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1.
Clin Imaging ; 34(3): 222-5, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20416487

RESUMO

We report a case of a maturing immature intraventricular teratoma in a neonate. The computed tomography and magnetic resonance imaging and pathologic findings are described. The relevant literature is reviewed and management is discussed.


Assuntos
Neoplasias do Ventrículo Cerebral/congênito , Neoplasias do Ventrículo Cerebral/diagnóstico , Imageamento por Ressonância Magnética , Teratoma/congênito , Teratoma/diagnóstico , Tomografia Computadorizada por Raios X , Feminino , Humanos , Recém-Nascido
2.
Childs Nerv Syst ; 24(12): 1499-503, 2008 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18629509

RESUMO

OBJECTS: Congenital Subependymal giant cell astrocytoma (SEGA), diagnosed in fetal and neonatal period, is extremely rare. Previous studies have reported poor surgical outcomes of this small group of patients. We encountered a patient diagnosed as congenital SEGA and report the surgical outcome along with interesting immuno-phenotypes of giant tumor cells. CASE: Ventriculomegaly and a hypoechoic mass near the foramen of Monro were detected in a fetus on prenatal ultrasonography in the 35th week of gestation. Surgery was scheduled 2 months later to reduce the risk of operative complications. At postnatal 2 months, gross total resection of the tumor was achieved without complications. The patient had been followed up for 1 year without tumor recurrence. In double immunofluorescence, the prototype cells of SEGA expressed a variety of neural stem cell (nestin and Sox2) and radial glial cell markers (vimentin and brain lipid-binding protein), in addition to glutamate/aspartate transporter and glial fibrillary acidic protein. CONCLUSIONS: Congenital SEGA can be successfully treated with judicious use of observation period and careful evaluation of general conditions. Pathological findings support the concept that SEGA may originate from aberrant radial glial cells in the developing brain.


Assuntos
Astrocitoma/cirurgia , Neoplasias do Ventrículo Cerebral/cirurgia , Doenças Fetais/cirurgia , Astrocitoma/congênito , Astrocitoma/diagnóstico , Proteínas de Transporte/biossíntese , Neoplasias do Ventrículo Cerebral/congênito , Neoplasias do Ventrículo Cerebral/diagnóstico , Proteína 7 de Ligação a Ácidos Graxos , Feminino , Doenças Fetais/diagnóstico , Doenças Fetais/metabolismo , Imunofluorescência/métodos , Humanos , Recém-Nascido , Proteínas de Filamentos Intermediários/biossíntese , Masculino , Proteínas do Tecido Nervoso/biossíntese , Nestina , Gravidez , Diagnóstico Pré-Natal , Fatores de Transcrição SOXB1/biossíntese , Proteínas Supressoras de Tumor/biossíntese , Ultrassonografia Pré-Natal , Vimentina/biossíntese
3.
Pediatr Neurosurg ; 43(4): 338-42, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17627155

RESUMO

Germ cell tumors comprise 0.4-3.1% of all intracranial tumors, and teratoma constitutes 9-30% of them. Congenital intracranial tumors are very rare and only account for 0.5-1.5% of all childhood brain tumors. The most common type of these tumors present at birth is teratomas, which represent 0.5% of all intracranial tumors. Most teratomas are midline tumors located predominantly in the sellar and pineal regions. In this study, we report a neonatal intracranial immature teratoma at the lateral ventricle because of its rare location. A 5-day-old female neonate presented with a history of irritability and left eye protrusion since birth. A head computed tomographic (CT) scan and magnetic resonance imaging (MRI) disclosed a large tumor filling the left lateral ventricle and extending into the ipsilateral retro-orbital space. With left frontotemporoparietal craniotomy, a large grayish-white lobulated vascular mass was encountered, and total removal of tumor was performed. Histological examination revealed the diagnosis of immature teratoma. The prognosis of congenital intracranial immature teratoma is usually poor because the lesions are extensive when they are identified. Prenatal ultrasonography is necessary for the prenatal diagnosis. Fetal MRI should be made for the evaluation of intracranial tumor. If the tumor is detected before the 24th week of gestation, termination of the pregnancy should be considered.


