RESUMO
We report the recent epidemiology and estimated seroprevalence of human hantavirus infections in the Netherlands. Sixty-two cases were reported during December 2008-December 2013. The estimated seroprevalence in the screened municipalities in 2006-2007 was 1.7% (95% CI 1.3%-2.3%). Findings suggest that hantavirus infections are underdiagnosed in the Netherlands.
Assuntos
Infecções por Hantavirus/epidemiologia , Infecções por Hantavirus/virologia , Orthohantavírus , Adolescente , Adulto , Idoso , Anticorpos Antivirais/sangue , Anticorpos Antivirais/imunologia , Feminino , Geografia Médica , Orthohantavírus/classificação , Orthohantavírus/imunologia , Infecções por Hantavirus/história , História do Século XXI , Humanos , Masculino , Pessoa de Meia-Idade , Países Baixos/epidemiologia , Vigilância em Saúde Pública , Estudos Soroepidemiológicos , Sorotipagem , Adulto JovemRESUMO
In summer 2012, an outbreak of hantavirus infections occurred among overnight visitors to Yosemite National Park in California, USA. An investigation encompassing clinical, epidemiologic, laboratory, and environmental factors identified 10 cases among residents of 3 states. Eight case-patients experienced hantavirus pulmonary syndrome, of whom 5 required intensive care with ventilatory support and 3 died. Staying overnight in a signature tent cabin (9 case-patients) was significantly associated with becoming infected with hantavirus (p<0.001). Rodent nests and tunnels were observed in the foam insulation of the cabin walls. Rodent trapping in the implicated area resulted in high trap success rate (51%), and antibodies reactive to Sin Nombre virus were detected in 10 (14%) of 73 captured deer mice. All signature tent cabins were closed and subsequently dismantled. Continuous public awareness and rodent control and exclusion are key measures in minimizing the risk for hantavirus infection in areas inhabited by deer mice.
Assuntos
Infecções por Hantavirus/epidemiologia , Orthohantavírus/classificação , Viagem , Adolescente , Adulto , California/epidemiologia , Criança , Surtos de Doenças , Monitoramento Ambiental , Orthohantavírus/genética , Infecções por Hantavirus/diagnóstico , Infecções por Hantavirus/história , Infecções por Hantavirus/prevenção & controle , História do Século XXI , Humanos , Pessoa de Meia-Idade , Fatores de Risco , Sorotipagem , Adulto JovemRESUMO
The English sweating sickness caused five devastating epidemics between 1485 and 1551, England was hit hardest, but on one occasion also mainland Europe, with mortality rates between 30% and 50%. The Picardy sweat emerged about 150 years after the English sweat disappeared, in 1718, in France. It caused 196 localized outbreaks and apparently in its turn disappeared in 1861. Both diseases have been the subject of numerous attempts to define their origin, but so far all efforts were in vain. Although both diseases occurred in different time frames and were geographically not overlapping, a common denominator could be what we know today as hantavirus infections. This review aims to shed light on the characteristics of both diseases from contemporary as well as current knowledge and suggests hantavirus infection as the most likely cause for the English sweating sickness as well as for the Picardy sweat.
Assuntos
Surtos de Doenças/história , Infecções por Hantavirus/história , Infecções por Hantavirus/virologia , Orthohantavírus/isolamento & purificação , Doença do Suor/história , Doença do Suor/virologia , Inglaterra/epidemiologia , França/epidemiologia , Infecções por Hantavirus/epidemiologia , História do Século XVI , História do Século XVII , História Medieval , Humanos , Doença do Suor/epidemiologiaRESUMO
In Europe, hantavirus disease or hemorrhagic fever with renal syndrome is an endemic zoonosis that affects tens of thousands of individuals each year. The causative agents are viruses of the genus Hantavirus, family Bunyaviridae, rodents and insectivores act as carriers. In all European countries there is a seroprevalence for hantaviruses in the general population but not all countries report cases. Here, we give an overview of the hantavirus situation in Europe.