Evaluation of marginal and internal adaptation of veneers generated by the guided prosthetic tooth preparation system.

OBJECTIVE: This in vitro study aimed to assess and contrast the marginal and internal adaptation of all-ceramic prefabricated veneers manufactured via the FirstFit guided tooth preparation system against all-ceramic veneers produced using the chairside Computer-Aided Design/Computer Aided Manufacture (CAD/CAM) system following identical guided preparation protocols. MATERIALS AND METHODS: Two main groups were included, with 16 lithium disilicate veneers per group. Four typodonts were used for the test (FirstFit) and control CAD/CAM groups. Intraoral scans created master casts and preparation guides. Guides performed preparations on typodont teeth (two central incisors and two lateral incisors). Prepared teeth were scanned (CEREC Omnicam) to design and mill CAD/CAM veneers. Marginal gap thickness and cement space thickness were measured using light microscopy at four locations: marginal, cervical internal, middle internal, and incisal internal. RESULTS: No significant difference existed between groups for marginal adaptation (p = 0.058) or incisal internal adaptation (p = 0.076). The control group had significantly lower values for middle internal adaptation (p = 0.023) and cervical internal adaptation (p = 0.019). CONCLUSIONS: Guided preparation evaluation showed no significant differences in marginal or incisal internal adaptation. The CAD/CAM group had significantly lower middle and cervical internal adaptation values.

Computer-aided design software-enabled preclinical prosthodontic training: A digital education technique.

The prosthodontics preclinical training modules involve textbook-based two-dimensional (2D) ideal images and practicing on manikin models to emulate ideal tooth preparations and teeth arrangements. Relying solely on 2D images as objectives for preclinical exercises limits the trainee's creative skills to instructions of textbooks and clinical instructions received. With advancements in digital dentistry, dental trainees should have early exposure to the three-dimensional (3D) rendering of ideal preclinical objectives. A dental education technique using computer-aided design software and smartphones is described that will allow 3D rendering of ideal prosthodontic training assignments allowing early exposure to digital dentistry for dental training students.

Effect of cement gap and drill offset on the marginal and internal fit discrepancies of crowns designed with different tooth preparations.

AIM: The aim of the present study was to evaluate the effect of cement gap and drill offset on the marginal and internal fit discrepancies of crowns designed with different tooth preparations. MATERIALS AND METHODS: Five tooth preparations were constructed, and crowns with different cement gaps and drill offsets were obtained. Then, best-fit alignment was performed on the crowns with the corresponding tooth preparations, and the fit discrepancies were expressed by color-coded difference images and root mean square (RMS) values. The RMS values of each group were analyzed by the rank-based Scheirer-Ray-Hare test (α = 0.05). RESULTS: The color segments in the sharp line angles area of the Sharp line angles group changed significantly before and after the drill offset. The cement gap had a significant effect on the marginal, internal, or overall fit discrepancies of the five design groups (P < 0.001), while the drill offset had a significant effect on the marginal fit discrepancies of the Shoulder-lip group and the internal or overall fit discrepancies of the Sharp line angles group (P < 0.001). Additionally, the interaction effect between cement gap and drill offset was significant for the marginal fit discrepancies of the Shoulder-lip group and the internal or overall fit discrepancies of the Sharp line angles group (P < 0.01). CONCLUSIONS: The cement gap and drill offset had a significant adverse effect on the marginal or internal fit discrepancies of the crowns designed with the shoulder-lip and sharp line angles designs. Tooth preparation designs with intense curvature changes such as shoulder-lip and sharp line angles should be avoided clinically.

Impact of marginal defects on the accuracy of automated finish line detection in tooth preparation.

