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1.
PLoS One ; 15(12): e0235024, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33264298

RESUMO

The objective of this work is to provide a mathematical analysis on how a Thoroughbred horse should regulate its speed over the course of a race to optimize performance. Because Thoroughbred horses are not capable of running the whole race at top speed, determining what pace to set and when to unleash the burst of speed is essential. Our model relies on mechanics, energetics (both aerobic and anaerobic) and motor control. It is a system of coupled ordinary differential equations on the velocity, the propulsive force and the anaerobic energy, that leads to an optimal control problem that we solve. In order to identify the parameters meaningful for Thoroughbred horses, we use velocity data on races in Chantilly (France) provided by France Galop, the French governing body of flat horse racing in France. Our numerical simulations of performance optimization then provide the optimal speed along the race, the oxygen uptake evolution in a race, as well as the energy or the propulsive force. It also predicts how the horse has to change its effort and velocity according to the topography (altitude and bending) of the track.


Assuntos
Cavalos/fisiologia , Corrida/fisiologia , Algoritmos , Altitude , Anaerobiose , Animais , Comportamento Competitivo , Consumo de Oxigênio , Condicionamento Físico Animal/fisiologia , Medicina Veterinária Esportiva/métodos
2.
Reprod Fertil Dev ; 31(12): 1917-1925, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31656221

RESUMO

Embryo biopsy for fetal sexing has clinical application, but few reports are available of its use within an active embryo transfer program. We evaluated results on biopsy of 459 embryos over one breeding season. There were no significant differences in pregnancy rate between biopsied and non-biopsied embryos (72% vs 73%) or for biopsied embryos recovered at the centre (73%) compared with those shipped overnight (72%). However, the pregnancy rate decreased significantly in shipped embryos biopsied ≥20h after collection. Overall, 86% of biopsies provided a sex diagnosis. The likelihood of a positive genomic (g) DNA result was significantly higher for biopsies from large blastocysts (96%) than from smaller embryos (70-85%). In total, 38% of biopsies were positive for Y chromosome DNA (Y-DNA) and were diagnosed as male. Subsequently, 95% of Y-DNA-positive embryos were confirmed as male and 78% of Y-DNA-negative embryos were confirmed as female. The accuracy of prediction of female (Y-DNA negative) was significantly higher when the biopsy sample was probed for Y-DNA only compared with probing for both gDNA and Y-DNA. We estimate that by transferring only Y-DNA-negative embryos, 3% of potential female pregnancies may have been lost, and production of male pregnancies was reduced by 72%.


Assuntos
Blastocisto/patologia , Embrião de Mamíferos/patologia , Cavalos/embriologia , Reação em Cadeia da Polimerase , Diagnóstico Pré-Implantação , Análise para Determinação do Sexo , Animais , Argentina , Biópsia , Cruzamento/economia , Cruzamento/métodos , Comércio , Transferência Embrionária/economia , Transferência Embrionária/métodos , Transferência Embrionária/veterinária , Feminino , Masculino , Reação em Cadeia da Polimerase/métodos , Reação em Cadeia da Polimerase/veterinária , Gravidez , Diagnóstico Pré-Implantação/métodos , Diagnóstico Pré-Implantação/veterinária , Análise para Determinação do Sexo/métodos , Análise para Determinação do Sexo/veterinária , Medicina Veterinária Esportiva/economia , Medicina Veterinária Esportiva/métodos , Medicina Veterinária Esportiva/organização & administração
3.
Aust Vet J ; 97(4): 108-115, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30919440

RESUMO

BACKGROUND: Veterinarians are required to interpret the significance of radiographic findings for sale, soundness and future racing performance of weanling and yearling Thoroughbreds. We investigated the prevalence and radiographic appearance of slab fractures of the third (T3) and central tarsal (Tc) bones. METHODS: Weanling and yearling horses with complete or incomplete T3 or Tc fracture were identified by searching a database of radiographs. The prevalence and radiographic appearance at initial diagnosis and after continued pasture turnout, as well as prognosis for racing, of fractures of T3 and Tc were determined. RESULTS: Fractures were identified in 186 tarsi (184 T3 fracture only, 1 Tc fracture only, 1 Tc and T3 fracture) of 157 horses (126 unilateral T3, 29 bilateral T3, 1 contralateral Tc and T3, 1 unilateral Tc and T3) from 7676 examinations. The prevalence of T3 and Tc fractures was 2.40 (95% CI 2.07, 2.76) and 0.04 (95% CI 0.01, 0.11) per 100 radiographic examinations respectively. Fractures were identified on the D556-65°MPlLO view and occurred by survey examination at 11.1 ± 1.3 months in 85.7% horses. At initial diagnosis, 84.3% of T3 fractures appeared incomplete and involved the distal articular surface. Fracture score improved (P < 0.001), and dorsal modelling (P < 0.001) and osteoarthritis score increased in the distal intertarsal joint (P < 0.001), but not the tarsometatarsal joint, between survey and repository examinations. Fractures healed by repository examination in 71.9% of tarsi if there was > 6 months between examinations. There was no difference in sale price, and horses with T3 fractures had fewer trials when 2 and 3 years old (P = 0.023), yet no difference in other parameters of racing success when 2 or 3 years old compared with controls. CONCLUSION: Tarsal slab fractures can occur in juvenile Thoroughbreds and most heal with continued pasture turnout of > 6 months. Further investigation is required to determine risk factors and before making firm conclusions regarding the optimal management, prognosis for racing and long-term soundness.


