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2.
Radiography (Lond) ; 30(4): 1210-1218, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38905765

RESUMO

INTRODUCTION: Evidence based practice relies on availability of research evidence mostly through peer-reviewed journal publications. No consensus currently exists on the best hierarchy of research evidence, often categorised by the adopted research designs. Analysing the prevalent research designs in radiography professional journals is one vital step in considering an evidence hierarchy specific to the radiography profession and this forms the aim of this study. METHODS: Bibliometric data of publications in three Radiography professional journals within a 10-year period were extracted. The Digital Object Identifier were used to locate papers on publishers' websites and obtain relevant data for analysis. Descriptive analysis using frequencies and percentages were used to represent data while Chi-square was used to analyse relationship between categorical variables. RESULTS: 1830 articles met the pre-set inclusion criteria. Quantitative descriptive studies were the most published design (26.6%) followed by non-RCT experimental studies (18.7%), while Randomised Controlled Trials (RCT) were the least published (1.0%). Systematic reviews (42.9%) showed the highest average percentage increase within the 10-year period, however RCTs showed no net increase. Single-centre studies predominated among experimental studies (RCT = 88.9%; Non-RCT = 95%). Author collaboration across all study designs was notable, with RCTs showing the most (100%). Quantitative and qualitative studies comparatively had similar number of citations when publication numbers were matched. Quantitative descriptive studies had the highest cumulative citations while RCTs had the least. CONCLUSION: There is a case to advocate for more study designs towards the peak of evidence hierarchies such as systematic reviews and RCT. Radiography research should be primarily designed to answer pertinent questions and improve the validity of the profession's evidence base. IMPLICATION FOR PRACTICE: The evidence presented can encourage the adoption of the research designs that enhances radiography profession's evidence base.


Assuntos
Bibliometria , Publicações Periódicas como Assunto , Radiologia , Projetos de Pesquisa , Humanos , Radiografia/estatística & dados numéricos
3.
Radiat Prot Dosimetry ; 200(8): 763-769, 2024 Jun 03.
Artigo em Inglês | MEDLINE | ID: mdl-38712384

RESUMO

Veterinary practitioners and other personnel involved in the examination are exposed to ionizing radiation while performing portable radiographs on horses. An online survey was distributed to all Veterinary Council of Ireland-registered practices where the self-reported practice profile is at least 20% equine work. The survey contained questions relating to radiation safety training, protocols, personal dosimetry and lead protection usage, repeat exposures, sedation, and personnel roles during the examination. The aim of the survey was to document the current radiation safety practices of equine veterinary practitioners during portable radiography. The results showed that although adherence to guidance set out by the Environmental Protection Agency (EPA) is reasonably good, compliance rates can be improved. Personal dosemeter usage and repeat rate reduction could particularly benefit from further improvement. This is of the utmost importance in ensuring that occupational radiation exposure to veterinary practitioners is kept to an absolute minimum during their daily practice.


Assuntos
Exposição Ocupacional , Proteção Radiológica , Irlanda , Cavalos , Animais , Exposição Ocupacional/análise , Exposição Ocupacional/prevenção & controle , Humanos , Inquéritos e Questionários , Radiografia/estatística & dados numéricos , Radiografia/normas , Radiografia/efeitos adversos , Médicos Veterinários , Doses de Radiação , Exposição à Radiação/análise
4.
Radiography (Lond) ; 30(3): 964-970, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38657390

RESUMO

INTRODUCTION: Non-medical professionals in the United Kingdom (UK) have been granted prescribing rights to improve patient care quality and cost-effectiveness. There is limited evidence on how therapeutic radiographer prescribers have impacted medicine management or patient services. METHODS: An online survey was conducted amongst non-medical prescribing therapeutic radiographers in the UK between 2019 and 2022. The study teams initially analysed the individual data sets, subsequently combined, and secondary analysis was performed to provide a UK perspective, to understand the services provided and identify areas for improvement. Data was analysed using descriptive statistics from Microsoft Excel® and SPSS®. RESULTS: 74 non-medical prescribing therapeutic radiographers who were predominantly over 40 years old and in full-time work participated. The main job categories were consultant radiographers (n = 23, 31.1%) and advanced practice practitioners (n = 18, 24.3%). Many use their prescribing qualifications (87.5%, n = 62), issuing a mean of 15 independent and seven items by supplementary and prescribing per week. Most received assessment and diagnostic skills training before prescribing courses (91.6%, n = 67). Respondents prescribed from a median of six areas, with the highest being in GI (82%), skin (68%), infections (58%), urinary tract disorders (55%) and ear, nose, and oropharynx conditions (54%). CONCLUSION: This study presents the first report on therapeutic radiographers prescribing in the UK, offering insights into current practices and highlighting the success of non-medical prescribing. Therapeutic radiographers' roles continue to expand into advanced practice and medicine-prescribing responsibilities, contributing to holistic and patient-centred care. IMPLICATIONS FOR PRACTICE: The results are relevant for nations grappling with oncology workforce shortages and contemplating similar roles for therapeutic radiographers. The study can be a valuable resource for policymakers and healthcare organisations worldwide.