AIM: The present study aimed to evaluate the accuracy of automated detection of preparation finish lines in teeth with defective margins. MATERIALS AND METHODS: An extracted first molar was prepared for a full veneer crown, and marginal defects were created and scanned (discontinuity of finish line: 0.5, 1.0, and 1.5 mm; additional line angle: connected, partially connected, and disconnected). Six virtual defect models were entered into CAD software and the preparation finish line was designated by 20 clinicians (CAD-experienced group: n = 10; CAD-inexperienced group: n = 10) using the automated finish line detection method. The accuracy of automatic detection was evaluated by calculating the 3D deviation of the registered finish line. The Kruskal-Wallis and Mann-Whitney U tests were used for between-group comparisons (α = 0.05). RESULTS: The deviation values of the registered finish lines were significantly different according to conditions with different amounts of finish line discontinuity (P < 0.001). There was no statistical difference in the deviation of the registered finish line between models with additional line angles around the margin. Moreover, no statistical difference was found in the results between CAD-experienced and CAD-inexperienced operators. CONCLUSIONS: The accuracy of automated finish line detection for tooth preparation can differ when the finish line is discontinuous. The presence of an additional line angle around the preparation margin and prior experience in dental CAD software do not affect the accuracy of automated finish line detection.

[Prediction, analysis and application of learning curve of tooth preparation for all ceramic crowns of maxillary central incisors].

OBJECTIVE: To predict the learning curve of tooth preparation for all ceramic crowns of maxillary central incisors on phantom head simulators for graduate students participating in standardized dental resident training based on the modified Wright learning curve model, then to analyze and applicate the learning curve. METHODS: Twelve graduate students participating in standardized dental resident training were selected to prepare the resin maxillary central incisors on phantom head simulators for all ceramic crowns 4 times. The results of preparation were evaluated by 3 prosthetic experts with at least 10 years' experience focusing on the reduction, contour, taper, shoulder, finish line, margin placement, adjacent tooth injury, and preparation time for tooth preparation. The learning rate of tooth preparation was calculated by scores of tooth preparation of 4 times. The learning curve of tooth preparation was predicted based on the modified Wright learning curve model. According to the criteria of standardized training skill examinations for dental residents in Beijing, 80 was taken as the qualified standard score. The minimum training times for tooth preparation to satisfy the qualified standard score (80) was calculated, to analyze the characteristics of learning curve and evaluate the effectiveness of tooth preparation. RESULTS: The scores of 4 tooth preparation were 64.03±7.80, 71.40±6.13, 74.33±5.96, and 75.98±4.52, respectively. The learning rate was (106±4)%, which showed the learning curve an upward trend. There were no significant differences between the qualified standard score and the predicted scores of tooth preparation from the 5th preparation to the 13th preparation (P > 0.05). The predicted score of the 14th preparation was higher than the qualified standard score (P < 0.05). CONCLUSION: The trend of the learning curve of tooth preparation for all ceramic crowns of maxillary central incisors on phantom head simulators for graduate students participating in standardized dental resident training is upward, which predicts the minimum training times higher than the qualified standard score is 14 times.

Reliability of automatic finish line detection for tooth preparation in dental computer-aided software.

PURPOSE: This study aimed to investigate the accuracy of automatic tooth finish line registration compared to manual registration with regard to various finish line configurations and dental computer-aided design (CAD) software. METHODS: Finish line registrations were performed on 15 digital tooth models with different finish line configurations (edge roundness radius = 0 mm, 0.2 mm, and 0.4 mm; edge angle = 30°, 60°, 90°, 120°, and 150°) using automatic and manual methods for designing virtual copings (N = 150). The discrepancies between the registered finish line extracted from the copings and the actual finish line segmented from the digitized tooth model were measured. Three-way analysis of variance (ANOVA) and post-hoc analyses with Bonferroni correction (α = 0.05) were used to analyze the results. RESULTS: The finish line configurations, registration methods, and CAD software interacted with the accuracy of the registered finish line (p = 0.001). The automatic finish line registration method exhibited larger error values than the manual method, especially at high finish line edge roundness and obtuse edge angles for both EXOCAD and R2CAD software (p < 0.001). The difference in dental CAD software affected the registration accuracy in the automatic method (p < 0.001), but not in the manual method (p = 0.676). CONCLUSIONS: Finish line registration errors may occur when the automatic registration method is applied to the indistinct edge of tooth preparation. The accuracy of the automatic finish line registration could differ according to the CAD software program.

