1.
Appl Biochem Biotechnol
; 14(2): 101-6, 1987 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3619437
RESUMO
The ammonium sulfate-precipitated fraction from mycelia and culture-filtrates and the crude, cell-free culture filtrates from the growth medium of the fungi Chrysosporium palmorum, Eurotium rubrum, Micromucor isabellina, and Pythium aphanidermatum when aseptically added to cell suspensions of Cantharanthus roseus caused a rapid and dramatic increase in indole alkaloid biosynthesis. Up to 400 micrograms/L ajmalicine and 600 micrograms/L catharanthine were detected in C. roseus cell suspension grown in the presence of the M. isabellina fungal culture filtrate for 3 d. Untreated cells produced only trace levels of ajmalicine and catharanthine per liter of cell suspension after 15 d of culture.
Assuntos
Fungos/fisiologia , Desenvolvimento Vegetal , Alcaloides de Triptamina e Secologanina , Alcaloides de Vinca/biossíntese , Ioimbina/biossíntese , Linhagem Celular , Isomerismo
2.
FEBS Lett
; 70(1): 267-70, 1976 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11128
3.
J Am Chem Soc
; 97(23): 6906-8, 1975 Nov 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-1184890
4.
Lloydia
; 37(2): 219-98, 1974 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4605222