Assuntos
Radiografia , Humanos , Reino Unido , Inquéritos e Questionários , Feminino , Masculino , Adulto , Pessoa de Meia-Idade , Radiografia/estatística & dados numéricos , Prescrições , Pessoal Técnico de Saúde
5.
J Pediatr Orthop ; 44(6): e530-e535, 2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38512220

RESUMO

OBJECTIVE: Supracondylar humerus (SCH) fractures are common among pediatric patients, with the severity categorized using the Gartland classification system. Type 1 SCH fractures are nondisplaced and treated with immobilization, while more displaced fractures require surgery. The need for follow-up radiographs, particularly for type 1 fractures, is an area where evidence is lacking. This study investigates the clinical value and financial implications of follow-up radiographs for type 1 SCH fractures, hypothesizing that they do not alter clinical management and, therefore, represent an unnecessary expense. METHODS: This retrospective cohort study, approved by the Institutional Review Board, focused on patients under 18 with nondisplaced SCH fractures treated nonoperatively. One hundred one type 1 SCH fractures, in which the fracture was visible on presenting radiographs, were chosen from patients presenting between January 2021 and December 2022. Charts were reviewed for demographic information, time of cast removal, and complications. A pediatric orthopaedic surgeon and orthopaedic resident reviewed the radiographs to confirm the injury to be a type 1 SCH fracture. RESULTS: Among the 101 patients, after the initial presentation, 79 attended an interim visit and 101 attended a "3-week follow-up" at an average of 23 days postinjury. All patients underwent radiographs during these visits for a total of 180 radiographs after confirmation of type 1 SCH fracture. No changes in management resulted from follow-up radiographs. One instance of refracture was noted ~3 months after cast removal. There were 180 superfluous follow-up radiographs taken at subsequent clinic visits. The total charge for these radiographs was $76,001.40, averaging $752.49 per patient. CONCLUSION: Follow-up radiographs for type 1 SCH fractures did not lead to changes in clinical management, aligning with previous findings in more severe SCH fractures. This approach can reduce costs, radiation exposure, and clinic time without compromising patient care. The study can reassure providers and parents about the lack of necessity for follow-up radiographs to document healing. LEVEL OF EVIDENCE: Level-IV.


Assuntos
Fraturas do Úmero , Radiografia , Humanos , Estudos Retrospectivos , Fraturas do Úmero/diagnóstico por imagem , Fraturas do Úmero/terapia , Masculino , Feminino , Radiografia/métodos , Radiografia/estatística & dados numéricos , Criança , Pré-Escolar , Seguimentos , Lactente , Adolescente
6.
J Med Imaging Radiat Sci ; 55(2): 232-243, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38403518

RESUMO

INTRODUCTION: Various national solutions have been considered and implemented to address the factors which limit radiographer engagement in conducting research. Nevertheless, national literature continues to suggest that radiographer engagement in research remains low. The aim of this study was to extend the existing evidence base by conducting an international survey to assess diagnostic radiographers and therapeutic radiographers involvement with, barriers to and support mechanisms for research. METHODS: Data collection was obtained via an online questionnaire which was distributed by the International Society of Radiographers and Radiologic Technologists (ISRRT). The study population included an international sample of qualified diagnostic radiographers and therapeutic radiographers across clinical and academic contexts in a variety of different roles such as clinical practice, management, education and research. RESULTS: In total, 420 diagnostic radiographers and therapeutic radiographers completed the survey. Multiple reasons were identified that were considered to inhibit respondents from conducting research. 69.3% indicated a combination of reasons for lack of engagement with research, rather than one single issue. Examples of reasons include: lack of time, insufficient research funding, limited research expertise, and lack of a suitable mentorship scheme. CONCLUSION: A minor segment of survey respondents indicated involvement in research activity. Lack of dedicated time to research, mentors, and funding were among the main barriers to conduct research. Further research is required to explore what solutions are available to overcoming the barriers.


Assuntos
Tecnologia Radiológica , Humanos , Inquéritos e Questionários , Feminino , Masculino , Adulto , Internacionalidade , Pessoa de Meia-Idade , Pesquisa Biomédica , Pessoal Técnico de Saúde , Radiografia/estatística & dados numéricos
7.
Spine Deform ; 12(3): 755-761, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38336942