Marginal Integrity of CAD/CAM Ceramic Crowns Using Two Different Finish Line Designs.

OBJECTIVE: Research on evaluation of crowns made by the latest contemporary dental computer-aided design/computer-aided manufacturing (CAD/CAM) systems for their marginal adaptation is scarce. The purpose of this in vitro study was to evaluate the marginal integrity of crowns fabricated by the latest Chairside Economical Restorations of Esthetic Ceramic (CEREC) system using 2 different finish line preparation designs: chamfer and shoulder. MATERIALS AND METHODS: Typodont teeth were divided equally into 2 groups, A and B. The teeth were prepared for full coverage crowns with a shoulder (group A) and chamfer (group B) finish line design. An experienced prosthodontist prepared all crown preparations. Evaluation of 6 sites per sample was completed by 2 calibrated, experienced prosthodontists using the modified US Public Health Services (USPHS) criteria. The descriptive statistics and Z-test were used to evaluate the results. RESULTS: A total of 180 teeth were included in the study (90 teeth in each group). Only 2 crowns in group A and 1 crown in group B were clinically unacceptable. There was no statistical significance (p = 0.282) between the 2 groups regarding finish line design. CONCLUSIONS: The CEREC system provides clinically acceptable crowns and can safely be utilized in dental treatment. Therefore, CAD/CAM restorations could be considered as a safe treatment modality by dental professionals.

Fit of tooth-supported zirconia single crowns-A systematic review of the literature.

PURPOSE: The purpose of this study is to systematically map all the factors that influence the fit and adaptation of zirconia crowns and/or copings. MATERIALS AND METHODS: The investigational strategy involved carrying out an electronic search between December 1, 2009 and September 1, 2019 through the Embase and Medline databases using Boolean operators to locate appropriate articles. RESULTS: A total of 637 articles were discovered after the removal of duplicates, and 46 of these were selected for evaluation. Further, a quality assessment was performed using GRADE evaluation criteria. CONCLUSIONS: Shoulder finish line preparations had slightly better marginal fit compared to chamfer finish lines. Crowns obtained from digital impressions had comparable to superior marginal adaptation compared to conventional impressions. Increasing cement space showed to improve zirconia crown adaptation. Cementation and veneering zirconia frameworks found to increase the marginal and internal gaps. Limited information is available on the effect of the alteration of sintering time/Temperature and/or sintering techniques on the adaptation of zirconia crowns. Most of the selected studies had a moderate quality assessment evaluation. Future studies could investigate the chair-side, ultra-fast sintering effect on the marginal gap of zirconia crowns.

3D Printed Teeth for the Preclinical Education of Dental Students.

A need for more realistic tooth models for education has often been expressed by dental students. The aim of this study was to design and create 3D printed teeth with anatomical details for use in preclinical dental education. A tooth with realistic carious lesions and pulp cavity was designed, and this tooth was used in 2018 with 47 dental students for preclinical education in caries excavation, direct capping of the pulp, core build-up, and crown preparation. The students had the ability to identify the carious lesions by a simulated radiograph and by tactile sense of the consistency. The benefits of the 3D printed tooth were evaluated by a questionnaire. The printed tooth was evaluated by grades (1=excellent, 2=good, 3=satisfactory, 4=adequate, 5=poor). The students gave the tooth an overall mean grade of 1.9, with a grade of 2.0 for the haptic impression, 1.5 for the exercise, 1.9 for the examination, and 1.5 for high practical relevance in contrast to a standard model tooth. The new features of the printed tooth were given a mean grade of 2.0 for the radiograph, 2.3 for consistency of the caries, 2.0 for the tooth filling, and 1.7 for the pulp capping as realistic. The students had the possibility to generate a complete concept for prosthodontic tooth treatment on an artificial 3D printed tooth.

