RESUMO
The Infusion Therapy Standards of Practice provide evidence-based recommendations for infusion and access device related care in any healthcare setting. Developed and published by the Infusion Nurses Society, the Standards have increased the frequency of the revision process from an every 5-year cycle to a 3-year cycle due to the growing base of literature and to deliver the most updated and current practice recommendations. This article provides an overview of the development process and a brief description of selected standards. Notably, a new standard entitled Home Infusion Therapy was added in this latest edition. The Standards are an essential reference that should be available to every home care agency that provides home infusion therapy.
Assuntos
Terapia por Infusões no Domicílio , Humanos , Terapia por Infusões no Domicílio/normas , Terapia por Infusões no Domicílio/enfermagem , Guias de Prática Clínica como Assunto , Serviços de Assistência Domiciliar/normasRESUMO
OBJECTIVES: To describe the experience of home antibiotic infusion therapy using elastomeric infusion pumps, administered to patients admitted to the Home Hospitalisation Unit of a tertiary hospital for 3 years and to analyse clinical evolution and mortality. METHOD: Retrospective observational study. The medical history of the patients included in the study was reviewed. Information was obtained on personal history, antimicrobial therapy received, and clinical evolution. Statistical analysis was performed using SPSS® 19 software. RESULTS: 81 patients were included, 61.7% men, with a mean age of 73.5±17.5â¯years. The most frequent comorbidities were diabetes mellitus (30.9%) and chronic kidney disease (28.4%). Patients received a mean of 11.9±8.5â¯days of antibiotic treatment in an elastomeric infusion pump. The main focus of infection was respiratory (27.2%), followed by bacteremia (16%) and skin and soft tissue infections (12.3%). Of the infections, 65.4% were monomicrobial, with Pseudomonas aeruginosa being the main microorganism involved (39.6%). The most commonly used antimicrobial was piperacillin/tazobactam (33.3%). The clinical course was good in 85.2% of the patients, but the mortality rate in the 30â¯days following the end of treatment was 24.7%. In the univariate analysis, a history of neoplasia in the last 5â¯years (p=.01) and having received fewer days of antibiotic therapy prior to the start of outpatient antimicrobial therapy in infusion pump (p=.04) were associated with worse clinical outcome. Age over 80â¯years was associated with better outcome (p=.03). The diagnosis of heart failure was associated with higher mortality (p=.026) and patients from surgical services, with lower mortality (p=.047). In the multivariate analysis, the presence of neoplasia was associated with unfavourable evolution (p=.012) and heart failure with higher mortality (p=.027). CONCLUSIONS: Outpatient antimicrobial therapy in elastomeric infusion pumps is an alternative in patients requiring prolonged intravenous treatment, and age is not a conditioning factor for inclusion in these programs. However, the presence of certain comorbidities can negatively affect the clinical course and mortality of patients.