RESUMO

INTRODUCTION: Spinal measurements play an integral role in surgical planning for a variety of spine procedures. Full-length imaging eliminates distortions that can occur with stitched images. However, these images take radiologists significantly longer to read than conventional radiographs. Artificial intelligence (AI) image analysis software that can make such measurements quickly and reliably would be advantageous to surgeons, radiologists, and the entire health system. MATERIALS AND METHODS: Institutional Review Board approval was obtained for this study. Preoperative full-length standing anterior-posterior and lateral radiographs of patients that were previously measured by fellowship-trained spine surgeons at our institution were obtained. The measurements included lumbar lordosis (LL), greatest coronal Cobb angle (GCC), pelvic incidence (PI), coronal balance (CB), and T1-pelvic angle (T1PA). Inter-rater intra-class correlation (ICC) values were calculated based on an overlapping sample of 10 patients measured by surgeons. Full-length standing radiographs of an additional 100 patients were provided for AI software training. The AI algorithm then measured the radiographs and ICC values were calculated. RESULTS: ICC values for inter-rater reliability between surgeons were excellent and calculated to 0.97 for LL (95% CI 0.88-0.99), 0.78 (0.33-0.94) for GCC, 0.86 (0.55-0.96) for PI, 0.99 for CB (0.93-0.99), and 0.95 for T1PA (0.82-0.99). The algorithm computed the five selected parameters with ICC values between 0.70 and 0.94, indicating excellent reliability. Exemplary for the comparison of AI and surgeons, the ICC for LL was 0.88 (95% CI 0.83-0.92) and 0.93 for CB (0.90-0.95). GCC, PI, and T1PA could be determined with ICC values of 0.81 (0.69-0.87), 0.70 (0.60-0.78), and 0.94 (0.91-0.96) respectively. CONCLUSIONS: The AI algorithm presented here demonstrates excellent reliability for most of the parameters and good reliability for PI, with ICC values corresponding to measurements conducted by experienced surgeons. In future, it may facilitate the analysis of large data sets and aid physicians in diagnostics, pre-operative planning, and post-operative quality control.


Assuntos
Algoritmos , Inteligência Artificial , Radiografia , Humanos , Radiografia/métodos , Radiografia/estatística & dados numéricos , Reprodutibilidade dos Testes , Adulto , Feminino , Masculino , Coluna Vertebral/diagnóstico por imagem , Coluna Vertebral/cirurgia , Lordose/diagnóstico por imagem , Pessoa de Meia-Idade , Variações Dependentes do Observador , Curvaturas da Coluna Vertebral/diagnóstico por imagem , Curvaturas da Coluna Vertebral/cirurgia
8.
Ethiop J Health Sci ; 33(4): 641-648, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38784216

RESUMO

Background: Scoliosis is an abnormal side-to-side spinal curve of greater than or equal to 100 Cobb angle. It is the most common spinal deformity in children and adolescents. Epidemiological evidence about scoliosis is scarce in Africa, including Ethiopia. This study was aimed at determining the prevalence of scoliosis among adolescents and analysing its association with age and sex using plain chest radiographs obtained for non-spinal reasons in Tikur Anbessa Specialized Hospital. Method: All non-tilted, non-rotated, and non-poorly penetrated digital plain chest radiographs of adolescents aged 10 to 19 years obtained at Tikur Anbessa Specialized Hospital between January 1 and December 31, 2019, were measured for the coronal Cobb angle. The data were cleaned, coded, and entered into SPSS version 26 for analysis. Chi-square, and linear regression, and logistic regression analyses were also carried out to evaluate the effect of sex and age on scoliosis. Results: The Cobb angles of 1,369 posteroanterior chest radiographs of adolescents were measured. Thirty (2.2%, 95% CI: 1.4%, 3.0%) of these were found to have scoliosis. The mean coronal Cobb angle was 2.270±6.320. There was no statistically significant difference between the prevalence of scoliosis in boys (2.21%) and girls (2.17%) (X2=0.003, P=0.954). Likewise, age did not show any statistically significant difference in the prevalence of scoliosis (X2=2.655, P=0.265). Conclusion: This study revealed that incidental finding of adolescent scoliosis in plain chest radiographs is common. Further study using whole spine radiography should be carried out to determine the true general population prevalence of scoliosis in Ethiopia.


Assuntos
Escoliose , Humanos , Escoliose/epidemiologia , Escoliose/diagnóstico por imagem , Adolescente , Etiópia/epidemiologia , Masculino , Feminino , Prevalência , Criança , Adulto Jovem , Radiografia Torácica/métodos , Radiografia/métodos , Radiografia/estatística & dados numéricos , Fatores Sexuais , Hospitais Especializados/estatística & dados numéricos
9.
Br J Radiol ; 95(1130): 20210700, 2022 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-34898256

RESUMO

OBJECTIVE: The purpose of this study was to explore the feasibility to determine regional diagnostic reference levels (RDRLs) for paediatric conventional and CT examinations using the European guidelines and to compare RDRLs derived from weight and age groups, respectively. METHODS: Data were collected from 31 hospitals in 4 countries, for 7 examination types for a total of 2978 patients. RDRLs were derived for each weight and age group, respectively, when the total number of patients exceeded 15. RESULTS: It was possible to derive RDRLs for most, but not all, weight-based and age-based groups for the seven examinations. The result using weight-based and age-based groups differed substantially. The RDRLs were lower than or equal to the European and recently published national DRLs. CONCLUSION: It is feasible to derive RDRLs. However, a thorough review of the clinical indications and methodologies has to be performed previous to data collection. This study does not support the notion that DRLs derived using age and weight groups are exchangeable. ADVANCES IN KNOWLEDGE: Paediatric DRLs should be derived using weight-based groups with access to the actual weight of the patients. DRLs developed using weight differ markedly from those developed with the use of age. There is still a need to harmonize the method to derive solid DRLs for paediatric radiological examinations.