Lean Methods Applied to CAD/CAM Pedagogy in the Dental Simulation Laboratory.

Dental education is incorporating computer-assisted design/computer-assisted manufacturing (CAD/CAM) into patient care delivery. The aim of this study was to determine if lean production methods applied to the preclinical phase of dental education would reduce the students' time (efficiency) to complete CAD/CAM indirect restorations (CAD/CAM IR) without compromising the desired quality of the CAD/CAM tooth preparations (effectiveness). In 2016, all third-year students at one U.S. dental school were randomly assigned to control and research groups (approximately 33 per group). The control group was taught using existing methods, while the course was redesigned to incorporate lean methods for the research group. Cycle times of the CAD/CAM IR process for both groups were collected and statistically analyzed to compare the effectiveness of the redesign. Standardized grading forms and tools were used to assess the quality of the CAD/CAM tooth preparations. The research group demonstrated significantly faster preparation times with both crowns and onlays (p<0.05) than the control group. The research group also produced CAD/CAM crown and onlay designs at a significantly faster pace than the control group (p<0.05). There was no significant difference between the control and research groups associated with the scanning process times (p>0.05) nor in the quality of the CAD/CAM tooth preparations (p>0.05). This study demonstrated that lean methods applied to pedagogy significantly decreased preparation and design times in a CAD/CAM restorative dentistry course without compromising the quality of the CAD/CAM tooth preparations.

Marginal Fit of Metal-Ceramic Copings: Effect of Luting Cements and Tooth Preparation Design.

PURPOSE: To evaluate the effect of the triad finish line design, axial wall convergence angle, and luting cement on the marginal fit of metal copings used in metal-ceramic crowns. MATERIALS AND METHODS: Schematic dies and their respective copings were cast in NiCr alloy. The dies exhibited the following finish line/convergence angle combinations: sloping shoulder/6°, sloping shoulder/20°, shoulder/6°, shoulder/20°. Marginal fit was evaluated under a stereomicroscope, before and after cementation. Copings were air-abraded with 50 µm Al2 O3 particles and cemented with Cimento de Zinco, RelyX U100, or Panavia F cements (n = 10/group). Data were square-root transformed and analyzed by 3-way factorial random effect model and Tukey's post hoc test (α = 0.05). RESULTS: Statistical analysis showed significance for the interactions finish line and convergence angle (p < 0.05), convergence angle and time (p < 0.001), and luting cement and time (p < 0.001). Sloping shoulder/20° provided the highest marginal discrepancy when compared to the other finish line/convergence angle combinations, which were statistically similar among each other. For both convergence angles and for all luting cements, the marginal discrepancy was significantly higher after cementation. Before and after cementation, 6° provided better marginal fit than 20°. After cementation, Panavia F provided higher marginal discrepancy than Cimento de Zinco. CONCLUSION: Lower convergence angle combined with shoulder and a low-consistency luting cement is preferable to cement metal copings.

Preparation Ferrule Design Effect on Endocrown Failure Resistance.