Assuntos
Antibacterianos , Terapia por Infusões no Domicílio , Bombas de Infusão , Humanos , Estudos Retrospectivos , Masculino , Feminino , Idoso , Antibacterianos/administração & dosagem , Antibacterianos/uso terapêutico , Idoso de 80 Anos ou mais , Pessoa de Meia-Idade , ElastômerosRESUMO
OBJECTIVES: To describe the experience of home antibiotic infusion therapy using elastomeric infusion pumps, administered to patients admitted to the Home Hospitalization Unit of a tertiary hospital for three years and to analyse clinical evolution and mortality. METHOD: Retrospective observational study. The medical history of the patients included in the study was reviewed. Information was obtained on personal history, antimicrobial therapy received and clinical evolution. Statistical analysis was performed using SPSS® 19 software. RESULTS: Eighty-one patients were included, 61.7% men, with a mean age of 73.5 ± 17.5 years. The most frequent comorbidities were diabetes mellitus (30.9%) and chronic kidney disease (28.4%). Patients received a mean of 11.9 ± 8.5 days of antibiotic treatment in an elastomeric infusion pump. The main focus of infection was respiratory (27.2%), followed by bacteremia (16%) and skin and soft tissue infections (12.3%). Of the infections, 65.4% were monomicrobial, with Pseudomonas aeruginosa being the main microorganism involved (39.6%). The most commonly used antimicrobial was piperacillin/tazobactam (33.3%). The clinical course was good in 85.2% of the patients, but the mortality rate in the 30 days following the end of treatment was 24.7%. In the univariate analysis, a history of neoplasia in the last 5 years (p = 0.01) and having received fewer days of antibiotic therapy prior to the start of outpatient antimicrobial therapy in infusion pump (p = 0.04) were associated with worse clinical outcome. Age over 80 years was associated with better outcome (p = 0.03). The diagnosis of heart failure was associated with higher mortality (p = 0.026) and patients from surgical services, with lower mortality (p = 0.047). In the multivariate analysis, the presence of neoplasia was associated with unfavorable evolution (p = 0.012) and heart failure with higher mortality (p = 0.027). CONCLUSIONS: Outpatient antimicrobial therapy in elastomeric infusion pumps is an alternative in patients requiring prolonged intravenous treatment, and age is not a conditioning factor for inclusion in these programs. However, the presence of certain comorbidities can negatively affect the clinical course and mortality of patients.
Assuntos
Antibacterianos , Elastômeros , Terapia por Infusões no Domicílio , Bombas de Infusão , Humanos , Estudos Retrospectivos , Masculino , Idoso , Feminino , Antibacterianos/administração & dosagem , Antibacterianos/uso terapêutico , Idoso de 80 Anos ou mais , Pessoa de Meia-IdadeRESUMO
Resumo Objetivo Elaborar e validar tecnologias educativas para o cuidado domiciliar de pessoas com hemofilia em infusão endovenosa do fator de coagulação. Método Estudo metodológico, desenvolvido em três etapas: elaboração de tecnologias educativas, avaliação de conteúdo e aparência por juízes e apreciação por pessoas com hemofilia. As tecnologias educativas − cartilha e infográfico − foram elaboradas mediante revisão de literatura. Na etapa de avaliação com juízes, foi utilizada a técnica Delphi em duas rodadas, por meio do Índice de Validade de Conteúdo, concordância superior a 0,80 em relação a clareza de linguagem, pertinência prática e relevância teórica. Na avaliação com o público-alvo, foi considerado o nível de concordância de respostas positivas maior ou igual a 80% nos itens de organização, o estilo de escrita, a aparência e a motivação para a leitura. Resultados A cartilha apresentou índice de validade de conteúdo global de 0,88 na primeira rodada e 0,98 na segunda; e o infográfico, 0,88 na primeira rodada e 0,97 na segunda. Na apreciação das tecnologias educativas pelo público-alvo, o nível de concordância das respostas positivas foi superior a 80%. Conclusão Este estudo elaborou tecnologias educativas, cartilha e infográfico, que poderão contribuir com a adesão ao tratamento e promoção do cuidado, por meio de padronização das orientações às pessoas com hemofilia em infusão endovenosa domiciliar.
Resumen Objetivo Elaborar y validar tecnologías educativas para el cuidado domiciliario de personas con hemofilia sobre la infusión intravenosa domiciliaria del factor de coagulación. Métodos Estudio metodológico desarrollado en tres etapas: elaboración de tecnologías educativas, evaluación de contenido y apariencia por jueces y valoración por parte de personas con hemofilia. Las tecnologías educativas (cartilla e infográfico) fueron elaboradas mediate revisión de literatura. En la etapa de evaluación con jueces, se utilizó el método Delphi en dos rondas, por medio del Índice de Validez de Contenido, concordancia superior a 0,80 con relación a la claridad del lenguaje, pertinencia práctica y relevancia teórica. En la evaluación con el público destinatario, se consideró el nivel de concordancia de respuestas positivas mayor o igual a 80 % en los ítems organización, estilo de escritura, apariencia y motivación para lectura. Resultados La cartilla presentó un Índice de Validez de Contenido global de 0,88 en la primera ronda y 0,98 en la segunda. El infográfico presentó 0,88 en la primaria ronda y 0,97 en la segunda. En la valoración de las tecnologías educativas por el público destinatario, el nivel de concordancia de las respuestas positivas fue superior al 80 %. Conclusión En este estudio se elaboraron tecnologías educativas, cartilla e infográfico, que podrán contribuir con la adherencia al tratamiento y promoción del cuidado, mediante la estandarización de las instrucciones a personas con hemofilia sobre infusión intravenosa domiciliaria.