Assuntos
Neoplasias do Ventrículo Cerebral/congênito , Neoplasias do Ventrículo Cerebral/patologia , Ventrículos Laterais , Teratoma/congênito , Teratoma/patologia , Neoplasias do Ventrículo Cerebral/cirurgia , Feminino , Humanos , Recém-Nascido , Teratoma/cirurgia
4.
Neurol Res ; 27(1): 53-6, 2005 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-15829159

RESUMO

OBJECTIVE: Congenital intracranial tumors are very rare and only account for 0.5-1.5% of all childhood brain tumors. The most common type of these tumors present at birth is teratomas, which represent 0.5% of all intracranial tumors. Most teratomas are midline tumors located predominantly in the sellar and pineal regions. In this study, we report a neonatal intracranial immature teratoma at the lateral ventricle because of its rare location. CASE REPORT: A 3-day-old female neonate presented with a history of irritability, vomiting, and recurrent generalized clonic seizures since birth. A head computed tomographic scan and magnetic resonance imaging disclosed a large tumor filling the right lateral ventricle and extending into the ipsilateral posterior fossa. With right parieto-occipital craniotomy, large grayish-white lobulated vascular mass was encountered and total removal of tumor was performed. Histological examination revealed the diagnosis of immature teratoma. CONCLUSION: The prognosis of congenital intracranial immature teratoma is usually poor because the lesions are extensive when they are identified. Prenatal ultrasonography is necessary for the prenatal diagnosis. Fetal magnetic resonance imaging should be made for the evaluation of intracranial tumor. If the tumor is detected before the 24 week of gestation, termination of the pregnancy should be considered.


Assuntos
Neoplasias do Ventrículo Cerebral/congênito , Ventrículos Laterais/patologia , Teratoma/congênito , Neoplasias do Ventrículo Cerebral/patologia , Pré-Escolar , Feminino , Humanos , Imageamento por Ressonância Magnética/métodos , Literatura de Revisão como Assunto , Teratoma/patologia , Tomografia Computadorizada por Raios X/métodos
8.
Neurol Med Chir (Tokyo) ; 41(2): 94-6, 2001 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-11255635

RESUMO

A 20-day-old female neonate presented with an immature teratoma in the midline posterior fossa. The tumor was totally removed but the patient died of pneumonia. Teratoma is a rare tumor, but very difficult to treat as the patients tend to be young, and the outcome is very poor.


Assuntos
Neoplasias do Ventrículo Cerebral/congênito , Quarto Ventrículo , Teratoma/congênito , Neoplasias do Ventrículo Cerebral/patologia , Neoplasias do Ventrículo Cerebral/cirurgia , Fossa Craniana Posterior , Evolução Fatal , Quarto Ventrículo/patologia , Quarto Ventrículo/cirurgia , Humanos , Recém-Nascido , Teratoma/patologia , Teratoma/cirurgia , Tomografia Computadorizada por Raios X
9.
Childs Nerv Syst ; 13(5): 244-9, 1997 May.
Artigo em Inglês | MEDLINE | ID: mdl-9224912

RESUMO

The III ventricle is an uncommon location for choroid plexus papilloma at any age. We describe three new cases of choroid plexus papillomas of the III ventricle (CPPs). All children were boys under 4 months of age and all presented with increased intracranial pressure, hydrocephalus and macrocephaly. The three were examined by preoperative computed tomography (CT) and ultrasonography. Two of them were investigated with magnetic resonance imaging (MRI). The first case was treated with a right corticofrontal transventricular approach and subtotal resection, so that he required a second operation through a transcallosal approach. In the other two cases a transcallosal approach was used. Two children needed permanent ventriculo-peritoneal shunts. The average follow-up of 4.3 years has revealed no neurological deficits in any case. The timing of and the need for shunting are major considerations. Clinical and imaging follow-up (CT and/or ultrasonography) are very helpful in controlling postoperative hydrocephalus and subdural effusion, avoiding unnecessary shunting in many cases. The operative approaches, transcortical and transcallosal, are discussed.