PURPOSE: To evaluate the effect of preparation ferrule inclusion with fracture resistance of mandibular molar endocrowns. MATERIALS AND METHODS: Recently extracted mandibular third molars were randomly divided into 3 groups (n = 12) with the coronal tooth structure removed perpendicular to the root long axis approximately 2 mm above the cemento-enamel junction with a slow-speed diamond saw. The pulp chamber was exposed using a diamond bur in a high-speed handpiece with pulpal remnants removed and canals instrumented using endodontic hand instruments. The chamber floor was restored using a resin core material with a two-step, self-etch adhesive and photopolymerized with a visible light-curing unit to create a 2 mm endocrown preparation pulp chamber extension. One and two millimeter ferrule height groups were prepared using a diamond bur in a high-speed handpiece following CAD/CAM guidelines. Completed preparation surface area was determined using a digital measuring microscope. Scanned preparations were restored with lithium disilicate restorations with a self-adhesive resin luting agent. All manufacturer recommendations were followed. Specimens were stored at 37°C/98% humidity and tested to failure after 24 hours at a 45° angle to the tooth long axis using a universal testing machine. Failure load was converted to MPa using the available bonding surface area with mean data analyzed using Kruskal-Wallis/Dunn (p = 0.05). RESULTS: Calculated failure stress found no difference in failure resistance among the three groups; however, failure load results identified that the endocrown preparations without ferrule had significantly lower fracture load resistance. Failure mode analysis identified that all preparations demonstrated a high number of catastrophic failures. CONCLUSIONS: Under the conditions of this study, ferrule-containing endocrown preparations demonstrated significantly greater failure loads than standard endocrown restorations; however, calculated failure stress based on available surface area for adhesive bonding found no difference between the groups. Lower instances of catastrophic failure were observed with the endocrown preparations containing 1 mm of preparation ferrule design; however, regardless of the presence of ferrule, this study found that all endocrown restorations suffered a high proportion of catastrophic failures but at loads greater than reported under normal masticatory function.

The Use of 3D Printed Tooth Preparation to Assist in Teaching and Learning in Preclinical Fixed Prosthodontics Courses.

Tooth preparation for fixed dental prostheses is not an easy procedure to understand spatially, especially for first-year dental students. This technical report describes an innovative technique for assisting learning in preclinical fixed prosthodontics courses. Ideal full-contour tooth preparations are digitally scanned and 3D printed to the exact specifications of the ideal preparation. Students and faculty use these printed tooth preparations as teaching and learning tools to facilitate in 3D visualization for fixed prosthodontics courses.

In vitro 3D and gravimetric analysis of removed tooth structure for complete and partial preparations.

PURPOSE: To quantify and to compare a gravimetric and three-dimensional (3D) analysis of the removed tooth structure for different complete crown preparations. METHODS: A total of 80 molar resin teeth and 8 preparation finishing lines were chosen: 1 for metal ceramic crowns (MCC); 3 for zirconia all-ceramic crowns: knife edge (ZirKnE), chamfer (ZirCha), and shoulder (ZirSho); 4 for lithium disilicate: light chamfer (LDLCha), chamfer (LDCha), shoulder (LDSho) and table top. Teeth were individually weighed to high precision and then prepared following the preparation guidelines. The teeth were reweighed after preparation, and the amount of structural reduction was calculated. In addition, all teeth were scanned before and after preparation, and the 3D volume of removed dental tissue was calculated, superimposing the two .stl files, as a difference of the volumes before and after the preparation. Kruskal-Wallis statistical analysis was carried out to determine significant differences among the groups with a significance level of p<0.05. RESULTS: Both analyses showed that LDLCha, ZirKnE and table-top preparations produced the smallest amount of removed structure, whereas the preparations for MCC, ZirSho and LDSho were more destructive. For MCC, 2.6 times more tooth structure must be removed than for table top. ZirKnE was 17.82% and LDLCha was 21.51% more conservative than MCC. The data obtained through the volumetric method were similar with those obtained by gravimetric analysis. CONCLUSIONS: ZirKnE, LDLCha, and table-top preparations produced the least amount of tooth tissue removal. Three-dimensional volumetric analysis can be a possible alternative to gravimetric analysis.