Abstract Objective To develop and validate educational technologies for home care of people with hemophilia on intravenous infusion of clotting factor. Method This is a methodological study, developed in three stages: development of educational technologies, content and appearance assessment by judges, and appraisal by people with hemophilia. The educational technologies - a booklet and an infographic - were developed through a literature review. In the assessment stage with judges, the Delphi technique was used in two rounds, through Content Validity Index, agreement greater than 0.80 in regarding clarity of language, practical relevance, and theoretical relevance. In the assessment with the target audience, the level of agreement of positive responses greater than or equal to 80% in the items of organization, writing style, appearance and motivation for reading was considered. Results The booklet presented a global content validity index of 0.88 in the first round and 0.98 in the second; and the infographic, 0.88 in the first round and 0.97 in the second. In the assessment of educational technologies by the target audience, the level of agreement of positive responses was higher than 80%. Conclusion This study developed educational technologies, a booklet and an infographic, which could contribute to adherence to treatment and promotion of care, by standardizing the guidelines for people with hemophilia in intravenous infusion at home.
Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Infusões Intravenosas , Fatores de Coagulação Sanguínea , Terapia por Infusões no Domicílio , Tecnologia Educacional , Materiais Educativos e de Divulgação , Hemofilia A/terapia , Assistência DomiciliarRESUMO
Fabry disease is an X-linked lysosomal storage disorder caused by inherited deficiency of the enzyme α-galactosidase A. Enzyme replacement treatment using agalsidase alfa significantly reduces pain, improves cardiac function and quality of life, and slows renal deterioration. Nevertheless, it is a life-long treatment which requires regular intravenous infusions and entails a great burden for patients. Our objective was to evaluate retrospectively the safety and tolerability of the home infusion of agalsidase alfa in patients with Fabry disease in Argentina. We evaluated all the patients with Fabry disease who received home infusion with agalsidase alfa 0.2 mg/kg between January 2005 and June 2011. The program included 87 patients; 51 males (mean age: 30 years) and 36 females (mean age: 34 years). A total of 5229 infusions (mean: 59 per patient; range: 1-150) were administered. A total of 5 adverse reactions were seen in 5 patients (5.7% of patients and 0.9% of the total number of infusions). All were mild in severity and resolved by reducing the rate of infusion and by using antihistaminics. All these 5 patients were positive for IgG antibodies, but none of them presented IgE antibodies and none suffered an anaphylactic shock. In our group 18 patients were switched from agalsidase beta to agalsidase alfa without complications. Home infusion with agalsidase alfa is safe, well tolerated and is associated to high compliance.
La enfermedad de Fabry es un trastorno de almacenamiento lisosomal hereditario ligado al cromosoma X ocasionado por el déficit de la enzima alfa galactosidasa A. La terapia de reemplazo enzimático utilizando agalsidasa alfa reduce significativamente el dolor, mejora la función cardíaca y la calidad de vida y enlentece el deterioro renal. Sin embargo, es un tratamiento de por vida que requiere infusiones intravenosas regulares y supone una gran carga para los pacientes. Nuestro objetivo fue evaluar retrospectivamente la tolerabilidad y la seguridad del procedimiento de infusión domiciliaria de agalsidasa alfa en pacientes con enfermedad de Fabry en Argentina. Evaluamos a todos los pacientes con enfermedad de Fabry que recibieron infusiones domiciliarias de 0.2 mg/kg de agalsidasa alfa entre enero del 2005 y junio del 2011. El programa incluyó 87 pacientes; 51 hombres (edad media: 30 años) y 36 mujeres (edad media: 34 años). Se administraron un total de 5229 infusiones (media: 59 por paciente; rango: 1-50). Se observaron un total de 5 reacciones adversas en 5 pacientes (5.7% de los pacientes y 0.9 % del número total de infusiones). Todas fueron de gravedad leve y se resolvieron reduciendo la velocidad de la infusión o usando antihistamínicos. Los 5 pacientes fueron positivos para anticuerpos IgG, pero ninguno presentó anticuerpos IgE o sufrió un shock anafiláctico. En nuestro grupo, 18 pacientes fueron cambiados de agalsidasa beta a agalsidasa alfa sin complicaciones. La infusión domiciliaria de agalsidasa alfa es segura, bien tolerada y logra una alta adherencia al tratamiento.
