from surgery and corticosteroid usage can revitalize CMV activity. PCR and confocal microscopy are valuable for the diagnosis of CMV corneal endotheliitis.
Assuntos
Infecções por Citomegalovirus/etiologia , Citomegalovirus/genética , Endotélio Corneano/patologia , Infecções Oculares Virais/etiologia , Ceratite/etiologia , Ceratoplastia Penetrante/efeitos adversos , Infecção da Ferida Cirúrgica/etiologia , Humor Aquoso/virologia , Infecções por Citomegalovirus/diagnóstico , Infecções por Citomegalovirus/virologia , DNA Viral/análise , Diagnóstico Diferencial , Endotélio Corneano/virologia , Infecções Oculares Virais/diagnóstico , Infecções Oculares Virais/virologia , Humanos , Ceratite/diagnóstico , Ceratite/virologia , Masculino , Pessoa de Meia-Idade , Reação em Cadeia da Polimerase , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/virologia , Tomografia de Coerência ÓpticaRESUMO
Intestine transplant is indicated for patients with intestinal failure who are unable to be weaned from parenteral nutrition (PN). Long-term PN, although life sustaining in many patients, can be associated with life-threatening complications including PN-associated liver disease (PNALD). Most patients are not considered for intestine transplant until they have developed severe PNALD and also need a liver transplant. Overall outcomes with intestinal transplantation are steadily improving, and current 1-year patient survivals for intestine-only transplants are now similar to those for liver transplant. Intestinal transplantation should be considered earlier in intestinal failure patients who are at high risk for developing PNALD and other life-threatening complications.
Assuntos
Enteropatias/cirurgia , Intestinos/transplante , Contraindicações , Seleção do Doador , Rejeição de Enxerto/diagnóstico , Rejeição de Enxerto/etiologia , Rejeição de Enxerto/terapia , Sobrevivência de Enxerto , Humanos , Enteropatias/epidemiologia , Enteropatias/fisiopatologia , Intestinos/fisiopatologia , Doadores Vivos , Transplante de Órgãos/tendências , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/microbiologia , Infecção da Ferida Cirúrgica/terapia , Infecção da Ferida Cirúrgica/virologiaRESUMO
OBJECTIVE: This study was designed to determine the prevalence of complications associated with abdominal delivery in a setting of high caesarean section (C/S) and HIV rates. METHOD: A detailed review of the records of 737 C/S performed over a three-month period was conducted in a tertiary teaching hospital in Durban, South Africa. RESULTS: The overall complication rate was 14.2%. Major complications included endometritis, wound sepsis, post-partum haemorrhage and bladder injury. HIV infection may have a negative impact on morbidity rates. Disimpacting the fetal head vaginally had a significant association with endometritis (p=0.021). The use of a corrugated drain did not prevent wound sepsis (p<0.001). CONCLUSION: Complications associated with C/S are common is a setting of high C/S rates and HIV infection.
Assuntos
Cesárea/efeitos adversos , Infecções por HIV/complicações , Infecções por HIV/epidemiologia , Complicações Pós-Operatórias/epidemiologia , Infecções Oportunistas Relacionadas com a AIDS/etiologia , Infecções Oportunistas Relacionadas com a AIDS/microbiologia , Infecções Oportunistas Relacionadas com a AIDS/virologia , Adulto , Endometrite/etiologia , Endometrite/microbiologia , Endometrite/virologia , Feminino , Hemostasia , Humanos , Gravidez , Complicações Infecciosas na Gravidez/epidemiologia , Complicações Infecciosas na Gravidez/etiologia , Prevalência , Estudos Retrospectivos , África do Sul/epidemiologia , Infecção da Ferida Cirúrgica/etiologia , Infecção da Ferida Cirúrgica/microbiologia , Infecção da Ferida Cirúrgica/virologia , Bexiga Urinária/lesõesRESUMO
PURPOSE: To report two cases of herpes simplex keratitis following excimer laser application. METHODS: Two immunocompetent patients with no history of ocular viral infection developed ulcers after LASIK and phototherapeutic keratectomy (PTK), respectively. RESULTS: Antiviral treatment was administered, and the lesions healed within 14 days. CONCLUSIONS: These two cases suggest that herpes simplex virus was associated with the use of the excimer laser.