Assuntos
Níveis de Referência de Diagnóstico , Guias de Prática Clínica como Assunto , Radiografia , Fatores Etários , Peso Corporal , Criança , Pré-Escolar , Europa (Continente) , Estudos de Viabilidade , Cabeça/diagnóstico por imagem , Articulação do Quadril/diagnóstico por imagem , Humanos , Lactente , Recém-Nascido , Pelve/diagnóstico por imagem , Exposição à Radiação , Radiografia/estatística & dados numéricos , Radiografia Abdominal/estatística & dados numéricos , Radiografia Torácica/estatística & dados numéricos , Tomografia Computadorizada por Raios X/estatística & dados numéricos
10.
Br J Radiol ; 95(1130): 20210881, 2022 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-34919419

RESUMO

OBJECTIVES: Radiography remains the mainstay of diagnostic and follow-up imaging. In view of the risks and the increasing use of ionizing radiation, dose reduction is a key issue for research and development. The introduction of digital radiography and the associated access to image postprocessing have opened up new opportunities to minimize the radiation dosage. These advances are contingent upon quality controls to ensure adequate image detail and maintenance of diagnostic confidence. The purpose of this study was to investigate the clinical applicability of postprocessed low-dose images in skeletal radiography. METHODS: In our study setting, the median radiation dose for full dose X-rays was 9.61 dGy*cm2 for pelvis, 1.20 dGy*cm2 for shoulder and 18.64 dGy*cm2 for lumbar spine exams. Based on these values, we obtained 200 radiographs for each anatomic region in four consecutive steps, gradually reducing the dose to 84%, 71%, 60% and 50% of the baseline using an automatic exposure control (AEC). 549 patients were enrolled for a total of 600 images. All X-rays were postprocessed with a spatial noise reduction algorithm. Two radiologists assessed the diagnostic value of the radiographs by rating the visualization of anatomical landmarks and image elements on a five-point Likert scale. A mean-sum score was calculated by averaging the two reader's total scores. Given the non-parametric distribution, we used the Mann-Whitney U test to evaluate the scores. RESULTS: Median dosage at full dose accounted for 38.4%, 48 and 53.2% of the German reference dose area product for shoulder, pelvis and lumbar spine, respectively. The applied radiation was incrementally reduced to 21.5%, 18.4% and 18.7% of the respective reference value for shoulder, pelvis and lumbar spine. Throughout the study, we observed an estimable tendency of superior quality at higher dosage in overall image quality. Statistically significant differences in image quality were restricted to the 50% dose groups in shoulder and lumbar spine images. Regardless of the applied dosage, 598 out of 600 images were of sufficient diagnostic value. CONCLUSION: In digital radiography image postprocessing allows for extensive reduction of radiation dosage. Despite a trend of superior image detail at higher dose levels, overall quality and, more importantly, diagnostic utility of low-dose images was not significantly affected. Therefore, our results not only confirm the clinical utility of postprocessed low-dose radiographs, but also suggest a widespread deployment of this advanced technology to ensure further dose limitations in clinical practice. ADVANCES IN KNOWLEDGE: The diagnostic image quality of postprocessed skeletal radiographs is not significantly impaired even after extensive dose reduction by up to 20% of the reference value.


Assuntos
Vértebras Lombares/diagnóstico por imagem , Ossos Pélvicos/diagnóstico por imagem , Doses de Radiação , Intensificação de Imagem Radiográfica , Ombro/diagnóstico por imagem , Algoritmos , Osso e Ossos/diagnóstico por imagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Exposição à Radiação/prevenção & controle , Intensificação de Imagem Radiográfica/normas , Radiografia/estatística & dados numéricos , Valores de Referência , Estatísticas não Paramétricas
11.
Am J Otolaryngol ; 43(1): 103237, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34560599

RESUMO

OBJECTIVE: Bone impaction (BI) is a common cause for emergency room visits. Among foreign bodies, fish bone is considered the most common. The sensitivity of symptoms in predicting BI is relatively low, making imaging a central tool to aid diagnosis. Current imaging practices include both neck plain film radiography and none-contrast CT scans of the neck. We evaluated the accuracy of neck plain film radiography and CT scans of the neck for the diagnosis of BI. METHODS: Retrospective review of all patients who presented to the emergency room between 2009 and 2016 with a suspicious history of BI whom underwent plain film neck radiography or CT. All Images were reviewed by two neuro-radiologist blinded to the clinical symptoms and findings. Symptoms, clinical findings and images results were compared to the final diagnosis. RESULTS: 89 patients (30.7%), out of 290 patients who presented with complaints of BI, were diagnosed with BI. Mean age was 44.7 years old. Plain film neck radiography failed to predict BI (sen. 14.4%, spe 89.8% accuracy 63.2%), neck CT has an improved accuracy and sensitivity in locating BI (sen. 83.3%, spe. 94.1% accuracy 92.5%). Interobserver agreement between the two neuro-radiologists was moderate (0.46) and substantial (0.77) in neck radiography and CT images, respectively. Neck radiography missed 60 (out of 61) oropharyngeal BI's. CONCLUSION: Neck radiography has high inter-observer variability and low sensitivity for the diagnosis of BI. Neck CT should be the first imaging modality in patients with suspicious complaints for BI and negative physical exam.


