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1.
Injury ; 50(11): 2103-2107, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31530380

RESUMO

INTRODUCTION: In the staged management of tibial pilon fractures, overlap between definitive internal fixation and external fixation pin sites has been investigated as a risk factor for infection with equivocal conclusions. Our aim was to determine if overlap or proximity of definitive internal fixation to external fixation pin sites influences the risk of deep infection. PATIENTS AND METHODS: We reviewed 280 AO/OTA 43B or 43C type distal tibia fractures in 277 patients at two level-one trauma centers. Patients underwent staged management using early temporizing external fixation followed by definitive open reduction and plate fixation. Primary outcome was the association between pin site overlap and the development of deep infection. Secondary outcome was the relationship between development of deep infection and the distance from pin site to definitive fixation. RESULTS: The average duration between external fixation and definitive internal fixation was 14 days. 24% of fractures developed deep infection requiring surgical intervention. There was no association between pin site overlap and the development of deep infection (p = 0.18). There was no relationship between infection and the distance between proximal plate extent and pin site (p = 0.13). DISCUSSION: We identified no association between pin site overlap and the development of deep infection. We suggest that temporizing external fixation pins should be placed so as to obtain optimal stability of the construct with lesser emphasis on aiming to be absolutely outside the zone of future fixation. LEVEL OF EVIDENCE: Level III Therapeutic Retrospective Comparative study.


Assuntos
Traumatismos do Tornozelo/cirurgia , Fixadores Externos/microbiologia , Fixação de Fratura/métodos , Fraturas Expostas/cirurgia , Infecção da Ferida Cirúrgica/microbiologia , Fraturas da Tíbia/cirurgia , Cicatrização/fisiologia , Adulto , Traumatismos do Tornozelo/microbiologia , Traumatismos do Tornozelo/patologia , Pinos Ortopédicos/microbiologia , Desbridamento/métodos , Feminino , Fixação de Fratura/efeitos adversos , Fixação de Fratura/instrumentação , Fraturas Expostas/microbiologia , Fraturas Expostas/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Infecção da Ferida Cirúrgica/prevenção & controle , Fraturas da Tíbia/microbiologia , Fraturas da Tíbia/patologia , Resultado do Tratamento
3.
Enferm Infecc Microbiol Clin ; 29(7): 550-1, 2011.
Artigo em Espanhol | MEDLINE | ID: mdl-21497422
4.
Acta Orthop Belg ; 75(5): 699-704, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19999887

RESUMO

Total talar dislocation is a rare injury, which is usually open and with associated fractures. We report two cases of open anterolateral talar extrusions following high-energy traffic accidents. Both were treated with wound debridement, joint irrigation, closed reduction and external fixation. At 12 months follow-up, both patients had pain-free motion of the ankle without any signs of avascular necrosis or arthritis.


Assuntos
Traumatismos do Tornozelo/cirurgia , Luxações Articulares/cirurgia , Tálus/lesões , Acidentes de Trânsito , Adulto , Traumatismos do Tornozelo/microbiologia , Desbridamento , Fixação de Fratura , Humanos , Luxações Articulares/microbiologia , Masculino , Pessoa de Meia-Idade , Irrigação Terapêutica
6.
Med Mal Infect ; 35(7-8): 417-8, 2005.
Artigo em Francês | MEDLINE | ID: mdl-15982842
7.
Mycoses ; 46(5-6): 233-6, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12801370

RESUMO

Scedosporium prolificans infections of normal hosts usually require extensive debridement and sometimes amputation to effect cure, due to the intrinsic resistance of this species to available antifungal agents. Newer agents have not tested favourably. Variable results are obtained with voriconazole, and 100% resistance is described with echinocandins. Itraconazole and terbinafine has offered synergy against various moulds including S. prolificans. In vivo success is reported with the azole/terbinafine combination in S. apiospermum pulmonary infection and Pythium insidiosum periorbital cellulitis. We report a case of orthopaedic infection in a non-immunocompromised host with S. prolificans, in which the combinations of itraconazole/terbinafine and voriconazole/terbinafine showed synergy in vitro, and success was achieved without radical surgery, using voriconazole and terbinafine.


Assuntos
Traumatismos do Tornozelo/tratamento farmacológico , Antifúngicos/uso terapêutico , Micetoma/tratamento farmacológico , Naftalenos/uso terapêutico , Pirimidinas/uso terapêutico , Scedosporium , Triazóis/uso terapêutico , Idoso , Traumatismos do Tornozelo/microbiologia , Desbridamento , Sinergismo Farmacológico , Quimioterapia Combinada , Humanos , Masculino , Testes de Sensibilidade Microbiana , Micetoma/microbiologia , Micetoma/cirurgia , Scedosporium/efeitos dos fármacos , Terbinafina , Voriconazol
8.
J Clin Gastroenterol ; 27(4): 364-6, 1998 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9855273

RESUMO

Septic arthritis is usually of hematogenous origin and is increasingly being reported in elderly patients, who often have underlying medical conditions such as diabetes or alcoholism. We report a 62-year-old patient with alcoholic liver disease who presented with Escherichia coli bacteremia and septic arthritis in a previously fractured ankle. There are scarce reports of infectious arthritis in cirrhotic patients, but this is the first report of arthritis after a primary enteric bacteremia. We believe that the patient described here developed E. coli bacteremia as a result of bacterial overgrowth and translocation related to alcoholic liver disease and cirrhosis. The resulting bacteremia resulted in the development of infection in the left ankle, which had preexisting disease and was thus vulnerable. This case provides further evidence for the mode of infection being bacteremia in cirrhotic patients. In patients with cirrhosis and fever, a high index of suspicion is required for joint infection as a potential cause of fever or deterioration in the cirrhotic's patient general condition.


Assuntos
Artrite Infecciosa/diagnóstico , Artrite Infecciosa/microbiologia , Bacteriemia/diagnóstico , Bacteriemia/microbiologia , Infecções por Escherichia coli/complicações , Infecções por Escherichia coli/diagnóstico , Cirrose Hepática Alcoólica/complicações , Traumatismos do Tornozelo/microbiologia , Artrite Infecciosa/complicações , Bacteriemia/complicações , Diagnóstico Diferencial , Humanos , Cirrose Hepática Alcoólica/microbiologia , Masculino , Pessoa de Meia-Idade
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