Assuntos
Adolescente , Adulto , Idoso , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Terapia de Reposição de Enzimas/métodos , Doença de Fabry/tratamento farmacológico , Terapia por Infusões no Domicílio , alfa-Galactosidase/uso terapêutico , Argentina , Terapia por Infusões no Domicílio/efeitos adversos , Infusões Intravenosas , Isoenzimas/uso terapêutico , Estudos Retrospectivos , Resultado do TratamentoRESUMO
Los objetivos fueron, determinar la percepción del paciente que recibe quimioterapia ambulatoria sobre su calidad de vida en el HAMA e Identificar la percepción en la necesidad fisiológica, seguridad, social, estima y autorrealización. Material y Método: El estudio fue de nivel aplicativo, tipo cuantitativo, método descriptivo de corte transversal. La población estuvo constituida por 30 pacientes que reciben quimioterapia ambulatoria. La técnica fue la entrevista y el instrumento una escala modificada tipo Lickert, considerando el consentimiento informado. Resultados: Del 100 por ciento (30), 53.3 por ciento (16) tienen un percepción medianamente favorable, 26 por ciento (8) desfavorable, 20 por ciento (6) favorable. En relación a la necesidad fisiológica, el 63.3 por ciento (19) es medianamente favorable, 23.3 por ciento (7) desfavorable y 13 por ciento (4) favorable. En cuanto a la necesidad de seguridad, 56 por ciento (17) es medianamente favorable; 23 por ciento (7) favorable y 20 por ciento (6) desfavorable .En la necesidad social; 70 por ciento (21) es medianamente favorable; 17 por ciento (5) favorable y 3,3 por ciento (4) desfavorable; en la necesidad de estima; 53.3 por ciento (16) es medianamente favorable, 27 por ciento (8) favorable y 20 por ciento ( 6) desfavorable y en la necesidad de autorrealización; 56.7 por ciento (17) es medianamente favorable, 23.3 por ciento favorable y 20 por ciento (6) desfavorable. Conclusiones: Un porcentaje considerable de pacientes que reciben quimioterapia ambulatoria tienen una percepción medianamente favorable, en aspectos fisiológicos, seguridad, social, estima y autorrealización referido a que los pacientes han presentado muchas náuseas en su última sesión de quimioterapia. Tuvieron miedo desde el día en que le informaron el tipo de tratamiento que llevarían; les resulta difícil entretenerse en sus tiempos de ocio por los efectos de la quimioterapia desde que inició su tratamiento. Amanecen con ganas de morirse...