Assuntos
Corpos Estranhos/diagnóstico por imagem , Cervicalgia/diagnóstico por imagem , Pescoço/diagnóstico por imagem , Radiografia/estatística & dados numéricos , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Adulto , Animais , Osso e Ossos/diagnóstico por imagem , Diagnóstico Diferencial , Feminino , Peixes , Corpos Estranhos/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Cervicalgia/etiologia , Variações Dependentes do Observador , Radiografia/métodos , Sensibilidade e Especificidade , Tomografia Computadorizada por Raios X/métodos
12.
Comput Math Methods Med ; 2021: 9572363, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34899972

RESUMO

OBJECTIVE: To analyse the X-ray and computed tomography (CT) findings of 128 patients with sports-related knee fractures and to improve the diagnosis rate based on the existing methods of diagnosis of sports knee fractures on X-ray and CT images. METHOD: In this study, we retrospectively analyse the medical records of 128 cases of sports-related fractures in the hospital, analyse the results of X-ray examination and CT imaging of patients with sports knee fractures, and compare the results obtained by the two examination methods, while referring to MRI images performed. RESULTS: CT examination of knee fractures, tibial plateau fractures, and knee joint free body results were compared with X-ray results (P < 0.05), while CT examination of patella fractures and X-ray results were compared. The difference was not statistically significant (P > 0.05). CONCLUSION: For imaging examination of knee fractures, a single ordinary X-ray or CT scan should be selected according to the specific situation of the patient. For patients with suspected unstable fractures, when the patient's informed consent and the condition are not allowed, ordinary X-ray film combined with CT examination is used to improve the accuracy of diagnosis and avoid the existence of hidden fractures, resulting in medical accidents.


Assuntos
Traumatismos em Atletas/diagnóstico por imagem , Fraturas Ósseas/diagnóstico por imagem , Traumatismos do Joelho/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Adolescente , Adulto , Idoso , Biologia Computacional , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Imagem Multimodal/métodos , Imagem Multimodal/estatística & dados numéricos , Radiografia/métodos , Radiografia/estatística & dados numéricos , Estudos Retrospectivos , Fraturas da Tíbia/diagnóstico por imagem , Tomografia Computadorizada por Raios X/estatística & dados numéricos , Adulto Jovem
13.
Arq. bras. med. vet. zootec. (Online) ; 73(6): 1431-1435, Nov.-Dec. 2021. tab, ilus
Artigo em Inglês | LILACS, VETINDEX | ID: biblio-1355672

RESUMO

A radiologia é uma importante ferramenta complementar para o diagnóstico de diversas afecções em diferentes espécies. O uso de exames complementares na medicina de animais silvestres, em especial o exame de imagem, traz inúmeras informações acerca do paciente. Este trabalho apresenta os dados obtidos por meio de um levantamento dos exames radiográficos realizados em animais silvestres entre os anos de 2017 e 2020, no Laboratório de Diagnóstico de Imagem e Cardiologia (LADIC), do Hospital de Clínicas Veterinárias da Universidade Federal de Pelotas (HCV/UFPel). Ao todo, foram avaliados 464 prontuários, sendo 293 (63,1%) de aves, 135 (29,1%) de mamíferos e 36 (7,8%) de répteis. As alterações mais encontradas nos exames radiológicos foram fratura de membros torácicos para as duas primeiras classes, e pneumonia para a última.(AU)


Assuntos
Animais , Pneumonia/diagnóstico por imagem , Traumatismos Torácicos/diagnóstico por imagem , Animais Selvagens/lesões , Brasil , Radiografia/veterinária , Radiografia/estatística & dados numéricos
14.
Isr Med Assoc J ; 23(10): 646-650, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34672447

RESUMO

BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory and destructive joint disease with the presence of autoantibodies, rheumatoid factor (RF), and anti-citrullinated protein antibodies (ACPA). The presence of RF or ACPA predicts RA severity. Data on the influence of ACPA titer on RA course are limited. OBJECTIVES: To determine the correlation between ACPA titers at the time of RA diagnosis to RA features and severity during 3 years of follow-up. METHODS: We performed a retrospective study of RA patients treated at our institution during the years 2006-2015 with known ACPA titers at RA diagnosis who completed at least 3 years of follow-up. Patients (N=133) were divided according to ACPA titer: seronegative (< 15 U/ml, n=55), weakly positive (15-49 U/ml, n=18), moderately positive (50-300 U/ml, n=29), and strongly positive (> 300 U/ml, n=31). Patient data, including disease activity score (DAS28), bone erosion on hand and/or foot X-rays, treatments with corticosteroids and disease-modifying-anti-rheumatic drugs (DMARDs), and hospitalizations, were recorded. Chi-square and Mann-Whitney method were used for statistical analysis. P < 0.05 was considered as statistically significant. RESULTS: Male gender, smoking, and RF positivity correlated with ACPA positivity and higher ACPA titers. There was no correlation between ACPA titer and the variables defined as representing RA severity: higher DAS28, bone erosions, hospitalizations, need for corticosteroids, and conventional and biological DMARDs. CONCLUSIONS: Titer of ACPA was not identified as a predictive factor for RA severity.


