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6.
Fam Syst Health ; 42(1): 130-132, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38647495

RESUMO

Reviews the book, Handbook of Positive Youth Development: Advancing Research, Policy, and Practice in Global Contexts edited by Radosveta Dimitrova and Nora Wiium (2021). This volume deals with both the applications and interventions of positive youth development (PYD) in the context of families and other systems in global contexts. Additionally, it advances empirical and theoretical knowledge in PYD, refinement of methodological issues, and measurement and integration of PYD-related knowledge with policy, research, and practice. This book will interest a broad spectrum of readers, including social scientists, students, professionals, policymakers, and practitioners from various disciplines. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Assuntos
Desenvolvimento do Adolescente , Humanos , Adolescente , Pesquisa/tendências
9.
Bioinspir Biomim ; 19(4)2024 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-38631363

RESUMO

This paper presents a bibliometrics analysis aimed at discerning global trends in research on 'biomimetics', 'biomimicry', 'bionics', and 'bio-inspired' concepts within civil engineering, using the Scopus database. This database facilitates the assessment of interrelationships and impacts of these concepts within the civil engineering domain. The findings demonstrate a consistent growth in publications related to these areas, indicative of increasing interest and impact within the civil engineering community. Influential authors and institutions have emerged, making significant contributions to the field. The United States, Germany, and the United Kingdom are recognised as leaders in research on these concepts in civil engineering. Notably, emerging countries such as China and India have also made considerable contributions. The integration of design principles inspired by nature into civil engineering holds the potential to drive sustainable and innovative solutions for various engineering challenges. The conducted bibliometrics analysis grants perspective on the current state of scientific research on biomimetics, biomimicry, bionics, and bio-inspired concepts in the civil engineering domain, offering data to predict the evolution of each concept in the coming years. Based on the findings of this research, 'biomimetics' replicates biological substances, 'biomimicry' directly imitates designs, and 'bionics' mimics biological functions, while 'bio-inspired' concepts offer innovative ideas beyond direct imitation. Each term incorporates distinct strategies, applications, and historical contexts, shaping innovation across the field of civil engineering.


Assuntos
Bibliometria , Biomimética , Biônica , Biônica/tendências , Engenharia , Bases de Dados Factuais , Pesquisa/tendências
10.
RNA ; 30(5): 530-536, 2024 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-38531650

RESUMO

Pseudouridine is an abundant mRNA modification found in diverse organisms ranging from bacteria and viruses to multicellular plants and humans. New developments in pseudouridine profiling provide quantitative tools to map mRNA pseudouridylation sites. Sparse biochemical studies establish the potential for mRNA pseudouridylation to affect most stages of the mRNA life cycle from birth to death. This recent progress sets the stage for deeper investigations into the molecular and cellular functions of specific mRNA pseudouridines, including in disease.


Assuntos
RNA Mensageiro , Pesquisa , RNA Mensageiro/química , RNA Mensageiro/metabolismo , Transferases Intramoleculares/metabolismo , Transcrição Gênica , Precursores de RNA/química , Precursores de RNA/metabolismo , Proteínas de Ligação a RNA/metabolismo , Biossíntese de Proteínas , Ligação Proteica , Humanos , Animais , Pesquisa/tendências
15.
Biochem Med (Zagreb) ; 34(1): 010502, 2024 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-38125621

RESUMO

YKL-40 or Chitinase-3-Like Protein 1 (CHI3L1) is a highly conserved glycoprotein that binds heparin and chitin in a non-enzymatic manner. It is a member of the chitinase protein family 18, subfamily A, and unlike true chitinases, YKL-40 is a chitinase-like protein without enzymatic activity for chitin. Although its accurate function is yet unknown, the pattern of its expression in the normal and disease states suggests its possible engagement in apoptosis, inflammation and remodeling or degradation of the extracellular matrix. During an inflammatory response, YKL-40 is involved in a complicated interaction between host and bacteria, both promoting and attenuating immune response and potentially being served as an autoantigen in a vicious circle of autoimmunity. Based on its pathophysiology and mechanism of action, the aim of this review was to summarize research on the growing role of YKL-40 as a persuasive biomarker for inflammatory diseases' early diagnosis, prediction and follow-up (e.g., cardiovascular, gastrointestinal, endocrinological, immunological, musculoskeletal, neurological, respiratory, urinary, infectious) with detailed structural and functional background of YKL-40.


Assuntos
Biomarcadores , Proteína 1 Semelhante à Quitinase-3 , Doença , Inflamação , Proteína 1 Semelhante à Quitinase-3/metabolismo , Inflamação/enzimologia , Inflamação/genética , Biomarcadores/sangue , Biomarcadores/metabolismo , Doença/genética , Pesquisa/tendências , Humanos , Animais , Diagnóstico Precoce
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