Reabilitação com coroas metal free em dentes anteriores traumatizados e com rizogênese incompleta: relato de caso / Rehabilitation with metal free crowns in traumatized anterior teeth with incomplete rhizogenesis: case report

Objetivo: rizogênese incompleta refere-se a dentes permanentes em que não houve a formação completa do ápice radicular, ocasionando perda da vitalidade pulpar e, consequentemente, incapacidade da bainha epitelial de Hertwig para induzir a formação completa da raiz. Devido ao traumatismo e escurecimento dental, se faz necessário em certos casos a confecção de coroas em porcelana pura para reabilitar a paciente em estética e função. O presente trabalho tem como objetivo demonstrar um caso de reabilitação estética e funcional em dente com rizogênese incompleta, onde se consideraram as perdas estruturais e alteração de cor, para que seja possível estabelecer o tratamento mais adequado. Relato de caso: paciente de 16 anos, gênero feminino, atendida na Clínica de Odontologia de uma instituição privada, insatisfeita com a estética do seu dente devido ao escurecimento do elemento 21, pois quando tinha 5 anos o dente foi traumatizado juntamente com o elemento 11. O plano de tratamento adotado para ambos os elementos foi a confecção de peças protéticas em porcelana e cimentação. Considerações finais: esse caso demonstrou que a confecção de coroas estéticas em porcelana é considerada uma boa conduta na rotina clínica em casos de escurecimento dental, devolvendo estética e função para o paciente.(AU)

Objective: incomplete rhizogenesis refers to permanent teeth with incomplete formation of the root apex, causing loss of pulp vitality and the consequent inability of the Hertwig epithelial sheath to induce complete root formation. Due to dental trauma and darkening, some cases require the production of pure porcelain crowns to rehabilitate the aesthetics and function of patients. The present study aims to show a case of aesthetic and functional rehabilitation in a tooth with incomplete rhizogenesis, in which structural losses and color change were considered to establish the most appropriate treatment. Case report: a 16-year-old female patient treated at the Dental Clinic of a private institution. The patient was not satisfied with the aesthetics of her tooth due to the darkening of element 21, because at 5 years old the tooth was traumatized along with element 11. The treatment used for both elements was the production of prosthetic porcelain crowns and cementation. Final considerations: this case showed that the production of aesthetic porcelain crowns is considered a good conduct in the clinical routine in cases of tooth darkening, returning aesthetics and function to the patient.(AU)

Nonretentive Bonded Ceramic Partial Crowns: Concept and Simplified Protocol for Long-lasting Dental Restorations.

PURPOSE: Adhesively luted partial ceramic crowns have been documented to be clinically more durable than direct composite restorations when minimally invasively restoring large defects (replacing two cusps or more) in posterior teeth. The clinical longevity of such restorations is largely determined by the tooth-preparation design, material selection and adhesive luting procedure. The most frequently recorded failure in medium- to long-term clinical trials is fracture of the restoration. The clinical protocol of adhesively luted partial ceramic crowns can be optimized by taking the etiology of these restoration fractures into account. In this article, a simplified nonretentive bonded ceramic partial crown concept is presented that aims to achieve an adhesively luted ceramic restoration - composite cement - residual tooth structure biomechanical unit that maximally resists functional aging. Therefore, the three primary components of the bonded restoration-cement-tooth complex must function in synergy. Methods, Results and Discussion: The clinical protocol starts with a tooth preparation designed to optimally absorb chewing stress. A stable, internally rounded and gently sloping tooth-preparation design with all outer margins inclined towards the tooth center assures a favorable and homogenous stress distribution with low cyclic fatigue subjected to the adhesive interface. This preparation form additionally enables the dental technician to fabricate a well-seating and -fitting ceramic restoration of uniform thickness. As restoration material, monolithic lithium-disilicate glass ceramic is sufficiently strong for the partial crown indication and preferred in order to decrease the fracture risk. Clinically essential for a long-lasting restoration is the optimal bond that can be obtained by combined micromechanical interlocking and chemical bonding of composite cement to hydrofluoric acid-etched and silanized glass ceramic. CONCLUSION: The clinical effectiveness of this nonretentive bonded ceramic partial crown concept is confirmed by the overall high success rate as well as the very low fracture and debonding rate, as was recorded in long-term clinical trials.