Assuntos
Corticosteroides/uso terapêutico , Anticorpos Antiproteína Citrulinada/sangue , Antirreumáticos/uso terapêutico , Artrite Reumatoide , Monitorização Imunológica , Radiografia , Artrite Reumatoide/diagnóstico , Artrite Reumatoide/tratamento farmacológico , Artrite Reumatoide/epidemiologia , Artrite Reumatoide/imunologia , Correlação de Dados , Progressão da Doença , Feminino , Humanos , Israel/epidemiologia , Masculino , Pessoa de Meia-Idade , Monitorização Imunológica/métodos , Monitorização Imunológica/estatística & dados numéricos , Resultados Negativos , Gravidade do Paciente , Valor Preditivo dos Testes , Prognóstico , Radiografia/métodos , Radiografia/estatística & dados numéricos , Estudos Retrospectivos , Fator Reumatoide/sangue , Índice de Gravidade de Doença
15.
Br J Radiol ; 94(1127): 20210331, 2021 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-34541860

RESUMO

OBJECTIVE: To compare age groupings versus weight groupings in the calculation of typical air kerma area product (PKA) values in paediatric X-ray exams of chest and abdomen in our hospital. METHODS: Data were analysed from 687 abdominal and 1374 chest X-ray examinations. The PKA of exams was extracted with Radimetrics, and patient weights were collected from electronic records. Data were organised in different age groups and typical PKA values were estimated. The process was repeated by organising data in different weight groups. RESULTS: Typical PKA values for the four younger age groups (<1m, 1m - < 4y, 4y - < 10y and 10y - < 14y) were comparable to typical values for their equivalent weight groups (<5 kg, 5-15 kg, 15-30 kg and 30-50 kg, respectively). However, typical PKA values at the late adolescent age group (14y - < 18y) were much lower than its equivalent weight group (>50 kg). CONCLUSIONS: Age and weight groupings were found at our site to be interchangeable for the calculation of typical paediatric PKA values. The only exception was the late adolescent group, whose weight distribution can account for the difference in typical PKA results within its equivalent weight group. ADVANCES IN KNOWLEDGE: In calculating typical PKA values for radiological paediatric body examinations, departments must ascertain if using age groups, which is typical practice, is equivalent to using weight groups. Otherwise, results may misrepresent local practice.


Assuntos
Abdome/diagnóstico por imagem , Doses de Radiação , Radiografia/métodos , Radiografia/estatística & dados numéricos , Tórax/diagnóstico por imagem , Distribuição por Idade , Fatores Etários , Peso Corporal , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Pediatria/métodos , Radiografia Torácica
16.
PLoS One ; 16(9): e0256849, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34469467

RESUMO

Radiologists can visually detect abnormalities on radiographs within 2s, a process that resembles holistic visual processing of faces. Interestingly, there is empirical evidence using functional magnetic resonance imaging (fMRI) for the involvement of the right fusiform face area (FFA) in visual-expertise tasks such as radiological image interpretation. The speed by which stimuli (e.g., faces, abnormalities) are recognized is an important characteristic of holistic processing. However, evidence for the involvement of the right FFA in holistic processing in radiology comes mostly from short or artificial tasks in which the quick, 'holistic' mode of diagnostic processing is not contrasted with the slower 'search-to-find' mode. In our fMRI study, we hypothesized that the right FFA responds selectively to the 'holistic' mode of diagnostic processing and less so to the 'search-to-find' mode. Eleven laypeople and 17 radiologists in training diagnosed 66 radiographs in 2s each (holistic mode) and subsequently checked their diagnosis in an extended (10-s) period (search-to-find mode). During data analysis, we first identified individual regions of interest (ROIs) for the right FFA using a localizer task. Then we employed ROI-based ANOVAs and obtained tentative support for the hypothesis that the right FFA shows more activation for radiologists in training versus laypeople, in particular in the holistic mode (i.e., during 2s trials), and less so in the search-to-find mode (i.e., during 10-s trials). No significant correlation was found between diagnostic performance (diagnostic accuracy) and brain-activation level within the right FFA for both, short-presentation and long-presentation diagnostic trials. Our results provide tentative evidence from a diagnostic-reasoning task that the FFA supports the holistic processing of visual stimuli in participants' expertise domain.


