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1.
BMJ Case Rep ; 17(7)2024 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-39079903

RESUMO

Dermatofibrosarcoma protuberans (DFSP) is an aggressive tumour with multiple local recurrences and rare metastatic potential. Fibrosarcomatous transformation occurs in a few cases of DFSP which makes them more aggressive in terms of recurrence and metastasis. Here we report the case of a woman in her late 30s who presented with massive lower gastrointestinal (GI) bleeding with a history of multiple surgeries for DFSP on her anterior abdominal wall. The bleeding source was identified to be a mass lesion in the jejunum, which was excised. The patient recovered well and the histopathology revealed fibrosarcoma of the jejunum. Follow-up investigations showed multiple lung nodules, ascites and abdominal lymph nodes suggesting progressive disease. She is currently receiving chemotherapy and progressing well 3 months postoperatively. Patients with fibrosarcomatous changes within DFSP must be followed up closely as it is associated with increased metastatic potential.


Assuntos
Dermatofibrossarcoma , Hemorragia Gastrointestinal , Neoplasias do Jejuno , Neoplasias Cutâneas , Humanos , Dermatofibrossarcoma/complicações , Dermatofibrossarcoma/patologia , Dermatofibrossarcoma/diagnóstico , Dermatofibrossarcoma/secundário , Feminino , Hemorragia Gastrointestinal/etiologia , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/complicações , Neoplasias Cutâneas/secundário , Adulto , Neoplasias do Jejuno/secundário , Neoplasias do Jejuno/complicações , Neoplasias do Jejuno/cirurgia
2.
J Assoc Physicians India ; 72(5): 106-108, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38881122

RESUMO

A case describes a 49-year-old male patient who underwent emergency exploratory laparotomy for small intestinal perforation. Peritonitis was present due to perforation of the jejunal tumor. Resection of the jejunal tumor with perforation was performed followed by end-to-end anastomosis of the jejunum. The resected jejunal tumor was identified in the histopathological examination as metastatic from a clear cell variant of squamous cell/large cell carcinoma of the lung. It was associated with metastatic lesions in the brain. Metastasis from the lung carcinoma in the jejunum is a very rare condition predisposing to small intestinal perforation which is also associated with brain metastasis.


Assuntos
Neoplasias Encefálicas , Perfuração Intestinal , Neoplasias do Jejuno , Neoplasias Pulmonares , Humanos , Masculino , Pessoa de Meia-Idade , Perfuração Intestinal/etiologia , Perfuração Intestinal/cirurgia , Perfuração Intestinal/diagnóstico , Neoplasias do Jejuno/secundário , Neoplasias do Jejuno/cirurgia , Neoplasias do Jejuno/diagnóstico , Neoplasias Pulmonares/secundário , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/diagnóstico , Neoplasias Encefálicas/secundário , Carcinoma de Células Escamosas/secundário , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/cirurgia , Carcinoma de Células Grandes/secundário , Carcinoma de Células Grandes/cirurgia , Carcinoma de Células Grandes/diagnóstico
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