Assuntos
Neoplasias do Ventrículo Cerebral/congênito , Glioma/congênito , Neoplasias do Ventrículo Cerebral/diagnóstico , Neoplasias do Ventrículo Cerebral/patologia , Neoplasias do Ventrículo Cerebral/cirurgia , Craniotomia/métodos , Diagnóstico por Imagem , Seguimentos , Glioma/diagnóstico , Glioma/patologia , Glioma/cirurgia , Humanos , Lactente , Masculino , Complicações Pós-Operatórias/diagnóstico , Reoperação , Derivação Ventriculoperitoneal
10.
Neurol Med Chir (Tokyo) ; 37(4): 346-9, 1997 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-9136561

RESUMO

A neonate male who developed cavernous angioma was born with a severe intraventricular hemorrhage and intraparenchymal hemorrhage in the basal ganglia. magnetic resonance imaging revealed a large, non-enhanced hematoma that packed the lateral ventricle. Surgery on the 2nd day of life verified a cavernous angioma associated with minimal hemosiderin and gliosis. Fetal cavernous angiomas, unlike such malformations in other age groups, can present with a devastating hemorrhage because of the lack of gliosis in the surrounding brain.


Assuntos
Hemorragia Cerebral/congênito , Neoplasias do Ventrículo Cerebral/congênito , Hemangioma Cavernoso/congênito , Hemorragia Cerebral/diagnóstico , Hemorragia Cerebral/cirurgia , Neoplasias do Ventrículo Cerebral/diagnóstico , Neoplasias do Ventrículo Cerebral/cirurgia , Ventrículos Cerebrais/patologia , Feminino , Hemangioma Cavernoso/diagnóstico , Hemangioma Cavernoso/cirurgia , Humanos , Hidrocefalia/diagnóstico , Hidrocefalia/cirurgia , Recém-Nascido , Imageamento por Ressonância Magnética , Masculino , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/cirurgia , Gravidez , Reoperação , Ultrassonografia Pré-Natal , Derivação Ventriculoperitoneal
11.
Pediatr Neurosurg ; 24(1): 5-7, 1996.
Artigo em Inglês | MEDLINE | ID: mdl-8817610

RESUMO

An intradural, intramedullary lipoma originating within the upper cervical cord with significant extension into the posterior fossa is reported in an infant. Two additional lipomas were found in the lumbar region. This constellation of findings represents the first description of multiple intradural, intramedullary spinal lipomas with extensive intracranial involvement.


Assuntos
Neoplasias do Ventrículo Cerebral/congênito , Lipoma/congênito , Neoplasias Primárias Múltiplas/congênito , Neoplasias da Medula Espinal/congênito , Neoplasias do Ventrículo Cerebral/diagnóstico , Neoplasias do Ventrículo Cerebral/cirurgia , Fossa Craniana Posterior/patologia , Fossa Craniana Posterior/cirurgia , Craniotomia , Humanos , Lactente , Lipoma/diagnóstico , Lipoma/cirurgia , Imageamento por Ressonância Magnética , Masculino , Neoplasias Primárias Múltiplas/diagnóstico , Neoplasias Primárias Múltiplas/cirurgia , Exame Neurológico , Medula Espinal/patologia , Medula Espinal/cirurgia , Neoplasias da Medula Espinal/diagnóstico , Neoplasias da Medula Espinal/cirurgia
14.
Pediatr Neurol ; 8(4): 307-9, 1992.
Artigo em Inglês | MEDLINE | ID: mdl-1388423

RESUMO

Intracranial lipomas are rare and usually do not have clinical expression. They are located most commonly in the interhemispheric fissure and may also be found in the quadrigeminal, ambient, chiasmatic, interpeduncular, sylvian, and perimesencephalic cisterns. Interhemispheric lipomas may be associated with choroid plexus lipomas. The ultrasonography, computed tomography, and magnetic resonance imaging findings are reported in a neonate with lateral ventricular choroid plexus lipomas and interhemispheric lipoma associated with agenesis of the corpus callosum.


Assuntos
Agenesia do Corpo Caloso , Neoplasias do Ventrículo Cerebral/congênito , Diagnóstico por Imagem , Lipoma/congênito , Calcinose/congênito , Calcinose/diagnóstico , Neoplasias do Ventrículo Cerebral/diagnóstico , Neoplasias do Plexo Corióideo/congênito , Neoplasias do Plexo Corióideo/diagnóstico , Corpo Caloso/patologia , Ecoencefalografia , Feminino , Seguimentos , Humanos , Lactente , Recém-Nascido , Lipoma/diagnóstico , Imageamento por Ressonância Magnética , Tomografia Computadorizada por Raios X
15.
J Child Neurol ; 4(2): 127-30, 1989 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-2715609

RESUMO

A newborn infant with marked hydrocephalus had a large papilloma of the choroid plexus originating in the fourth ventricle and infiltrating the brain stem. The computed tomographic (CT) scan appearance was distinctive, showing vascularity and marked enhancement with contrast medium. Histological confirmation was made from several surgical sites. Total removal of the tumor was not possible. Review of congenital choroid plexus brain tumors reveals the location of this child's tumor in the fourth ventricle to be uncommon.