Assuntos
Fraturas Ósseas/veterinária , Doenças dos Cavalos/epidemiologia , Ossos do Tarso/lesões , Medicina Veterinária Esportiva/métodos , Animais , Austrália , Estudos de Casos e Controles , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/epidemiologia , Doenças dos Cavalos/diagnóstico por imagem , Cavalos , Prevalência , Estudos Retrospectivos , Ossos do Tarso/diagnóstico por imagem
4.
Schweiz Arch Tierheilkd ; 158(10): 677-689, 2016 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-27707681

RESUMO

INTRODUCTION: Heart murmurs and arrhythmias are common in horses. Assessment of their clinical relevance concerning health, performance, safety and longevity of sports horses is of highest importance. A comprehensive cardiovascular examination is crucial for diagnosis and assessment of the severity of disease. Recently, an expert panel of the American College of Veterinary Internal Medicine (ACVIM) and the European College of Equine Internal Medicine (ECEIM) developed a consensus statement containing recommendations for sports horses with heart disease. This article summarizes the most relevant recommendations for practitioners, considering the most common and most important cardiac disorders in adult sports horses. These include mitral, aortic and tricuspid insufficiency, ventricular septal defects, atrial fibrillation as well as supraventricular and ventricular arrhythmias. Despite the fact that most horses with cardiovascular disease maintain a sufficient performance capacity, regular evaluations are indicated in horses with clinically relevant disorders. Under certain circumstances, horses with moderate to severe structural disease, with persistent untreated atrial fibrillation and with certain ventricular arrhythmias might still be used by informed adult riders. Horses with complex ventricular arrhythmias, pulmonary hypertension or congestive heart failure must not be ridden or driven and should be retired.


INTRODUCTION: Chez le cheval, on rencontre fréquemment des souffles cardiaques et des arythmies. L'appréciation de l'importance clinique de ces découvertes par rapport à la santé, au potentiel de performance, à la sécurité et à l'espérance de vie chez les chevaux de sport est une priorité. Un examen cardiovasculaire complet est essentiel pour atteindre ce but et pour estimer la gravité de l'affection. L'American College of Veterinary Internal Medicine (ACVIM) et l'European College of Equine Internal Medicine (ECEIM) ont récemment engagé un groupe d'experts qui, dans une prise de position commune, a formulé des recommandations concernant les chevaux de sport atteints d'affections cardiaques. Le présent article résume les recommandations importantes pour les praticiens. On y prend en considération les affections cardiaques les plus fréquentes et les plus importantes chez les chevaux de sport adultes. Il s'agit des insuffisances mitrales, aortiques et tricuspides, des communications interventriculaires, des fibrillations atriales ainsi que des arythmies supraventriculaires et ventriculaires. Bien que la majorité des chevaux souffrant de pathologies cardio- vasculaires présentent des performances suffisantes, des contrôles réguliers sont indiqués chez les patients présentant des modifications cliniquement significatives. Les chevaux souffrant d'altérations structurelles d'importance moyenne à élevées, de fibrillations atriales persistantes non traitées ou de certaines arythmies ventriculaires peuvent, suivant les cas et après explication des risques encourus, continuer à être utilisés par des cavaliers adultes. Les chevaux présentant des arythmies ventriculaires complexes, de l'hypertension pulmonaire ou une insuffisance cardiaque congestive ne devraient pas être montés ou attelés.


Assuntos
Cardiopatias/veterinária , Doenças dos Cavalos/terapia , Esportes , Medicina Veterinária Esportiva/métodos , Animais , Cardiopatias/terapia , Cavalos , Medicina Veterinária Esportiva/normas
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