Assuntos
Competência Clínica/estatística & dados numéricos , Reconhecimento Visual de Modelos/fisiologia , Radiologistas/estatística & dados numéricos , Radiologia/estatística & dados numéricos , Córtex Visual/fisiologia , Adulto , Mapeamento Encefálico , Estudos de Casos e Controles , Feminino , Humanos , Internato e Residência/estatística & dados numéricos , Imageamento por Ressonância Magnética , Masculino , Estimulação Luminosa/métodos , Radiografia/estatística & dados numéricos , Radiologistas/educação , Radiologia/educação , Tempo de Reação/fisiologia , Fatores de Tempo , Córtex Visual/diagnóstico por imagem , Adulto Jovem
17.
Breast Cancer Res ; 23(1): 79, 2021 08 03.
Artigo em Inglês | MEDLINE | ID: mdl-34344426

RESUMO

BACKGROUND: Diagnostic ionizing radiation is a risk factor for breast cancer (BC). BC risk increases with increased dose to the chest and decreases with increased age at exposure, with possible effect modification related to familial or genetic predisposition. While chest X-rays increase the BC risk of BRCA1/2 mutation carriers compared to non-carriers, little is known for women with a hereditary predisposition to BC but who tested negative for a BRCA1 or BRCA2 (BRCA1/2) mutation. METHODS: We evaluated the effect of chest X-rays from diagnostic medical procedures in a dataset composed of 1552 BC cases identified through French family cancer clinics and 1363 unrelated controls. Participants reported their history of X-ray exposures in a detailed questionnaire and were tested for 113 DNA repair genes. Logistic regression and multinomial logistic regression models were used to assess the association with BC. RESULTS: Chest X-ray exposure doubled BC risk. A 3% increased BC risk per additional exposure was observed. Being 20 years old or younger at first exposure or being exposed before first full-term pregnancy did not seem to modify this risk. Birth after 1960 or carrying a rare likely deleterious coding variant in a DNA repair gene other than BRCA1/2 modified the effect of chest X-ray exposure. CONCLUSION: Ever/never chest X-ray exposure increases BC risk 2-fold regardless of age at first exposure and, by up to 5-fold when carrying 3 or more rare variants in a DNA repair gene. Further studies are needed to evaluate other DNA repair genes or variants to identify those which could modify radiation sensitivity. Identification of subpopulations that are more or less susceptible to ionizing radiation is important and potentially clinically relevant.


Assuntos
Neoplasias da Mama/etiologia , Predisposição Genética para Doença/genética , Radiografia/efeitos adversos , Adulto , Neoplasias da Mama/genética , Reparo do DNA/genética , Feminino , Genes BRCA1 , Genes BRCA2 , Humanos , Pessoa de Meia-Idade , Mutação , Radiografia/estatística & dados numéricos , Risco , Fatores de Risco , Adulto Jovem
18.
Medicine (Baltimore) ; 100(30): e26126, 2021 Jul 30.
Artigo em Inglês | MEDLINE | ID: mdl-34397682

RESUMO

ABSTRACT: It was reported imperative on cervical sagittal alignment reconstruction after anterior multilevel procedures with self-locked stand-alone cage (SSC) or anterior cage-with-plate (ACP) system multilevel while there was little knowledge about the relationship on cervical alignment and clinical outcomes.To identify the importance of cervical sagittal alignment after 3-level anterior cervical discectomy and fusion on cervical spondylotic myelopathy with SSC and ACP system.Seventy-seven patients with SSC system (SSC group) and 52 cases with ACP system (ACP group) from February 2007 to September 2013 were enrolled with well-matched demographics. Cervical alignment included C2-7 lordosis (CL), operated-segment cervical lordosis (OPCL), upper and lower adjacent-segment cervical lordosis, range of motion of upper and lower adjacent segment at preoperation, immediate postoperation, and the final follow-up. Clinical outcomes contained the neck disability index (NDI), the Japanese Orthopaedic Association (JOA) score, visual analogous scale (VAS) of arm and neck and adjacent segment degeneration (ASD). Patients were then divided into CL improved subgroup (IM subgroup) and non-improved subgroup (NIM subgroup).There were improvements on CL and OPCL in both groups. The change of CL and OPCL larger in ACP group (P < .05) but upper adjacent-segment cervical lordosis/lower adjacent-segment cervical lordosis and range of motion of upper adjacent segment/range of motion of lower adjacent segment were of no significance. NDI, JOA, and VAS got improvement in both groups at immediate postoperation and the final follow-up while ASD was in no difference between SSC and ACP group. A total of 80 patients (39 vs 41) acquired CL improvement with a larger population in ACP group. There were no differences on the rate of ASD, NDI, JOA, VAS, and their change between IM and NIM subgroup. The changes of CL were not correlated to NDI, JOA, VAS, and their change.SSC and ACP group both provide improved OPCL and efficacy on 3-level cervical spondylotic myelopathy with little impact on adjacent segment. The change of CL is not correlated to clinical outcomes.