Assuntos
Neoplasias do Ventrículo Cerebral/congênito , Plexo Corióideo/anormalidades , Papiloma/congênito , Neoplasias do Ventrículo Cerebral/patologia , Plexo Corióideo/patologia , Feminino , Humanos , Recém-Nascido , Microscopia Eletrônica , Papiloma/patologia , Tomografia Computadorizada por Raios X
16.
Zentralbl Neurochir ; 50(3-4): 171-5, 1989.
Artigo em Inglês | MEDLINE | ID: mdl-2642234

RESUMO

Four infants with choroid plexus papillomas which were successfully treated with surgery are described. All patients showed the clinical signs of increased intracranial pressure and hydrocephalus within 8 weeks after birth. The tumors were in the lateral ventricles and histologically three of them were benign papillomas and other one was a malignant papilloma. Computerized tomography scan was useful for the diagnosis of both of the tumor and the hydrocephalus that was caused by the overproduction of cerebrospinal fluid and/or the obstruction of it's pathway. The tumor stain on the angiograms was noticed in two patients. Three patients have grown normally in both physical and mental functions after the surgical treatment, whereas one showed psychomotor retardation because of poorly controlled hydrocephalus.


Assuntos
Neoplasias do Ventrículo Cerebral/congênito , Plexo Corióideo/anormalidades , Papiloma/congênito , Angiografia Digital , Neoplasias do Ventrículo Cerebral/diagnóstico por imagem , Neoplasias do Ventrículo Cerebral/cirurgia , Derivações do Líquido Cefalorraquidiano , Plexo Corióideo/diagnóstico por imagem , Plexo Corióideo/cirurgia , Feminino , Humanos , Recém-Nascido , Masculino , Papiloma/diagnóstico por imagem , Papiloma/cirurgia , Tomografia Computadorizada por Raios X
18.
Digitale Bilddiagn ; 7(4): 187-8, 1987 Dec.
Artigo em Alemão | MEDLINE | ID: mdl-3436122

RESUMO

The authors report on a patient of 5 months of age in whom the computer tomogram revealed a space-occupying growth without any sign of a compressive intracranial process. Histological diagnosis yielded the rare occurrence of a fibrillary astrocytoma of grade 2.


Assuntos
Astrocitoma/congênito , Neoplasias do Ventrículo Cerebral/congênito , Tomografia Computadorizada por Raios X , Astrocitoma/diagnóstico por imagem , Neoplasias do Ventrículo Cerebral/diagnóstico por imagem , Humanos , Lactente , Masculino
19.
Klin Padiatr ; 197(1): 44-9, 1985.
Artigo em Alemão | MEDLINE | ID: mdl-2983144

RESUMO

Using the open fontanelle as an acoustic window brain tumours were diagnosed by gray scale ultrasonography in 3 infants aged 1 day to 5 months. The tumours were characterized by their echo dense structure and their good delimination from the surrounding brain. In 2 children the tumour was localized infratentorially (medulloblastoma and unclassified neuroectodermal tumour) and had caused an occlusive hydrocephalus. Both children died aged 3 and 5 months in central nervous dysregulation. One child suffered from plexus papilloma which had caused a hypersecretory hydrocephalus. After resection of the tumour the hydrocephalus decreased without any further treatment. Comparison with axial computed tomography and autopsy findings showed, that gray scale ultrasonography is equally efficient in diagnosing brain tumours and associated hydrocephalus.


Assuntos
Neoplasias Encefálicas/congênito , Ecoencefalografia/métodos , Neoplasias Cerebelares/congênito , Neoplasias do Ventrículo Cerebral/congênito , Plexo Corióideo/patologia , Feminino , Humanos , Hidrocefalia/diagnóstico , Lactente , Recém-Nascido , Masculino , Meduloblastoma/congênito , Neoplasias Embrionárias de Células Germinativas/congênito , Papiloma/congênito , Tomografia Computadorizada por Raios X
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