Digital evaluation of marginal and internal fit of single-crown fixed dental prostheses.

The present study used a new, digitized version of the impression replica technique, namely the dual-scan technique, to evaluate the adaptation of single-crown fixed dental prostheses (FDPs). Scans of the bare master model and of the master model with a silicone layer representing the cement layer were superimposed and analyzed using designated software. Single crowns produced using the lost-wax metal casting technique were included. The cement space of the band width, 0.5-1.0 mm from the preparation margin (marginal fit), was smallest for crowns made from laser-sintered cobalt-chromium. The internal fit in both mesial-distal and buccal-palatal directions was statistically significantly better for crowns made using the conventional lost-wax metal casting technique than for crowns produced using computer-aided design/computer-aided manufacturing (CAD/CAM). Fixed dental prostheses produced by milled cobalt-chromium had the loosest internal fit. The results agree with those of our previous study of the same test specimens, in which the triple-scan method was used, and imply that the dual-scan method is well suited for adaptation studies.

Effect of preparation design on marginal and internal adaptation of translucent zirconia laminate veneers.

This study investigated the effect of preparation design on the marginal and internal adaptation of laminate veneers (LVs) fabricated from translucent zirconia. Thirty-three resin teeth were prepared for LVs of three designs: window preparation (WP); incisal shoulder preparation (ISP); and incisal palatal chamfer preparation (IPP). Marginal adaptation was evaluated by measuring the vertical discrepancy between the LV margin and the finish line at 60 points. The internal adaptation was assessed by measuring the internal space width as the distance between the LV and the tooth at cervical, central, and incisal sites after sectioning. At the incisal, mesial, and distal sites, mean marginal discrepancies were significantly lower in the WP group than in the other two groups; the IPP group had the highest marginal discrepancies. At incisal sites, the median internal space was significantly higher in the IPP group than in the WP and ISP groups and higher in the ISP group than in the WP group. At the incisal site, marginal and internal adaptations were better for the non-overlap translucent zirconia LV design (WP) than for the overlap designs (ISP and IPP). The characteristics of the translucent zirconia LVs used in the present study indicate acceptable clinical performance.

Effect of cavity design on the fracture resistance of zirconia onlay ceramics.

OBJECTIVE: The purpose of this study was to evaluate the fracture resistance and failure modes of onlay restorations prepared with different preparation designs. MATERIALS AND METHODS: A total of 42 extracted, mandibular first molars (36, 46) were used and divided into six groups according to preparation design, as follows 1A: Anatomic preparation of cusps/rounded shoulder margin/occlusal groove; 1B: Flat preparation of cusps/rounded shoulder margin/occlusal groove; 2A: Anatomical preparation of cusps/occlusal groove; 2B: Flat preparation of cusps/occlusal groove; 3A: Complete anatomical reduction of cusps/rounded shoulder margin; 3B: Complete flat reduction of cusps/rounded shoulder margin groups; intact tooth: No preparation. Onlays were constructed with 0.5-mm copings of Zirconia ceramic. The copings were veneered with porcelain (IPS e. max Ceram). All samples were subjected to fracture resistance testing. Data were analyzed with Kruskal-Wallis and Bonferroni-Dunn tests. RESULTS: Fracture resistance varied significantly according to preparation design. Among the anatomic occlusal preparation designs, fracture resistance was significantly lower in Group 3 when compared to Groups 1 and 2 (P < 0.05). Among the flat occlusal preparation designs, fracture resistance was significantly higher in Group 1 when compared to Groups 2 and 3 (P < 0.05). CONCLUSION: Preparation design affected the fracture resistance of onlay restorations. Cavities with flat occlusal preparation designs, a groove and shoulder margins (1B) resulted in the highest fracture resistance, whereas teeth prepared with a complete reduction of cusps and shoulder margins (3A) had the lowest fracture resistance.