Assuntos
Vértebras Cervicais/cirurgia , Radiografia/estatística & dados numéricos , Doenças da Medula Espinal/cirurgia , Fusão Vertebral/normas , Idoso , Vértebras Cervicais/fisiopatologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Radiografia/métodos , Estudos Retrospectivos , Doenças da Medula Espinal/diagnóstico por imagem , Doenças da Medula Espinal/fisiopatologia , Fusão Vertebral/métodos , Fusão Vertebral/estatística & dados numéricos , Resultado do Tratamento
19.
Trop Doct ; 51(3): 296-301, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34041979

RESUMO

There is a paucity of studies on the correlation between chest radiograph and ultrasound (US) in children. Our objective was to study the correlation between bedside chest radiograph and ultrasound findings in 413 children with 1002 episodes of chest radiograph and US enrolled for a prospective, double-blinded observational study in a multidisciplinary paediatric intensive care unit. Weighted κ statistic for agreement was different for right and left lungs and varied from 50% for left pleural effusion to 98% for right pneumothorax. Pulmonary oedema, pneumothorax and pleural effusion were diagnosed by ultrasound alone in a significantly higher number of patients as compared to chest radiograph (P = 0.001). Chest ultrasound is therefore deemed more sensitive than chest radiograph in detection of pleural effusion, pulmonary oedema and pneumothorax.


Assuntos
Pulmão/diagnóstico por imagem , Pneumotórax/diagnóstico por imagem , Sistemas Automatizados de Assistência Junto ao Leito , Radiografia/estatística & dados numéricos , Ultrassonografia/estatística & dados numéricos , Criança , Cuidados Críticos , Método Duplo-Cego , Humanos , Unidades de Terapia Intensiva Pediátrica , Derrame Pleural/diagnóstico por imagem , Estudos Prospectivos , Radiografia/métodos , Ultrassonografia/métodos
20.
Clin Orthop Relat Res ; 479(8): 1842-1848, 2021 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-33944807

RESUMO

BACKGROUND: Previous CT and cadaver studies have suggested that the external obturator footprint might be used as a landmark for stem depth in direct anterior THA. Instructions on where to template this structure with small variability in height have been developed but have not been tested in daily clinical practice. QUESTIONS/PURPOSES: In this study we sought to investigate the (1) usability, (2) accuracy, and (3) reliability of the external obturator footprint as a landmark for stem depth in direct anterior THA. METHODS: The distance between the superior border of the external obturator tendon and the shoulder of the stem was measured intraoperatively in all patients (n = 135) who underwent primary THA via a direct anterior approach performed by the senior author between November 2019 and October 2020. The landmark was considered useful when two of thre`e evaluators agreed that the intersection of the vertical line comprised of the lateral wall of the trochanteric fossa and the oblique line formed by the intertrochanteric crest was clearly visible on the preoperative planning radiograph, and when the landmark was furthermore identified with certainty during surgery. Accuracy was defined as the degree of agreement (categorical for thresholds of 2 and 5 mm, the latter representing the threshold for developing unphysiological gait parameters) between the intraoperative distance and radiographic distance as measured on intraoperative fluoroscopy images or postoperative radiographs, which were calibrated based on femoral head sizes in a software program commonly used for templating. Intrarater reliability was defined as the degree of agreement (categorical for thresholds of 1 mm, which we considered an acceptable measurement error) between the ratings of one observer, who measured the radiographic distance on two different occasions separated by a washout period of at least 2 weeks. Interrater reliability was defined as the degree of agreement (categorical for thresholds of 1 mm, which we considered an acceptable measurement error) between the ratings of three observers with varying levels of experience (a fellowship-trained hip surgeon, a hip surgery fellow, and a medical student). RESULTS: The landmark was considered useful in 77% (104 of 135) of patients who underwent direct anterior THA based on the observations that the trochanteric fossa was clearly visible on the planning radiograph in 117 patients and that the tendon was identified with certainty during surgery in 118 patients. There was good-to-excellent accuracy (intraclass correlation coefficient 0.75-087), and intrarater reliability (ICC 0.99) and interrater reliability (ICC 0.99) were both excellent. CONCLUSION: This clinical study showed that the external obturator footprint is a useful, accurate, and reliable landmark for stem depth in direct anterior THA. CLINICAL RELEVANCE: The external obturator landmark allows the surgeon to position the stem within a range of the templated depth that is beneath the threshold for the development of unphysiological gait parameters. Although strictly speaking it was found useful in 77% of patients in this study, we found that this percentage of usability can easily be improved to around 90% by providing the radiology lab technician with instructions to correct external rotation of the foot during the taking of the planning radiograph. Future studies could compare the established (in)equality in leg length in patients using the external obturator landmark with computer-assisted surgery.


Assuntos
Pontos de Referência Anatômicos/diagnóstico por imagem , Artroplastia de Quadril/métodos , Articulação do Quadril/diagnóstico por imagem , Radiografia/estatística & dados numéricos , Tendões/diagnóstico por imagem , Idoso , Pontos de Referência Anatômicos/cirurgia , Feminino , Fluoroscopia/métodos , Fluoroscopia/estatística & dados numéricos , Articulação do Quadril/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia/métodos , Reprodutibilidade dos Testes , Cirurgia Assistida por Computador/métodos
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