RESUMO
INTRODUCTION: Benign neoplasm of the endobronchial tree is quite rare, while endobronchial lipoma is extremely rare. Tracheobronchial aspergillosis is a relatively uncommon but severe form of invasive aspergillosis involving the tracheobronchial tree. PATIENT CONCERNS: A 54-year-old male presented to our hospital for investigation and treatment of a cough and hemoptysis. DIAGNOSIS: The diagnosis was confirmed as endobronchial lipoma with tracheobronchial aspergillosis. INTERVENTIONS: The patient received pneumonectomy and voriconazole treatment. OUTCOMES: The patient's postoperative course was uneventful, and he was discharged 10âdays after surgery. The patient had no evidence of the fungal infection and recurrence during 1âyear of follow-up. CONCLUSION: Endobronchial lipoma is a rare benign lung tumor, and this is the first report of endobronchial lipoma with tracheobronchial aspergillosis. In patients with suspected endobronchial lipoma, especially those who present with hemoptysis as the initial symptom, it is advisable to exclude coexistent aspergillosis.
Assuntos
Aspergillus , Neoplasias Brônquicas/microbiologia , Lipoma/microbiologia , Aspergilose Pulmonar/complicações , Brônquios/microbiologia , Humanos , Masculino , Pessoa de Meia-Idade , Traqueia/microbiologiaRESUMO
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Assuntos
Lipoma/complicações , Abscesso Hepático/diagnóstico por imagem , Abscesso Hepático/etiologia , Neoplasias Gástricas/complicações , Ultrassonografia/métodos , Abscesso/complicações , Idoso , Drenagem , Feminino , Humanos , Lipoma/microbiologia , Abscesso Hepático/terapia , Tomografia Computadorizada por Raios X/métodosRESUMO
Adenovirus type 9 was inoculated sc into newborn Wistar/Furth rats, divided into four groups: (1) six male rats, not treated further; (2) 11 male rats, castrated at 4 weeks of age; (3) 12 male rats, castrated at 4 weeks of age and subsequently treated repeatedly with estrogen; and (4) 12 female rats, not treated further. All of the rats in group 3 developed mammary hyperplasia and tumors (fibroadenomas and lipomas), in some cases with malignant histologic structure. Rats in group 4 developed similar mammary tumors, but with later appearance and significantly slower growth. A fifth group of rats, not virus inoculated but castrated and estrogen treated as in group 3, did not develop any demonstrable mammary lesions. The results show that the effects of the virus on the mammary gland are dependent upon an estrogenic background, which by itself cannot cause tumor development in males. It is suggested that viral DNA is incorporated into the cellular DNA in such a way that it influences the synthesis and/or activity of steroid receptors, triggering tumor development.