The aims were, to determine the perception of the patient who receives ambulatory chemotherapy on his quality of life in the HAMA and to identify the perception in the physiological need, safety, socially, he estimates and auto-realization. Material and Method: The study was of applicative level, quantitative type, descriptive method of transverse court. The population was constituted by 30 patients who receive ambulatory chemotherapy. The technology was the interview and the instrument a modified scale type Lickert, considering the informed assent. Results: Of 100 per cent (30), 53.3 per cent (16) they have one moderately favorable perception, 26 per cent (8) unfavorably, 20 per cent (6) favorably. In relation to the physiological need, 63.3 per cent (19) is moderately favorable, 23.3 per cent (7) unfavorably and 13 per cent (4) favorably. As for the safety need, 56 per cent (17) is moderately favorable; 23 per cent (7) favorable and 20 per cent (6) unfavorable. En the social need; 70 per cent (21) is moderately favorable; 17 per cent (5) favorable and 3.3 per cent (4) unfavorable; in the need of esteem; 53.3 per cent (16) is moderately favorable, 27 per cent (8) favorably and 20 per cent (6) unfavorably and in the need of auto-realization; 56.7 per cent (17) is moderately favorable, 23.3 per cent favorable and 20 per cent (6) unfavorably. Conclusions: A considerable percentage of patients who receive ambulatory chemotherapy have a moderately favorable perception, in physiological aspects, safety, socially, he estimates and auto-realization recounted to that the patients have presented many nauseas in his last session of chemotherapy, they were afraid from the day that they said to him that it would take the treatment, it turns out to them difficult to amuse in his times of leisure for the effects of the chemotherapy, since I initiate his treatment dawns with desire of dying, feels that there are few persons who estimate it and the effects of the...
Assuntos
Masculino , Feminino , Humanos , Adulto , Pessoa de Meia-Idade , Idoso , Qualidade de Vida , Terapia por Infusões no Domicílio , Tratamento Farmacológico , Estudos TransversaisRESUMO
El objetivo fue determinar la opinión de los familiares del paciente pediátrico oncológico sobre la calidad de atención de enfermería en el servicio de quimioterapia ambulatoria en el instituto Nacional de Enfermedades Neoplásicas 2011. Material y Método: el estudio fue de nivel aplicativo, tipo cuantitativo, método descriptivo de corte transversal. La muestra estuvo conformada por 40 familiares. La técnica fue la entrevista y el instrumento una escala de Lickert modificada aplicado previo consentimiento informado. Resultados: Del 100 por ciento (40), 62 por ciento (25) tienen una opinión medianamente favorable, 25 por ciento (10) favorable y 13 por ciento (5) desfavorable. En la dimensión oportuna 43 por ciento (17), tienen una opinión medianamente favorable a desfavorable; de igual modo 50 por ciento (20) en la dimensión humana; 55 por ciento (22) en la dimensión segura; 50 por ciento (20) en la dimensión continua. Conclusiones: El mayor porcentaje de los familiares tienen una opinión medianamente favorable a desfavorable, de igual manera en la dimensión oportuna, humana, segura y continua referido a que no recibe una atención con respeto, no recibe una atención de acuerdo a sus necesidades en forma rápida, no se preocupa por la alimentación de su niño(a) cuando recibe su quimioterapia, no le brinda educación individual. Sin embargo existe un menor porcentaje que presentan una opinión favorable referido a que la enfermera actúa con discreción cuando el caso lo amerita, canaliza con rapidez la vía de su niño(a), se muestra amable y la entrega las indicaciones después de su quimioterapia.
The objective was to determine the views of pediatric oncology patient's family about the quality of nursing care in the ambulatory chemotherapy service at the National Institute of Neoplastic Diseases 2011. Material and Methods: The study was level application, quantitative, cross-sectional descriptive method. The sample consisted of 40 families. The technique was the interview and instrument modified Lickert scale applied informed consent. Results: of 100 per cent (40), 62 per cent (25) have a fairly favorable opinion, 25 per cent (10) in favor and 13 per cent (5) unfavorable. In dimension timely 43 per cent (17) have a fairly favorable to unfavorable opinion, likewise 50 per cent (20) in the human dimension, 55 per cent (22) in the safe dimension and 50 per cent (20) in the continuous dimension. Conclusions: the highest percentage of families have a fairly favorable to unfavorable opinion, just as in the dimension timely, humane, safe and continuously referred to not receive question with respect, do not receive care according to their needs quickly, no worries about feeding your child when receiving their chemotherapy, does not provide individual education. However, there is a smaller percentage having a favorable opinion referred to the nurse acts with discretion when the case warrants, quickly channeled via its child, is shown delivering friendly and indications after chemotherapy.